Scribd Logo
Upload

Welcome to Scribd!

  • 261 views

    The Eukaryotic Cell Cycle and Cancer

    Uploaded by

    Karen Sinor
    The document provides an overview of the eukaryotic cell cycle and its relationship to cancer. It discusses how cell division, differentiation, and apoptosis are important for multicellular organisms. The cell cycle consists of interphase, where the cell grows and duplicates its components, and mitosis, where the cell divides. Cancer occurs when cell cycle regulation is disrupted, such as through mutations in proto-oncogenes which stimulate cell division or tumor suppressor genes which normally inhibit the cell cycle. Improperly regulated cells can form tumors when they continue to grow and divide uncontrollably.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd

    The Eukaryotic Cell Cycle and Cancer

    Uploaded by

    Karen Sinor
    261 views3 pages
    The document provides an overview of the eukaryotic cell cycle and its relationship to cancer. It discusses how cell division, differentiation, and apoptosis are important for multicellular organisms. The cell cycle consists of interphase, where the cell grows and duplicates its components, and mitosis, where the cell divides. Cancer occurs when cell cycle regulation is disrupted, such as through mutations in proto-oncogenes which stimulate cell division or tumor suppressor genes which normally inhibit the cell cycle. Improperly regulated cells can form tumors when they continue to grow and divide uncontrollably.

    Original Title

    CellCycleOverview-StudentWS-CL

    Copyright

    © © All Rights Reserved

    Available Formats

    PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    The document provides an overview of the eukaryotic cell cycle and its relationship to cancer. It discusses how cell division, differentiation, and apoptosis are important for multicellular organisms. The cell cycle consists of interphase, where the cell grows and duplicates its components, and mitosis, where the cell divides. Cancer occurs when cell cycle regulation is disrupted, such as through mutations in proto-oncogenes which stimulate cell division or tumor suppressor genes which normally inhibit the cell cycle. Improperly regulated cells can form tumors when they continue to grow and divide uncontrollably.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    261 views3 pages

    The Eukaryotic Cell Cycle and Cancer

    Uploaded by

    Karen Sinor
    The document provides an overview of the eukaryotic cell cycle and its relationship to cancer. It discusses how cell division, differentiation, and apoptosis are important for multicellular organisms. The cell cycle consists of interphase, where the cell grows and duplicates its components, and mitosis, where the cell divides. Cancer occurs when cell cycle regulation is disrupted, such as through mutations in proto-oncogenes which stimulate cell division or tumor suppressor genes which normally inhibit the cell cycle. Improperly regulated cells can form tumors when they continue to grow and divide uncontrollably.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 3

    The Eukaryotic Cell Cycle and Cancer

    Overview Click & Learn


    Student Worksheet

    INTRODUCTION
    This handout complements the Click & Learn The Eukaryotic Cell Cycle and Cancer and is intended as a
    straightforward introduction to the cell cycle and how it relates to cancer. For a more comprehensive student
    handout, please see the in-depth version.

    PROCEDURE
    Follow the instructions as you proceed through the Click & Learn and answer the questions in the spaces below.

    Click on the “Background” tab on the right side. Read the information and watch the videos.
    1. Why is cell division important for both single-celled and multicellular organisms?

    2. Why does cell division remain important to an adult organism even after it is fully developed?

    3. Cells divide, differentiate, or die. What is differentiation?

    4. What is apoptosis? What is its purpose?

    5. What are cell cycle regulators?

    6. What happens if cell cycle regulators don’t function properly?

    Click on the purple section labeled “Cell Cycle Phases” as well as the words “Mitosis” and “Interphase” to read
    an overview of the cell cycle. You can also click on the various phases.
    7. Cells go through periods of growth and division. Cell division occurs during ____________________.
    The rest of the cell cycle is called interphase, during which (use the blank below to complete the sentence)

    Cell Cycle Updated February 2020


    www.BioInteractive.org Page 1 of 3
    Click & Learn
    The Eukaryotic Cell Cycle and Cancer – Overview Student Worksheet
    8. Fill in the details about what happens during the three phases of interphase labeled in the diagram.

    9. In general, what is the purpose of a checkpoint in the cell cycle?

    10. What is the G0 phase of the cell cycle?


    a. Which factors determine whether a cell enters G0?

    b. Can cells leave G0?

    Click on “Cell Cycle Regulators and Cancer” in the center purple circle. Read the “Regulators Overview” and
    then read through the “Cancer Overview” and watch the videos.
    11. What are cell cycle regulators?

    a. Stimulating proteins are encoded by ______________________________________.

    Examples include: _____________________________________________________

    b. Inhibitory proteins are encoded by ________________________________________.

    Examples include: _____________________________________________________


    Cell Cycle Updated February 2020
    www.BioInteractive.org Page 2 of 3
    Click & Learn
    The Eukaryotic Cell Cycle and Cancer – Overview Student Worksheet
    12. Cancer is the result of an improperly regulated cell cycle. Describe two reasons why cells can form tumors.

    13. In some types of colon cancer, stem cells have a mutation in the APC gene. What happens if the APC gene is
    mutated?

    14. Normally, proto-oncogenes stimulate the cell cycle. What are oncogenes and how do they affect the cell
    cycle?

    a. To cause cancer, proto-oncogenes require _________ allele(s) to be mutated and therefore are
    considered ______________________ . The mutation results in a ________ of function.
    15. Normally, tumor suppressor genes inhibit the cell cycle. How do mutated tumor suppressor genes affect the
    cell cycle?

    a. To cause cancer, tumor suppressor genes require __________ allele(s) to be mutated and therefore are
    considered ______________________ . The mutation results in a ________ of function.

    Cell Cycle Updated February 2020


    www.BioInteractive.org Page 3 of 3

    You might also like