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    COURSE TASK 6 - Degenerative Table Summary

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    Jordz Placi
    This document summarizes several autoimmune diseases including Parkinson's disease (PD), Huntington's disease (HD), multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), myasthenia gravis (MG), and Guillain-Barré syndrome (GBS). It provides key details about each disease such as typical age of onset, affected gender, potential causes, diagnostic tests, common symptoms, and life expectancy. The diseases described range from progressive neurological disorders affecting movement and cognition to peripheral nerve inflammation.

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    COURSE TASK 6 - Degenerative Table Summary

    Uploaded by

    Jordz Placi
    873 views2 pages
    This document summarizes several autoimmune diseases including Parkinson's disease (PD), Huntington's disease (HD), multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), myasthenia gravis (MG), and Guillain-Barré syndrome (GBS). It provides key details about each disease such as typical age of onset, affected gender, potential causes, diagnostic tests, common symptoms, and life expectancy. The diseases described range from progressive neurological disorders affecting movement and cognition to peripheral nerve inflammation.

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    COURSE TASK 6_Degenerative Table Summary

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    This document summarizes several autoimmune diseases including Parkinson's disease (PD), Huntington's disease (HD), multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), myasthenia gravis (MG), and Guillain-Barré syndrome (GBS). It provides key details about each disease such as typical age of onset, affected gender, potential causes, diagnostic tests, common symptoms, and life expectancy. The diseases described range from progressive neurological disorders affecting movement and cognition to peripheral nerve inflammation.

    Copyright:

    © All Rights Reserved
    Download as DOC, PDF, TXT or read online from Scribd
    Download as doc, pdf, or txt
    873 views2 pages

    COURSE TASK 6 - Degenerative Table Summary

    Uploaded by

    Jordz Placi
    This document summarizes several autoimmune diseases including Parkinson's disease (PD), Huntington's disease (HD), multiple sclerosis (MS), amyotrophic lateral sclerosis (ALS), myasthenia gravis (MG), and Guillain-Barré syndrome (GBS). It provides key details about each disease such as typical age of onset, affected gender, potential causes, diagnostic tests, common symptoms, and life expectancy. The diseases described range from progressive neurological disorders affecting movement and cognition to peripheral nerve inflammation.

    Copyright:

    © All Rights Reserved
    Download as DOC, PDF, TXT or read online from Scribd
    Download as doc, pdf, or txt
    of 2

    plasmapheresis AUTOIMMUNE DISEASES thymectomy

    PD HD MS ALS MG GBS
    progressive disorder with chronic, progressive progressive, w/ loss of motor neurons in disturbance in the symmetrical, bilateral,
    degeneration of the nerve hereditary dse w/ demyelinating dse of the anterior horn of the transmission of impuled peripheral (PNS)
    cells in the basal ganglia progressive the CNS spinal cord & motor nuclei from nerve to mucle cells polyneuritis char. by
     involuntary  of the lower brainstem @ the neuromuscular ascending paralysis
    resulting in generalized choreiform movt & results in impaired junction= PNS
    disorder on muscular fx dementia transmission of nerve 
    impulses causing extensive muscle
    weakness
    in dopamine GABA & Ach demyelination motor neurons of the voluntary muscles are demyelination
    anterior horn of the spinal affected, esp those
    cord and motor nuclei of innervated by the cranial
    lower brainstem dies & nerves
    men>women men=women women>men men>women women>men men=women
    AGE older population: 50 y.o. onset 35-45 y.o. 20-40 y.o. onset 50-60 y.o. W: 15-35 y.o. occurs at any age
    some @ 30 y.o. 10% are children M: 40 y.o.
    CAUSE UKNOWN researches: may also be a slow- also a theory: w/ antecedent
    sometimes disorder is glutamine (bldg block growing virus overexcitation of nerve viralinfection
    postencephalitic, toxic, of CHON abN collect cells by glutamate
    arteriosclerotic, traumatic, in the cell nuclei 
    or drug induced causing cell death Cell injury
    =reason CHON
    destroys only certain
    brain cells is
    UNKNOWN
    DXTIC TESTS X X CSF studies X Tensilon test CSF studies: ↑CHON
    EEG EMG EMG: slow nerve
    CTscan/ MRI Blood test conduction
    -w/ anti-acetylcholine
    receptor antibodies
    S/SXS 3 cardinal signs: tremors, progressive mental 1st sx: weakness of arms, trunk & 1st noticeable sx: 1st sx: clumsiness
    rigidity, bradykinesia status changes visual disturbance legs weakness of eye ascending, symmetrical
    Others: masklike face,   dysarthia, dysphagia, muscles/ ptosis motor weakness in > 1
    stooped posture, propulsive dementia , blurred vision spasticity limb
    gait choreiform movts, fits scotomas dysphagia 
    of anger, suicidal diplopia slurred speech cranial nerve
    depression  involvement: dysphagia
    touch,pain & temp & 
    posn sensations paralysis ascnt to the
     resp muscles
    impaired motor fx 
    impaired cerebellar fx absent DTRs
    DEATH occurs 10-20 yrs 3 yrs after onset of dse may take only a few
    after inset of dse hours to reach the most
    severe sxs

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