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    Reading A. Read The Text Carefully! Normal Pregnancy

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    Senda Risanda
    1) Normal human pregnancy is associated with evidence of complement activation, as seen by increased concentrations of C3a, C4a, and C5a in maternal circulation. 2) The study aimed to determine if normal pregnancy is linked to complement activation in the mother's bloodstream. 3) The researchers propose that the physiological activation of the complement system during pregnancy acts to protect the host against infection.

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    Reading A. Read The Text Carefully! Normal Pregnancy

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    Senda Risanda
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    1) Normal human pregnancy is associated with evidence of complement activation, as seen by increased concentrations of C3a, C4a, and C5a in maternal circulation. 2) The study aimed to determine if normal pregnancy is linked to complement activation in the mother's bloodstream. 3) The researchers propose that the physiological activation of the complement system during pregnancy acts to protect the host against infection.

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    NORMAL PREGNANCY

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    1) Normal human pregnancy is associated with evidence of complement activation, as seen by increased concentrations of C3a, C4a, and C5a in maternal circulation. 2) The study aimed to determine if normal pregnancy is linked to complement activation in the mother's bloodstream. 3) The researchers propose that the physiological activation of the complement system during pregnancy acts to protect the host against infection.

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    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    256 views2 pages

    Reading A. Read The Text Carefully! Normal Pregnancy

    Uploaded by

    Senda Risanda
    1) Normal human pregnancy is associated with evidence of complement activation, as seen by increased concentrations of C3a, C4a, and C5a in maternal circulation. 2) The study aimed to determine if normal pregnancy is linked to complement activation in the mother's bloodstream. 3) The researchers propose that the physiological activation of the complement system during pregnancy acts to protect the host against infection.

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    of 2

    Tuesday, 30 June 2020

    READING
    a. Read the text carefully!
    NORMAL PREGNANCY
    By: KARINA RICHANI
    BACKGROUND: The complement system, a major component of innate immunity, has
    recently been implicated in the mechanisms of fetal loss and placental inflammation in the
    anti-phospholipid antibody syndrome. Inhibition of complement has been proposed as an
    absolute requirement for normal pregnancy. Yet, pregnancy is characterized by a generalized
    activation of the innate immune system. This study was conducted to determine whether
    normal pregnancy is associated with complement activation in the maternal circulation.
    CONCLUSION: 1) Normal human pregnancy is associated with evidence of complement
    activation, as determined by increased concentrations of the anaphylatoxins C3a, C4a and
    C5a in the maternal circulation; and 2) We propose that physiologic activation of the
    complement system during pregnancy is a compensatory mechanism aimed to protect the
    host against infection.
    b. Answer the questions based on the text above!
    1. What is pregnancy characterised?
    Pregnancy characterised by a generalized activation of the innate immune system
    2. What was the study in this article conducted to?
    This study was conducted to determine whether normal pregnancy is associated
    with complement activation in the maternal circulation.
    3. What is the conclusion of study?
    1) Normal human pregnancy is associated with evidence of complement activation,
    as determined by increased concentrations of the anaphylatoxins C3a, C4a and C5a
    in the maternal circulation; and 2) We propose that physiologic activation of the
    complement system during pregnancy is a compensatory mechanism aimed to
    protect the host against infection.
    4. “We propose that physiologic activation.........” (paragraph 2) What does the
    underlined word refer to?
    KARINA RICHANI Normal human pregnancy researcher
    5. “This study was conducted to determine whether normal pregnancy....” What is
    the similar meaning of the underlined word?
    Behavior and manage
    VOCABULARY
    Look these words up in dictionary!
    a. innate immunity: imun bawaan / kekebalan bawaan
    b. placental inflammation: peradangan plasenta
    c. anti-phospholipid: antifosfolipid/ gangguan pada sistem pembekuan darah
    d. antibody syndrome: gangguan antibodi
    e. complement activation: aktivasi komplemen
    f. maternal circulation: sirkulasi ibu
    g. anaphylatoxins: Anafilatoksin / fragmen protein yang terbentuk saat sistem komplemen
    teraktivasi (C3a, C4a, C5a)
    h. gestational age: usia kehamilan

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