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    Spirin Capsula: Storage: Store in A

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    James Azurin
    This document summarizes a student's laboratory preparation of aspirin capsules. The student prepared 6 aspirin capsules containing a total of 0.56g of aspirin and 1.38g of starch as filler. The capsules were produced using a capsule molder and packaged in a bottle for storage. The student reflected on learning how to prepare capsules and highlighted that these skills will be useful for compounding medications as a future pharmacist.

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    Spirin Capsula: Storage: Store in A

    Uploaded by

    James Azurin
    40 views3 pages
    This document summarizes a student's laboratory preparation of aspirin capsules. The student prepared 6 aspirin capsules containing a total of 0.56g of aspirin and 1.38g of starch as filler. The capsules were produced using a capsule molder and packaged in a bottle for storage. The student reflected on learning how to prepare capsules and highlighted that these skills will be useful for compounding medications as a future pharmacist.

    Original Description:

    manongsong preparation 3

    Original Title

    MANZANERO_Preparation 3

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    This document summarizes a student's laboratory preparation of aspirin capsules. The student prepared 6 aspirin capsules containing a total of 0.56g of aspirin and 1.38g of starch as filler. The capsules were produced using a capsule molder and packaged in a bottle for storage. The student reflected on learning how to prepare capsules and highlighted that these skills will be useful for compounding medications as a future pharmacist.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    40 views3 pages

    Spirin Capsula: Storage: Store in A

    Uploaded by

    James Azurin
    This document summarizes a student's laboratory preparation of aspirin capsules. The student prepared 6 aspirin capsules containing a total of 0.56g of aspirin and 1.38g of starch as filler. The capsules were produced using a capsule molder and packaged in a bottle for storage. The student reflected on learning how to prepare capsules and highlighted that these skills will be useful for compounding medications as a future pharmacist.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 3

    Pharmaceutical Dosage Forms, Drug Delivery Systems and Medical Devices

    Pharm 201L

    Name: Manzanero, Mckian Pius L. Group: 12


    Year/Section: BS Pharmacy Q2A Final Rating:

    Preparation No. 3
    ASPIRIN CAPSULE

    A. Wrap-Up Guide Questions:

    • Synonym/s: Aspirin capsula


    • Uses of Preparation: Analgesic & Antithrombotic
    • Method/s of Preparation used: Spatulation
    • Method/s of Administration: Oral administration
    • Packaging material/s used in the preparation: Wide mouth bottle,
    capsule molder
    • Particular Equipment (if any): Spatula, Pill Tile, Mortar and Pestle
    • Ideal temperature and storage conditions: Store at temperatures not
    exceeding 30°C. Protect from light.
    • Description of Finished Product: A white crystalline fine powder,
    enclosed in an empty gelatin capsule shell.
    B. Facsimile label:

    Each 323mg contains: Amount: 323mg Lot No: 2009S0312


    93mg……………….Aspirin Mfg Date: 09/08/2020
    230mg……………..Starch ASPIRIN Exp Date: 09/08/2022
    CORTEL
    Indication:
    Mild to moderate pain 93mg CAPSULE
    ANTITHROMBITIC
    Direction:
    Adult: Initially, 300-900 Manufactured by:
    mg, repeated 4 - 6 hourly MedCraft Pharmaceuticals
    according to clinical Storage: Store in a
    needs. UPH-DJGTMU College of place not exceeding
    Max: 4 g daily. Pharmacy 30°C.

    Formula based on preparation:


    Ingredients Quantity Physical Appearance Uses
    Aspirin 93mg x 6 = Colorless to white crystalline Reduce fever and
    0.56g solid with a vinegar odor due relieve mild to
    its hydrolysis yielding moderate pain 
    salicylic and acetic acid
    Starch 230mg x 6 = White, tasteless powder that Processing aids and
    1.38g is insoluble in cold water or additives
    alcohol.
    Pharmaceutical Dosage Forms, Drug Delivery Systems and Medical Devices
    Pharm 201L

    B. Calculation(s):
    Ingredients Original Quantities Computed Quantities

    Aspirin 0.185g 0.56g

    Starch 0.460g 1.38g

    To make 2 capsules 6 capsules

    93mg + 230mg =323mg

    Ratio & Proportion


    Aspirin Starch

    (0.185 g x 6 capsule) / 2 capsule = 0.56 g (0.460 g x 6 capsules) / 2 capsule = 1.38 g

    C. Attachment(s) of actual laboratory activity: (if any) – N/a

    D. Self-Reflection:
    • What have you learned from the activity?
    I learned how to prepare such capsules as aspirin capsule with the use of
    the capsule molder

    • Based on the discussion, what specific topic will surely be useful on


    your future chosen career?
    It will be the preparation of capsule itself through the use of ingredients
    such as starch, and with the use of the capsule molder.

    • How will this benefit you as future pharmacist?


    With the use of the learned topics, it will benefit me in the practical
    compounding of drugs in the future.
    Pharmaceutical Dosage Forms, Drug Delivery Systems and Medical Devices
    Pharm 201L

    POST-LAB QUESTIONS

    1. What are the common problems encountered during manufacturing of


    capsules?

    • Wrong size of capsule used.


    • Lumpy, misshapen or broken,
    • Surface defect or dented capsules
    • Misalignment of capsules
    • Surface defect capsules or dented capsules
    • Failure to separate
    • Incorrect weight of drugs inside the capsule
    • Wrong powder/granules used

    2. Tablet vs. Capsule: Which has the highest dissolution rate? Explain
    briefly.
    Capsules have higher dissolution rate than tablets because it can
    be absorbed in the blood stream in a few minutes while tablets would take
    longer. In a study performed by pharmacy students of the University of
    Benin, dissolution rate constants were 0.31 ± 0.02 min-1 (capsules) and
    0.20 ± 0.03 min-1 (tablets). Thus, the capsules displayed a faster
    dissolution compared with the tablets.

    3. Give the different size of a hard gelatin capsule and their


    corresponding capacity (grams).

    Size Grams
    000 0.972g
    00 0.648g
    0 0.486g
    1 0.324g
    2 0.259g
    3 0.194g
    4 0.130g
    5 0.065g

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