02 Preparation 1 and 2

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PREPARATION NO.

1: PARACETAMOL DIVIDED POWDERS Facsimile Label: Prescription Drug


PRE-LABORATORY DISCUSSION
Materials:
 Spatula
 Pill tile
 Mortar and Pestle
Formula:
Ingredients Original Amount Computed Amount
Paracetamol 3g 1.5 g
Lactose 5g 2.5 g
To make: 10 papelitos 5 papelitos

Compounding Procedure:
1. Weigh 3 g of paracetamol and 5 g of lactose accurately.
2. Triturate the two powders separately.
3. Mix the two powders by the spatulation method.
4. Place the powders on a pill tile and use the block and divide POST-LABORATORY DISCUSSION
method.
Paracetamol Divided Powders
5. Divide evenly into the required quantity.
6. Wrap in an individual white paper and put it in an appropriate  The individual dose has been packed separately and used as asn
container. analgesic and anti-pyretic.
7. Label the container.  Synonym:
o Acetaminophen pulveres
 Method/s to Prepare:
o Spatulation
o Trituration
 Type of Preparation:
o Solid dosage form
 Uses:
o Analgesic
o Anti-pyretic
Facsimile Label: Non-prescription Drug  Methods to Pulverize:
o Trituration
o Sieving
o Grinding
 Methods of Mixing:
o Trituration
o Spatulation
o Shifting
o Thumbling
 Types of Mortar and Pestle:
o Glass
 a non-porous surface
 intended for solution, suspension, and
ointments (smooth)
o Wedgewood
 a porous surface
 facilitate the comminution of crystalline solid
(rough)
o Porcelain
 used for soft, aggregates or crystals
 Types of Paper:
o Glassine
o Vegetable parchment
o Waxed
o Bond paper
 Product Description:
o should be composed in an organized way
o color/appearance, type of preparation, odor/taste, and
action after sensation/feeling/administration
o A white crystalline fine powder, odorless, and enclosed
in a white elegant paper.

PREPARATION NO. 2: COMPOUND EFFERVESCENT


POWDERS, USP
PRE-LABORATORY DISCUSSION
Materials:
 Spatula
 Pill tile Facsimile Label: Non-prescription Drug
 Mortar and Pestle
POST-LABORATORY DISCUSSION
Formula:
Compound Effervescent Powders, USP
Ingredients Original Amount Computed Amount
Sodium bicarbonate 30 g 12.5 g  to bubble as gas escapes
Potassium sodium  Synonym:
90 g 37.5 g
tartrate o pulveres effervescentes compositii
Tartaric acid 26 10.83 g  Method/s to Prepare:
To make: 12 papelitos 5 papelitos o Spatulation
o Trituration
Compounding Procedure:
 Type of Preparation:
1. Weigh all the ingredients accurately. o Solid dosage form
2. Sieve potassium sodium tartrate and sodium bicarbonate in a  Uses:
#60 sieve mesh separately. o Antacid
3. Mix the two powders by the spatulation method and divide into  Methods to Pulverize:
5 equal parts. o Trituration
4. Wrap the mixed powders in a white wax paper. o Sieving
5. Divide the tartaric acid into 5 parts and wrap in a blue paper.
o Grinding
6. Place in an appropriate container.
 Methods of Mixing:
7. Label the container.
o Trituration
o Spatulation
o Shifting
o Thumbling
 Types of Paper:
o Glassine
o Vegetable parchment
o Waxed
o Bond paper
 Product Description:
o A white amorphous powder, tasteless, odorless, and has
a bubbling effect when added to water.

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