Viste, G.B., Fontanilla, P.P., Agpasa, V.A., Tabije, N.B., Camalig, F.M. (n.d).
Efficacy Test
and Acceptability of Kakawate (Gliricidia sepium) Leaf Extract Soap Against Mange in Dogs.
Retrieved from
https://www.academia.edu/27406478/Efficacy_Test_and_Acceptability_of_Kakawate_Gliri
cidia_sepium_Leaf_Extract_Soap_Against_Mange_in_Dogs?email_work_card=title
GINER, G. O., MABAYLAN, M. M., SISON. N. J. (n.d). Evaluation of gliricidia sepium
(kakawate) leaf extract as a potential biocontrol agent against fusarium oxysporum f. Sp.
Cubense tropical race 4 in cavendish banana. Retrieved from
https://www.academia.edu/15663950/EVALUATION_OF_GLIRICIDIA_SEPIUM_KAKA
WATE_LEAF_EXTRACT_AS_A
Carandang, R.R., Buemio, K.C., Lopez, A. The Wound Healing Action of Kakawati Gel
from Gliricidia sepium (Jacques) Steudel (Family Fabaceae). IJPTP, 2015, 6(4), 2642-2649.
https://pdfs.semanticscholar.org/d0c9/de0b863f1437e2d919bc89e2469cd687b389.pdf
SAEP, M.R., DOMINO, R., ARRANGUEZ, M. (n.d) The Antifungal Property of Madre de
Cacao (Gliricidia sepium) Leaves Extract: Its Effects on Skin Diseases. Retrieved from
https://www.academia.edu/8147468/The_Antifungal_Property_of_Madre_de_Cacao_Gliric
idia_sepium_Leaves_Extract_Its_Effects_on_Skin_Diseases?email_work_card=view-paper
Dasigan, Y., Regidor, E., Tomatao, T., (n.d). The Utilization of Guava (Psidium guajava
linn.) Leaves Extract in Treating Wounds. Retrieved from
https://www.academia.edu/35877396/The_Utilization_of_Guava_Psidium_guajava_linn._L
eaves_Extract_in_Treating_Wounds
JOSE, B. & REDDY J.. (20100 EVALUATION OF ANTIBACTERIAL ACTIVITY OF
THE LEAF AND FLOWER ESSENTIAL OILS OF GLIRICIDIA SEPIUM FROM
SOUTH INDIA. Retrieved from
https://www.academia.edu/15663950/EVALUATION_OF_GLIRICIDIA_SEPIUM_KAKAWATE_LEAF_EXTRA
CT_AS_A
Díaz-de-Cerio, E., Verardo, V., Gómez-Caravaca, A., Fernández-Gutiérrez, A. and Segura-
Carretero, A. (2017) Health Effects of Psidium guajava L. Leaves:
An Overview of the Last Decade. Retrieved from
https://www.semanticscholar.org/paper/Health-Effects-of-Psidium-guajava-L.Leaves%3A-
An-of-D%C3%ADaz-de-Cerio-Verardo/523c4f9b2de55e31f81adb03aa9bffbb3d6ac4de
Rojas, J., Ochoa, V., Ocampo, S., and Muñoz, J. (2006). Screening for antimicrobial
activity of ten medicinal plants used in Colombian folkloric medicine: A possible
alternative in the treatment of non-nosocomial infections. Retrieved from
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1395329/
Fernandes, K., Bussadori, S., Marques, M., Sumie, N., Wadt, Y., Bach, E., Martins, M.
(2010). Healing and cytotoxic effects of Psidium guajava (Myrtaceae) leaf extracts.
Brazilian Journal of Oral Sciences.
9. Aim: The aims of this study were to evaluate the wound healing potential in vivo and the
cytotoxic effects in vitro of Psidium guajava (Myrtaceae) leaf extract and commonly used
corticosteroids. Methods: The healing effect was studied in vivo by the clinical and
histological evaluation of traumatic lesions in the oral mucosa of rats treated with these
substances. Each rat received 2 daily applications of the medicine tested and the animals
were sacrificed after 1, 3, 5, 7 and 14 days. Tissue sections stained with hematoxylin &
eosin were analyzed. The histological evaluation involved a 5-point scoring system based on
the degree of healing, ranging from 1 (total repair of epithelium and connective tissue) to 5
(epithelial ulcer and acute inflammatory infiltrate). The Kruskal-Wallis test was used for
statistical analysis of the histological scores. For the in vitro toxicity assay, each substance
was applied to mucosa fibroblast cell cultures in conditioned media. The media were
conditioned by placing the substances in contact with fresh culture medium for 24 h. The
cytotoxicity analysis was performed using the MTT assay. Data were analyzed statistically
by ANOVA and Tukey's test at 5% significance level. Results: In vitro, the guava extract
caused a decrease in the cell viability and growth when compared to the control and
corticosteroids. In vivo, guava extract caused accelerated wound healing from the 3rd day,
whereas the corticosteroids delayed tissue repair and were associated with bacterial surface
colonization, the presence of micro-abscesses and intense inflammatory infiltrate in the
submucosa. Conclusions: Although in a short-term cytotoxicity analysis, the guava extract
reduced the cell population in vitro, while in vivo, the extract accelerated wound healing.
Mallapu, P. (2017). MEDICINAL PROPERTIES OF Gliricidia sepium: A REVIEW.
International Journal of Current Pharmaceutical & Clinical Research. 7. 35-39.
Therapy with medicinal plants is as old as mankind itself. Awareness of medicinal plants
usage is a result of many years of struggles next to illnesses due to which man learned to
pursue drugs from bark, seeds, fruits, and other parts of the plants. Contemporary science
has accredited their active action, and it has included in modern pharmacotherapy a range
of drugs of plant origin, known by ancient civilizations and used throughout the millennia.
The knowledge of the improvement of ideas related to the usage of medicinal plants as well
as the development of awareness helps to increase the ability of pharmacists and physicians
to respond to the challenges that have emerged with the spreading of professional services
in facilitation of man's life.
Practices in Wound Healing Studies of
Rupesh Thakur, etal. (2011).
Plants. Retrived from https://doi.org/10.1155/2011/438056
