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APRIL HOME ASSIGNMENT

ASSIGNMENT # 1
SUBJECT: BIOLOGY
TIMING: 01 hour
MARKS: 30
SUBMISSION DEADLINE: 18th April’ 2020

Instructions for Students:

1. Kindly write the following details at the beginning of each answer sheet:
i. Name of Student
ii. School Student ID#
iii. Subject
iv. Name of Subject Teacher
v. Assignment #
vi. In case there is a choice given in the assignment write the Question # you have
attempted.

2. A total of two assignments are required for each subject.

3. Assignment received after the submission date given above will not be graded.

4. The assignment should be completed within the suggested time.

5. Students should note that they must submit original work. These assignments will be checked
for plagiarism through software.

6. How to submit the assignment?

i. Assignment should be neatly handwritten on any lined paper
ii. Download a Cam Scanner on your phone from app store or play store
iii. Scan your assignment answer sheet
iv. Convert it to pdf format
v. Upload the answer sheet only on Google Classroom. (In case you are unable to upload it
on your Google Classroom share it with your teacher on his/her email address).

This question paper consists of 15 printed pages.

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1. Actual length of a cell structure is 5 um.

State an equation to calculate the magnification of an electron micrograph of this cell structure.
You can use letters q to u in the equation.

q = the length of the image of the cell structure on the micrograph in centimetres

r = the length of the image of the cell structure on the micrograph in millimetres

s = 1000

t = 1/5

u=5

Which is the correct equation to calculate the magnification?

A q/sxu B qxsxt C r/sxu D rxsxt

2 Which features shown in the diagram can be present in eukaryotes?

A 1, 2 and 3 B 1, 2 and 4 C 1, 3 and 4 D 2, 3 and

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3 The diagram shows an eyepiece graticule and part of a stage micrometer scale as seen using

x 100 magnification.

How is the value, in um, of one eye piece graticule unit calculated?

A divide 100 by 0.1 and multiply by 1000

B divide 100 by 0.1 and multiply by 1000 divided by 100

C multiply 0.1by 1000 and divide by 100

D multiply 0.1 by 1000 and divide by 100 , then divide again by 100

4 A student carried out a benedict test on several different concentrations of alpha glucose.
Which graph represents the results correctly?
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5 Fibrous proteins are composed of chains of amino acids held together by bonds.
An example of a part of a fibrous protein is shown.

Which type of bond is at X and Y ?

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6. Test for biological molecules were carried out on food samples.

Which of the following correctly matches the biological molecules in the food samples with the
colour for a positive result?

7 Three proteins that have a quaternary structure are listed.

. Type IX collagen is formed from three different polymers

. The main form of haemoglobin contains two alpha globins and two beta globins

. HIV protease consists two identical polymers

Which row shows the correct number of genes needed to code for each type of proteins?
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8 Some extracellular protease enzymes are synthesized in an inactive form called zymogen.
Zymogen is converted to the active protease in the Golgi body .

What is the purpose of producing zymogen before converting it to the extracellular protease?

A to avoid unwanted digestion of proteins inside the cell

B to avoid unwanted digestion of proteins outside the cell

C to catalyse digestion of proteins in the cytoplasm

D to catalyse digestion of proteins in the rough endoplasmic reticulum

9 An experiment was carried out to compare the effect of pH on the activity of an enzyme
That was in solution and the same enzyme that had been immobilized on a gel.

All other variables were kept the same.

The results are shown in the graph.

Which statement explains these results when the enzyme is immobilized?

A The primary structure has changed

B The secondary structure has changed

C The tertiary structure has changed

D The quaternary structure has changed

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10 The Michaelis –Menten constant for an enzyme catalysed reaction is referred to as Km, and
the maximum velocity of such a reaction is known as Vmax.

Which statement about Km and Vmax is correct?

A an enzyme with a high value of Km can reach its Vmax at a low substrate concentration
B an enzyme with a high value of Km has a high affinity to its substrate

C an enzyme with a low value of Km can reach its Vmax at high substrate concentration
D an enzyme with a low value of Km has a high affinity to its substrate

11 The diagram represents a cell surface membrane of a metabolically active cell and the
direction of movement of some molecules through the membrane.

Which row shows a process by which the molecules may be moving through the membrane
at each of the points 1, 2, 3 and 4?
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12 High concentrations of ethanol can disrupt cell membrane structure and make the cell surface
membrane leaky. Yeast cells release ethanol as a waste product of metabolism.

Yeast cells can alter the composition of the cell surface membrane to reduce the effect of
ethanol.

. A saturated fatty acid , X, is replaced by an unsaturated fatty acid, Y.

. Y has a shorter hydrocarbon chain than X.

. There is an increase in the phospholipid to protein ratio Which

statement would explain why the effect of ethanol is reduced?

A A greater proportion of phospholipid may increase the entry of ethanol via channel proteins

B An increase in hydrophobic interactions by phospholipid tails improves membrane stability

C An increase in the proportion of fatty acids with double bonds decreases membrane fluidity

D The shorter hydrocarbon chain of Y decreases membrane fluidity.

13 The diagram shows a simple cell cell signaling pathway in which a signal molecule leads to a
response, such as secretion.

Signal molecule___________ P ___________ Q __________ Response

Which row identifies P and Q?

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14 Three parts of a chromosomes and there functions are listed.

Which part is matched with its correct function?

A P 1 and F 2 B P 2 and F 2 C P 2 and F 3 D P 3 and F 2

15 What correctly describes the effect of carcinogens on lung tissue that causes a tumour to
Develop?

A Cells in damaged alveoli walls divide more rapidly to replace damaged areas.

B Cilia are paralysed and mucus accumulates in the lungs causing DNA to damage.

C DNA changes, causing bronchial epithelial cells to divide by mitosis in an uncontrolled way.
D Haemoglobin carries less oxygen causing bronchial cells to divide by mitosis in an

uncontrolled way.

16 The diagram shows part of a DNA sequence of a gene and a mutated sequence of the
same gene.

Normal DNA sequence …… CCG GAT TAT TGC GAG AAA TGG CAT TCT AGG……
Mutated DNA sequence…… CCG GAT GTA TTG CGA GAA ATG CAT TCT AGG…..

What are the possible effects of themutated sequence?

1. the presence of mRNA stop codons, UAG UAA UGA

2. a change in the sequence of amino acids
3. a non functional protein
4. ribosomes cannot translate the mRNA

A 1, 2 and 3 B 1, 3 and 4 C 1 and 4 D 2 and 3

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17 Meselson and Stahl investigatedDNA in bacteria. They grew bacteria in a medium with only
Heavy nitrogen, N 15 until all of the bacterial DNA was heavy.

Those bacteria were moved from a heavy nitrogen medium and cultured in a medium with
only light nitrogen, N 14.

A sample of bacteria was collected from the first generation and their DNA analysed.
Hybrid DNA contains heavy DNA and light DNA.

Which row shows the percentage of light DNA strands and the percentage of hybrid DNA
molecules in this first generation produced in the medium containing light nitrogen?

18 Four plants, A, B, C and D, were grown in the same conditions and their transpiration rates
measured.

Which plant is most likely to be a xerophyte?

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19 The diagrams show transverse sections of parts of a plant with some transport tissues
labelled 1-6.

Which tissues mainly transport water, and which tissue mainly transport sucrose?
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20 When sucrose is loaded into the phloam it has to travel from mesophyll cells to a companion
cell And then into the phloem.

In many plants proton pumps, and co-transporter molecules are involved in this process.

21 The statements list some of the events in the cardiac cycle. They are not in the correct order.

Which statement describes the fifth of these events to occur in the cardiac cycle?

1 The impulse travels through purkyne tissue.

2 A wave of excitation sweeps across the atria.
3 The atrioventricular node delays the impulse for a fraction of a second.
4 The sino atrial node contracts
5 The wave of excitation sweeps upwards from the base of the ventricles.
6 The ventricles contract.
7 The atria contract.

A1 B3 C4 D 7

22 If the left atrioventricular valve in the heart does not close completely it results in blood flowing
Back into the atrium during ventricular systole.

What would be the immediate effect ofthis backflow?

A Blood flowing from the heart carries less oxygen because less blood enters the lungs. B
Diastolic pressure in left ventricle falls because less blood enters the pulmonary artery. C
Lower systolic pressure in the left atrium and less blood enters the pulmonary artery.

D Raised pressure in the left atrium and less blood enters the aorta.
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23 The diagram below shows some of the reactions of carbon dioxide when it enters the blood
from Cells in a metabolically active tissue.

Which reaction is catalysed bythe enzyme carbonic anhydrase?

24 The surface tension of the layer of liquid lining the alveoli tends to pull the walls inwards so alveoli
Could collapse.

Which statements could explain how this is prevented?

1 Alveolar fluid is moved around by cilia.

2 Elastic fibres keep the alveoli open.
3 Epithelial cells secrete achemical that reduces the cohesion in water.

A 1 and 2 B 1 and 3 C 2 and 3 D 3 only

25 Some symptoms of chronic obstructive pulmonary disease [ COPD] are listed.

1 bursting of alveoli
2 loss of elastic fibres
3 increase in secrtion of mucous
4 reduction in surface area for gas exchange
5 narrowing of airways

Which of these are also symptoms of emhysema?

A 1, 2 and 4 B 1, 3 and 5 C 2, 3 and 5 D 3, 4 and 5

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26 The statements refer to the disease tuberculosis (TB).

1 The pathogen lives inside human cells so is not accessible to the immune system
2 The bacterial pathogen reproduces slowly.
3 The pathogen is not very sensitive to antibiotics.

Which of the following explains why antibiotic treatment for TB takes a long time?

A 1, 2 and 3 B 1 and 2 only C 1 only D 2 and 3 only.

27 Which factors contribute to outbreak of measle after natural disasters?

1 Contamination of drinking water with untreated sewage.

2 Lack of effective vaccination coverage in the population before the disaster
3 People living in overcrowded accommodation

A 1, 2 and 3 B 1 and 2 only C 1 and 3 only D 2 and 3 only

28 Immune response to a vaccination against a virus can be assessed by making

three measurements.

1 the concenation of anti-virus antibody in the blood.

2 The time taken to increase the antibody concentration significantly after a
booster vaccination.
3 Th cellse number of virus specific lymphocytes per ml blood

What describes the immunity of an individual when the values of 1, 2 and 3 are all low

ten years after vaccination?

A active immunity due to the presence of memory cells.

B low immunity due to absence of antibodies.

C low immunity due to absence of memory cells

D passive immunity due to pesence of antibodies

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29 Which statements describe myasthenia gravis?

1 Antibodies attack proteins within the body.

2 T- lymphocytes are involved in an inflammatory response.
3 The immune system blocks receotors at neuromuscular junction.
4 The immune system attacks the central nervous system.

A 1 and 3 B 1 and 4 C 2 and 3 D 2 and 4 I

30 Which features of monoclonal antibodies make them useful in the diagnosis and treatment

of disease?

1 a particular monoclonal antibody attaches to a specific antigen.

2 Identical monoclonal antibodies can be produced in large numbers.
3 Binding a monoclonal anibody to its specific antigen may mark that antigen
for destruction by white blood cells
4 Flourescent or radioactive markers can be attached to a monoclonal antibody to show
where the antigen is in the body.
A 1, 2, 3 and 4

B 1, 2 and 3

C 2 and 3

D 3 and 4
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