Santiago, Gwyneth Julia B.-Bsn2-D-Drug Study

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SANTIAGO, GWYNETH JULIA B.

BSN 2-D
DRUG STUDY

NAME OF THE MECHANISM OF DOSAGE INDICATIONS CONTRA- ADVERSE NURSING ALERT


DRUG ACTION INDICATIONS REACTION
Generic name: Erythromycin is a Dosage: Infections caused - Contraindicated CNS: seizures (rare). History: Allergy to erythromycin,
bacteriostatic antibiotic, by susceptible in: Hypersensitivity; EENT: ototoxicity. hepatic impairment, lactation;
Eryhtromycin which means it prevents 250mg organisms including: Concurrent use of CV: TORSADE DE viral, fungal, , pregnancy
the further growth of up to 4 g/day, Upper and lower pimozide, POINTES, Physical: Site of infection; skin
bacteria rather than depending on respiratory tract ergotamine, VENTRICULAR color, lesions; orientation, affect,
directly destroying it. the severity of infections, Otitis dihydroergotamine, ARRHYTHMIAS, QT hearing tests; R, adventitious
Once erythromycin is the infection media (with procainamide, interval prolongation. sounds; GI output, bowel sounds,
Brand name: orally administered, it sulfonamides), Skin quinidine, dofetilide, GI: liver evaluation; culture and
gets deactivated by and skin structure amiodarone, or PSEUDOMEMBRANOU sensitivity tests of infection,
Erythrocin gastric acid. Oral tablets infections, Pertussis, sotalol; Long QT S COLITIS, nausea, urinalysis, LFTs.
must either contain an Frequency: Diphtheria, syndrome; vomiting, abdominal  Culture site of infection before
ester or stable salt as part Erythrasma, Hypokalemia; pain, cramping, therapy.
of the molecular structure q6h PO Intestinal amebiasis, Hypomagnesemia; diarrhea, hepatitis,  Administer oral erythromycin
or be enteric-coated. The Pelvic inflammatory Heart rate 50 bpm; infantile hypertrophic base or stearate on an empty
liver metabolizes most of disease, Known alcohol pyloric stenosis, stomach, 1 hr before or 2–3 hr
the administered Nongonococcal intolerance (most pancreatitis (rare). after meals, with a full glass of
erythromycin. It Classification: urethritis, Syphilis, topicals); Tartrazine GU: interstitial water (oral erythromycin
undergoes demethylation Legionnaires’ sensitivity (some nephritis.Derm: rash. estolate, ethylsuccinate, and
through the cytochrome Macrolide disease, Rheumatic products contain Local: phlebitisat IV certain enteric-coated tablets
P450 system, specifically antibiotics fever. tartrazine— FDC site. [see manufacturer’s
the enzyme CYP3A4, and yellow dye #5); Misc: allergic instructions] may be given
undergoes Products containing reactions, without regard to meals).
elimination through bile. benzyl alcohol superinfection.  Administer around the clock to
A very small percentage should be avoided in maximize effect; adjust
of the drug undergoes neonates. schedule to minimize sleep
renal excretion. - Use Cautiously disruption.
Erythromycin has a in: Liver/renal  Monitor liver function in
half-life of 1.5 to 2 hours. disease; OB: May be patients on prolonged therapy.
Levels of the drug peak 4 used in pregnancy to  Give some preparations
hours after intake. treat chlamydial with meals, as directed, or
infections or substitute one of these
syphilis. preparations, if GI upset
occurs with oral therapy.
SANTIAGO, GWYNETH JULIA B. BSN 2-D

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