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Continous Flow Analyzer

Continuous Flow Analysis (CFA) is a technique that allows for the simultaneous determination of up to 12 analytical methods on a single instrument. It provides high sample throughput, reproducible mixing of reagents, and the ability to automate complex sample preparation procedures. Some key advantages of CFA include unbeatable analysis capacity, quality diagnosis through segmented flow, low running costs using standard reagents, and the ability to apply numerous approved analytical methods.

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Goh Mun Hon
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320 views2 pages

Continous Flow Analyzer

Continuous Flow Analysis (CFA) is a technique that allows for the simultaneous determination of up to 12 analytical methods on a single instrument. It provides high sample throughput, reproducible mixing of reagents, and the ability to automate complex sample preparation procedures. Some key advantages of CFA include unbeatable analysis capacity, quality diagnosis through segmented flow, low running costs using standard reagents, and the ability to apply numerous approved analytical methods.

Uploaded by

Goh Mun Hon
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PDF, TXT or read online on Scribd
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Technique Concept, Application Specific Advantages

CFA • Specific method on • Unbeatable analysis capacity by simultane-


each analysis manifold ous determination of all applicated methods
• typical 3-4 module / • Unique possibility of quality diagnosis, re-
methods sulting from the use of the segmented flow
• Expandable up to 12 technique
simultaneous analytical• High intensity, high repeatable mixing of re-
methods action solutions in each stages of the auto-
mated procedure
• Usually applied for
• Complicated and individual sample prepara-
higher sample through-
tion and reaction procedures can be applied
put and limited number
on the analytic manifold
of methods to be auto-
• Outstanding small running costs, using stan-
matized
dard laboratory reagents
• Countless number of available and approved
methods, resulting from world-wide use of
CFA over decades

Continuous-Flow Analysis (CFA)


CFA is also known as Segmented Flow Analysis (SFA), to outline against FIA
technique. Existing ISO standards define: "Methods using flow analysis are auto-
matizing wet chemical procedures and are therefore particularly suitable for proc-
essing large sample series... One differentiates between flow injection analysis
(FIA) and continuous flow analysis (CFA)."

Continuous Flow Analysis is the traditional technique. We give favour to CFA as it


provides valuable advantages for the practical routine work in typical fields of flow
analysis application.

How works CFA Analysers ?

Each sample or calibrant, taken on the


autosampler, is splitted to flow into the
different manifolds for simultaneous
determination.

The aspiration of the next following


sample after 60 seconds gives an
analysis frequency of 60 samples per
hour. A sequence of 90 seconds will result in 40 samples per hour throughput.
The aspiration of blank water in between is included in this interval.
The number of samples/h multiplied by the number of simultaneous determina-
tions gives the number of analysis per
hour on the CFA analyser.

The segmentation of the CFA assures


best separation between successive
samples, also for time consuming prepa-
ration steps on the analyser or after long
delay for slow reactions. Consequently
CFA provides better safety against any
memory effect.

Today's newcomers in the application of


Segmented
Flow technique in most cases justify their decision
upon the efficiency of integrated sample preparation
procedures. The time savings from the omission of
manual digestion of organic P or N compounds, of
manual distillation for Cyanide, Phenolindex or Fluo-
ride guarantees the profitability of investment.

Well experienced us-


ers of CFA on the other hand purchase new ana-
lysers to renew their instrumentation after a work-
ing life of 15 years or more.

The PC based system control and data handling


applies specific user-friendly software, comprising
over 20 years of experience in CFA data handling,
along several operating systems. Consider, that
automatically documentation of original analysis data, integrated QM procedures
and computerised calculation and reporting results in additional time savings
against manual analysis procedures.

Technical Data of a CFA Analyser:

• Segmented flow techniques Macroflow or Microflow


• Autosampler serial 52/104 positions or XY sampler 240 (300) positions
• Multichannel proportioning pump with 12/48 positions, segmentation by air or N2
• Individual method 'manifolds' for dilution, mixing, incubation, dialysis, distillation,
UV digestion, hydrolysis, a.o.)
• Individual filter colorimeter for each analysis manifold, mono or bichromatic
• Flowcell 10-50 mm ligthpath, debubbling or bubble gating
• Sophisticated electronics for colorimeter and system control
• PC station with CFM software and printer

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