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    Formulation and Evaluation of Anisomeles Malabarica Panchang Kshara

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    yogesh ushir
    This document summarizes the formulation and evaluation of Anisomeles Malabarica Panchanga Kshara. Key points: - The study prepared Anisomeles Malabarica panchanga Kshara under standard laboratory conditions and evaluated its organoleptic and qualitative characteristics for the first time. - Phytochemical parameters revealed presence of metabolites like amino acids, flavonoids, tannins, terpenoids. - Thin layer chromatography identified Rf values of extracts. Ash value was 10.63% w/w. - The kshara obtained meets quality standards and can be used similarly to other ksharas for disorders like renal calculi, hemorrhoids,

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    Formulation and Evaluation of Anisomeles Malabarica Panchang Kshara

    Uploaded by

    yogesh ushir
    61 views4 pages
    This document summarizes the formulation and evaluation of Anisomeles Malabarica Panchanga Kshara. Key points: - The study prepared Anisomeles Malabarica panchanga Kshara under standard laboratory conditions and evaluated its organoleptic and qualitative characteristics for the first time. - Phytochemical parameters revealed presence of metabolites like amino acids, flavonoids, tannins, terpenoids. - Thin layer chromatography identified Rf values of extracts. Ash value was 10.63% w/w. - The kshara obtained meets quality standards and can be used similarly to other ksharas for disorders like renal calculi, hemorrhoids,

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    International Journal of PharmaO2

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    This document summarizes the formulation and evaluation of Anisomeles Malabarica Panchanga Kshara. Key points: - The study prepared Anisomeles Malabarica panchanga Kshara under standard laboratory conditions and evaluated its organoleptic and qualitative characteristics for the first time. - Phytochemical parameters revealed presence of metabolites like amino acids, flavonoids, tannins, terpenoids. - Thin layer chromatography identified Rf values of extracts. Ash value was 10.63% w/w. - The kshara obtained meets quality standards and can be used similarly to other ksharas for disorders like renal calculi, hemorrhoids,

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    61 views4 pages

    Formulation and Evaluation of Anisomeles Malabarica Panchang Kshara

    Uploaded by

    yogesh ushir
    This document summarizes the formulation and evaluation of Anisomeles Malabarica Panchanga Kshara. Key points: - The study prepared Anisomeles Malabarica panchanga Kshara under standard laboratory conditions and evaluated its organoleptic and qualitative characteristics for the first time. - Phytochemical parameters revealed presence of metabolites like amino acids, flavonoids, tannins, terpenoids. - Thin layer chromatography identified Rf values of extracts. Ash value was 10.63% w/w. - The kshara obtained meets quality standards and can be used similarly to other ksharas for disorders like renal calculi, hemorrhoids,

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
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    of 4

    Vol.2/Issue2/Mar-Apr 2020 Inter. J.

    Pharma O2 ISSN: 2582-4708

    International Journal of PharmaO2


    Journal Home Page: http://www.ijpo.in/
    (IJPO: A Peer-reviewed Bi-monthly online journal)

    Formulation and Evaluation of Anisomeles Malabarica


    Panchanga Kshara
    Bhagyashri D. Nagare*
    Research Scholar, Atal Bihari Vajpayee Homeopathic Medical College and Hospital, Aurangabad-
    Ahmednagar-Pune Hwy, Jalke Bk, Maharashtra 414603, India.

    Abstract
    Ksaras are the derivatives of plant drug ashes in the form of solutions or crystals all of which have the
    basic quality of being alkaline. Because of its corrosive nature (Ksaranat), it is known as Kshara
    (alkali), Kshara is not having rasa, this is manifested by the combination of many rasas and it
    possesses itself many rasas dominated by katu and lavana rasas. It is the object of many senses and it
    involves a special method of preparation. In the present study, we have prepared Anisomeles
    malabarica panchanga Kshara under standard laboratory conditions and studied about the organoleptic
    and qualitative characteristics of Anisomeles malabarica Kshara. The Phytochemical parameters for
    the Anisomeles malabarica panchanga were also studied with the aim of drawing the phytochemical
    standards for this species. The presence study includes phytochemical standardization of Anisomeles
    malabarica aerial parts first time. The presence study includes preparation and evaluation of
    Anisomeles malabarica kshara first time.
    Keywords: Ksaras, Anisomeles malabarica, Rasas, Panchanga, Standardization.
    Corresponding author: Ms. Bhagyashri D. Nagare, email:[email protected]

    Introduction rats and acetylcholine antagonistic activity in


    Anisomeles malabarica is a medicinal plant, frog skeletal muscle contraction, also have
    slightly aromatic subshrub commonly seen in antioxidant activity (Kavimani S. et al., 1998;
    India, It is grown in Hills above 600m on the Sundarammal S et al, 2012).
    slopes, in crevices of rocks; more numerous by As per our knowledge there is no
    arable lands, etc. It have a number of phytochemical study carried on aerial parts of
    pharmacological uses as, aqueous extract of the Anisomeles malabarica. Therefore we
    leaves is reported to have diuretic activity in

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    Vol.2/Issue2/Mar-Apr 2020 Inter. J. Pharma O2 ISSN: 2582-4708

    focused our study on the phytochemistry of Thin layer chromatography of the ethanolic
    Anisomeles malabarica. extract was studied and Rf values were
    As the plant is very potential in determined (Harborne JB., 1985; Brain KR,
    pharmacological uses the hypothesis were Turner TD., 1975).
    made that its Kshara preparation may prepared Preparation of Kshara
    and evaluated. As ksara preparation rich in The Anisomeles malabarica kshara prepared as
    inorganic elements and it may use as diuretic, per general procedure mentioned for kshara in
    electrolyte replenisher etc. the aim draws in Bhaisajya Kalpana Vijnanam (Dr. G.
    this study ‘preparation and evaluation of Prabhakara Rao, 2008). The dried whole plant
    Anisomeles malabarica panchang kshara’. of Anisomeles malabarica powdered. Burn to
    Materials and Methods ash (Bhasma). Add 4 parts of water to the
    Procurement of plant material Bhasma stir well and keep overnight. Next
    Fresh panchang (leaf, flower, stem, root, bark) morning decant the clear liquid and filter
    of Anisomeles malabarica was supplied by Mr. through a three-layered muslin cloth. Repeat
    D. Md. S. Sheikh, Proprietor of Sheikh the filtering process till a colorless filtrate is
    International, Dindigul, State-Tamilnadu, obtained. Transfer filtered material to a
    India, in the month of February 2019. stainless steel vessel and heat to evaporate the
    Botanical identification of plant was water. Collect kshara deposited as flakes from
    authenticated by Asso. Prof. Rajesh T. the bottom of the vessel and grind it to a fine
    Wankhade, Dept. of Dravyguna, S.M.B.T. powder. Pack it in tightly closed containers to
    Ayurvedic College and Hospital, Nashik. protect from light and moisture (Anonymous,
    Phytochemical Study 2019).
    The successive extractive values carry out as Results and Discussion
    per the procedure of C. K. Kokate (Kokate The moisture content seems to be lower than
    CK., 1994). Physical Evaluation-Moisture necessary to support the growth of microbes to
    content of the powdered determined based on bring any change in the composition of the
    the loss of drying method (Khandelwal KR., drugs. Physical constant as ash value of the
    2005). The ash values were determined, to find drug gives an idea of the earthy matter or the
    out about the physiological state and level of inorganic composition and other impurities
    extraneous matter. Extractive values were present along with the drug. Extractive values
    determined according to the official methods are useful for the determination of exhausted or
    prescribed in Ayurvedic Pharmacopoeia adulterated drugs. The Phytochemical
    (Anonymous, 1985). TLC Finger Print Profile- Investigation revealed the presence of

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    Vol.2/Issue2/Mar-Apr 2020 Inter. J. Pharma O2 ISSN: 2582-4708

    metabolites as amino acids, flavonoids, Inorganic Elements Inference


    Calcium --
    tannins, terpenoids, keto steroids, phenols and
    Magnesium --
    carbohydrates. Thin layer chromatography of Sodium ++
    Potassium ++
    the ethanolic extracts was carried out using
    Iron ++
    Ethanol: Ethyl acetate (6:4) as mobile phase, Sulphate ++
    Phosphates --
    silica gel GF254 as stationary phase and the Rf
    Chloride ++
    were recorded as 0.15, 0.19, 0.23, 0.73 and Carbonates ++
    Nitrates --
    0.93. The total Ash Value was found to be
    ++ presence; -- absent
    10.63 w/w (Table 1).
    Conclusion
    Table 1: Physical Evaluation of Anisomeles
    The internal use of Kshara is advised in
    malabarica Panchang
    Mutrashmari (viz. renal calculi), external
    Parameter % w/w
    application in Arshas (hemorrhoid piles) and in
    Ash Values
    Total 10.63+0.545 the form of Kshara Sutra in the treatment of
    Acid - insoluble 02.56+0.160
    Bhagandhara (fistula-in-ano) (Shruti Pandey et
    Water – soluble 06.46+0.155
    Extractive Values al., 2016).
    Pet. Ether Soluble (40-60o) 04.13+0.176
    So we can conclude that the Anisomeles
    Ethanol Soluble (95%) 11.57+0.761
    Water Soluble 12.78+1.106 malabarica panchanga kshara also used in
    Moisture content 08.74+0.546
    above stated diseses and disorder as it
    During study 500gm panchang powder of
    evaluated as per the modern parameter and it
    Anisomeles malabarica were take which gave
    meets the quality of available ksharas in
    53.15g of ash (Bhasma). And from that ash
    market.
    (Bhasma) finally 7.52g Anisomeles malabarica
    Acknowledgement
    panchang kshara obtained. The 10% solution
    The author are thankful to Dr. Yogesh V.
    has the pH value 10.8 which is alkaline. The
    Ushir; Principal of SMBT Institute of D.
    formulation is fine powder, passing smoothly
    Pharmacy, Dhamangaon (Nashik; India) for his
    through sieve number 100, hygroscopic, odor
    valuable support during completion of work..
    faint and taste saline, freely soluble in water.
    Funding
    The qualitatative Investigation revealed the
    There was no funding in this work.
    presence of elements as sodium (Na2+),
    Conflict of interest
    Potassium (K+), Iron (Fe2+), Sulphates (So4) etc
    The authors declare no conflict of interest.
    (Table 2).
    Reference(s)
    Table 2: Qualitative Evaluation of
    1. Kavimani S. et al. The effect of aqueous
    Anisomeles malabarica Panchang Kshara
    extract of Anisomeles malabarica on isolated
    http://www.ijpo.in Page 0149
    Vol.2/Issue2/Mar-Apr 2020 Inter. J. Pharma O2 ISSN: 2582-4708

    skeletal muscles, Ancient Science of Life, Vol. 10. Shruti Pandey, Vinamra Sharma, Anand
    No 18(1), July 1998: 1-3. Kumar Chaudhary. A Critical Review on
    2. Sundarammal S et al. Chemical composition Historical Aspects of Kshara. Int. J. Res.
    analysis and antioxidant activity evaluation of Ayurveda Pharm., Vol 7(Suppl 3), Jul - Aug
    essential oil from Anisomeles malabarica 2016: 64-69.
    (Roth) Sleesen. Asian Pacific Journal of
    Tropical Biomedicine, 2012: S112-S115.
    3. Kokate CK. Handbook of Practical
    Pharmacognosy. Vallabh Prakashan, New
    Delhi, Edition 4, 1994: 058-136.
    4. Khandelwal KR. Practical Pharmacognosy
    techniques and experiments. Nirali Prakashan,
    Pune, Edition 13, 2005:130-149.
    5. Anonymous, The Ayurvedic Pharmacopoeia
    of India. Government of India, Ministry of
    Health and Family Welfare, Controller of
    Publication, New Delhi, Part-I, Vol. I, 1985:
    24-28, 143-44.
    6. Harborne JB. Phytochemical methods.
    Chapman and Hall, London, Edition 3, 1984:
    88, 203.
    7. Brain KR, Turner TD. The practical
    Evaluation of Phytopharmaceuticals. Wright-
    Scientechnica, Bristol, 1975:81 -86.
    8. Dr. G. Prabhakara Rao. A text book of
    Bhaisajya Kalpana Vijnanam. Chaukhambha
    Publications, New Delhi, 1st ed., 2008: 180-
    182.
    9. Anonymous,
    http://www.bimbima.com/health/post/2015/11/
    27/apamarga-kshara.aspx; retrieved on
    14.10.2019.

    http://www.ijpo.in Page 0150

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