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Drug Study RLE

This document summarizes information about two drugs: Cefuroxime and Hyoscine Butylbromide. Cefuroxime is a second-generation cephalosporin antibiotic used to treat infections caused by streptococcus, haemophilus influenzae, staphylococcus aureus and E. coli. It works by inhibiting cell wall synthesis. Common side effects include diarrhea, rash and superinfections. Nurses should monitor for side effects and notify the prescriber of any issues. Hyoscine Butylbromide is an antispasmodic used to relieve smooth muscle spasms. It works by competitively blocking acetylcholine receptors. Potential side effects include dry

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Genierose Yanto
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0% found this document useful (0 votes)
127 views8 pages

Drug Study RLE

This document summarizes information about two drugs: Cefuroxime and Hyoscine Butylbromide. Cefuroxime is a second-generation cephalosporin antibiotic used to treat infections caused by streptococcus, haemophilus influenzae, staphylococcus aureus and E. coli. It works by inhibiting cell wall synthesis. Common side effects include diarrhea, rash and superinfections. Nurses should monitor for side effects and notify the prescriber of any issues. Hyoscine Butylbromide is an antispasmodic used to relieve smooth muscle spasms. It works by competitively blocking acetylcholine receptors. Potential side effects include dry

Uploaded by

Genierose Yanto
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© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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DRUG STUDY

Submitted by :
Genierose F. Yanto
BSN 2A
Patient: B. Santos Age: 44

Date admitted: 3/2/20. Time admitted: 1:45 pm

Name Mechanism of Indication/Contraindication Side Effects Nursing Responsibility


Action
Generic Second- Indication: Body as Whole:  Determine history of
Name: generation Pharyngitis, tonsillitis, infection Thrombophlebitis (IV hypersensitivity
CEFUROXIME cephalosporin of the urinary and lower site); pain, burning, reactions to
that inhibits cell respiratory tracts, and skin and cellulitis (IM site); cephalosphorins,
Brand Name: wall synthesis, skin-structure infections superinfection, positive penicillin and history of
ZOLTAX promoting caused by Streptococcus Coombs’ test. allergies particularly to
osmotic pneumonia and S. pyogenes, drugs before therapy is
Classification: instability; usually Haemophillus influenza, GI: initiated.
ANTIBIOTIC bactericidal. Staphylococcus aureus, E. Diarrhea, nausea,  Report onset of loose
coli. antibiotic-associated stool
Frequency: colitis.  Absorption of
BID Contraindication: cefuroxime is enhanced
 Contraindicated in Skin: by food
Dosage: patients hypersensitive Rash, pruritis, urticaria  Notify prescriber about
1 tab 500 mg to drug. rashes or super
 Use cautiously in Urogenital: infections
Route: patients hypersensitive Increased serum
PO to penicillin because of cretonne and BUN,
possibility of cross decreased creatinine
sensitivity with other clearance.
betalactam antibiotics.
 Use with caution in
breast feeding women
and in patients with
history of colitis or renal
sufficiency.
NAME OF MECHANISM OF NURSING
USE OF DRUG SIDE EFFECTS
DRUG ACTION CONSIDERATIONS
CLASSIFICATION: Hyoscine Butylbromide is  dryness of the mouth,  Be alert for adverse
 antispasmodic a quaternary ammonium with difficulty in reactions and drug
antimuscarinic agent. swallowing interactions.
INDICATION: Hyoscine butylbromide  thirst  Assess for eye pain
 relief of smooth does not readily pass the  dilation of the pupils with  Assess for urinary
muscle spasm of the blood-brain barrier. It’s a loss of accommodation hesitancy
gastrointestinal and competitive antagonist of and photophobia  Assess for constipation
genitourinary systems the actions of  increased intra-ocular  Monitor urine output
acetylcholine and other pressure  Encourage patient to void.
CONTRAINDICATIONS muscarinic agonists. The  flushing and dryness of  Monitor BP for possible
: receptors affected are the skin hypertension.
 Hypersensitivity to those of peripheral  bradycardia followed by
Hyoscine  For pregnant women,
hyoscine butylbromide structures that are either tachycardia, with
Butylbromide monitor cervical effacement
 Porphyria stimulated or inhibited by palpitations and
20mg 1 amp and dilatation.
 Myasthenia gravis muscarine, ie. exocrine arrhythmias
IV glands, smooth and
 Prostatic enlargement,  urinary urgency with the
paralytic ileus or cardiac muscle.
inability to do so, as well
pyloric stenosis and as reduction in the tone
fever and motility of the gastro-
 Closed angle intestinal tract, leading to
glaucoma, or narrow constipation
angle between the iris  occasionally vomiting,
and cornea, as giddiness and staggering
hyoscine increases may occur
intra-ocular pressure  restrosternal pain may
 pregnant and lactating occur due to increased
mothers gastric reflux.
DRUG CONTRAINDIC ADVERSE NURSING
DRUG INDICATION ACTION
INTERACTION ATION EFFECT CONSIDERATION
Generic Name: Short-term treatment of Gastric acid- Omeprazole Contraindicated
omeprazole activeduodenal ulcer; pumpinhibitor:Su potentially can with Diarrhea, nausea, Caution patient
First-linetherapy in ppresses increase the  hypersensitivit fatigue, toswallow capsules
treatment of heartburn gastricacidsecreti concentrations in blood y to constipation, whole—not to open,
or symptoms onby omeprazoleor vomiting, chew, or crush
of diazepam (Valium), 
of gastroesophageal specificinhibition its flatulence, acid them.Arrange for
Brand Name: warfarin (Coumadin),
refluxdisease (GERD); of thehydrogen- components;Us regurgitation, further evaluation of
Prilosec Short-termtreatment of potassiumATPas andphenytoin (Dilantin) e cautiously taste perversion, patient after 8
active benigngastric enzymesystem by decreasing the with arthralgia, weeks of therapy for
ulcer; GERD, atthesecretorysur elimination of these pregnancy,lact myalgia, urticaria,
gastroreflux
Drug severeerosive face of the drugs by the liver.The ation. dry mouth, disorders; not
Classification: esophagitis, gastricparietalcell absorption of certain dizziness, intendedfor
proton pump poorlyresponsive s;blocks thefinal drugs may be affected headache, maintenance
inhibitors (PPI) symptomatic step by stomach acidity. paraesthesia, therapy.
GERD;Long-term of acidproduction. Therefore, omeprazole abdominal pain, Administer antacids
therapy: Treatmentof as well as other PPIs skin rashes, with omeprazole, if
pathologic reduce the absorption weakness, back needed.
hypersecretoryconditio pain, upper Teaching points:
and concentration in
ns (Zollinger- respiratory Take the drug
blood infection, cough.
Ellisonsyndrome, before meals.
multiple of ketoconazole (Nizor Swallow
adenomas,systemic al) and increase the thecapsules whole;
mastocytosis);Eradicati absorption and Potentially do not chew, open,
on of  concentration in blood Fatal: Anaphylaxi or crushthem. This
H. pylori  of digoxin (Lanoxin). s. drug will need to be
Withamoxicillin or This may reduce the taken for up to 8wk
metronidazole. effectiveness of (short-term therapy)
ketoconazole or for a prolonged
orincrease digoxin period(> 5 yr in
some cases).Have
toxicity
regular medical
follow-up visits.
Patient: A. De Vera. Age: 19
Date admitted: 3/5/20. Time admitted: 6:35 pm

Drug Brand Indication Action Side effects Nursing


Name Management
This drug is Trimetazidine is a  Rare Use cautiously in
TRIMETAZIDIN Vastarel recommended cellular acting anti- causes of patients with heart
E in long term ischaemic agent. It GI failure or
treatment of has 3 main properties disorders. hypertension and
coronary by which it acts as a  Nausea in elderly patients.
insufficiency ; cytoprotective agent. and
angina It inhabits the vomiting
pectoris. anaerobic glycolysis.  Fever
This action helps to  Rash
restore the energy  Respiratory
balance in the cell. It illness
inhibits acidosis and  Anemia
free radical
accumulation in the
cell. All these action
help the cell to restore
the normal ionic and
metabolic balance.
Generic Name Dosage and Route of Mechanism Indication Contraindication Adverse Effects Nursing
Administration of Action

Aspirin Arthritis Blocks pain Mild to Hypersensitivity to *HEMA: *Liver fun


(as’pir-in) Adult: 2.6-5.2 g/day in divided
impulses in moderate pain salicylates tatrazin, GI Thrombocytopenia, ALT, bilir
acetylsalicylic acid doses q4-q6h CNS, inhibition or fever bleeding, bleeding aggranulocytosis, patient is o
Child: 90-130 mg/kg/day in of prostaglandin including disorders, chidren<12 leukopenia, neutropenia, *Renal fun
Brand Name: divided doses q4-q6 dses q4h synthesis; rheumatoid yr, children with flulike hemolytic anemia urine creati
Arthrinol, Arthrisin, antipyretic arthritis, symptoms, Pregnancy *CNS: Stimulation, long term t
Aspergum Bayer Pain/Fever action results osteoarthritis, (3rd Trimester), drowsiness, dizziness, *Blood St
Aspirin, Coryphen, Adult: 325-650 mgq4h prn, from thromboembol lactation, vit K confusion, convulsion, Hgb, pro-ti
Easpirin, Ecotrin, not 4g/day vasodilation of ic disorders; deficiency, peptic ulcer flushing, hallucinations, long term t
Empirin, Entrophen Child: 40-100 mg/kg/day in peripheral transient coma *I&O ratio
divided doses q4-6h prn vessels; ischemic *GI: Nausea and vomiting, may indica
Classifications: decreases attacks, *GI bleeding, diarrhea, *Hepatotox
Nonnarcotic Kawasaki Disease platelet rheumatic heartburn, anorexia, clay-colore
analgesic, Child: 80-120 mg/kg/day in 4 aggregation. fever, hepatitis of skin,
nonsteroidal anti- divided doses postmyocardia *INTEG: Rash, urticuria, abdominal
inflammatory, l infarction, bruising diarrhea
antipyretic, Throomboembolic Disorders: prophylaxis of *EENT: Tinnitus, hearing *Visual c
antiplatelet Adult: 325-650 mg/day or bid MI, ischemic loss halos; corn
stroke, angina *CV: Rapid pulse, Edema in f
pulmonary edema
*RESP: Wheezing,
hypernea
*ENDO: Hypoglycemia,
hyponatremia, hypokalemia
*SYST: Reye’s Syndrome
DRUG ORDER MECHANISM INDICATIONS CONTRAINDICATIONS ADVERSE NURSING
OF EFECTS CONSIDERATIONS
ACTION

GENERIC NAME: Nitrates are drugs Prevention and The presence of any allergies to Instruct patient to take
that act directly on treatment of Angina (CNS)
nitrates. These drugs are also medication as directed,
the smooth muscle Pectoris in Adults contraindicated in the following Headache, even if feeling better. Take
ISOSORBIDE to cause relaxation conditions: Severe anemia, head dizziness, and missed doses as soon as
MONO NITRATE and to depress trauma or hemorrhage, remembered; doses of
(ISMN) muscle tone. pregnancy and lactation. myasthenia. (GI) isosorbide dinitrate should
N & V and be taken at least 2 hr apart
BRAND NAME: incontinence. (6 hr with extended-release
IMDUR 60mg preparations); daily doses
( CV) of isosorbide mononitrate
Hypotension. should be taken 7 hr apart.
Do not double doses. Do
CLASSIFICATION: (SKIN)
not discontinue abruptly
ANTI-ANGINAL Flushintg pallor
DRUGS sweating and
increased Caution patient to make

DOSAGE: perspiration position changes slowly to


½ tab minimize orthostatic
hypotension
ROUTE:
PO

FREQUENCY:
OD
Patient: P. Maningding Age: 50
Date admitted : 3/3/20. Time admitted: 8:12 am

Drug CLASSIFICATIO Action Contraindica Sde effects Nursing


Name N / INDICATION tion consediratiom
Exerts a relaxant
Betahist Anti vertigo drug action on the Hyperaensitivi  Mild  Instruct
amine precapillary ty to gastric patient that
sphincters of the betahistine or complai drug should
microcirculation of to any of the nts be taken
the inner ear, and excipients of  Skin with food.
thereby increases serc. rashes  Patients
the blood supply to with
the striavascularis phaeochrm
of the labyrinth. ocytoma or
Investigations into brinchial
the acute, subacute asthma
and chronic effects should be
of betahistine in treated with
animals have extra care.
demonstrated the
low toxicity and
safety of the drug.

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