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    Cetirizine

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    Anonymous QqyLDoW1
    This document provides information about the drug cetirizine, including its indications, mechanism of action, dosage, side effects, interactions, nursing considerations, and patient education points. Cetirizine is an antihistamine used to relieve symptoms of allergic conditions like seasonal allergic rhinitis and hives. It works by blocking the effects of histamine at receptor sites. Common side effects include dizziness, drowsiness, and dry mouth. Patients should be advised to avoid driving or activities requiring alertness until they know how the drug affects them.

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    Download as PDF, TXT or read online from Scribd

    Cetirizine

    Uploaded by

    Anonymous QqyLDoW1
    60 views2 pages
    This document provides information about the drug cetirizine, including its indications, mechanism of action, dosage, side effects, interactions, nursing considerations, and patient education points. Cetirizine is an antihistamine used to relieve symptoms of allergic conditions like seasonal allergic rhinitis and hives. It works by blocking the effects of histamine at receptor sites. Common side effects include dizziness, drowsiness, and dry mouth. Patients should be advised to avoid driving or activities requiring alertness until they know how the drug affects them.

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    Cetirizine

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    cetirizine

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    This document provides information about the drug cetirizine, including its indications, mechanism of action, dosage, side effects, interactions, nursing considerations, and patient education points. Cetirizine is an antihistamine used to relieve symptoms of allergic conditions like seasonal allergic rhinitis and hives. It works by blocking the effects of histamine at receptor sites. Common side effects include dizziness, drowsiness, and dry mouth. Patients should be advised to avoid driving or activities requiring alertness until they know how the drug affects them.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    60 views2 pages

    Cetirizine

    Uploaded by

    Anonymous QqyLDoW1
    This document provides information about the drug cetirizine, including its indications, mechanism of action, dosage, side effects, interactions, nursing considerations, and patient education points. Cetirizine is an antihistamine used to relieve symptoms of allergic conditions like seasonal allergic rhinitis and hives. It works by blocking the effects of histamine at receptor sites. Common side effects include dizziness, drowsiness, and dry mouth. Patients should be advised to avoid driving or activities requiring alertness until they know how the drug affects them.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    of 2

    Name /bks_53161_deglins_md_disk/cetirizine 02/11/2014 09:37AM Plate # 0-Composite pg 1 # 1

    1 Adverse Reactions/Side Effects


    CNS: dizziness, drowsiness (significant with doses ⬎10 mg/day), fatigue. EENT: PDF Page #1
    cetirizine (se-ti-ra-zeen) pharyngitis. GI: dry mouth.
    Aller Relief, Reactine, ZyrTEC Interactions
    Classification Drug-Drug: Additive CNS depression may occur with alcohol, opioid analge-
    Therapeutic: allergy, cold, and cough remedies, antihistamines sics, or sedative/hypnotics. Theophylline maypclearance andqtoxicity.
    Pharmacologic: piperazines (peripherally selective)
    Pregnancy Category B Route/Dosage
    PO (Adults and children ⱖ6 yr): 5– 10 mg given once or divided twice daily.
    PO (Children 2– 5 yr): 2.5 mg once daily initially, may beqto 5 mg once daily or
    Indications 2.5 mg every 12 hr.
    Relief of allergic symptoms caused by histamine release including: Seasonal and pe- PO (Children 1– 2 yr): 2.5 mg once daily; may beqto 2.5 mg every 12 hr.
    rennial allergic rhinitis, Chronic urticaria. PO (Children 6– 12 mo): 2.5 once daily.
    Action Hepatic/Renal Impairment
    Antagonizes the effects of histamine at H1-receptor sites; does not bind to or inactivate PO (Adults and Children ⱖ12 yr): CCr ⱕ31 mL/min, hepatic impairment or he-
    histamine. Anticholinergic effects are minimal and sedation is dose related. Thera- modialysis— 5 mg once daily.
    peutic Effects: Decreased symptoms of histamine excess (sneezing, rhinorrhea, Hepatic/Renal Impairment
    ocular tearing and redness, pruritus). PO (Children 6– 11 yr): start therapy at ⬍2.5 mg/day.
    Pharmacokinetics Hepatic/Renal Impairment
    Absorption: Well absorbed following oral administration. PO (Children ⬍6 yr): use not recommended.
    Distribution: Unknown. NURSING IMPLICATIONS
    Protein Binding: 93%.
    Metabolism and Excretion: Excreted primarily unchanged by the kidneys. Assessment
    Half-life: 7.4– 9 hr (pin children to 6.2 hr,qin renal impairment up to 19– 21 ● Assess allergy symptoms (rhinitis, conjunctivitis, hives) before and periodically
    hr). during therapy.
    ● Assess lung sounds and character of bronchial secretions. Maintain fluid intake of
    TIME/ACTION PROFILE (antihistaminic effects) 1500– 2000 mL/day to decrease viscosity of secretions.
    ROUTE ONSET PEAK DURATION ● Lab Test Considerations: May cause false-negative result in allergy skin test-
    PO 30 min 4–8 hr 24 hr ing.

    Contraindications/Precautions Potential Nursing Diagnoses


    Ineffective airway clearance (Indications)
    Contraindicated in: Hypersensitivity to cetirizine, hydroxyzine or any compo- Risk for injury (Adverse Reactions)
    nent; Lactation: Excreted in breast milk; not recommended for use.
    Use Cautiously in: Patients with hepatic or renal impairment (doseprecom- Implementation
    mended if CCr ⱕ31 mL/min or hepatic function is impaired); OB, Pedi: Safety not ● Do not confuse cetirizine with sertraline. Do not confuse Zyrtec (cetiri-
    established for pregnant women or children ⬍6 mo; Geri: Initiate at lower doses. zine) with Lipitor (atorvastatin), Zantac (ranitidine), Zocor (simvasta-
    ⫽ Canadian drug name. ⫽ Genetic Implication. CAPITALS indicate life-threatening, underlines indicate most frequent. Strikethrough ⫽ Discontinued.
    Name /bks_53161_deglins_md_disk/cetirizine 02/11/2014 09:37AM Plate # 0-Composite pg 2 # 2

    2
    tin), Zyprexa (olanzapine), Zyrtec-D (cetirizine/pseudoephedrine), PDF Page #2
    Zyrtec Itchy Eye Drops (ketotifen fumarate).
    ● PO: Administer once daily without regard to food.

    Patient/Family Teaching
    ● Instruct patient to take medication as directed.
    ● May cause dizziness and drowsiness. Caution patient to avoid driving or other ac-
    tivities requiring alertness until response to medication is known.
    ● Advise patient to avoid taking alcohol or other CNS depressants concurrently with
    this drug.
    ● Advise patient that good oral hygiene, frequent rinsing of mouth with water, and
    sugarless gum or candy may minimize dry mouth. Patient should notify dentist if
    dry mouth persists ⬎2 wk.
    ● Instruct patient to contact health care professional if dizziness occurs or if symp-
    toms persist.
    Evaluation/Desired Outcomes
    ● Decrease in allergic symptoms.
    Why was this drug prescribed for your patient?

    䉷 2015 F.A. Davis Company

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