Hypothermia in Patients Resuscit A Nontraumatic Cardiac Arrest

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HARBORVIEW MEDICAL CENTER Patient Care Services

CRITICAL CARE GUIDELINES

SUBJECT: HYPOTHERMIA IN PATIENTS RESUSCIT A NONTRAUMATIC


CARDIAC ARREST

APPROV AL: Chair, Critical Care Advisory Committee Assistant Administrator, Patient
Care Services

OBJECTIVE: To minimize hypoxic brain injury in patients recovering from in- or out-of-
hospital non-traumatic cardiac arrest

INCLUSION: Emergency Department; all Critical Care Units

EFFECTIVE DATE: December 5, 2002

Background: Anoxic brain injury is a major source of morbidity and mortality after cardiac
arrest. However, there is a large body of experimental evidence and two
prospective, randomized clinical trials that suggest that mild-moderate
hypothermia protects the brain during global ischemia after primary non-
traumatic cardiac arrest (ventricular fibrillation), and leads to improved
neurologic outcome. (N Engl J Med 2002; 346:549-56, 557-63, 612-3). In
addition, the ACLS Guidelines (October, 2000) recommend the maintenance
of mild hypothermia (temperature >33°C) after cardiac arrest (level of
evidence Class lIb).

Indications: All comatose patients after VF jVT, PEA, or asystolic non-traumatic cardiac
arrests with no contraindications to mild hypothermia.

Contraindications: Recent trauma, burns, or surgery, hemodynamically significant bleeding or


bleeding diathesis, refractory arrhythmias.

Specifics: The goal temperature for the first 24 hours post-resuscitation is a core body
temperature (esophageal) of 33°C. Specific recommendations for temperature
management are as follows:

If temperature is > 34°C


• Place Cooling Blanket under patient. Set blanket temperature to lO°C.
• Place Polar Bair Blanket over patient. Set blanket temperature to lowest setting of 1O°C.
• Place 6 ice packs on patient - 1 under neck, 1 on top of neck, 1 in each axilla, 1 in each groin.

• If no Polar Bair available use another Cooling Blanket (plugged into same machine) placed over
patient.

If temperature is between 32°C and 34°C


• Leave patient uncovered as modesty allows.
• DO NOT USE ANY METHODS OF COOLING OR WARMING.

If temperature is < 32°C


• Apply warm blankets.
• If temperature does not move _32°C after 30 minutes, use warming methods such as the Bair Hugger
or warm fluids ONLY until temperature reaches 32°C, then STOP warming methods.

For patients with shivering and or agitation, meperidine and diazepam should be administered, with
consideration of neuromuscular blockade in refractory cases.

Rewarming after 24 hours, or sooner if the patient awakens, should be passive.

These guidelines can be applied by initiating the complementary order form entitled "Hypothermia
Protocol For Comatose Patients Resuscitated From Nontraumatic Cardiac Arrest", which includes
specific interventions and drug doses.

Version 5, 12/11/02

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