PN1817187
PN1817187
PN1817187
Notes:
Method: Spectrophotometric
Ms.DHANYAMOL K
Lab Technician
Status : FINAL REPORT Dept of Biochemistry
DDRC SRL PANDALAM Tel:-9496005050
Page 1 of 4
DDRC SRL DIAGNOSTICS PRIVATE LIMITED
DDRC SRL, Building No. 651/ C/ VIII,
Opp.C.M.Hospital, M.C.Road, Pandalam - 689 501.
Mail: [email protected] Phn :9496005050
CIN:U85190MH2006PTC161480
Notes:
Test :Total Calcium Sample : Serum Method : NM - BAPTA
Calcium is the major mineral component of bone.Total calcium determines the concentration of calcium in blood which exist in free ions and bound
forms(Bound to albumin,anions,other proteins etc).Its used for the diagnosis and monitoring of a disorders associated with
Vitamin-D,Bone,Kidney,Parathyroid gland and Gastro-intestinal tract, mainly.It can be increased in conditions associated with Hyperparathyroidism,
Renal failure,certain Malignancy,Granulomatous diseases,certain Drug-intake,Thyrotoxicosis etc. It can be decreased in conditions associated with
Hypoparathyroidism,Rhabdomyolysis,Acute severe illness(Pancreatitis,Sepsis) ,Respiratory alkalosis.certain Drug-intake etc.
Clinical correlation by a professional is neccessary to rule out conditions associated with spurious serum calcium results in regards to altered Total
protein and Albumin levels,pH imbalances,altered anion levels, critically ill status,Renal failure,Liver transplantation etc.
Critical value(Children) : < 6.5mg/dL and >12.7 mg/dL. Critical value(Adult) : < 6.0mg/dL and >13.0 mg/dL.
VANUSREE .M
LAB TECHNICIAN
Status : FINAL REPORT DEPT. OF BIOCHEMISTRY
DDRC SRL,THIRUVALLA MOB:-9497717852
Page 2 of 4
DDRC SRL DIAGNOSTICS PRIVATE LIMITED
DDRC SRL, Building No. 651/ C/ VIII,
Opp.C.M.Hospital, M.C.Road, Pandalam - 689 501.
Mail: [email protected] Phn :9496005050
CIN:U85190MH2006PTC161480
DEPARTMENT OF HORMONES
Notes:
TSH estimations are used as a thyroid function test, in investigating low T4 results, in the differential diagnosis of primary hypothyroidism from
pituitary/hypothalamic hypothyroidism and monitoring therapy. A normal result on a sensitive TSH assay is acceptable evidence for adequate thyroid
replacement. This assay has a sensitivity of 0.001 mIU/L and meets all criteria as a 3rd Generation TSH assay.Secretion of T3 and T4 is regulated by
TSH through a negative feedback mechanisms involving the Thyroid, Pitutary and Hypothalamus.
METHOD: CLIA
Method: CLIA
SHEELA SUSAN
LAB TECHNICIAN
Status : FINAL REPORT DEPT. OF HORMONES
DDRC SRL,THIRUVALLA MOB:-9497717852
Page 3 of 4
DDRC SRL DIAGNOSTICS PRIVATE LIMITED
DDRC SRL, Building No. 651/ C/ VIII,
Opp.C.M.Hospital, M.C.Road, Pandalam - 689 501.
Mail: [email protected] Phn :9496005050
CIN:U85190MH2006PTC161480
DEPARTMENT OF HORMONES
Notes:
** Kindly please notice the modifications made in the Normal value according to Endocrine Society , Vitamin D council & Food and Nutritional board
Notes : Vitamin D is a fat soluble vitamin with important physiological functions in our body. Cholecalciferol (Vit D3) and Ergocalciferol (Vit D2) are the
two types of Vitamin D which our body can use for its needs. Vit D3 is synthesized in our body from cholesterol through a sun-light mediated reaction,
as well as its also received through dietary sources. On the other hand Vit D2 is received only by dietary sources. So Vit D status in a person is
influenced by the Diet, Latitude, Sun-exposure, Season, Age, Skin pigmentation and Sun-screen use. Taking dietary factor into consideration its
prefferable to take Vit D samples in a fasting status.
Absorbed Vit D from intestine is transferred to liver, by chylomicrons for storage, and its storage form is reffered as 25-Hydroxy Vitamin D.From here its
transported by Vitamin D Binding Protein (VDBP) to kidney, where its converted to its active/functional form,that is 1,25-dihydroxy Vitamin D (Calcitriol),
through a Parathyroid Hormone (PTH) mediated reaction.
Thus formed Calcitriol,helps in the calcium homeostatis and thereby in maintainance of skeletal health.Vit D also got certain non-skeletal effects in areas
of Epithelial differentiation,Lung function,Immunity etc.So estimation of Vitamin D is also done for the diagnosis and management of various disorders
like Rickets, Osteomalacia, Allergy,Asthma, Psoriasis etc.
Barring few exceptions, Total 25-hydroxy Vit D is preferred rather than Calcitriol for assessing Vit D status, as 25-hydroxy Vit D form is the main
circulating form with less technical complicity for estimation,day to day variation, and high half life than Calcitriol.
Total 25-hydroxy Vit D values can also be affected by certain factors Malabsorption ,breast feeding, Gastric/small bowel resection,drugs, Liver diseses
and Kidney diseases.
Total 25-hydroxy Vit D assays should measure its 25-hydroxy Vitamin D2 and 25-hydroxy Vitamin D3 forms in equimolar concentrations, with least cross
reactivity to other result interfering factors especially like C-3-epimer form of 25-hydroxy Vitamin D and 24,25-dihydroxy Vitamin D. The presence of
previously mentioned interferents can affect the result mostly by giving falsely elevated value.
ABHITHA .B
LAB TECHNICIAN
Status : FINAL REPORT DEPT. OF HORMONES Page 4 of 4
DDRC SRL,THIRUVALLA MOB:-9497717852