This document provides a review of Vatarakta (gout) according to Ayurvedic texts and its similarities to gout described in modern medicine. It discusses the etiology, pathogenesis and clinical features of Vatarakta as being similar to gout. Factors that can provoke attacks of gout like dehydration and a high purine diet are also discussed. The management of Vatarakta based on Ayurvedic principles like changes in diet and lifestyle as well as treatment modalities are reviewed as a challenge given the chronic nature and potential complications of the disease.
This document provides a review of Vatarakta (gout) according to Ayurvedic texts and its similarities to gout described in modern medicine. It discusses the etiology, pathogenesis and clinical features of Vatarakta as being similar to gout. Factors that can provoke attacks of gout like dehydration and a high purine diet are also discussed. The management of Vatarakta based on Ayurvedic principles like changes in diet and lifestyle as well as treatment modalities are reviewed as a challenge given the chronic nature and potential complications of the disease.
This document provides a review of Vatarakta (gout) according to Ayurvedic texts and its similarities to gout described in modern medicine. It discusses the etiology, pathogenesis and clinical features of Vatarakta as being similar to gout. Factors that can provoke attacks of gout like dehydration and a high purine diet are also discussed. The management of Vatarakta based on Ayurvedic principles like changes in diet and lifestyle as well as treatment modalities are reviewed as a challenge given the chronic nature and potential complications of the disease.
This document provides a review of Vatarakta (gout) according to Ayurvedic texts and its similarities to gout described in modern medicine. It discusses the etiology, pathogenesis and clinical features of Vatarakta as being similar to gout. Factors that can provoke attacks of gout like dehydration and a high purine diet are also discussed. The management of Vatarakta based on Ayurvedic principles like changes in diet and lifestyle as well as treatment modalities are reviewed as a challenge given the chronic nature and potential complications of the disease.
International Journal of Ayurveda and Pharma Research
Review Article
A COMPREHENSIVE STUDY OF VATA RAKTA W.S.R. TO GOUT
Vikas Rana1*, Anjana Mishra2, B.L.Mehra3 *1Kayachikitsa, 2Reader, 3H.O.D., P.G. Department of Kayachikitsa, R.G.G.P.G.Ayu.College & Hospital, Paprola, H.P., India. ABSTRACT The rapid modernization in India, fast food culture, stressful and speedy life, prevalent in urban areas is spreading its wings in remote villages too. Nowadays human beings are vulnerable to many disorders due to their altered life style and food habits. Among such metabolic disorders Vatarakta is one of them. Vatarakta is more distressing and common metabolic disorder prevalent in present era. It is characterised by severe pain, tenderness, inflammation and burning sensation in the affected joints. It is a Vatapradhana tridoshaja vyadhi where Rakta is main Dushya. Vatarakta is an illness where both Vata and Rakta are afflicted by distinct aetiological factors. Sedentary lifestyle along with mental stress, consumption of non- vegetarian and highly protein diet, excessive alcohol intake are some of the precipitating factors which causes acute exacerbation of Vatarakta. The aetiological factors responsible for Gouty arthritis, pathology and clinical features are quite similar with the Vatarakta. Due to excruciating pain, inflammation, joint deformity and restricted joint movements with the risk of various complications like urate nephropathy and urate nephrolithiasis its necessary to have a complete overview on all aspects of disease for treatment. Management of Vatarakta is a challenge as it is a disease of severe morbidity, chronicity and incurable to certain extent with associated complications. With certain life style modifications like low protein diet etc. and certain Ayurveda modalities viz. Shodhana and Shamana Chikitsa its can be cure and prevented. KEYWORDS: Ayurveda, Vatarakta, Vata, Rakta, Gouty arthritis. INTRODUCTION The health of an individual depends solely on the affected joints. It has two stages i.e., Uthana and his/her diet and lifestyle. Nowadays human beings are Gambhira.[1,3] Gambhira Vatarakta mainly affects more vulnerable to metabolic disorders due to their faulty Asthidhatu and Causes Ruja which spreads as Aakhorvisha dietary habits and life style. These disorders may be (rat poison).[2] Intense painful condition, initial site of causing functional impairment or crippling disorders like manifestation i.e. involvement of hands and feet, and other Vatarakta. The disorder produced by conjugation of clinical features can be compared with gout described in vitiated Vata and Rakta generate multiple health ailments modern medicine. The gout is also known as “disease of and most important of them is Vatarakta.[1] Hence it has kings” and also “king of diseases” in modern medicine.(7) been described as a separate disease entity in Charaka Gout is a metabolic disorder and inflammatory response to Samhita. There are many references along with description monosodium urate crystals formed secondary to of this disease in classical texts under the name of hyperuricemia.[9] In 21st century, gout remains the most Vatarakta, Adhyavata, Vatabalasa and Khuddavata. [1,3] The common inflammatory arthritis in men over 40 years old rich those who have plenty of resources and are delicate, and in post–menopausal women, although more common are mostly affected with the disease so it also named as in men (10:1). The number of cases rise with age, from Aadhyavata. Similarly, “Khudda” means joint and small, 2/1000 in males aged 18 - 44 and 34/1000 in males of age hence the disease affecting mostly the smaller joints of the 45-65 years. Number of self-reported cases of gout in body is called as Khuddavata. U.S.A. increased from 2.1 million to 3.0 million over a ten Both Vataprakopak and Raktaprakopaknidan are year period (from 1990-99) making it more prevalent than involved in Samprapti of the disease.[2] When a person R.A.[11] Its prevalence is increasing; more over it is a does not opt for purification processes like Vamana and potential signal for unrecognized comorbidities like Virechana or due to trauma, Raktadhatu gets vitiated. The obesity, metabolic syndrome, diabetes mellitus, same individual with vitiated Raktadhatu when starts hypertension and renal disease etc. Patients of gouty taking Vata-prakopakahara and Vihara, become prone to arthritis land up in severe joint destructions. The common Vata-vridhhi. Already vitiated Raktadhatu obstructs the complications in patients of gout are urate nephropathy, path of Vridhhvata, in which the Vata has to flow. Vitiated uric acid nephropathy and nephrolithiasis.[8] Due to its Vata becomes Aavrut with vitiated Raktadhatu. Vridhh and remittent and relapsing nature and complications, there obstructed Vata inturn vitiates the whole Rakta and is no permanent cure of this disease, which is a manifests as Vatarakta.[1,14] It is characterised by severe challenge for 21st century. Management of Vatarakta is a pain, tenderness, inflammation and burning sensation in challenge as it is a disease of severe morbidity, chronicity
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Int. J. Ayur. Pharma Research, 2017;5(9):93-96 and incurable to certain extent with associated - Excessive intake of oil-cake preparations or raddish. complications. Though a number of drug regimens have - Excessive intake of Kulatha (Macrotyloma uniflorum), been advised for the management of gout in the modern Masha (Vigna mungo), Nishpavshaak (Dichous lablab), medicine like NSAIDs, Colchicine, Corticosteroids, Pinyak (Sesamum Indicum), leafy vegetables and Antihyperuricemic drugs and Uricosuric agents. [9] The sugarcane (Saccharum). entire above are associated with adverse effects and - Excessive intake of curd, Aranala (kanji), Sauvirak, certain limitations. So there is need to understand the Sukta (vinegar), Takra (butter milk), alcohol and wine. pathogenesis of the disease to break down the vicious Viharajanidana [1,2] circle of Doshas. In Ayurvedic texts, two types of treatment of Vatarakta are mentioned such as Samanya Chikitsa -Excessive anger, Divaswapan, Ratrijagran, Abhighata, (General management) and Vishishtha Chikitsa (Specific Ashuddhi, Acankramanasilata. treatment according to classification). In Vishishtha -Riding on elephant, horse and camel. Chikitsa after careful diagnosis on the basis of stages of -Excessive swimming, excessive sexual indulgence. disease i.e. Uthana or Gambhira specific treatment is Mansiknidana: [1] planned. -Akrodha, Acinta and Harshanityatva. AIMS AND OBJECTIVES Prkruti based Nidana[1,2] - To review the available literature in Ayurvedic text and - The individuals who are Sukumaar, obese and its correlation with modern literature on Gout. consuming unwholesome diet are mainly affected. - To review the Vatarakta in context of Gout. Overweight person also surrenders the exercise - To review the role of diet and life style in the prevention schedule so chances of getting Kaphamedasdusti are of Vatarakta. increased. Kaphamedasdusti further add up to the MATERIALS AND METHODS etiology of this disease. Conceptual Review Agantuja Nidana (Miscellaneous factors) Description of disease Vatarakta is given in - Exogenous factors which vitiate the Dosha and Dhatu. Brihattrayi and in all successive texts. From the period of Nidana of Vatarakta vis-à-vis Etiology of Gouty Charaka onwards, the disease Vatarakta has been Arthritis described as a separate disease entity. The comparison of etiology of the disease according Etymology to Ayurvedic as well as modern view is as follows. The disease which occurs due to the derangement 1. Lavana rasa- Dehydration is discussed as provocating of Vata and Rakta is known as Vatarakta (Shabda-Kalpa cause of gout attacks and salt is the leading cause of Druma). The disease caused due to Vatadohsa and dehydration. Excess salty food does not allow water to Raktadhatu is called as Vatarakta (Chakrapaniteeka).[1] The excrete out of the body and no flushing of uric acid from vitiated Raktadhatu obstructs Vata results in Vatasonita the body occurs. So Lavana rasa precipitate the gout. (Ashtanga Hridaya). [3] The disease which is resulted due to 2. Shaak- The intake of high purine rich diet like spinach vitiation of Vatadosha and Raktadhatu leading to the or asparagus, cauliflower etc. vegetables can cause gout specific Samprapti, is known as Vatarakta (Madhukosha attack. [13] teeka).[4] 3. Mulak, Kulath, Masha, Nishpaav- Raddish, legumes Synonym (dried beans, peas), pulses (along with testa) are rich in Aadhya Vata, Khudda Vata, Vata Balasa, Vatashonita, purine which on metabolism form uric acid as end Vatarakta. [1,3] product. [7] Nidana / Etiology 4. Dadhi, Takra- These dairy products are also rich in Different Nidana of Vatarakta have been mentioned in protein content so they can also increase the uric acid Ayurvedic texts and can be classified into following groups: level but according to recent researches, dairy products helpin reducing serum uric acid. 1. Aharaja Nidana - Causes related to dietary habits. 5. Anoopdeshiyamansa, Ambujamansa- All non- 2. Viharaja Nidana - Causes related to individual habits vegetarian foods mainly seafood like salmon, mackerel and environmental factors. and red meat contain large amount of purines. [8] 3. Mansika Nidana- Causes related to psychological 6. Arnala, Souvira, Shukta, Sura, Asava-These fermented factors. drinks also contain high purine content. According to 4. Agantuja Nidana- Exogenous factors. modern science, alcohol consumption is a significant 5. Prakriti based Nidana - Miscellaneous factors. risk factor for gout because it reduces urate excretion Aharaja Nidana ¹ ( ) and increases urate production in blood. [8] - Excessive intake of foods and drinks that are having 7. Anashana, Langhana– As in starvation like condition, Lavana, Amla and Katu rasa or Snigdha, Ushna, Klinna, body starts metabolizing its own tissues (purine rich) Ruksha, Ushna, Vidahi and Ksara in quality. for energy. So in this condition, amount of purine - Excessive intake of saline, sour, pungent, alkaline, converted to uric acid is raised. Starvation like stress unctuous (oil, greasy), hot and uncooked food. condition also hampered the kidney’s ability to excrete uric acid due to competition for transport between uric - Intake of flesh of aquatic and marshy land inhabiting acid and ketones. [8] animals. Available online at: http://ijapr.in 94 Vikas Rana, Anjana Mishra, B.L.Mehra. A Comprehensive Study of Vata Rakta w.s.r. to Gout 8. Mithyahara, Virudhhashan- Ingestion of food/drinks retention of acidic wastes in the blood including uric kept in lead lined container or its inhalation when acid, which should be flush out from the body, causing handling it on daily basis (occupationally like in hyperuricemia. plumbers, painters etc.) leads to chronic lead poisoning, 11. Achankraman–Gout is also known as “Disease of which is also an etiology factor for gout (V. Batuman et. Kings” or “Rich man’s Disease” since long time, because al, 1968). Other than this, excessive ingestion of certain it is linked with sedentary lifestyle. Though the disease drugs like aspirin, diuretics can be included in Mithya affects anyone in society but found to be more Ahara. [10] prevalent in persons with sedentary lifestyle. [10] 9. Ikshu, Mishthannabhojana– These food items are rich 12. Abhighataj–Trauma like stress full conditions is also a in fructose. Fructose rich diet (fruit juices and fructose trigger factor for gout attacks. [8] rich sweetened soda) is found to be the common cause 13. Ativyayam, Ativyavaya–Excessive muscular exertion for gout attacks. It increases uric acid production (by doing heavy work) leads to increased degradation during its phosphorylation by increasing adenosine of ATP into AMP, which helps in raising the uric acid triphosphate (ATP) degradation to adenosine level. [8] monophosphate (AMP), a uric acid precursor. So within 14. Sthaulya–Obesity, in present days, is not an minutes after ingestion of fructose infusion, uric acid independent cause but main risk factor of gout. concentration is increased. [10] According to Campion EW.et al, 1987, Body Mass Index 10. Shushkaahara –Water is responsible for diuresis in the (BMI) is a significant predictor for the development of body so removes acidic wastes from the body. gout. [10] Decreased amount of water inside the body causes Samprapti Samprapti of Vatarakta
Sancharan of vitiated Vata & Rakta in the whole body
Khaivagunaya in Raktavahstrotas
Obstruction in the path of vata and sthanasanshraya
Vatarakta
Uttana (superficial) Gambhira (deep seated)
Twaka mamsa ashrita Sandhigataashrita
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Int. J. Ayur. Pharma Research, 2017;5(9):93-96 Pathya- Apathya Vatarakta. Pathya and Apathya are very important factors Pathya for Vatarakta: The cereals like the old Barley, in the management of gout like metabolic disorder. So wheat, Sali as well as Shashtika types of rice should be along with medicine disease can be better controlled by included in diet. Leafy vegetables like Kakamachi (Solanum avoiding all such precipitating factors. nigrum), Vastuka (Chenopodium album), Soup of Adhaki CONCLUSION (Cajanus indicus), Chanaka (Cicer arietinum), Masura The prevalence of life style disorders is rising (Lentil), Mudga (Psoralea radiatus) added with Ghrita in rapidly. The best thing which can be done in current liberal quantity should be taken. Milk of cow, buffalo and scenario is to prevent it rather than cure. Vatarakta is also goat is Pathya for Vatarakta patients. [1,3] a life style disorder of today world. Excessive purine diet Apathyafor Vatarakta: Vatarakta patients should avoid and sedentary life style are the causative factor of the meats, seafood, high purine vegetables such as asparagus, disease. Disease can be controlled by adopting certain life spinach, peas, cauliflower or mushrooms and alcohol. style changes like excessive water intake, reducing body Persons should also not take hot, heavy Abhishyandiguna weight and low purine diets. In advance cases there may and Ushna veeryas food ingredients as Masha, Kullatha, be need of some herbal drugs which can remove excess curd, sugarcane, radish, alcohol, Tilataila, Kanji, Saktu, uric acid present in the body and alleviate symptoms of the jackfruit and brinjal etc. Also avoid sleep during day time, disease. exposure to heat, intercourse, excessive exercises and REFERENCES excessive intake of pungent, saline and alkaline taste. 1. VaidyaJadavaji Trikamji Acharya. Charaka Samhita of Incompatible diets should be avoided by the patients Chakrapanidutta (1992) edited by Publishers Munshi suffering from Vatarakta. Ram ManoharLal Pvt. Ltd. New Delhi. Management:-Two types of treatment of Vatarakta are 2. Kaviraj Dr. Ambika Dutta Shastri commentary. described. Sushruta Samhita (1987) Vol-I and Vol-II, a) Samanya Chikitsa (General management) Chaukhambha Sanskrit Sansthan Varanasi. b) Vishishtha Chikitsa (Specific treatment according to 3. Sharma Shiv. Ashtanga Hridaya Deepika Hindi Tika classification) (1996) by Publishers Khem Raj, Krishan das Samanya Chikitsa Prakashan Bombay. i. Shodhana Chikitsa 4. VaidyaLal Chandra Shastri. AshtangaSamgraha, Antahparimarjana Chikitsa ii. Shamana Chikitsa Sarvanga Sundari Vyakhya Sahit (1982) Ist edition. iii. Rakta-mokshana karma 5. Inderdeva Tripathi. Chakradutta (1994) Chaukhambha iv. Lepa Chikitsa Bahiparimarjana Chikitsa Sanskrit Bhawan Varanasi. Shodhanachikitsa includes Snehana karma, 6. Upadhyay Yodunanda. Madhav Nidanam Madhukosha Virechana karma and Basti.[1] Most commonly used drugs Sanskrit Commentory (1993) 22nd edition by for Shamanachikitsa in Vatarakta are Gokshura, Guduchi, Publishers Chaukhambha Sanskrit Bhawan. Madhuka, Punarnava, Trivrita etc. [1] and various Guggulu 7. Goldman and Bennet. Cecil Text Book of Medicine preparations. Predominant Dosha is recognized and 2004 Vol. II, Publication-Elsevier p.1703-1708. specific treatment is planned keeping the general principle 8. Braun Wals, Fauci. Harrison’s Principles of Internal of management in view. Most of these drugs have Medicine, 18th edition, 2010. Vatashamaka properties and Mutra-virechaka quality so 9. Sidharth N. Shah Chief editor. API Textbook of help in excretion of excess uric acid present in the body. Medicine vol.1, 8th edition 2008, Chief Association of Some formulations found to be effective are Manjishthadi Physicians of India, Mumbai. p. 283-287. Kvatha, Suranjana churana, Sukumaraka taila, Guduchadi 10. Robert L, Wortman & William M. Kelley (2001) - ghrita, Kaishore guggulu, Gokshuradi guggulu, Panchtikta Kelley’s Textbook of Rheumatology vol-II 6th edition ghrita guggulu, Simhanada guggulu and Punarnavamrita W.B. Saunders Company. p. 1339-1376. guggulu. [5] 11. Clinical Spectrum of Gout in South India, J Indian DISCUSSION Rheumatol Assoc 2002:10. The main causative factors for Vatarakta are 12. Bhardwaj S.et al. 2012 (P.G.Thesis)-Comprehensive excessive use of alcohol, high purine diet, non-vegetarian study of "vayuvridho vridna raktanavarita pthi”in diet, acidic and astringent foodstuffs, person leading reference to aetiopathogenesis of vatarakta and its sedentary life, excessive anger and emotional distress. management. Both Vata and Rakta play a major role in the pathogenesis 13. Nafria S.et al. 2014 (P.G.Thesis)-A Clinical Study to of Vatarakta. Vitiated Raktadhatu obstructs the path of Evaluate the Effect of Guduchyadi Ghrita in the Vridhhvayu, in which the Vayu has to flow. Vridhh and management of Vatrakta w.s.r. to Primary& Secondary obstructed Vata inturn vitiates the whole Rakta and this Hyperuricaemia. Dosha-dushya sammurchhana in joints manifests as *Address for correspondence Cite this article as: Dr. Vikas Rana Vikas Rana, Anjana Mishra, B.L.Mehra. A Comprehensive Study of Vata Dept. of Kayachikitsa Rakta w.s.r. to Gout. International Journal of Ayurveda and Pharma R.G.Govt. P.G. Ayu. College & Hospital, Research. 2017;5(8):93-96. Paprola, H.P., India. Source of support: Nil, Conflict of interest: None Declared Email: [email protected] Mobile: 09418884849
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