Types of Nail Disease

Types of Nail Disease
Nails are unique structures formed of keratin, just like hair and the superficial
skin layers. Nail diseases vary in etiology and morphology. The most common
types are presented here.
Yoko Design | Shutterstock
Fingernails protect the sensitive tips of the fingers from accidental trauma and are
formed by the layer of germinal tissue called the nail matrix.
The matrix can be found at the very base of the nail, hidden under the skin fold which
lies just below the proximal side of the nail. The nail matrix is part of the nail bed which
supports and nourishes the nail plate.
The nail folds hold the nail in position and anchor it to the skin, forming the cuticle. This
prevents microbial organisms from entering the nail bed and also keeps moisture out.
Nail discoloration
The normal nail is pale pink in color. The end of the nail that grows off the finger is white
because it has no connection with the vascular nail bed which supports the rest of the
nail plate. Nails can become discolored because of:
 Smoking tobacco
 The use of dyes such as those used for hair
 Certain medications including some chemotherapy drugs
 Infections of the nail bed
 Injury to the nail bed
 Subungual melanomas
 Silver toxicity, quinacrine toxicity and Wilson’s disease – the nails become bluish
 Several systemic illnesses including liver disease – the nails become white
 Renal failure – the nails become half-and-half
Bacterial paronychia
This is a condition caused by bacterial infection of the nail fold. It is more common in
those who always have their hands in contact with moisture, who bite their nails or
incorrectly manicure their nails, or are prone to eczematous conditions or small injuries
of the fingers.
Chronic paronychia
Here the nail fold is thickened, tender and mildly reddened. It is due to a mix of factors
such as chemical irritation, allergy and moist conditions, all of which predispose to
chronic fungal infection as well. The nail becomes distorted in many such cases with
accompanying discoloration.
Traumatic changes to the nail

Related Stories
 Age of psoriasis onset decides if the skin or joints act up first
The nail may become injured, leading to:
 Lifting of the nail by a subungual hematoma

 Loss of the nail plate if the injury is too severe
 Ridging of the nail or nail deformities if the nail matrix is traumatized
Elevation of the nail plate (onycholysis)

The nail can be lifted off the underlying nail plate by infection or trauma and appears
yellowish or white. This includes:
 Picking under the fingernails too far

 Pus formation under the nail plate
 Some fungal infections
 Psoriasis
 Certain systemic conditions such as bronchiectasis, thyroid disorders, anemia or
some autoimmune diseases
Ingrown nails
This condition is characterized by nails growing into the skin at the sides of the nail. This
causes pain and may predispose to infection. It is more common if the nail curves
inwards too sharply, or if the nails are not trimmed correctly (straight across, or, in the
case of fingernails, with a gentle curve). Trauma or tight footwear may also cause this
condition.
Nail thickening
Thickening of the toenails is a normal age-related change, but abnormal thickening is
also possible. This includes:
 Injury
 Fungal infection
 Ischemic circulation
 Arthritis
 Abnormal gait
 Tight shoes
 Psoriasis
Nail ridges
Longitudinal ridges running down the nail may occur in several systemic conditions,
such as:
 Severe anemia or malnutrition

 Aging
 Trauma
 Illness
 Eczema
 Rheumatoid arthritis
 Peripheral vascular disease
 Lichen planus
Nail splitting
The nail may flake into layers as it grows, due to:
 Constant application and removal of nail polish

 Hands in constant exposure to water
 Overuse of the fingernails
Nail deformities
The nail may be deformed if it is subject to trauma or fungal infection. The nail bed
injury forces the nail to grow in an abnormal way. Other abnormalities of nail shape
include:
 Pincer nails which are curved transversely so much that they appear like pincers,
seen as both a congenital hereditary form and acquired disease
 Dolichonychia or long nails in Marfan’s syndrome or hypopituitarism
 Brachyonychia refers to short narrow nails as seen in psoriatic arthropathy
 Parrot beak nails are seen in some cases of scleroderma
Nail changes in systemic disease

Allergic or autoimmune conditions may present with nail changes such as pitting in
psoriasis or splinter hemorrhages in bacterial endocarditis, or altered shapes, including
the koilonychia (spoon-shaped concave nails) of iron-deficiency anemia. Beau’s lines
are transverse depressions that occur following severe illness, malnutrition,
chemotherapy or nail injury, besides several other conditions. Clubbing may occur in
lung disease.
Rare conditions affecting the nails:

 Congenital nail anomalies: Nails may be malformed or absent in the nail-
patella syndrome.
 Tumors of the nail bed: Subungual melanomas and other skin cancers may
occur under the nail.
 As a sign of toxicty: Occasionally, symptoms of poisonings can manifest as nail
changes. For instance, arsenic produces white lines, while silver toxicity may
produce a bluish tinge.

Types of Nail Disease

Uploaded by

Copyright:

Available Formats

Types of Nail Disease

Uploaded by

Document Information

Original Description:

Copyright

Available Formats

Share this document

Share or Embed Document

Sharing Options

Did you find this document useful?

Is this content inappropriate?

Copyright:

Available Formats

Types of Nail Disease

Uploaded by

Copyright:

Available Formats

Types of Nail Disease

Yoko Design | Shutterstock

Traumatic changes to the nail

The nail may become injured, leading to:

 Lifting of the nail by a subungual hematoma

Elevation of the nail plate (onycholysis)

 Picking under the fingernails too far

 Severe anemia or malnutrition

 Constant application and removal of nail polish

Nail changes in systemic disease

Rare conditions affecting the nails:

You might also like