FOMX Cantor 06 PDF

Download as pdf or txt
Download as pdf or txt
You are on page 1of 6
At a glance
Powered by AI
The article discusses positive results from a Phase 3 study of FMX101 for acne vulgaris. Cantor Fitzgerald maintains an Overweight rating and $15 price target for Foamix Pharmaceuticals based on the potential for pipeline success to drive earnings growth.

The Phase 3 study showed that FMX101 was statistically superior to the vehicle in reducing inflammatory lesions and achieving IGA treatment success at week 12. Over 95% of participants reported no or mild skin tolerability at the treatment site and all secondary endpoints were met.

Cantor Fitzgerald believes the peak sales potential of Foamix Pharmaceuticals' pipeline, including FMX101, are underappreciated. Success could drive upward revisions to earnings not yet reflected in consensus estimates, supporting a higher stock price.

Equity Research

June 4, 2019
R

SPECIALTY PHARMACEUTICALS

Quick Take
Louise Chen Brandon Folkes, CFA Jennifer Kim
212-915-1794 212-294-8081 212-829-4860
[email protected] [email protected] [email protected]

Foamix Pharmaceuticals Ltd. (FOMX- $2.54)


Rating: Overweight
Price Target: $15.00
The Foam Stays On Top; Publication of Phase 3 Acne Data In JAAD Is Positive
7 Takeaways
6
■ Today, FOMX announced its Phase 3 study (Study 22) for FMX101 was
5
highlighted in JAAD. Study 22 was conducted to support FMX101's NDA
4 submission, which is currently under review by the FDA for the treatment of
3 inflammatory lesions of non-nodular moderate-to-severe acne vulgaris in patients
nine years of age and older.
06/18 09/18 12/18 03/19 06/19
FOMX ■ FMX101's safety and efficacy data underscore our positive investment thesis on
Created by BlueMatrix FOMX's stock. We continue to believe that the peak sales potential of its pipeline
products, including FMX101, are underappreciated.
■ The key findings from the Phase 3 study were that FMX101 showed highly
statistically significant superiority compared with vehicle in both primary
Market Data endpoints of absolute inflammatory lesion reduction and IGA treatment success at
week 12, with more than 95% of participants having no or mild skin tolerability
Market Cap (M) $138 scores at the treatment application site. Additionally, it met all secondary
endpoints.
52-Week Range $7.60-$2.30
Avg Daily Trad Vol (3 mos) 356,754 Summary
Shares Out (M) 54.4
FMX101 is the first topical formulation of minocycline to reach regulatory agency
review for the treatment of any disease. We think publication of this pivotal study in
JAAD underscores FOMX's innovative platform.
Investment Thesis
We reiterate our OW rating and 12-month PT of $15 on shares of FOMX. We
expect pipeline success to drive upward earnings revisions to levels not yet reflected
in consensus expectations and FOMX's stock higher. The company has proprietary
technology that we think it can successfully leverage to yield a number of new
treatments for unmet needs in dermatology (acne, rosacea, among others).
Valuation Summary
We arrive at our 12-month price target of $15 for FOMX shares by using a blend of
EV/EBITDA, DCF and Bull-, Bear- and Base-case analysis.

The Disclosure Section may be found on pages 3 - 5.


June 4, 2019

Valuation
We arrive at our 12-month price target of $15 for FOMX shares by using a blend of EV/
EBITDA, DCF and Bull-, Bear- and Base-case analysis.

Risks
There are larger, more-established companies with commercial products for the
treatment of dermatologic conditions. Therefore, FOMX could be unsuccessful in penetrating
the market. There are multiple treatment options currently available for the indications for
which FOMX is expecting to release its new drug candidates. Pricing, physician/patient uptake,
and superior characteristics over legacy players are factors that will affect market penetration.
Larger, more-established companies also have more resources to compete with if/when FOMX
brings new products to market.
FOMX plans to leverage its proprietary topical foam technology for future product
development programs and launches. There is a risk that this method will not be optimal for
treating other indications. Product development based off of one platform lacks diversity and
versatility to pivot in the case of failure. FOMX is looking to develop a product portfolio solely
based on its proprietary topical foam technology, and there is a risk that this technology will
not be suitable for multiple indications.
We are concerned that clinical trials, patent litigations, and the cost of day-to-day
operations will deplete available funds prior to the company reaching profitability.
Therefore, FOMX’s current reliance on raising funds to sustain operations is a risk. Any
delays or failures in clinical trial programs and/or adverse decisions regarding patent litigations
ongoing against Teva (TEVA: Neutral) and Perrigo (PRGO: OW) may cause FOMX to incur
unexpected costs. Because FOMX is not expected to generate revenue or be profitable in the
near term, this could be detrimental to its operational outlook. The company has incurred losses
since its inception, and it is challenging to foresee if funds will be available to sustain the
company to profitability.

2
June 4, 2019

Company Description
Foamix is a pharmaceutical company focused on the development and commercialization of proprietary, innovative and differentiated topical
drugs for dermatological therapy. The leading clinical-stage product candidates are based on a proprietary minocycline foam formulation.
Disclosures Appendix
Analyst Certification
The analyst primarily responsible for this research report, and whose name appears on the front cover, certifies that: (i) all of the views expressed in this
research report accurately reflects his or her personal views about any and all of the subject securities or issuers featured in this report; and (ii) no part
of any of the research analyst’s compensation was, is, or will be, directly or indirectly related to the specific recommendations or views expressed by the
research analyst in this report.

Legal Disclosures
Lead or Co-manager: Cantor Fitzgerald and/or its affiliates, has acted as lead or co-manager in a public offering of equity and/or debt securities for Foamix
Pharmaceuticals Ltd. within the last 12 months
Investment banking (last 12 months): Cantor Fitzgerald and/or its affiliates has received compensation for investment banking services in the last 12 months
from Foamix Pharmaceuticals Ltd..
Investment banking (next 3 months): Cantor Fitzgerald and/or its affiliates, expect to receive, or intend to seek, compensation for investment banking
services within the next three months from all of the companies referenced within this report.
Cantor Fitzgerald and/or its affiliates is a market maker in Foamix Pharmaceuticals Ltd..
Cantor Fitzgerald and/or its affiliates is a market maker in Perrigo Company.
Cantor Fitzgerald and/or its affiliates is a market maker in Teva Pharmaceutical Ind. Ltd..

Cantor Fitzgerald's rating system


Overweight/OW: The analyst expects that the stock’s total return (stock price appreciation plus dividends) will outperform relative to the analyst’s broadly
defined sector in the next 12 months. For the purpose of calculating the percentage of subject companies within the Buy, Hold, and Sell categories for whom
Cantor Fitzgerald has provided investment banking services within the previous 12 months, an Overweight rating equates to a Buy rating.
Neutral: The analyst expects that the stock’s total return (stock price appreciation plus dividends) will perform in line relative to the analyst’s broadly
defined sector in the next 12 months. For the purpose of calculating the percentage of subject companies within the Buy, Hold, and Sell categories for whom
Cantor Fitzgerald has provided investment banking services within the previous 12 months, a Neutral rating equates to a Hold rating.
Underweight/UW: The analyst expects that the stock’s total return (stock price appreciation plus dividends) will underperform relative to the analyst’s
broadly defined sector in the next 12 months. For the purpose of calculating the percentage of subject companies within the Buy, Hold, and Sell categories
for whom Cantor Fitzgerald has provided investment banking services within the previous 12 months, an Underweight rating equates to a Sell rating.
Not Covered/NC: Cantor Fitzgerald does not provide an investment opinion or does not provide research coverage on this stock.
Not Rated/NR: We are not currently carrying a rating on this stock. Rating and estimates are under review. The NR rating does not equate to an Overweight,
Neutral, or Underweight rating and thus is not counted in the calculation of the percentage of subject companies within these three categories for whom
Cantor Fitzgerald has provided investment banking services within the previous 12 months.

Other Disclosures
This report is for informational purposes only and is based on publicly available data believed to be reliable, but no representation is made that such data
are accurate or complete. Opinions and projections contained herein reflect our opinion as of the date of this report and are subject to change. Pursuant to
Cantor Fitzgerald's policy, the author of this report does not own shares in any company he/she covers.

Cantor Fitzgerald and the Cantor Fitzgerald logo are trademarks or registered trademarks of Cantor Fitzgerald Securities or its affiliates in the U.S. and
other countries. Other trademarks appearing herein are the property of their respective owners. Neither Cantor Fitzgerald Securities nor its affiliates are
associated with or affiliated with such third parties.
This material is being presented solely as institutional communications and is not meant to be viewed as a complete fundamental analysis of any security.
This material may offer recommendations and strategies which are shorter term in nature. If the material contains analysis, it may be narrowly focused,
and may be based either purely on quantitative models or other unique factors such as market supply/demand factors surrounding potential market moving
events. When making an investment decision this information should be viewed as just one factor in your investment decision process. Past performance
should not be taken as an indication or guarantee of future results.

Disclosures for UK investors


This material is approved for distribution in the United Kingdom by Cantor Fitzgerald Europe (“CFE”). CFE is authorised and regulated by the Financial
Conduct Authority (“FCA”). While we believe this information and the materials upon which this information was based is accurate, except for any

3
June 4, 2019

obligations under the rules of the FCA, we do not guarantee its accuracy. This material is only intended for use by eligible counterparties or professional
clients who fall within articles 19 or 49 of the Financial Services and Markets Act 2000 (Financial Promotion) Order 2001 and not the general investing
public. None of the investments or investment services mentioned or described herein are available to other persons in the U.K and in particular are not
available to "retail clients” as defined by the rules of the FCA.
Disclosure for Canadian Institutional Investors
This research report was prepared by analysts of Cantor Fitzgerald & Co. and not by Cantor Fitzgerald Canada Corporation. As a result, this report has not
been prepared subject to Canadian Disclosure requirements. Cantor Fitzgerald Canada may distribute research reports prepared by its affiliates.
Risks
The financial instruments discussed in this report may not be suitable for all investors and investors must make their own investment decisions based on
their specific investment objectives. Past performance should not be taken as an indication or guarantee of future performance. The price, value of and
income from, any of the financial instruments featured in this report can rise as well as fall and be affected by changes in economic, financial and political
factors. If a financial instrument is denominated in a currency other than the investor's currency, a change in exchange rates may adversely affect the price
or value of, or income derived from, the financial instrument, and such investors effectively assume currency risk. In addition, investors in securities such
as ADRs, whose value is affected by the currency of the home market of the underlying security, effectively assume currency risk.

Rating and Price Target History for: Foamix Pharmaceuticals Ltd. (FOMX) as of 06-03-2019
10/12/18
I:1:$15
12

10

2
Q1 Q2 Q3 2017 Q1 Q2 Q3 2018 Q1 Q2 Q3 2019 Q1 Q2

I = Initiated; 1 = Overweight/OW or before 12/14/16; B = BUY; 2 = Neutral or before 12/14/16; H = HOLD;


3 = Underweight/UW or before 12/14/16; S = SELL; SP = SPECULATIVE BUY before 12/14/16; NR = Not Rated; D = Dropped
Powered by BlueMatrix

Rating and Price Target History for: Perrigo Company (PRGO) as of 06-03-2019
06/15/17 08/10/17 09/12/17
I:1:$85 1:$93 1:$107
140
120
100
80
60
40
20
Q1 Q2 Q3 2017 Q1 Q2 Q3 2018 Q1 Q2 Q3 2019 Q1 Q2

I = Initiated; 1 = Overweight/OW or before 12/14/16; B = BUY; 2 = Neutral or before 12/14/16; H = HOLD;


3 = Underweight/UW or before 12/14/16; S = SELL; SP = SPECULATIVE BUY before 12/14/16; NR = Not Rated; D = Dropped
Powered by BlueMatrix

4
June 4, 2019

Rating and Price Target History for: Teva Pharmaceutical Ind. Ltd. (TEVA) as of 06-03-2019
06/15/17 08/03/17 09/08/17 11/02/17 12/21/17 07/13/18 05/02/19
I:2:$31 2:$27 2:$17 2:$10 2:$18 2:$25 2:$16
60
50
40
30
20
10
0
Q1 Q2 Q3 2017 Q1 Q2 Q3 2018 Q1 Q2 Q3 2019 Q1 Q2

I = Initiated; 1 = Overweight/OW or before 12/14/16; B = BUY; 2 = Neutral or before 12/14/16; H = HOLD;


3 = Underweight/UW or before 12/14/16; S = SELL; SP = SPECULATIVE BUY before 12/14/16; NR = Not Rated; D = Dropped
Powered by BlueMatrix

Distribution of Ratings/Investment Banking Services (IB) as of 06/04/19


Cantor
IB Serv./Past 12 Mos.
Rating Count Percent Count Percent
BUY [1/B] 163 77.25 78 47.85
HOLD [2] 48 22.75 4 8.33
SELL [SL/3] 0 0.00 0 0.00
(1)

Additional information available on request. Copyright (C) Cantor Fitzgerald 2019


5
U.S. Equity Research Analysts & Management

Biotechnology
Alethia Young Healthcare IT Specialty Pharmaceuticals
Head of Healthcare Research Brandon Folkes, CFA
Managed Care
212-359-8739 212-294-8081
[email protected] Steven Halper
212-915-1240 [email protected]

Emma Nealon [email protected]


212-558-4571 Financial Technology
[email protected] Kyle Mikson, CFA
Outsourcing
212-829-5207
Professional Services
Eileen Maysek [email protected]
212-915-1221
[email protected] Joseph Foresi
Life Science Tools & 212-610-2423
Charles C. Duncan, Ph.D. Diagnostics [email protected]
212-915-1236 Jordan Abrams
[email protected] 212-610-5588 Drew Kootman, CFA, CMT
[email protected] 212-829-5289
Pete Stavropoulos, Ph.D. [email protected]
212-915-1966 Medical Devices & Supplies
[email protected] Product Manager
Craig Bijou Alice Avanian, CFA
212-915-1219 212-915-1702
Varun Kumar, Ph.D.
[email protected] [email protected]
212-610-3509
[email protected]
Dennis Pak
212-294-8016
Matthew Lillis
[email protected]
212-915-1706
[email protected]
Specialty Pharmaceuticals
Eliana Merle, CFA Louise Chen
212-915 1767 212-915-1794
[email protected] [email protected]

Elemer Piros, Ph.D. Jennifer Kim


212-610-2416 212-829-4860
[email protected] [email protected]

Kristen Kluska
212-915-1927
[email protected]

You might also like