MATERIAL SAFETY DATA SHEET

XYLITOL
1. IDENTIFICATION OF SUBSTANCE/PREPARATION AND THE COMPANY UNDERTAKING

SUBSTANCE/PREPARATION:
XYLITOL
TRADENAME/SYNONYMS:
XYLITOL C, XYLITOL CM, XYLITOL CFP, XYLITOL CX
CHEMICAL FAMILY:
Pentahydroxypentone
MOLECULAR FORMULA:
C5-H12-O5
MOLECULAR WEIGHT:
152.15
EINECS NUMBER:
201-788-0
COMPANY:
DANISCO SWEETENERS
41-51 BRIGHTON ROAD
REDHILL
SURREY
RH1 2YS
UNITED KINGDOM

TELEPHONE TELEFAX
+ 44 1737 773 732 + 44 1737 773 117

2. COMPOSITION/INFORMATION ON INGREDIENTS

INGREDIENT CAS RN PERCENT

XYLITOL 87-99-0 98.5 – 101.0

3. HAZARD IDENTIFICATION

SKIN CONTACT:
SHORT TERM EFFECTS: No information is available.
LONG TERM EFFECTS: May cause irritation in susceptible individuals.
EYE CONTACT:
SHORT TERM EFFECTS: No information is available.
LONG TERM EFFECTS: May cause irritation with direct contact in susceptible individuals.
INHALATION:
SHORT TERM EFFECTS: No information is available.
LONG TERM EFFECTS: Prolonged exposure as a nuisance particle may result in respiratory
irritation in susceptible individuals or those with respiratory conditions.
INGESTION:
SHORT TERM EFFECTS: No information is available on significant adverse effects.
LONG TERM EFFECTS: Xylitol is approved for food use and is non toxic. As with all polyols
excessive consumption can cause laxation in sensitive individuals

MSDS No: H001/5 Supercedes MSDS No: H001/4 Date: 22/03/2007 1 of 6

 4. FIRST AID MEASURES

SKIN CONTACT:
Remove contaminated clothing and shoes immediately. Wash with soap or mild detergent and large
amounts of water until no evidence of chemical remains. Seek medical attention if needed.
EYE CONTACT:
Wash eyes immediately with large amounts of water or normal saline, occasionally lifting upper and
lower lids, until no evidence of chemical remains (at least 15-20 minutes). Obtain medical attention
immediately.
INHALATION:
Remove from exposure area immediately. Treat symptomatically and supportively. Seek medical
attention if needed.
ANTIDOTES:
No specific antidote. Treat symptomatically and supportively.

5. FIRE-FIGHTING MEASURES

FIRE CONTROL
Dry chemical, carbon dioxide, water spray or regular foam
For larger fires, use water spray, fog or regular foam.

FIRE AND EXPLOSION HAZARD:

Slight fire hazard when exposed to heat or flame.
Dust-air mixtures may ignite or explode.

FIRE-FIGHTING:
Move container from fire area if possible without risk. Do not scatter spilled material with
high-pressure water streams. Dike fire-control water for later disposal (1993 Emergency Response
Guidebook. RSPA P 5800.6, Guide Page 31).

Use agents suitable for type of surrounding fire. Avoid breathing hazardous vapours, keep upwind.

6. ACCIDENTAL RELEASE MEASURES

OCCUPATIONAL SPILL:
Sweep up and place in suitable containers for disposal. Do not flush spilled material into sewer.

7. HANDLING AND STORAGE

HANDLING:
Provide local exhaust or general dilution ventilation system.

STORAGE:
Observe all appropriate regulations when storing this substance.

MSDS No: H001/5 Supercedes MSDS No: H001/4 Date: 22/03/2007 2 of 6

 8. EXPOSURE CONTROLS/PERSONAL PROTECTION

EXPOSURE CONTROLS:
No permissible exposure limits established by Danisco, Australia, Belgium, Denmark, France,
Germany, United Kingdom (HSE) or United States (ACGIH, OSHA).

PERSONAL PROTECTION:

EYE PROTECTION:
Employee should wear splash-proof or dust resistant safety goggles to prevent eye contact with this
substance.

EMERGENCY EYE WASH:

Where there is any possibility that an employee's eyes may be exposed to this substance, the employer
should provide an eye wash fountain within the immediate work area for emergency use.

CLOTHING:
Employee should wear appropriate protective clothing and equipment to prevent repeated prolonged
skin contact with this substance.

GLOVES:
Employee should wear appropriate protective gloves to prevent contact with this substance.

RESPIRATOR:
The following respirators are recommended based on information found in the physical data, toxicity
and health effects sections. They are ranked in order from minimum to maximum respiratory
protection.

The specific respirator selected must be based on contamination levels found in the work place and the
specific operation, and must be jointly approved by the National Institute for Occupational Safety and
Health and the Mine Safety and Health Administration (NIOSH-MSHA). Contamination levels in the
work place must not exceed the working limits of the respirator

i) Any dust and mist respirator with a full facepiece.

ii) Any air-purifying full facepiece respirator with a high-efficiency particulate filter.

iii) Any powered air-purifying respirator with a tight-fitting facepiece and high-efficiency
particulate filter.

iv) Any type 'C' supplied-air respirator with a full facepiece operated in pressure-demand or other
positive pressure mode or with a full facepiece, helmet or hood operated in continuous-flow
mode.

FOR FIREFIGHTING AND OTHER IMMEDIATELY DANGEROUS TO LIFE OR HEALTH

CONDITIONS

v) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-
demand or other positive-pressure mode.

vi) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or
other positive-pressure mode in combination with an auxiliary self-contained breathing
apparatus operated in a pressure-demand or other positive-pressure mode.

MSDS No: H001/5 Supercedes MSDS No: H001/4 Date: 22/03/2007 3 of 6

 9. PHYSICAL AND CHEMICAL PROPERTIES

APPEARANCE: White crystalline or milled powder with a very sweet, cool taste.

FLASH POINT: no data available

AUTOIGNITION
TEMPERATURE: no data available

BOILING POINT: 215-217 oC

MELTING POINT: 92-96 oC

SPECIFIC DENSITY: 1.515g/cm3

WATER SOLUBILITY: highly soluble (1.6g/ml @ 20°C)

pH: 5.0 to 7.0

SOLVENT SOLUBILITY: Soluble in alcohols, pyridine.

10. STABILITY AND REACTIVITY

CONDITIONS TO AVOID:
May burn but does not ignite readily. Avoid contact with strong oxidisers, excessive heat, sparks, or
open flame.

REACTIVITY:
Stable under normal temperatures and pressures.

INCOMPATIBILITIES:
No data available.

HAZARDOUS DECOMPOSITION:
Thermal decomposition may release toxic and/or hazardous gases.

POLYMERISATION:
Hazardous polymerisation has not been reported to occur under normal temperatures and pressures.

MSDS No: H001/5 Supercedes MSDS No: H001/4 Date: 22/03/2007 4 of 6

 11. TOXICOLOGY AND INFORMATION

TOXICITY DATA:
22 gm/kg oral-mouse LD50; 22,100 mg/kg intraperitoneal-mouse. LDLo; 3770 mg/kg
intravenous-mouse LD50; 4000 mg/kg intravenous-rabbit LD50.

CARCINOGEN STATUS:
None

ACUTE TOXICITY LEVEL:

Relatively non-toxic by ingestion.

TARGET EFFECTS:
No data available.

HEALTH EFFECTS

INHALATION:
ACUTE EXPOSURE - No data available.
CHRONIC EXPOSURE - No data available.

SKIN CONTACT:
ACUTE EXPOSURE - No data available.
CHRONIC EXPOSURE - No data available.

EYE CONTACT:
ACUTE EXPOSURE - No data available.
CHRONIC EXPOSURE - No data available.

INGESTION:
ACUTE EXPOSURE - No data available.
CHRONIC EXPOSURE - The US Food and Drug Administration (FDA) lists xylitol as an approved
food additive for special dietary use. Xylitol is approved for use in foods in approximately 50
countries.

12. ECOLOGICAL INFORMATION

ENVIRONMENTAL IMPACT RATING (0-4):

No data available

ACUTE AQUATIC TOXICITY:

No data available.

DEGRADABILITY:
No data available.

LOG BIOCONCENTRATION FACTOR (BCF):

No data available.

LOG OCTANOL/WATER PARTITION COEFFICIENT:

No data available.

MSDS No: H001/5 Supercedes MSDS No: H001/4 Date: 22/03/2007 5 of 6

 13. DISPOSAL CONSIDERATIONS

Observe all federal, state and local regulations when disposing of this substance.

14. TRANSPORT INFORMATION

The MSDS should accompany all shipments for reference in the event of spillage or accidental
release.

No classification currently assigned.

15. REGULATORY INFORMATION

EUROPEAN UNION CLASSIFICATION AND LABELLING REQUIREMENTS:

European Union labelling requirements not determined.

16. OTHER INFORMATION

INFORMATION ON HAZARD LABELLING:

To be determined.

REFERENCES:
To be determined.

This MSDS is based on a review of Danisco files, literature references, toxicology handbooks and published MSDS’s on identical or related
materials, and is believed to be accurate. However, no warranty is expressed or implied regarding the accuracy of this data or the results to
be obtained from their use. Users should make their own investigations to determine the suitability of the information for their particular
purposes. Nothing herein shall constitute permission, inducement or recommendation to practice any invention covered by any patent owned
by Danisco Sweeteners or by others, nor as a recommendation to use any product or to practice any process in violation of any law or
government regulations.

MSDS No: H001/5 Supercedes MSDS No: H001/4 Date: 22/03/2007 6 of 6