HA Pumps Catalog Syringe Pumps

Download as pdf or txt
Download as pdf or txt
You are on page 1of 35

SYRINGE PUMPS

Choosing the Right Pump for Your Application & Budget


SYRINGE PUMPS

SYRINGE PUMP QUESTIONS


What is your application?
How many syringes will be used simultaneously?
What size syringe will be used?
What flow rate(s) will be used? See pump reference pages 102-106
What is the total volume to be delivered?
Does the pump need to withdraw (fill the syringe) as well as infuse (dispense)?
Selection Guide

Syringe Pump Selection Guide


INFUSION ONLY

MODEL PUMP 11 ELITE PUMP 22 ** PHD 22/2000 PHD ULTRA™ PUMP 11 ELITE PICO PLUS ELITE

PC1 70-4500
STANDARD PUMP PC1 55-2222 PC1 70-2000 PC1 70-3005
PC1 70-4501

PC1 70-4504
PROGRAMMABLE PUMP – – – – PC1 70-4506
PC1 70-4505

NUMBER OF SYRINGES 1 or 2 2 to 10* 2 to 10* 2 to 10* 1 or 2 2

MINIMUM SYRINGE SIZE 0.5 µl 0.5 µl 0.5 µl 0.5 µl 0.5 µl 0.5 µl

50/60 ml (single) 50/60 ml (single)


MAXIMUM SYRINGE SIZE 140 ml 140 ml 140 ml 10 ml
10 ml (dual) 10 ml (dual)

MINIMUM FLOW RATE 1.28 pl/min 0.002 µl/hr 0.0001 µl/hr 1.56 pl/min 1.28 pl/min 0.54 pl/min

88.28 ml/min (single) 88.28 ml/min (single)


MAXIMUM FLOW RATE 55.1 ml/min 220.82 ml/min 215.8 ml/min 11.70 ml/min
25.99 ml/min (dual) 25.99 ml/min (dual)

16 kg (35 lbs) 23 kg (50 lbs) 34 kg (75 lbs) 16 kg (35 lbs) 16 kg (35 lbs)
AVERAGE LINEAR FORCE 21 kg (47 lbs)
(adjustable) or 30 kg (66 lbs) (adjustable) (adjustable) (adjustable)

COMPUTER CONTROL USB RS-232 RS-232 USB + RS-232 USB USB

I/O + TTL CONNECTION No Yes Yes Yes Yes Yes

DIMENSIONS 22.6 x 17.78 x 15 cm 28 x 22.2 x 14 cm 15.9 x 22.8 x 27.9 cm 10.16 x 30.5 x 21.6 cm 22.6 x 17.78 x 15 cm 22.6 x 17.78 x 15 cm
(H x W x D) (9 x 7 x 6 in) (11 x 8.75 x 5.5 in) (6.3 x 9 x 11 in) (4 x 12 x 8.5 in) (9 x 7 x 6 in) (9 x 7 x 6 in)

PUMP HEAD DIMENSIONS


– – – – – –
(H x W x D)

WEIGHT 2.1 kg (4.61 lbs) 4.5 kg (10 lbs) 4.5 kg (10 lbs) 4.5 kg (10 lbs) 2.1 kg (4.6 lbs) 2.1 kg (4.61 lbs)

PAGE 11 26 29 16 11 14

Please contact Technical Support for assistance.

* Depends upon the Syringe Rack


4 x 140 Syringe Rack Holds four 60 ml or 140 ml plastic syringes only
6 x 10 Syringe Rack Holds six 30 to 60 ml syringes or ten 0.5 µl to 20 ml syringes
Microliter Syringe Rack Holds four 0.5 µl to 10 ml syringes
** Low RFI (Radio Frequency Interference) Pump available
*** Push/Pull pump can hold syringes up to 140 ml if full stroke is not required. Larger syringes will not fully infuse or withdraw. Max of 50 ml syringe if full stroke is required.

4 Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com
SYRINGE PUMPS
Choosing the Right Pump for Your Application & Budget
(continued)

SYRINGE PUMPS
SYRINGE PUMP QUESTIONS (CONTINUED)
What is the viscosity of the liquid you are pumping? See pump reference page 101
What are the pressure requirements of your experiment? See pump reference pages 101-102
Does the pump need to continuously infuse over a 24 hour period of time?
Does the pump need to be programmable?
Does the pump need to be controlled with a computer?
Does the pump need to have TTL capabilities (ex. external control of valves, use of footswitch, etc)?

Selection Guide
INFUSION/WITHDRAWAL PUSH/PULL

PUMP 11 ELITE PHD ULTRA™ PHD ULTRA™ PHD ULTRA™


PUMP 33 PHD 22/2000 PHD ULTRA™ PHD ULTRA™ HPSI
NANOMITE NANOMITE 4400 HPSI PUSH/PULL

PC1 55-3333 PC1 70-2001 PC1 70-3006 – – PC1 70-3008

PC1 70-3010
PC1 70-4507 PC1 70-3601 – PC1 70-2002 PC1 70-3007 PC1 70-3111 PC1 70-3009
PC1 70-3111

4 (2 on each side
1 1 2 2 to 10* 2 to 10* 4 1
of pusher block)

0.5 µl 0.5 µl 0.5 µl 0.5 µl 0.5 µl 20 ml 2.5 ml 0.5 µl

1 ml 1 ml 140 ml 140 ml 140 ml 200 ml 100 ml 140 ml***

3.66 pl/min 3.66 pl/min 0.0004 µl/hr 0.0001 µl/hr 1.56 pl/min 49.7 nl/min 3.06 pl/min 1.56 pl/min

3.818 ml/min 3.818 ml/min 106.6 ml/min 215.8 ml/min 215.8 ml/min 144.1 ml/min 215.8 ml/min 215.8 ml/min

5 kg (11 lbs) 5 kg (11 lbs) 23 kg (50 lbs) 34 kg (75 lbs) 197 kg (433 lbs) 91 kg (200 lbs) 34 kg (75 lbs)
26 kg (57 lbs)
(adjustable) (adjustable) or 30 kg (66 lbs) (adjustable) (adjustable) (adjustable) (adjustable)

USB USB RS-232 RS-232 USB + RS-232 USB + RS-232 USB + RS-232 USB + RS-232

Yes Yes Yes Yes Yes Yes Yes Yes

22.6 x 17.78 x 9.32 cm 30.5 x 21.6 x 11.1 cm 15.2 x 31.1 x 28.6 cm 15.9 x 22.8 x 27.9 cm 10.16 x 30.5 x 21.6 cm 30.48 x 21.59 x 10.8 cm 30.5 x 21.6 x 10.8 cm 10.16 x 30.5 x 21.6 cm
(9 x 7 x 3.67 in) (12.0 x 8.5 x 4.38 in) (6 x 12.5 x 11.25 in) (6.3 x 9 x 11 in) (4 x 12 x 8.5 in) (12 x 8.5 x 4.25 in) (12 x 8.5 x 4.25 in) (4 x 12 x 8.5 in)

6.35 x 5.08 x 19.05 cm 6.35 x 5.08 x 19.05 22.9 x 43.2 x 30.5 cm 40.64 x 30.5 x 19.7 cm
– – – –
(2.5 x 2.0 x 7.5 in) (2.5 x 2.0 x 7.5 in) (9 x 17 x 12 in) (16 x 12 x 7.75 in)

1.96 kg (4.32 lbs) – 6.8 kg (15 lbs) 4.5 kg (10 lbs) 4.5 kg (10 lbs) 13.7 kg (30.2 lbs) 6.4 kg (14 lbs) 4.5 kg (10 lbs)

15 23 27 29 16 22 22 16

Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com 5
SYRINGE PUMPS
Choosing the Right Pump for Your Application & Budget
(continued)
SYRINGE PUMPS

Find your application and go to the pages indicated for more information!

Syringe Pump Application Guide


STANDARD SYRINGE PUMPS
Pump 11 Pump 11 Pump 11
Pump 22 Pump 33 PHD 22/2000
Elite Pico Plus Elite Elite Nanomite
Application Guide

SEE PAGE 11 14 15 26 27 29
ACCURATE DELIVERY OF COATINGS X X
ANIMAL FEEDING X X X
BULK FLUID TRANSFER X
CELL CULTURES X X
CELLULAR INJECTION X X X
CONTINUOUS INFUSIONS X
DOPING X X X
DRUG DELIVERY (SAME INFUSION RATES) X X X
DRUG DELIVERY (DIFFERENT INFUSION RATES) X X (RS-232)* X X
DRUG DELIVERY (TIME RELEASED) X
DRUG DEVELOPMENT X X X
ELECTROSPINNING X X
FLUID BLENDING X X (RS-232)* X X (RS-232)*
FLUID BLENDING (2 INDEPENDENT CHANNELS) X
FLUID SAMPLING X X X X X X
GRADIENTS X X (RS-232)* X X (RS-232)*
HIGH PRESSURE INJECTION X
HIGHLY CORROSIVE FLUIDS
HPLC X X X
INJECTING INTO HIGH PRESSURE X
REACTION VESSELS
INJECTION PRESSURE CALCULATIONS X X X
INSTRUMENT INJECTIONS X X X
LOW PRESSURE CHROMATOGRAPHY X
MASS SPECTOMETRY X X X X
MEDICAL COATING DELIVERY
MICRODIALYSIS X X X
MICROFLUIDICS X X X
MRI STUDIES
MULTIPLE SIMULTANEOUS FEEDING STATIONS X X (RS-232)* X (RS-232)*
NANOFLUIDICS X X
NUTRITIONAL STUDIES X X X
OEM MODULES
OOCYTE APPLICATIONS X X
PATCH CLAMPING
REMOTE PUMPING OF HAZARDOUS MATERIAL X X
STEREOTAXIC INJECTIONS X
TITRATIONS X X (RS-232)* X
VISCOUS SOLUTIONS X

*NOTE: Can be done using RS-232 Computer Control

6 Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com
SYRINGE PUMPS
Choosing the Right Pump for Your Application & Budget
(continued)

SYRINGE PUMPS
OEM SYRINGE PUMP MODULES
PHD ULTRA™ PHD ULTRA™ 4400 HIGH
PHD ULTRA™ MRI PHD 22/2000 PHD ULTRA™ HPSI MICROLITER MILLILITER
PUSH/PULL HPSI PRESSURE

Application Guide
16 16 28 22 22 34 34 34
X X X
X
X X
X X
X X X
X X X
X
X
X (RS-232)*
X X
X
X X
X X X X
X X
X X X
X X X
X X X
X X X
X X
X X X

X
X X X X
X
X
X X
X
X
X
X X
X X
X
X X X
X
X
X X X X X X

X X X
X X X X

Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com 7
SYRINGE PUMPS
Application Selection Guide
SYRINGE PUMPS

W ith more than 60 years of experience in the development, manufacture, and support of the
highest quality syringe pumps, and 100 years in fluidics, Harvard Apparatus has a wealth of
experience to share in recommending the right solution for your application. Following is only a
partial guide of some application suggestions. Contact our Technical Support group for their
input or with questions for the best pump to meet your need.
If you do not see what you feel is the best solution for your application, give us a call as we often
develop or modify standard products for particular applications at little or no extra cost.
Application Selection Guide

Neuroscience Infusion and Drug Delivery


Applications in this area include: microdialysis and site specific Delivering accurate volumes and flows is critical to maintaining
microinjection into various brain regions. dosing regimens, interpretation of pharmacokinetics and other data.
• For stereotaxically guided, single channel microinjection, • For single or dual channel infusions, see the Pump 11 Elite
see the Pump 11 Elite Nanomite on page 15, or the PHD on page 11, or PHD ULTRA™ on page 16.
ULTRA™ Nanomite on page 23. • If MRI or PET studies are being conducted, see the PHD
• For single or dual probe microdialysis, see the Pump 11 22/2000 on page 28.
Elite on page 11 or Pico Plus Elite on page 14. • To run multiple studies from a single pump, see the PHD
• For applications using a liquid switch, or for running ULTRA™ on page 16.
multiple experiments simultaneously, see the PHD ULTRA™
on page 16.

Neuroscience References Infusion and Drug Delivery References


PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR PROC SOC PHOTO OPT INSTRUM ENG. 2008; 6854: 68540H.
Volume 89, Issue 1, March 2008, Pages 17-22 doi: 10.1117/12.768798.
J Appl Physiol 106: 1793-1799, 2009.
EUROPEAN JOURNAL OF PHARMACOLOGY
EXPERIMENTAL NEUROLOGY Volume 602, Issue 1, 5 January 2009, Pages 112-116
Volume 210, Issue 2, April 2008, Pages 514-520
ACTA ANAESTHESIOLOGICA SCANDINAVICA
Volume 52, Issue 2, pages 289–294, February 2008

8 Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com
SYRINGE PUMPS
Application Selection Guide (continued)

Cell Biology Mass Spectrometry Calibration

SYRINGE PUMPS
Cellular studies typically involve the injection of very small volumes and Electrospray Ionization
under controlled conditions. Several models offer a foot pedal
Calibration and Electrospray Ionization
accessory to start/stop flow on command.
Where precise volume delivery and pulse free flow are required for
• For cellular microinjections of plasmids, viruses, and the
optimum instrument calibration or solvent elimination, the Pump 11
like, see either the Pump 11 Pico Plus Elite on page 14,
series has long been the industry standard for manufacturers in OEM
PHD ULTRA™ Nanomite on page 23 or the Pump 11 Elite
configurations and end users. See the Pump 11 Elite on page 11,
Nanomite on page 15.
and Pump 11 Pico Plus Elite systems on page 14.

Application Selection Guide


Additionally, use of the gradient capabilities of the Pump 11 Elite or
PHD ULTRA™ Series allows for automated multi-point calibration
when performing GLP studies.

MALDI-TOF Matrix Addition


Using the Nanomite with its detachable delivery and electronics
allows for easy placement of the
syringe over the target to facilitate
the dispensing of the
appropriate
matrix. See the
PHD ULTRA™
Nanomite on
page 23 or the
Pump 11 Elite
Nanomite on page 15.

Cell Biology References


ELECTROPHORESIS
Volume 29, Issue 14, pages 2939–2944, No. 14 July 2008
June 6, 2008 The Journal of Biological Chemistry, 283, 15816-15824
MATERIALS SCIENCE AND ENGINEERING: C
Volume 29, Issue 4, 5 May 2009, Pages 1293-1301

Chemical
and Industrial / Electrospinning
Where chemical synthesis, pressurized systems, and other applications
demand high performance Harvard Apparatus has the right solution.
• For high pressure applications, consider the PHD ULTRA™
HPSI with stainless steel syringes on page 22 or the PHD
ULTRA™ 4400 on page 22.
Harvard Apparatus pumps
are used in creating Nano
and Micro scale polymer Mass Spectrometery Calibration References
fibers in a high voltage
field. The stability of flow JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY
Volume 19, Issue 3, March 2008, Pages 332-343
and flexibility of use, in the
PHD ULTRA series pumps, INTERNATIONAL JOURNAL OF MASS SPECTROMETRY
Volume 283, Issues 1-3, 1 June 2009, Pages 161-168
makes it easy to alter the
variables relating to JOURNAL OF MASS SPECTROMETRY
successful electrospinning. Our pumps include a grounded power Volume 43, Issue 10, pages 1413–1420, October 2008
supply and can be supplied with a grounding strap, which will shunt
any high voltage arcs to ground.

Chemical and Industrial/Electrospinning References


Anal. Chem., 2008, 80 (9), pp 3112–3122
Muhammad Miftahul Munir et al 2008 Nanotechnology 19 145603
Journal of Biomechanics Volume 42, Issue 6, Pages 722-730 (16 April 2009)

Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com 9
SYRINGE PUMPS
Application Selection Guide (continued)
SYRINGE PUMPS

Microfluidics Nano/Micro Liquid Chromatography


The PHD ULTRA™ series and Pump 11 Elite series pumps have the The advanced programming capabilities of the PHD ULTRA™ and the
performance and flow stability required in micro and nanofluidics. Pump 11 Elite Syringe Pumps allow for the easy generation of binary
These pumps can be used to mix flow streams and/or create multiple or ternany gradients at flow rates ranging from 100 nl/min to
parallel flow streams. Another option is the NanoLeader pressure 1.0 ml/min at pressures up to 7,500 PSI. Depending on the number
pump that can push and/or pull fluids using positive or negative air of syringes used, up to one liter of mobile phase may be delivered
pressure, creating the smoothest flow possible. from each pump used.
Application Selection Guide

Microfluidics References
SENSORS AND ACTUATORS B: CHEMICAL
Volume 140, Issue 1, 18 June 2009, Pages 295-303
PNAS March 4, 2008 vol. 105 no. 9 3191-3196
BIOMEDICAL MICRODEVICES
Volume 10, Number 6, 795-805
ANAL. CHEM., 2009, 81 (8), pp 2854–2859

10 Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com
SYRINGE PUMPS
NEW Pump 11 Elite

SYRINGE PUMPS
Pump 11 Elite
The Pump 11 Elite Series is available in Infusion Only or
KEY FEATURES Infusion/Withdrawal Programmable Models with single or dual syringe
Easy to use touch screen and icon interface racks. All Pump 11 Elite syringe pumps have a footswitch input and
USB serial port for computer control. The Infusion/Withdrawal
Outstanding flow performance Programmable models also have RS-485 (or optional RJ-11) ports for
Easily run simple to complex methods without a PC daisy chaining pumps and Digital I/O for external control via an
independent computer or device (see page 13 for more information
Alphanumeric keypad for easy Method naming and recall
on connectivity).
Adjustable linear force up to 35 lbs
Since 1901 Harvard Apparatus has been supporting bioresearch
Upgrade new versions of software remotely fluidics requirements with a key milestone being the introduction of
Legendary reliability – 2 year warranty the first commercial syringe pump for bioresearch in 1956. Since
1956, over 70,000 satisfied syringe pump users around the world
have made Harvard Apparatus syringe pumps the worlds #1 choice.
APPLICATIONS
The Pump 11 Elite Series is a family of accurate, low flow syringe
Microfluidics pumps designed for use in applications including: mass spec
Drug/Nutritional Delivery calibration, drug and nutritional studies, reactor dosing,
electrospinning and more.
Microdialysis
Easy-to-Use Interface
Emulsification
The Pump 11 Elite Syringe Pumps are very easy to use with an LCD
Bioreactors
color touch screen and icon interface. The Message Area of the
Electrospinning touch screen is used to display helpful instructions for the currently
Mass Spectrometry displayed screen. It is also used to display error or warning messages
to indicate problem conditions in a Method or error conditions during
The Pump 11 Elite Series of syringe pumps expands its capabilities to pump operation. The Run Screen shows all of the pump parameters
satisfy your experimental requirements. These compact syringe pumps on one screen for easy review.
carry on the tradition as the premier workhorse infusion pump, offering The software is organized into three main navigational branches, the
unparalleled ease of use with a high resolution color touch screen with quick start Methods, user-defined Methods, and system settings. You
intuitive icon interface. The Pump 11 Elite Series allows you to create, can control operations directly through the touch screen or remotely
save and run simple to complex methods without a PC. from an independent computer or device via the external I/O interface.

Superior Performance
These syringe pumps have a new mechanism that includes a tight
gripping, more secure syringe clamp for syringes ranging from 0.5ul
to 60ml (single syringe) and 0.5µl to 10 ml (dual syringe). The Pump
11 Elite Series offers enhanced flow performance with high accuracy
and smooth flow from 1.28 pl/min to 88.28 ml/min (25.99 ml/min
for dual syringe rack).

Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com 11
SYRINGE PUMPS
NEW Pump 11 Elite (continued)
SYRINGE PUMPS
Pump 11 Elite

Pump Models Alarms


The Pump 11 Elite Syringe Pumps are available in two configurations There are several alarms available on the Model 11 Elite Syringe
designed for different operating environments and varying degrees of Pumps:
operational flexibility.
• End of Run
1. Infusion Only (single and dual syringe models): This model
supports infusion operations at user-defined flow rates and • Near End of Run
with selectable target volume or time values to control the • Power Up
total infusion volume. The Infusion Only models do not • Stall
include programmable, user-defined Methods.
2. Infusion/Withdrawal Programmable (single and dual syringe
Advanced GLP Documentation Features
models): This model supports infuse only, withdraw only, • Download experimental parameter information to PC
infuse/withdraw and withdraw/infuse operations at user-
• Alphanumeric keypad for method naming
defined flow rates and with selectable target volume or time.
This model also allows users to create and store up to two Adjustable Force
user-defined Methods of 50 steps each on the pump.
The maximum linear force of the Pump 11 Elite is 16 kg (35 lbs).
Accessories Depending upon the syringes you are working with and your overall
experimental setup you may want to adjust the amount of force
A full range of accessories are compatible with the Pump 11 Elite
applied to the pusher block. You can select a percentage of the total
including syringe heaters, in-line heaters and coolers, nanofluidic
force from 20% to 100%. Refer to the user’s manual for suggested
circuits, connectors, tubing, syringes and more.
force level settings.
Program Description
To operate the Pump 11 Elite, the user defines all the required
parameters for infusing or withdrawing liquids through a Method. CONTROL MULTIPLE PUMPS VIA
This may be a Quick Start Method, Pre-Programmed or User-Defined
Method. The basic operation is a simple 3-step procedure:
DAISY CHAIN WITH RS-485
1. Select a method
2. Enter operating parameters
3. Preview or Run your method
Quick Start Methods are simple infusions, withdrawals or a
combination (depending upon the model). Custom user-defined
Methods can be created when more advanced programming is
required. The setup for a custom Method is easy using the standard
profiles found on all Infusion/Withdrawal Programmable Elite Models.
The list of available profiles is:
Constant Rate Gradient (binary)
Ramp Autofill

By programming custom (user-defined) Methods into the pump,


multi-user errors are reduced. Easily transfer Methods to other pumps
and/or download Methods from a PC. Forget having to duplicate
Method-development efforts for each new pump added to your system.

12 Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com
SYRINGE PUMPS
NEW Pump 11 Elite (continued)

Advanced Connectivity

SYRINGE PUMPS
The infusion only Pump Syringe 11 Elite Pumps come standard with a
Footswitch input and USB connector. The infusion/withdrawal
programmable Pump 11 Elite Syringe Pumps include a Footswitch input,
USB, RS-485 and I/O connectors. There is also an option for RJ-11
connectors on the programmable pumps. This option has to be ordered at
the time the pump is ordered.

Pump 11 Elite
OPTIONAL
RJ-11
CONNECTORS
(for pump-to-pump
communication)

FOOTSWITCH USB SERIAL RS-485 UNIVERSAL


INPUT INPUT CONNECTORS POWER INPUT
(for communication (for pump-to-pump
USER I/O from PC) communication)
CONNECTOR

Pump 11 Elite Specifications FOOTSWITCH INPUT Start and stop a pump


USB SERIAL INPUT Control your pump with a computer
TYPE Microprocessor single or dual syringe, infusion
RS-485 CONNECTORS Connect multiple pumps together
only or infusion/withdrawal programmable
(daisy chain up to 99 pumps)
ACCURACY ±0.5% Connect satellite pumps to the Master pump for
REPRODUCIBILITY ±0.05% binary gradient system (% composition)
RJ-11 CONNECTORS Connect multiple pumps together (daisy chain)
SYRINGE:
(OPTION)
Type Plastic or glass USER I/O CONNECTOR
Size (single syringe) 0.5 µl to 50/60 ml Direction Set pump to infuse or withdraw
Control Input
Size (dual syringe) 0.5 µl to 10 ml
Trigger Input Connect an external device to start and stop
FLOW RATE: a pump or Method
Single Syringe 1.28 pl/min to 88.28 ml/min Trigger 1 Ouput Signal another device to start and stop a pump or Method
Dual Syringe 1.28 pl/min to 25.99 ml/min Run indicator Connect an external LED or monitoring device to a pump
DISPLAY 4.3" WQVGA TFT color display with touch screen
CONNECTORS:
Order # Product
RS-485 IEEE-1394, 6 position
PC1 70-4500 Pump 11 Elite Infusion Only Single Syringe
USB Type B
I/O & TTL 15 pin D-Sub connector PC1 70-4501 Pump 11 Elite Infusion Only Dual Syringe

Footswitch mini phono jack PC1 70-4504 Pump 11 Elite Infusion/Withdrawal Programmable Single Syringe
AVERAGE LINEAR FORCE 16 kg (35 lbs) @ 100% Force Selection PC1 70-4505 Pump 11 Elite Infusion/Withdrawal Programmable Dual Syringe
STEP RESOLUTION 0.069 µm/µstep
INPUT POWER 12-30 VDC
INPUT POWER CONNECTION 2.5 mm ID x 5.5 mm OD male plug
POWER SUPPLY 100-240 VAC, 50/60 Hz, 8 Watts Universal Power
Supply, Use Only a Harvard Apparatus Approved
Power Supply and Line Cord
DIMENSIONS, H x W x D 22.6 x 17.78 x 15 cm (9 x 7 x 6 in)
WEIGHT 2.1 kg (4.6 lbs)
REGULATORY CERTIFICATIONS CE, ETL (UL, CSA), WEEE, EU RoHS & CB Scheme

Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com 13
SYRINGE PUMPS
NEW Pump 11 Pico Plus Elite
SYRINGE PUMPS
Pump 11 Pico Plus Elite

KEY FEATURES Pump 11 Pico Plus Elite Specifications


Easy to use touch screen and icon interface TYPE Microprocessor dual syringe,
infusion/withdrawal programmable
Outstanding flow performance
ACCURACY ±0.35%
Easily run simple to complex methods without a PC
REPRODUCIBILITY ±0.05%
Alphanumeric keypad for easy Method naming and recall
SYRINGE:
Adjustable linear force up to 35 lbs Type Plastic or glass
Upgrade new versions of software remotely Size Minimum 0.5 µl
Legendary reliability – 2 year warranty Size Maximum 10 ml
FLOW RATE:
APPLICATIONS
Minimum 0.54 pl/min
Microfluidics Maximum 11.70 ml/min
Drug/Nutritional Delivery DISPLAY 4.3" WQVGA TFT color display with touch screen

Microdialysis CONNECTORS:

HPLC RS-485 IEEE-1394, 6 position


USB Type B
Cellular Injections
I/O & TTL 15 pin D-Sub connector
Mass Spectrometry
Footswitch Mini phono jack
AVERAGE LINEAR FORCE 16 kg (35 lbs) @ 100% Force Selection
The Pump 11 Pico Plus Elite is the lowest flow, highest accuracy
syringe pump. It offers enhanced flow performance with high STEP RESOLUTION 0.031 µm/µstep
accuracy and smooth flow from 0.54 pl/min to 11.70 ml/min. This INPUT POWER 12-30 VDC
dual syringe pump offers unparalleled ease of use with a high INPUT POWER CONNECTION 2.5 mm ID x 5.5 mm OD male plug
resolution color touch screen with intuitive icon interface. The Pump
POWER SUPPLY 100-240 VAC, 50/60 Hz, 8 Watts Universal Power
11 Pico Plus Elite allows you to create, save and run simple to Supply, Use Only a Harvard Apparatus Approved
complex methods without a PC. Power Supply and Line Cord
The Pump 11 Pico Plus Elite is a dual syringe Infusion/Withdrawal DIMENSIONS, H x W x D 22.6 x 17.78 x 15 cm (9 x 7 x 6 in)
Programmable Model. It has a footswitch input, USB serial port for WEIGHT 2.1 kg (4.6 lbs)
computer control, RS-485 ports for daisy chaining pumps and Digital
REGULATORY CERTIFICATIONS CE, ETL (UL, CSA), WEEE, EU RoHS & CB Scheme
I/O for external control via an independent computer or device (see
page 13 for more information on connectivity). There is also an
option of daisy chaining pumps through the RS-232 (RJ-11) ports. Order # Product
For more information on the Pump 11 Pico Plus Elite including
features and programming see the Pump 11 Elite on page 11. PC1 70-4506 Pump 11 Pico Plus Elite Infusion/Withdrawal
Programmable Dual Syringe

14 Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com
SYRINGE PUMPS
NEW Pump 11 Elite Nanomite

SYRINGE PUMPS
Pump 11 Elite Nanomite
KEY FEATURES Pump 11 Elite Nanomite Specifications
Easy-to-use LCD color touch screen with GUI interface TYPE Microprocessor single syringe, infusion/withdrawal
programmable
Light weight makes it ideal for hand-held or
stereotaxic injection ACCURACY ±0.5%
REPRODUCIBILITY ±0.05%
Easily program simple to complex Methods without a PC
SYRINGES (MIN./MAX.) 0.5 µl / 1 ml
Create and store up to 2 Methods
FLOW RATE:

APPLICATIONS Minimum 3.66 pl/min


Maximum 3.818 ml/min
Cellular Injections
DISPLAY 4.3" WQVGA TFT color display with touch screen
Drug Delivery
CONNECTORS:
Microinjections RS-485 IEEE-1394, 6 position
Hand-Held Automated Delivery USB Type B
Stereotaxic Injections I/O & TTL 15 pin D-Sub connector
Regenerative Medicine Footswitch mini phono jack
AVERAGE LINEAR FORCE 5 kg (11 lbs) @ 100% force selection
The Pump 11 Elite Nanomite is a single syringe infusion/withdrawal STEP RESOLUTION 0.198 µm/µstep
programmable syringe pump. This pump allows you to create, save INPUT POWER 12-30 VDC
and run simple to complex Methods without a PC. The flow rate
INPUT POWER CONNECTION 2.5 mm ID x 5.5 mm OD male plug
range is 3.66 pl/min to 3.818 ml/min with 11 lbs of adjustable force
POWER SUPPLY 100-240 VAC, 50/60 Hz, 8 Watts Universal Power
across the entire flow rate range.
Supply, Use Only a Harvard Apparatus Approved
The Pump 11 Elite Nanomite has a footswitch input, USB serial port Power Supply and Line Cord
for computer control, RS-485 ports for daisy chaining pumps and DIMENSIONS, H x W x D:
Digital I/O for external control via an independent computer or
Control Box 22.6 x 17.78 x 9.32 cm (9 x 7 x 3.67 in)
device. There is also an option for daisy chaining pumps through the
RS-232 (RJ-11) ports. This option must be ordered at the time the Mechanism 2.5 x 2.0 x 7.5 in (6.35 x 5.08 x 19.05 cm)
pump is ordered. See page 13 for more information on connectivity. WEIGHT 1.96 kg (4.32 lbs)

This pump consists of a control unit, an injection unit, a 6 foot cable REGULATORY CERTIFICATIONS CE, EU RoHS
to connect the two units and a footswitch. For more information on
the Pump 11 Elite Nanomite including features and programming,
see the Pump 11 Elite on page 11. Order # Product
PC1 70-4507 Pump 11 Elite Nanomite Infusion/Withdrawal
Programmable Single Syringe

Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com 15
SYRINGE PUMPS
NEW PHD ULTRA™ Advanced Syringe Pumps
SYRINGE PUMPS
PHD ULTRA™ Advanced Syringe Pumps

KEY FEATURES PHD ULTRA™


New patent pending drive mechanism for unmatched The PHD ULTRA™ is the solution for your most demanding fluidics
smooth flow, accuracy and precision applications. This pump represents the latest technology in syringe
pumps and was developed utilizing the feedback of the world’s
For operation at pl/min to ml/min flow rates
largest population of syringe pump users.
Easily program simple to complex methods without a PC
The PHD ULTRA™ will change the way you think about syringe
Alphanumeric keypad for easy Method naming and recall pumps. There are three major reasons the PHD ULTRA™ is the new
Real and relative time clocks standard for syringe pumps:

Intuitive touch screen and icon interface 1. NEW Patent pending mechanical drive mechanism and
syringe holding mechanics to achieve the highest
Vertical or horizontal orientation performance of any syringe pump.
Adjustable linear force to 75 lbs 2. NEW EZ PRO Software and user interface allow easy
Multi-syringe racks for multi-channel operation or programming of Methods from simple to complex, all
large capacity reservoir without the use of a PC.
– Preprogrammed Methods for simple to complex
Legendary reliability– 2 year warranty
operations that allow you to be up and running with the
touch of a button.
APPLICATIONS
– LCD, high resolution color touch screen for powerful
Microfluidics functionality, yet very easy to use.
Drug/Nutritional Delivery 3. NEW Levels of Versatility
Electrospinning a. Configurations: Standard, push-pull, remote, high
pressure, multi-racks.
Reaction Chamber Addition
b. Connectivity: For USB or RS-232 computer control;
Mass Spec Calibration
RS-485 or optional RJ-11 for daisy chain
Feeding Cells (control multiple pumps).
Low Pressure Chromatography c. Orientation: Horizontal or vertical orientation to optimize
Continuous Flow bench space or to minimize tubing.

Flow Programming Since 1901 Harvard Apparatus has been supporting bioresearch
fluidics requirements beginning with the introduction of the first
Gradients commercial syringe pump for bioresearch in 1956. Since 1956, over
% Composition Step Changes 70,000 satisfied syringe pump users around the world have made
Harvard Apparatus syringe pumps the world’s #1 choice.
Large Flow Deliveries
The PHD ULTRA™ Syringe Pump series is a family of high-accuracy,
I/O Interactive Experiments
easy to use, rugged pumps designed for versatile applications
including mass spectrometry calibration, drug and nutritional studies,
microdialysis, dispensing, chromatography, LC/HPLC and more.

16 Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com
SYRINGE PUMPS
NEW PHD ULTRA™ Advanced Syringe Pumps (continued)

SYRINGE PUMPS
PHD ULTRA™ Advanced Syringe Pumps
Highest Accuracy and Precision Pump Models
The PHD ULTRA™ syringe pump family has a new patent pending The PHD ULTRA™ Pumps are available in three configurations
fluidics drive mechanism which assures ease of use and high designed for different operating environments and varying degrees of
performance, for the smoothest, most accurate flow rates of any operational flexibility.
syringe pump. Flow rates of 1.56 pl/min to 215.8 ml/min are accurate Infusion Only: This model supports infusion operations at user-
within 0.25% and reproducible within 0.05%. A microprocessor- defined flow rates and with selectable target volume or time
controlled, small step angle stepper motor drives a lead screw and values to control the total infusion volume. The Infusion Only
pusher block. Advanced micro-stepping techniques are employed to models do not include programmable, user-defined Methods.
further reduce the step angle to eliminate flow pulsation.
Infusion/Withdrawal: This model supports infuse only,
Maximum Experimental Versatility withdraw only, infuse/withdraw and withdraw/infuse operations
This pump can be oriented vertically or horizontally for optimum at user-defined flow rates and with selectable target volume or
experimental connectivity. This pump comes standard to hold 2 time. Users can create and store one Method up to 800 steps.
syringes, but can be purchased with 3 other syringe racks: 6/10 Infusion/Withdrawal Programmable: This model supports
syringe rack, 4 x 140ml syringe rack and 4 x microliter syringe rack. infuse only, withdraw only, infuse/withdraw and
Syringe racks can be ordered separately. Multi-syringe racks provide withdraw/infuse operations. Users can create and store
multi-channel operation or serve as a large capacity reservoir. multiple Methods of up to 800 steps on the pump.
• The standard 2-syringe rack holds 2 syringes from 0.5 µl to 140 ml
• The 4 x 140 multi-rack holds four 60 ml or 140 ml plastic syringes only
• 6/10 multi-rack will hold up to 10 syringes from 0.5 µl to 20 ml and
up to 6 syringes from 30 ml to 60 ml
• The microliter syringe rack independently holds 4 syringes, from 0.5
µl to 10 ml, enabling syringes of different sizes to run simultaneously.

Easy-to-Use Interface
The PHD ULTRA™ Syringe Pumps are very easy to use with an LCD color
touch screen and icon interface. The Message Area of the touch screen is
used to display helpful instructions for the currently displayed screen. It is
also used to display error or warning messages to indicate problem
conditions in a Method or error conditions during pump operation. The Run
Screen shows all of the pump parameters on one screen for easy review.

Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com 17
SYRINGE PUMPS
NEW PHD ULTRA™ Advanced Syringe Pumps (continued)
SYRINGE PUMPS

FOOTSWITCH INPUT Start and stop a pump


USB AND RS-232 Control your pump with a computer
SERIAL INPUTS

RS-485 CONNECTORS Connect multiple pumps together (up to 99)


Connect remote mechanism
Connect satellite pumps to the Master pump for
binary or ternary gradient system (% composition)
RJ-11 CONNECTORS Connect multiple pumps together (daisy chain)
(OPTION)
PHD ULTRA™ Advanced Syringe Pumps

USER I/O CONNECTOR


Direction Set pump to infuse or withdraw
Control input

Program Description Trigger Input Connect and external device to start or stop a pump
or Method
To operate the PHD ULTRA™, the user defines all the required
Footswitch Input Start and stop a pump
parameters for infusing and/or withdrawing liquids through a Method.
This may be a Quick Start, Pre-Programmed or User-Defined Method. Trigger 1 Ouput Signal another device to start and stop a pump or Method
The basic operation is a simple 3-step procedure: Trigger 2 Output Signal another device to start and stop a pump or Method
1. Select a Method Sync Output Synchronize other devices
2. Enter operating parameters Valve Output External valve control

3. Preview or Run your Method Run Indicator Connect an external LED or monitoring device to a pump

Quick Start Methods are for simple infusions, withdrawals or a ANALOG CONTROL Analog control of the motor speed (0 to 10 v). This option
(OPTIONAL) must be ordered at the same time the pump is ordered.
combination (depending on the pump model). Custom user-defined
Methods can be created when a more advanced Method is required.
The setup for a custom Method is easy using the standard profiles
found on all Infusion/Withdrawal and Infusion/Withdrawal
Programmable PHD ULTRA’s. The list of available profiles are:
Constant Rate Bolus Pulse
Ramp Concentration Autofill
Stepped Gradient
By programming and saving custom Methods in the pump, multi-user
errors are reduced. Easily transfer complex methods to other pumps
and/or download methods from a PC. Forget having to duplicate
method-development efforts for each new pump added to your system. USER
In addition to the advanced pumping profiles listed above, the PHD I/O CONNECTOR
ULTRA™ contains a variety of advanced options allowing the user to
repeat steps, link methods, control valves, external triggers etc.
ANALOG
CONTROL CONNECTOR
(optional)
Advanced Programming Features
Flow Programming: Change the flow with time, volume or a
triggered event as many times as you like.
Bolus: Inject a large volume of drug (or drugs) at once.
The bolus injection can be made in time or volume.
Concentration Delivery: Calibrate flow in concentration units
of mg/kg easily so flow is calibrated to concentration of drug
and animal weight.
Gradients: EZ PRO software allows you to easily program
gradients, continuous or stepped.
% Ratio: Up to three solvents.
I/O: Dedicated and user defined I/O. RS-485
Pulsed Flow: So you can program the pulse easily. CONNECTORS
(for pump-to-pump USB
Advanced Connectivity communication) SERIAL INPUT
(for communication
All PHD ULTRA™ Syringe Pumps come standard with a footswitch, RS-232 SERIAL from PC)
USB, RS-232, RS-485 and I/O connectors. There is also an option CONNECTOR
(for communication FOOTSWITCH
for RJ-11 connectors and analog control. These options have to be from PC) INPUT
ordered at the time the pump is ordered. (switch sold separately)
18 Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com
SYRINGE PUMPS
NEW PHD ULTRA™ Advanced Syringe Pumps (continued)

Alarms Upgrade

SYRINGE PUMPS
There are several alarms available on the PHD ULTRA™ Syringe Pumps. We offer pumps that can be upgraded. If you buy an infusion/withdrawal
End of Run, Near End of Run, Power Up, Stall, Calibration Reminder pump and later decide you want programmability you can upgrade it. You
pay a lot less than buying a whole new pump.
You may chose to activate one, activate them all or mute them all.
Accessories
Advanced GLP Documentation Features
A full range of accessories are compatible with the PHD ULTRA™
• Download experimental parameters to PC
including syringe heaters, in-line heaters and coolers, microfluidic
• Alpha/Numeric capability circuits, connectors, tubing, syringes and more.

PHD ULTRA™ Advanced Syringe Pumps


PHD ULTRA™ Satellite Pumps PHD ULTRA™ Syringe Pump Modules

PHD ULTRA™ Satellite Pumps PHD ULTRA™ Syringe Pump Modules



The NEW PHD ULTRA Satellite Pumps are infusion/withdrawal The NEW PHD ULTRA™ Syringe Pump Modules are dual syringe
pumps. They are available in three configurations: standard, infusion/withdrawal pumps. They are available in three
push/pull and high force. The Satellite Pumps are combined with configurations: standard, push/pull and high force. These modules
stand alone PHD ULTRA™ Pumps to create a Gradient System. include a footswitch input, USB, RS-232, RS-485 and I/O
Satellite Pumps can only be powered from a stand alone PHD connectors. They can be controlled via PC. You can also start and
ULTRA™ via RS-485. They cannot be controlled with a PC. Satellite stop a pump using the 15-pin user I/O connector. See Advanced
Pumps include a footswitch input, USB and RS-485 connectors. See Connectivity on page 18 for more information. See page 20 for part
page 20 for part numbers. numbers.

PHD ULTRA™ Remote Pumps

PHD ULTRA™ Remote Pumps


The NEW PHD ULTRA™ Remote Pumps consist of a
control unit and syringe pumping mechanism all
connected via an RS-485 (IEEE-1394) cable. This
pump includes a 30 foot RS-485 (IEEE-1394)
cable allowing the syringe pumping mechanism and
the control box to be separated. Every version of the
PHD ULTRA™ is available in a remote model. Use
the remote pump in hazardous environments where
the researcher is safer when distanced from the
material being pumped or for applications where it
is necessary to have your pump inside an incubator.
See page 20 for part numbers.

Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com 19
SYRINGE PUMPS
NEW PHD ULTRA™ Advanced Syringe Pumps (continued)
SYRINGE PUMPS

PHD ULTRA™ Specifications Order # Product


TYPE Microprocessor multiple syringe, infusion only, PHD ULTRA™ Options
infusion/withdrawal or infusion/withdrawal
PC1 70-3030 RS-232 RJ-11 Connectors Option (daisy chain)
programmable
PC1 70-3033 Analog Control Input Option (0-10V)3
ACCURACY ±0.25%
PC1 70-3031 Internal Pinch Valve Option 2
REPRODUCIBILITY ±0.05%
PC1 70-3032 Internal 3-Way Isolation Valve Option 2
SYRINGES:
PC1 70-3034 Internal Fan Option4
Type Plastic, glass or stainless steel
PHD ULTRA™ Advanced Syringe Pumps

PHD ULTRA™ Syringe Rack Kits and Upgrades


Size Minimum 0.5 µl
PC1 70-3020 6/10 Multi-Syringe Rack for PHD ULTRA™
Size Maximum 140 ml
PC1 70-3021 4x140 Multi-Syringe Rack for PHD ULTRA™
FLOW RATE:
PC1 70-3022 Microliter Rack, for PHD ULTRA™ holds 4 syringes
Minimum 1.56 pl/min
PC1 70-3023 Anti-Siphon Kit for PHD ULTRA™
Maximum 215.8 ml/min
PC1 70-4010 Upgrade Infusion Only to I/W1
DISPLAY 4.3" WQVGA TFT color display with touchscreen
PC1 70-4011 Upgrade Infusion Only to Programmable1
CONNECTORS:
PC1 70-4012 Upgrade I/W to Programmable1
RS-232 9 pin D-Sub Connector
1 Note: Requires Return to Factory
RS-485 6-position IEEE-1394 2 Note: Only for available for Infusion/Withdrawal or Programmable Models
3 Note: Only for Programmable Models. Not available on Satellite Boxes.
USB Type B
4 Note: Fan option is required if external operating ambient is expected to be >35˚C
I/O & TTL 15 pin D-Sub connector
Accessories
Footswitch Phono jack
PC1 70-4000 RS-485 Cable for Pump-to-Pump Communication, 0.5 m (1.6 ft)
LINEAR FORCE 34 kg (75 lbs) @ 100% force selection
PC1 70-4001 RS-485 Cable for Pump-to-Pump Communication, 2 m (6.6 ft)
STEP RESOLUTION 0.082 µm/step
PC1 70-4020 RS-485 Extension Cable, 9.1 m (30 ft)
VOLTAGE RANGE Universal input 100/240 VAC, 50/60 Hz
PC1 70-4002 USB Cable for PC-to-Pump Communication, 2 m (6.6 ft)
DIMENSIONS, H x W x D 10.16 x 30.48 x 21.59 cm (4 x 12 x 8.5 in)
PC1 70-4003 USB Cable for PC-to-Pump Communication, 5 m (16.4 ft)
WEIGHT 4.5 kg (10 lbs)
PC1 70-4004 RS-232 Cable for PC-to-Pump Communication,
REGULATORY CERTIFICATIONS CE, ETL (UL, CSA), WEEE, EU RoHS
9 pin D-sub, 2 m (6.6 ft)
& CB Scheme
PC1 70-4005 Adapter, PHD Digital I/O
PC1 70-4006 Adapter, D-sub 15 to Term. Blk
Product Order # Order # Order # Order #
PC1 72-8340 Adapter, USB to Serial
PHD ULTRA™ Stand Alone Remote Satellite* Syringe Pump
Standard Module PC1 70-2215 Footswitch (with Phono Plug)
PHD ULTRA™ PC1 55-7002 Auto Fill Valve Box, Normal Pressure, 30 psi
PC1 70-3005 PC1 70-3305 – –
Infusion Only
PC1 55-7008 Auto Fill Valve Box, High Pressure, 200 psi
PHD ULTRA™ PC1 70-3006 PC1 70-3306 PC1 70-3406 PC1 70-3506 PC1 55-7760 Cable Assy, Daisy-chain, Legacy RS-232 RJ-11, 0.6 m (2 ft)
Infusion/Withdrawal
PC1 72-2478 Cable Assy, Daisy-chain, Legacy RS-232 RJ-11, 2.1 m (7 ft)
PHD ULTRA™
Infusion/Withdrawal PC1 70-3007 PC1 70-3307 – – PC1 55-8000 Adapter for 25 ml, 50 ml, 100 ml Hamilton GasTight™ Syringes
Programmable
PHD ULTRA™ Stand Alone Remote Satellite* Syringe Pump
Push/Pull Module
PHD ULTRA™
Push/Pull PC1 70-3008 PC1 70-3308 PC1 70-3408 PC1 70-3508
Infusion/Withdrawl
PHD ULTRA™
Push/Pull PC1 70-3009 PC1 70-3309 PC1 70-3410 –
Infusion/Withdrawl
Programmable
PHD ULTRA™ Stand Alone Remote Satellite* Syringe Pump
High Pressure Module
PHD ULTRA™
4400 Pump I/W PC1 70-3010 PC1 70-3110 PC1 70-3410 PC1 70-3510
Programmable
PHD ULTRA™
Hpsi Remote Pump – PC1 70-3111 – –
I/W Programmable
PHD ULTRA™
Hpsi Remote Pump – PC1 70-3112 – –
I/W Programmable
with 10 x 140 Rack
*Note: Gradient Systems are available, see page 21 for details.

20 Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com
SYRINGE PUMPS
NEW Mixture/Dose Delivery System
PC1 70-4102
PHD ULTRA™
Gradient System

SYRINGE PUMPS
Stepped, Continuous, and Ramped gradient
with Stand

Stepped

Flow Rate
Continuous

Mixture/Dose Delivery System


Ramped

Time

PHD ULTRA™ Specifications


TYPE Microprocessor multiple syringe, infusion only, infusion/
withdrawal or infusion/withdrawal programmable
KEY FEATURES ACCURACY ±0.25%
Easily run binary or ternary gradients without a PC REPRODUCIBILITY ±0.05%
SYRINGES:
Combine multiple flow streams into one common output
Type Plastic, glass or stainless steel
No stopping experiment to fill syringes with different mixtures Size Minimum 0.5 µl
Size Maximum 140 ml
APPLICATIONS FLOW RATE:
Serial Dilutions of reaction dosing solutions Minimum 1.56 pl/min
Maximum 215.8 ml/min
Serial Dilutions for drug infusion experiments
DISPLAY 4.3" WQVGA TFT Color Display with Touchpad
Serial Dilutions for nutritional infusion experiments CONNECTORS:
Serial Dilutions for mixing polymers in electrospinning RS-232 9 pin D-Sub Connector
Chromatography RS-485 6-position IEEE-1394
USB Type B
FIA systems
I/O & TTL 15 pin D-Sub Connector
Footswitch Phono jack
The PHD ULTRA™ Gradient Systems allows you to quickly and easily run
LINEAR FORCE 34 kg (75 lbs) @ 100% force selection
binary or ternary mixtures automatically without a PC. The Method is
STEP RESOLUTION 0.082 µm/step
totally programmed from a master controller pump, so it is easy to
VOLTAGE RANGE Universal input 100/240 VAC, 50/60 Hz
program. The intuitive program interface makes simple to complex
mixing easy. The Gradient Profile is used to combine multiple flow DIMENSIONS, H x W x D 10.16 x 30.48 x 21.59 cm (4 x 12 x 8.5 in)
streams from different pumps into a common output stream. The flow WEIGHT 4.5 kg (10 lbs)
can be smooth and continuous or stepped. No stopping the experiment, CERTIFICATIONS CE, ETL (UL, CSA), WEEE, EU RoHS & CB Scheme
mixing different % volume mixtures and placing new syringes into the
pumps. Push one button and it all happens automatically. Order # Product
Binary and ternary gradient systems are available with or without a stand.
PC1 70-4101 PHD ULTRA™ Gradient System 1 Master/1 Satellite with Stand
Individual Satellite units are also available for purchase separately.
PC1 70-4102 PHD ULTRA™ Gradient System 1 Master/2 Satellites with Stand
For more information on the PHD ULTRA™ Syringe Pumps see page 16.
PC1 70-4106 PHD ULTRA™ Gradient System 1 Master/1 Satellite without Stand
For more information on the PHD ULTRA™ Satellite units see page 19.
PC1 70-4107 PHD ULTRA™ Gradient System 1 Master/2 Satellites without Stand

Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com 21
SYRINGE PUMPS
NEW PHD ULTRA™ HPSI and PHD ULTRA™ 4400
SYRINGE PUMPS

PHD ULTRA™ 4400 Stand-Alone

PHD ULTRA™ HPSI Remote


PHD ULTRA™ HPSI and PHD ULTRA™ 4400

KEY FEATURES KEY FEATURES


Delivers >200 lbs (91 kg) linear pumping force across High capacity – up to 800 ml with four 200 ml syringes
a wide flow rate range
Ultra high pressure – delivers over 400 lbs of pumping force
Accurate and smooth flow
Program simple to complex Methods without a PC
Ideally suited for stainless steel syringes
Built to last – rugged construction for a lifetime of service
Easy-to-use touch screen and icon interface
Accepts only Harvard Apparatus’ stainless steel syringes
Program simple to complex Methods without a PC
Legendary reliability – 2 year warranty
Legendary reliability – 2 year warranty

Specifications PHD ULTRA™ 4400 Stand-Alone PHD ULTRA™ 4400 Remote PHD ULTRA™ HPSI Remote
TYPE Microprocessor single syringe Microprocessor single syringe Microprocessor multiple syringe
infusion/withdrawal programmable infusion/withdrawal programmable infusion/withdrawal programmable
ACCURACY ±0.35% ±0.35% ±0.50%
REPRODUCIBILITY ±0.05% ±0.05% ±0.05%
SYRINGES (MIN./MAX.) 0.5 µl to 140 ml 0.5 µl to 140 ml 20 ml to 200 ml (stainles steel only)
FLOW RATE:
Minimum 3.06 pl/min 3.06 pl/min 50.70 nl/min
Maximum 215.8 ml/min 215.8 ml/min 144.1 ml/min
CONNECTORS:
RS-232 9 pin D-Sub Connector 9 pin D-Sub Connector 9 pin D-Sub Connector
RS-485 IEEE-1394, 6 pos IEEE-1394, 6 pos IEEE-1394, 6 pos
USB Type B Type B Type B
I/O & TTL 15 pin D-Sub Connector 15 pin D-Sub Connector 15 pin D-Sub Connector
AVERAGE LINEAR FORCE 91 kg (200 lbs) @ 100% Force Selection 91 kg (200 lbs) @ 100% Force Selection 197 kg (433 lbs) @ 100% Force Selection
1.8° Stepper Motor 1.8° Stepper Motor 1.8° Stepper Motor
VOLTAGE RANGE 100-240 VAC: 50/60 Hz, 50 W, 0.5 A fuse 100-240 VAC: 50/60 Hz, 75 W, 0.5 A fuse 100-240 VAC: 50/60 Hz, 75 W, 0.5 A fuse
DIMENSIONS, H x W x D:
Control Box 30.48 x 21.59 x 18.4 cm (12 x 8.5 x 7.25 in) 30.5 x 21.6 x 10.8 cm (12 x 8.5 x 4.25 in) 30.48 x 21.59 x 10.8 cm (12 x 8.5 x 4.25 in)
Remote Box N/A 27.9 x 13.5 x 18.4 cm (11.0 x 5.3 x 7.25 in) 40.64 x 30.48 x 19.69 cm (16 x 12 x 7.75 in)
WEIGHT 5.5 kg (12.1 lb) 6.4 kg (14.1 lb) 13.7 kg (30.2 lb)

Order # PC1 70-3010 PC1 70-3110 PC1 70-3111

22 Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com
SYRINGE PUMPS
NEW PHD ULTRA™ Nanomite

Stereotaxic

SYRINGE PUMPS
Mounted Injector
Hand Held

PHD ULTRA™ Nanomite


Control Unit

KEY FEATURES
Light weight makes it ideal for hand-held or stereotaxic injection
PHD ULTRA™ Nanomite Specifications
Easy-to-use LCD color touch screen with GUI interface
TYPE Microprocessor single syringe
Create and store >50 programs for Infusion/Withdrawal Programmable

High performance in a small package ACCURACY ±0.5%


REPRODUCIBILITY ±0.05%
1000 times better than manual syringes
SYRINGES:
APPLICATIONS Type Glass or plastic
Size Minimum 0.5 µl
Cellular Injections
Size Maximum 1 ml
Drug Delivery
FLOW RATE:
Microinjections Minimum 3.66 pl/min
Hand-Held Automated Delivery Maximum 3.818 ml/min
Stereotaxic Injections DISPLAY 4.3" WQVGA TFT color display with touchscreen

Regenerative Medicine CONNECTORS:


RS-232 9 pin D-Sub connector
RS-485 IEEE-1394, 6 position
The PHD ULTRA™ Nanomite is a single syringe infusion/withdrawal
programmable syringe pump. This pump allows you to create, save USB Type B
and run simple to complex Methods without a PC. The flow rate I/O & TTL 15 pin D-Sub connector
range is 3.66 pl/min to 3.818 ml/min with 11 lbs of adjustable force Footswitch Mini phono jack
across the entire flow rate range. AVERAGE LINEAR FORCE 5 kg (11 lbs) @ 100% force selection
The PHD ULTRA™ Nanomite has a footswitch input, RS-232 and USB STEP RESOLUTION 0.198 µm/µstep
serial ports for computer control, RS-485 ports for daisy chaining VOLTAGE RANGE 100-240 VAC, 50/60 Hz, 75 W, 0.5 A fuse
pumps and Digital I/O for external control via an independent computer
DIMENSIONS H x W x D:
or device. There is also an option for daisy chaining pumps through the
RS-232 (RJ-11) ports. This option must be ordered at the time the Control Box 30.5 x 21. 6 x 11.1 cm (12.0 x 8.5 x 4.38 in)
pump is ordered. See page 18 for more information on connectivity. Injector Unit 6.35 x 5.08 x 19.05 cm (2.5 x 2.0 x 7.5 in)

This pump consists of a control unit, an injection unit, a 6 foot cable WEIGHT:
to connect the two units and a footswitch. Control Box 2.06 kg (4.55 lbs)

For more information on the PHD ULTRA™


Nanomite including Injector Unit 0.458 kg (1.01 lbs)
features and programming see the PHD ULTRA™ on page 16. REGULATORY CERTIFICATIONS CE, EU RoHS

Order # Product
PC1 70-3601 PHD ULTRA™ Nanomite Infusion/Withdrawal Programmable
Single Syringe

Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com 23
SYRINGE PUMPS
NEW NanoCool™ Injector
NanoCool Hand-held
or Stereotaxic
SYRINGE PUMPS

Mounted Injector
NanoCool™ Injector

Control Unit
Footswitch

KEY FEATURES Temperature Effect on O2 Consumption by Organ Cell Type


18ºC for optimal cell viability on any delivery syringe Oxygen Change in O2
and eppendorf Organ Temperature Comsuption Consumption % Change

20% Increase in Survivability, 76% Lower O2 Consumption Kidney 37 to 18 3.7 to 0.9 2.8 75.7
Rate at 18ºC vs. 37ºC Liver 37 to 18 3.0 to 0.6 2.4 80

Flow ramping to reduce injection site blowback Heart 37 to 18 2.4 to 0.7 1.7 70.8

Programmed methods for automatic recall of entire Brain 37 to 18 1.9 to 0.4 1.5 78.9
cell delivery system. Up to 100 methods stored for recall Muscle 37 to 18) 0.8 to 0.2 0.6 75

2 year warranty Skin 37 to 18 0.4 to 0.1 0.3 75

High accuracy delivery between 367.4 pl/min to 1.906 ml/min


Preprogrammed bolus injection mode,
just specify injection size and time of dispense
Footswitch activation keeps hands free
IR Temperature Image
NanoCool at 18°C
NanoCool™ Cell Delivery System
When injecting stem cells viability of cells can be a major issue. The
Harvard Apparatus NanoCool is the only cooled cell injection system
with optional cooled and oxygenated vortex mixer. The injection
system and sample vortex holder are held at 18ºC. The cell delivery is
totally integrated in it operation through the NanoCool’s
microprocessor system: power, temperature injection volumes and
flow ramping are all controlled by the NanoCool’s program. Keeping NanoCool™ Injector Specifications
the cells at 18ºC instead of 37ºC reduces O2 consumption of cells by ACCURACY ±0.5%
an average of 76%. The chart to the right shows the different organ REPRODUCIBILITY ±0.05%
utilization curves.
SYRINGES (MIN./MAX.) 50 µl / 500 µl
FLOW RATE:
Minimum 367.4 pl/min
Maximum 1.906 ml/min
INJECTOR HEAD/ACTUATOR, 20.3 x 5.1 x 5.1 cm (8 x 2 x 2 in)
LxHxW

Order # Product
PC1 70-3040 NanoCool™ Injector

24 Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com
SYRINGE PUMPS
Pump 11 Plus

SYRINGE PUMPS
PC1 70-2209
Dual Syringe

Pump 11 Plus
PC1 70-2208
Single Syringe

KEY FEATURES Pump 11 Plus Specifications


Small footprint TYPE Microprocessor single or dual syringe, infusion only or
infusion/withdrawal
RS-232 option for computer control
ACCURACY ±0.5%
Legendary reliability – 2 year warranty
REPRODUCIBILITY ±0.1%

APPLICATIONS SYRINGE:

Drug/Nutritional Delivery Type Plastic or glass


Size (single syringe) 0.5 µl to 50/60 ml
Microfluidics/Nanofludics
Size (dual syringe) 0.5 µl to 10 ml
Electrospinning
FLOW RATE:
Mass Spec Calibration Single Syringe 0.0014 µl/hr to 26.56 ml/min
Microdialysis Dual Syringe 0.0014 µl/hr to 7.91 ml/min
CONNECTORS:
Pump 11 Plus
RS-232 Advanced models only
Harvard Apparatus’ Pump 11 Plus is a high performance smooth flow
TTL No
syringe pump at a basic syringe pump price!
AVERAGE LINEAR FORCE 7.27 kg (16 lbs)
Bright Display and Easy-To-Use Interface STEP RESOLUTION 0.33 µm/step
A two-line 16 character vacuum fluorescent display and six VOLTAGE RANGE Universal input 100/240 VAC, 50/60 Hz, 18 watts (Use
membrane keypad make this a powerful, easy-to-use syringe pump. (POWER SUPPLY) only Harvard Apparatus approved supply and line cord)
Only two entries are required to start pumping; syringe Inside
DIMENSIONS, H x W x D 13 x 22.9 x 11.4 cm (5 x 9 x 4.5 in)
Diameter (mm) and flow rate. The flow rate can be changed while the
WEIGHT 2.1 kg (4.6 lb)
pump is running.

Two Modes of Operation, Constant Flow Rate & Volume Dispense


Order # Product
The Pump 11 Plus will operate continuously in RATE mode or
accurately dispense a specific amount of fluid in VOLUME mode. PC1 70-2208 Pump 11 Plus Infusion Only Single Syringe
PC1 70-2209 Pump 11 Plus Infusion Only Dual Syringe
Versatile
PC1 70-2211 Pump 11 Plus Advanced Infusion/Withdrawal
Select from two different models, Infusion Only or Infusion/Withdrawal. Single Syringe with Dual RS-232
Both models are available with either a single syringe or dual syringe PC1 70-2212 Pump 11 Plus Advanced Infusion/Withdrawal
configuration. Dual Syringe with Dual RS-232

References
Miguéns, M., et al., Glutamate and aspartate levels in the nucleus accumbens during
cocaine self-administration and extinction: a time course microdialysis study,
Psychopharmacology, 2008, Vol. 196, 303–313
Russom, A., et al., Microfluidic Leukocyte Isolation for Gene Expression Analysis in
Critically Ill Hospitalized Patients, Clinical Chemistry, 2008, Vol. 54:5, 891–900
Choi, S. and Park, J., Microfluidic system for dielectrophoretic separation based on a
trapezoidal electrode array, Lab on a Chip, 2005, Vol. 5, 1161–1167
Tan, YC., Li Ho, Y., and Phillip, A., Microfluidic sorting of droplets by size, Microfluid
Nanofluid, 2008, Vol. 4, 343–348
Cucchiaro, G., Chaijale, N., and Commons, K.G., The locus coeruleus nucleus as a site of
action of the antinociceptive and behavioral effects of the nicotinic receptor agonist,
epibatidine, Neuropharmacology, 2006, Vol. 50, 769-776

Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com 25
SYRINGE PUMPS
Pump 22 and Physio 22 Multiple Syringe Pumps

Syringe Pump 22, but with a special transformer designed for minimum
SYRINGE PUMPS

RFI (Radio Frequency Interference). This new transformer cuts electrical


noise so that it is almost non existent. With the PHYSIO 22, even the
most sensitive sensors will not show a noise spike.

Pump 22 & Physio 22 Specifications


TYPE Microprocessor multiple syringe,
infusion only or infusion/withdrawal
Pump 22 and Physio 22 Multiple Syringe Pumps

ACCURACY ±0.35%
REPRODUCIBILITY ±0.05%
SYRINGE:
Type Plastic, glass or stainless steel
Size Minimum 0.5 µl
KEY FEATURES
Size Maximum 140 ml
Smooth and accurate flow
FLOW RATE:
Easy to use Minimum 0.002 µl/hr
Versatile with wide flow rate range Maximum 55.1 ml/min
Multi-syringe racks for large reservoir capacity CONNECTORS:

Legendary reliability – 2 year warranty RS-232 25-pin connector


TTL Shared port with RS-232
APPLICATIONS AVERAGE LINEAR FORCE 21.36 (47 lbs)

Drug/Nutritional Delivery STEP RESOLUTION 0.33 µm/step


VOLTAGE RANGE 95 to 130 VAC, 60 Hz; 220 to 260 VAC, 50 Hz, selectable
Fluid Sampling
DIMENSIONS, H x W x D 28 x 22.2 x 14 cm (11 x 8.75 x 5.5 in)
Mass Spectrometry
WEIGHT 4.5 kg (10 lb)

Pump 22
The Harvard 22 Syringe Pump is the pump that set the industry Order # Product
standard! It is the world’s most popular syringe pump. Harvard
PC1 55-2222 Pump 22 Infusion Only with Standard 2-Syringe Rack
Apparatus’ long-standing tradition of providing rugged and reliable
products is the foundation upon which this pump was built. PC1 55-2275 Pump 22 Infusion Only with Anti-Siphon
Standard 2-Syringe Rack*
• The standard 2-syringe rack holds 2 syringes from 0.5 µl to 140 ml
PC1 55-5920 Pump 22 Infusion Only with 6/10 Multi-Syringe Rack
• The 4 x 140 multi-rack holds four 60 ml or 140 ml plastic syringes only
PC1 55-2314 Pump 22 Infusion Only with 4 x 140 Multi-Syringe Rack
• 6/10 multi-rack will hold up to 10 syringes from 0.5 µl to 20 ml and
PC1 55-4150 Pump 22 Infusion Only with Microliter Rack
up to 6 syringes from 30 ml to 60 ml
PC1 55-2226 Pump 22 Infusion/Withdrawal with Standard 2-Syringe Rack
• The microliter syringe rack independently holds 4 microliter sy-
ringes, from 0.5 µl to 10 ml, enabling syringes of different sizes to PC1 55-2219 Pump 22 Infusion/Withdrawal with 6/10 Multi-Syringe Rack
run simultaneously. PC1 55-2316 Pump 22 Infusion/Withdrawal with 4 x 140 Multi-Syringe Rack
This pump features an LED display and numeric keypad for easy entry PC1 55-4153 Pump 22 Infusion/Withdrawal with Microliter Rack
of syringe diameter data and flow rates. Flow rate units can be set in PC1 70-2222 PHYSIO 22 Infusion Only with Standard 2-Syringe Rack
µl/hr, µl/min, ml/hr and ml/min. An optical encoder monitors leadscrew PC1 70-2223 PHYSIO 22 Infusion Only with 6/10 Multi-Syringe Rack
rotation to accurately maintain any flow rate. The run LED flashes when
* Note: Anti-Siphon syringe holder secures syringe plunger to pusher block to
syringe plunger movement stops unexpectedly. A complete line of prevent unintended loss of fluid
accessories for the Pump 22 are available including a footswitch,
audible alarm, reversing switch and serial cables, see page 42. References
The Pump 22 can be controlled using RS-232 (serial) commands. Svoboda, K., et al., Conformation and elasticity of the isolated red blood cell membrane
Multiple syringe pumps can be interconnected by daisy chaining skeleton, Biophys. J., 1992, Vol 63, 784-793.
pumps. Up to 100 pumps can be addressed independently using Jang, IK., Differential Sensitivity of Erythrocyte-Rich and Platelet-Rich Arterial Thrombi to
Lysis With Recombinant Tissue-Type Plasminogen Activator: A Possible Explanation for
internal reference addresses from 0 to 99. The default setting is 0. Resistance to Coronary Thrombolysis, Circulation, 1989, Vol. 79, 920-928.
A set of sample programs, using the basic programming language, is Gao, J., et al., Integrated Microfluidic System Enabling Protein Digestion, Peptide Separa-
included with each pump. tion, and Protein Identification, Anal. Chem., 2001, Vol. 73, 2648-2655
Jayawickrama, D.A., Wolters, A.M. and Sweedler, J.V., Mobile phase compensation to im-
PHYSIO 22 prove NMR spectral properties during solvent gradients, Analyst, 2003, Vol. 128, 421–426
The PHYSIO 22 Pump delivers high accuracy, pulseless flow with no Hiramatsu, M., et al., Reversion of muscarinic autoreceptor agonist-induced acetyl-
choline decrease and learning impairment by dynorphin A (1-13), an endogenous k-opioid
electrical noise to interfere with the sensor signal while performing receptor agonist, British Journal of Pharmacology, 1998, Vol. 123, 920-926
physiological analyses. This specialty pump is based on our legendary

26 Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com
SYRINGE PUMPS
Pump 33 Dual Syringe Pump

SYRINGE PUMPS
Pump 33 Dual Syringe Pump
KEY FEATURES
Pump 33 Specifications
Two independent pumping channels
TYPE Microprocessor dual drive, single syringe,
2 syringes can run in the same or opposite direction, infusion/withdrawal
simultaneously ACCURACY ±0.35%
Program different flow rates for each syringe REPRODUCIBILITY ±0.1%
Legendary reliability – 2 year warranty SYRINGE:
Type Plastic, glass or stainless steel
BENEFITS Size Minimum 0.5 µl
Bulk Fluid Injections Size Maximum 140 ml

Drug Delivery FLOW RATE:

Fluid Sampling Minimum 0.0004 µl/hr


Maximum 106.6 ml/min
Gradients
CONNECTORS:
Continuous Infusion
RS-232 RJ11-4 conductor

The Harvard 33 Dual Syringe Pump is a breakthrough in pumping TTL 9-pin connector
technology. The 33 has two independent pumping channels linked AVERAGE LINEAR FORCE 57 lbs
through hardware and software. When combined with a valve box STEP RESOLUTION 0.33 µm/step
(page 42), it provides the continuous delivery of a peristaltic or piston
VOLTAGE RANGE 95 to 130 VAC, 60 Hz; 220 to 260 VAC, 50 Hz, selectable
pump with the accuracy, absence of pulsation and low flow rates of a
syringe pump. DIMENSIONS, H x W x D 15.2 x 31.1 x 28.6 cm (6 x 12.5 x 11.25 in)
WEIGHT 6.8 kg (15 lb)
Several modes of operation are available to accommodate a range of
setups and experimental protocols. A unique movable limit switch
mechanism is used to change direction or stop operation of the pump
depending on the mode of operation.
Order # Product

Reciprocal/Parallel Mode - Syringe mechanisms can run in the same or PC1 55-3333 Pump 33 Infusion/Withdrawal Dual Syringe
opposite directions (i.e. both infusing or withdrawing at the same time
or one infusing and the other withdrawing) References
Chen, D., Wendt, C.H. and Pui, Y.H.D., A novel approach for introducing bio-materials into
Proportional Mode - Different flow rates and syringe diameters can be cells, Journal of Nanoparticle Research, 2000, Vol 2, 133–139
set for each syringe mechanism Cabrales, P., et al., Oxygen transport by low and normal oxygen affinity hemoglobin
vesicles in extreme hemodilution, Am. J. Physiol. Heart Circ. Physiol., 2005, Vol. 288,
AutoStop Mode - Pump stops operation when a limit switch is activated.
H1885–H1892.
Continuous Run Mode - When a limit switch is activated each syringe .Lee, S.H., et al., A polymer lab-on-a-chip for reverse transcription (RT)-PCR based
mechanism reverses direction. point-of-care clinical diagnostics, Lab on a Chip, 2008, Vol. 8, 2121–2127

This pump has high pressure capability, TTL and RS-232 interface for
data acquisition and computer control. The communication ports
enable daisy-chaining of up to 100 pumps.

Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com 27
SYRINGE PUMPS
PHD 22/2000 MRI Compatible Syringe Pump
SYRINGE PUMPS
PHD 22/2000 MRI Compatible Syringe Pump

Syringe Holder

Control Box

KEY FEATURES PHD 22/2000 Specifications


High accuracy and precision TYPE Microprocessor dual syringe, infusion/withdrawal or
infusion/withdrawal programmable
Can be placed near an imaging magnet
ACCURACY ±0.35%
Holds 0.5 µl to 140 ml glass or plastic syringes
REPRODUCIBILITY ±0.05%
Legendary reliability – 2 year warranty
SYRINGE:
Type Plastic or glass
BENEFITS
Size Minimum 0.5 µl
Injecting Anesthesia
Size Maximum 140 ml
Drug Delivery FLOW RATE:
Injecting Dyes Minimum 0.0001 µl/hr
Maximum 220.82 ml/min
The MRI Compatible Pump is based on the design of one of our most CONNECTORS:
tried and trusted syringe pumps. The PHD 22/2000. This pump is made
RS-232 RJ11-4 conductor
of mostly non-magnetic materials and can be placed near to an imaging
magnet when it is in use! The control box should be positioned at least 5 TTL 9 pin D-Sub. Connector
feet away from the opening of the magnet and not in direct line of the AVERAGE LINEAR FORCE 50 lbs
opening. The exact distance is dependent upon the strength of the STEP RESOLUTION 0.082 µm/step
magnet. This will now make drug or dye perfusions possible while the
VOLTAGE RANGE Universal input 100/240 VAC, 50/60 Hz
magnet is on. This pump is a remote model where the syringe pumping
CABLE LENGTH 9.1 m (30 ft)
mechanism is separated from the control box by a 30 foot cable. This
allows the pump to be started and stopped near the magnet, via a DIMENSIONS, H x W x D:
RUN/STOP switch that was added to the syringe holder. If additional Control Box 9.5 x 27.9 x 22.9 cm (3.75 x 11 x 9 in)
space is required between the control box and pumping mechanism, a Syringe Holder 22.9 x 43.2 x 30.5 cm (9 x 17 x 12 in)
60 foot cable is also available. For more details on the PHD 22/2000
Pump Line, see pages 29 to 30.

Program Description Order # Product


The programming functions of this pump provide powerful PC1 70-2130 PHD 22/2000 MRI Compatible Remote Infusion/Withdrawal
capabilities for advanced experiments. While in program mode this Dual Syringe
pump can perform the following tasks at a predetermined time or PC1 70-2131 PHD 22/2000 MRI Compatible Remote Infusion/Withdrawal
when prompted by a signal from an external device: Programmable Dual Syringe

• Start or stop pumping


• Change pumping direction (infusion/withdrawal)
• Change flow rates
• Pump a precise volume and stop
• Pause operation
• Ramp up or down flow rates
In program mode the above tasks can be linked together into powerful
programs to simplify your automation projects.

28 Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com
SYRINGE PUMPS
PHD 22/2000 Advanced Syringe Pumps
PHD 22/2000
Infusion/Withdrawal PHD 22/2000
with Standard Push/Pull Syringe Pump

SYRINGE PUMPS
2-Syringe-Rack

PHD 22/2000 Advanced Syringe Pumps


PHD 22/2000
Infusion/Withdrawal
with 6/10 Multi-Rack
PHD 22/2000
Infusion Only
with Standard PC1 61-0270
2-Syringe Rack Continuous Flow Tubing Segment

KEY FEATURES PHD 22/2000 Specifications


High accuracy and precision TYPE Microprocessor, multiple syringe, infusion only,
Multiple configuration available infusion/withdrawal or infusion/withdrawal
programmable
Smooth flow over a wide flow rate range
ACCURACY ±0.35%
Multi-syringe racks for large capacity reservoir REPRODUCIBILITY ±0.05%
Legendary reliability – 2 year warranty SYRINGE:
Type Plastic, glass or stainless steel
APPLICATIONS
Size Minimum 0.5 µl
Drug/Nutritional Delivery Size Maximum 140 ml (30 ml for push/pull models)*
Electrospinning FLOW RATE:

Microfluidics/Nanofluidics Minimum 0.0001 µl/hr


Maximum 220.82 ml/min
Mass Spec Calibration
NON VOLATILE MEMORY Stores all settings

Over forty years ago Harvard Apparatus perfected the leadscrew CONNECTORS:
principle and created the first syringe pump. Since that time, tens of RS-232 RJ11-4 conductor
thousands of Harvard Apparatus pumps have earned a reputation as TTL 9 pin D-Sub Connector
the most reliable research pumps in every major laboratory in the
AVERAGE LINEAR FORCE:
World. The PHD 22/2000 syringe pump series gives you the lowest
flow rates, the highest accuracy, the smoothest flow, advanced Standard 50 lbs
programmability from the keypad and yet, is very easy to use. It is High Pressure 66 lbs
also incredibly quiet so it won’t disturb your experimental subjects. POWER 65 W, 0.5 A fuse

Configurations VOLTAGE RANGE Universal input 100/240 VAC; 50/60 Hz

This pump is available as a standard, push/pull, remote, high CABLE LENGTH 9.1 m (30 ft) for remote models only
pressure, or with multi-racks. DIMENSIONS, H x W x D 15.9 x 22.8 x 27.9 cm (6.3 x 9 x 11 in)
WEIGHT 4.5 kg (10 lb)
Upgrade
*Push/Pull pump can hold syringes up to 140 ml if full stroke is not required.
We offer pumps that can be upgraded. If you buy an infusion/ Larger syringes will not fully infuse or withdraw.
withdrawal pump and later decide you want programmability you
can upgrade it, see page 30. References
Mazutis, L., et al., Droplet-Based Microfluidic Systems for High-Throughput Single DNA
Molecule Isothermal Amplification and Analysis, Anal. Chem., 2009, Vol. 81, 4813-4821
Yeoma, J., et al., Microfabrication and characterization of a silicon-based millimeter
scale, PEM fuel cell operating with hydrogen, methanol, or formic acid, Sensors and Ac-
tuators, 2005, Vol. B107, 882-891.
Guillot, P., et al., Towards a continuous microfluidic rheometer, Microfluid Nanofluid, 2008,
Vol. 5, 619-630.
Utada, A.S., et al., Monodisperse Double Emulsions Generated from a Microcapillary
Device, Science, 2005, Vol. 308, 537.
Liu Tsang, V., et al., Fabrication of 3D hepatic tissues by additive photopatterning of
cellular hydrogels, FASEB Journal, 2007, Vol. 21, 790-801.

Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com 29
SYRINGE PUMPS
PHD 22/2000 Advanced Syringe Pumps
(continued)
SYRINGE PUMPS

PHD 22/2000 Syringe Pumps


Infusion Only* Infusion/Withdrawal Programmable
SYRINGE PUMP VERSIONS Standard Force High Force Standard Force High Force Standard Force High Force
Standard Syringe Pumps
STANDARD 2-SYRINGE PC1 70-2000 PC1 71-2000 PC1 70-2001 PC1 71-2001 PC1 70-2002 PC1 71-2002
6/10 MULTI-RACK PC1 70-2003 PC1 71-2003 PC1 70-2006 PC1 71-2006 PC1 70-2009 PC1 71-2009
4 X 140 MULTI-RACK PC1 70-2004 PC1 71-2004 PC1 70-2007 PC1 71-2007 PC1 70-2010 PC1 71-2010
PHD 22/2000 Advanced Syringe Pumps

MICROLITER RACK PC1 70-2005 PC1 71-2005 PC1 70-2008 PC1 71-2008 PC1 70-2011 PC1 71-2011
Remote Syringe Pumps
STANDARD 2 SYRINGE PC1 70-2100 PC1 71-2100 PC1 70-2101 PC1 71-2101 PC1 70-2102 PC1 71-2102
6/10 MULTI-RACK PC1 70-2103 PC1 71-2103 PC1 70-2106 PC1 71-2106 PC1 70-2109 PC1 71-2109
4 X 140 MULTI-RACK PC1 70-2104 PC1 71-2104 PC1 70-2107 PC1 71-2107 PC1 70-2110 PC1 71-2110
MICROLITER RACK PC1 70-2105 PC1 71-2105 PC1 70-2108 PC1 71-2108 PC1 70-2111 PC1 71-2111
Push/Pull Syringe Pumps
STANDARD – – PC1 70-2020 PC1 71-2020 PC1 70-2019 PC1 71-2019
REMOTE – – PC1 70-2120 PC1 71-2120 PC1 70-2119 PC1 71-2119
*Infusion Only models do not include an anti-siphon bracket or a retaining bracket. These can be ordered as a special.

Harvard PHD 22/2000 Pump Series Kits & Upgrades Continuous Flow Tubing Segment
ORDER # PRODUCT This continuous flow tubing segment is used with the PHD 22/2000
Syringe Rack Kits1 Push/Pull Syringe Pump. When used with the programmable model it
makes continuous 24/7 flow possible.
PC1 70-2012 PHD 22/2000 6/10 Multi Syringe Rack
PC1 70-2013 PHD 22/2000 4 x 140 Multi Syringe Rack
PC1 70-2014 PHD 22/2000 Microliter Multi Syringe Rack Tubing Segment Specifications
PC1 70-2015 PHD 22/2000 Anti-Siphon Kit (Infusion Only Pump) TUBING 0.062 in. ID Tygon® tubing
2
Upgrades TUBING LENGTH 3 x 112 in. sections
PC1 70-2016 PHD 22/2000 Infusion Only to Infusion/Withdrawal MAX. PRESSURE 15 p.s.i.
PC1 70-2017 PHD 22/2000 Infusion/Withdrawal to Programmable VALVE MATERIALS Polycarbonate, silicone
PC1 70-2018 PHD 22/2000 Infusion Only to Programmable
1 These multiple syringe racks will fit any PHD 22/2000 series syringe pump listed
above and are easily interchangeable. Order # Product
2 Upgrades are available for Infusion Only and Infusion/Withdrawal models of
PHD 22/2000 series pumps. All upgrades must be factory installed. PC1 61-0270 Continuous Flow Tubing Segment

Remote Extension Cables Syringe Racks


Replacement cables for PHD 22/2000 remote syringe pumps The PHD 22/2000 is offered with a variety of syringe racks to meet
including the PHD 22/2000 Hpsi, see page 31, are available in 5ft your specific application. Multi-syringe racks provide multi-channel
and 30ft lengths. These cables can also be used to increase or operation or serve as a large capacity reservoir.
decrease the distance between the syringe pumping mechanism and
• The push/pull syringe pump holds 4 syringes, 2 in each
the control box.
direction, for syringe sizes 0.5 µl to 30 ml

Order # Product • The standard 2-syringe rack holds 2 syringes from 0.5 µl
or 140 ml
PC1 72-0199 Remote Extension Cable, 1.5 m (5 ft)
• The 4 x 140 multi-rack holds four 60 ml glass or four
PC1 72-1405 Remote Extension Cable, 9.1 m (30 ft)
140 ml plastic syringes only
• 6/10 multi-rack will hold up to 10 syringes from 0.5 µl
to 20 ml and up to 6 syringes from 30 ml to 60 ml
• The microliter syringe rack independently holds
4 microliter syringes, from 0.5 µl to 10 ml, enabling
syringes of different sizes to run simultaneously

30 Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com
SYRINGE PUMPS
PHD 22/2000 Hpsi and PHD 4400 Hpsi High Volume
& Pressure Programmable Syringe Pumps

SYRINGE PUMPS
PHD 22/2000 Hpsi PHD 4400 Hpsi Programmable
with four 200 ml
Stainless Steel Syringes
(syringes not included)

PHD 22/2000 Hpsi and PHD 4400 Hpsi High Volume & Pressure Programmable Syringe Pumps
KEY FEATURES KEY FEATURES
Pump up to 800 ml with four 200 ml syringes Accurate and smooth flow
High accuracy and reproducibility Easy-to-use interface
Rugged construction for a lifetime of service RS-232 serial port for computer control
Accepts only Harvard Apparatus stainless steel syringes Delivers over 200lbs of pumping force across a wide flow rate range
Legendary reliability – 2 year warranty Legendary reliability – 2 year warranty

APPLICATIONS APPLICATIONS
High Pressure Injections High Pressure Injections
Drug Delivery Drug Delivery
Pumping Highly Corrosive Fluids Pumping Highly Corrosive Fluids
Injecting into High Pressure Reaction Vessels Injecting into High Pressure Reaction Vessels

PHD 22/2000 Hpsi Specifications PHD 4400 Hpsi Specifications


TYPE Microprocessor multiple syringe,
TYPE Microprocessor single syringe,
infusion/withdrawal programmable
infusion/withdrawal programmable
ACCURACY ±0.5%
ACCURACY ±0.35%
REPRODUCIBILITY ±0.05%
REPRODUCIBILITY ±0.05%
SYRINGES (MIN/MAX) Holds 20 to 200 ml stainless steel syringes
SYRINGE:
FLOW RATE:
Type Stainless steel**
Minimum 1.5 µl/hr
Size Minimum 2.5 ml
Maximum 112 ml/min
Size Maximum 100 ml
RS-232 RJ11-4 conductor
FLOW RATE:
TTL 9 pin D-Sub. Connector
Minimum 0.0076 µl/min
AVERAGE LINEAR FORCE 197 kg (433 lbs)
Maximum 182.40 ml/min
STEP RESOLUTION 0.0397 µm/step
RS-232 RJ-11 4-conductor
VOLTAGE RANGE Universal input 100/240 VAC, 50/60 Hz
TTL 9-pin D-sub connector
CABLE LENGTH 152 cm (5 ft) approx.
AVERAGE LINEAR FORCE 91 kg (>200 lbs)**
DIMENSIONS, H x W x D:
STEP RESOLUTION 0.082 µm/step
Control Box 9.5 x 27.9 x 22.9 cm (3.75 x 11 x 9 in)
VOLTAGE RANGE Universal input 100/240 VAC, 50/60 Hz
Syringe Holder 22.9 x 43.2 x 30.5 cm (9 x 17 x 12 in)
DIMENSIONS, H x W x D 17 x 23 x 29 cm (6.7 x 9.0 x 11.4 in)
WEIGHT 6.4 kg (14 lbs)
Order # Product REMOTE CABLE 9.1 m (30 ft) Length
PC1 70-2023 PHD 22/2000 Hpsi Programmable Syringe Pump ** Plastic and glass syringes are not recommended because of high force.
PC1 72-0199 Remote Extension Cable, 1.5 m (5 ft)
PC1 72-1405 Remote Extension Cable, 9.1 m (30 ft) Order # Product
PC1 70-2022 RS-232 D-Sub 9 Pin to RJ11-4 Connection Cable PC1 70-2200 PHD 4400 Hpsi Programmable Single Syringe Pump
PC1 70-2201 PHD 4400 Hpsi Remote Programmable Single Syringe Pump

Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com 31
SYRINGE PUMPS
NEW MFRP10 Syringe Pump
SYRINGE PUMPS
MFRP10 Syringe Pump

KEY FEATURES MFRP10 Syringe Pump Specifications


Occlusion alarm ACCURACY ±3% (excluding syringe variations)

Automatic syringe size detection FLOW RATE 0.01 ml/hr – 3 l/hr (dependent on syringe size)

Backup battery COMPATIBLE SYRINGES:


Becton Dickinson 1, 3, 5, 10, 20, 30, 50/60 ml
Unique clutch for one-handed loading of syringes
Monoject 1, 3, 6, 12, 20, 35, 60, 140 ml
Terumo 1, 3, 5, 10, 20, 30, 60 ml
The MFRP10 Syringe Pump is a state-of-the-art infusion pump
B-D Glass 1, 2.5, 5, 10 ml
originally designed for human use in intensive care units and
anesthesia. It is now sold for laboratory animal use only. This pump POWER AC power or DC internal rechargeable
can provide continuous or bolus infusion. RECHARGE TIME < 8 hours
BATTERY CAPACITY Approximately 12 hours
USER SETTINGS Audio Volume Alarm: LOW, NORM, or HIGH
“Snooze” Alarm Delay: 2 to 60 minutes,
Plunger Force: LOW, NORM, or HIGH
ALARMS/ALERTS Battery status; Occlusion; Bolus delivery; Check
clutch; Syringe status; Syringe size invalid; Plunger;
Invalid number; System malfunction
STATUS ALERTS Battery charging, in use, depleted; Delivering;
Priming; Standby mode; Stop/Program
INFUSION MODES g/kg/min, g/kg/hr, mg/kg/min, mg/kg/hr, g/min, g/hr,
mg/min, mg/hr, mu/min, mu/hr, u/min, u/hr, ml/min,
ml/hr, dose volume, delivery time
DIMENSIONS 24 x 10 x 15 cm (9.5 x 4.0 x 5.9 in)
WEIGHT 2.2 kg (4.9 lbs)

Order # Product
PC1 72-0088 MFRP10 Infusion Syringe Pump, 110 VAC
PC1 72-0089 MFRP10 Infusion Syringe Pump, 220 VAC

32 Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com
SYRINGE PUMPS
NEW Model 55 Pump

SYRINGE PUMPS
Model 55 Pump
KEY FEATURES Model 55 Pump Specifications (continued)
Accurate and smooth flow ALARM FUNCTION Alarm indication sent to infusion supervision
management system
Syringe detection
INFORMATION CAN BE Injection complete, near completion, occlusion, low
Advanced occlusion detection battery, disengagement, 3 independent alarms
Battery back-up to AC power BATTERY Rechargeable lithium battery, 7.4V, 1600mAh
Wireless controller option ELECTROMAGNETIC Accord with the stipulation of IEC60601-1-2
WAVE (HERTZIAN WAVE) (1993 edition)
PROTECTION
The Model 55 Syringe Pump is an easy to use syringe pump that can PROPER ENVIRONMENT Environment temperature 5~40, pressure
control the injection rate and total volume precisely and continuously CONDITION 70~106kPa, relative humidity 30%~90%
over long periods of time. This pump has an optional wireless STORAGE CONDITION Environment temperature – 15~50˜,
controller that allows you to control infusion and monitor status pressure 70~106 kPa, relative humidity 30%~90%
remotely.
ELECTRICAL SAFETY accord with the stipulation of GB9706.1-1995
MAXIMUM SIZE 288 x 130 x 122 mm
Model 55 Pump Specifications OF OUTER SHELL

INJECTION ACCURACY ±3% MAXIMUM WEIGHT < 2.5 kg

APPLICABLE SYRINGES 5 ml, 10 ml, 20 ml, 30 ml and 50 ml POWER 50/60Hz AC85- 265 V, 50/60 Hz

FLOW RATE: FUSES 220 V 0.2A ×2, 12 V 2.5A ×2

5 ml Syringe 0.1~100 ml/hr MAXIMUM POWER 25VA, running more than two hours
CONSUMPTION after being charged
10 ml Syringe 0.1~100 ml/hr
DIMENSIONS, H x W x D 24 x 10 x 15 cm (9.5 x 4.0 x 5.9 in)
20 ml Syringe 0.1~ 400 ml/hr
WEIGHT 2.2 kg (4.9 lbs)
30 ml Syringe 0.1~600 ml/hr
50 ml Syringe 0.1~1500 ml/hr
INJECTION INCREMENT 0.1 ml/hr Order # Product
FAST INJECTION Exhaust impingement quantity of fast injection PC1 72-9700 Model 55 Pump with Built-in Controller
QUANTITY 10 m/20 ml/50 ml syringe 1.0 m
PC1 72-9702 Model 55 Pump with Wireless Monitoring
KVO SPEED 0.1 ~ 5.0 ml/hr
ADJUSTABLE RANGE

FAST INJECTION SPEED:


10 ml syringe 100 ml/h
20 ml syringe 200 ml/h
50 ml syringe 500 ml/h

Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com 33
SYRINGE PUMPS
Customized Solutions -
OEM and Special Syringe Pumps
SYRINGE PUMPS

H arvard Apparatus has the broadest selection and experience in fluidics components,
systems and specials. Whether you are doing a one-time experiment that requires a
high performance fluidic device or you are a professional engineer that requires a fluidics
module to integrate into your system we have the solution. These solutions can be used to
meet your application needs and requirements. Harvard Apparatus offers a wide variety of
stand alone pumps and pump modules. If you do not see what you feel is the best solution
for your application, give our expert technical support staff a call as we have the ability to
modify existing pumps or develop new ones for special orders and OEM purchases.
OEM and Special Syringe Pumps

A few of the application areas we have developed OEM solutions for include:
• Drug deposition onto cardiac stents
• Liquid chromatography
• Lab on a chip systems for bio-analysis

OEM Syringe Pump Modules


Order # Flow Rate Average Control Communications
Linear Force
MICROLITER SYRINGE PC1 70-2220 0.001 µl/hr to 6 lbs PC or other RS-232
PUMP MODULE or PC1 70-2225 1.33 ml/min external controller serial input
MILLILITER SYRINGE PC1 70-2219 0.001 ml/hr to 25 lbs PC or other RS-232
PUMP MODULE or PC1 70-2226 44.28 ml/min external controller serial input
HIGH PRESSURE PC1 70-2202 0.0001 µl/hr to 200 lbs PC or other RS-232
SYRINGE PUMP MODULE 220.82 ml/min external controller serial input
PHD ULTRA™ PC1 70-3506 3.06 pl/min to 75 lbs PC or other RS-232 and USB
SYRINGE PUMP MODULE 215.8 ml/min external controller serial input
PHD ULTRA™ PUSH/PULL PC1 70-3508 3.06 pl/min to 75 lbs PC or other RS-232 and USB
SYRINGE PUMP MODULE 215.8 ml/min external controller serial input
PHD ULTRA™ 4400 PC1 70-3510 3.06 pl/min to 200 lbs PC or other RS-232 and USB
SYRINGE PUMP MODULE 215.8 ml/min external controller serial input

Drug Deposition onto Cardiac Stents

34 Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com
SYRINGE PUMPS
Customized Solutions -
OEM and Special Syringe Pumps (continued)

SYRINGE PUMPS
Ternary Gradient System for Liquid Chromatography

OEM and Special Syringe Pumps


Microfluidics- Lab on a Chip!

Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com 35
SYRINGE PUMPS
Customized Solutions -
OEM and Special Syringe Pumps (continued)
SYRINGE PUMPS

OEM Modules: OEM Modules:


Microliter Syringe Pump Module Milliliter Syringe Pump Module
OEM and Special Syringe Pumps

KEY FEATURES KEY FEATURES


Accuracy of ±0.5% Accuracy of ±0.5%
Footprint of 4.5 x 9.25 x 3.25 inches Footprint of 5.3 x 9.5 x 4.25 inches
0.001 µl to 1.33 ml/min 0.001 µl/hr to 44.28 ml/min
WEEE, EU RoHS WEEE, EU RoHS

Microliter Syringe Pump Module Specifications Milliliter Syringe Pump Module Specifications
TYPE Microprocessor single syringe, infusion/withdrawal TYPE Microprocessor single syringe, infusion/withdrawal
ACCURACY ±0.5% ACCURACY ±0.5%
REPRODUCIBILITY ±0.1% REPRODUCIBILITY ±0.1%
SYRINGE TYPE Glass or plastic SYRINGE TYPE Glass or plastic
SYRINGE SIZE: SYRINGE SIZE:
Size Minimum 0.5 µl Size Minimum 0.5 µl
Size Maximum 1 ml Size Maximum 50/60 ml
FLOW RATE: FLOW RATE:
Minimum 0.001 µl/hr Minimum 0.001 ml/hr
Maximum 1.33 ml/min Maximum 44.283 ml/min
AVERAGE LINEAR FORCE 2.73 kg (6 lbs) AVERAGE LINEAR FORCE 11.36 kg (25 lbs)
CONNECTORS: CONNECTORS:
RS-232 4 pin RJ-11 telephone jack; dual RS-232 ports RS-232 4-pin RJ11 telephone jack; dual RS-232 ports
DC Power 4-pin Header (Friction lock) DC Power 2-pin Header (friction lock)
POWER +12VDC, 5%, 1A (12W) (User supplied) POWER +15 to +40VDC (12W min) (user supplied)
DIMENSIONS: DIMESIONS:
Overall, H x W x D 11.4 x 23.5 x 8.3 cm (4.5 x 9.25 x 3.25 x 4.5 in) Overall, H x W x D 13.5 x 24.1 x 10.8 cm (5.3 x 9.5 x 4.25 in)
Mounting 22.2 x 7.0 cm (8.75 x 2.75 in) - Mounting 22.9 x 9.5cm (9.0 x 3.75 in) -
Mounting holes for (4) #8 screws Mounting holes for (4) #8 Screws
WEIGHT 0.84 kg (1.85 lbs) WEIGHT 1.27 kg (2.8 lbs)

Order # Product Order # Product


PC1 72-2220 Microliter Syringe Pump Module without Power Supply PC1 72-2219 Milliliter Syringe Pump Module without Power Supply
PC1 72-2225 Microliter Syringe Pump Module with Power Supply PC1 72-2225 Milliliter Syringe Pump Module with Power Supply

36 Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com
SYRINGE PUMPS
Customized Solutions -
OEM and Special Syringe Pumps (continued)

OEM Modules: OEM Modules:

SYRINGE PUMPS
High Force Syringe Pump Module PHD ULTRA™ Syringe Pump Module

OEM and Special Syringe Pumps


KEY FEATURES KEY FEATURES
Accuracy of ±0.5% Accuracy of ±0.25%
Footprint of 6.6 x 5.5 x 11.8 in 11.75 x 5.5 x 6.5 in
0.001 µl/hr to 220.82 ml/min 3.06 pl/min to 215.8 ml/min
WEEE, Eu RoHS, ETL (UL, CSA) CE, ETL (UL, CSA), WEEE, EU RoHS & CB Scheme

High Pressure Syringe Pump Module Specifications PHD ULTRA™ Syringe Pump Module Specifications
TYPE Microprocessor single syringe, infusion/withdrawal TYPE Microprocessor dual syringe, infusion/withdrawal
ACCURACY ±0.5% ACCURACY ±0.25%
REPRODUCIBILITY ±0.1% REPRODUCIBILITY ±0.05%
SYRINGE TYPE Plastic, glass or stainless steel SYRINGE TYPE Plastic, glass or stainless steel
SYRINGE SIZE: SYRINGE SIZE:
Size Minimum 0.5 µl Size Minimum 0.5 µl
Size Maximum 140 ml Size Maximum 140 ml
FLOW RATE: FLOW RATE:
Minimum 0.001 µl/hr Minimum 3.06 pl/min
Maximum 220.82 ml/min Maximum 215.8 ml/min
AVERAGE LINEAR FORCE 90.91 kg (200 lbs) AVERAGE LINEAR FORCE 34 kg (75 lbs) @ 100% Force Selection
30 VDC Input
CONNECTORS:
CONNECTORS:
DC Power 4-pin Header (Friction lock–Molex or AMP)
RS-232 9 pin D-Sub Connector
RS-232 4-pin RJ-11 Telephone Jack; dual RS-232 ports
RS-485 IEEE-1394, 6 pos
User I/O 9-pin D-Sub Female
USB Type B
DIMENSIONS:
I/O & TTL 15 pin D-Sub Connector
Overall, H x W x D 16.8 x 14.0 x 30.2 cm (6.625 x 5.50 x 11.875 in)
DIMENSIONS
Mounting 28.9 x 12.7 cm (11.375 x 5.00 in),
mounting holes for (4) #8 screws Overall, H x W x D 29.8 x 14.0 x 16.5 cm (11.75 x 5.5 x 6.5 in)
Control Board Mounting 11.43 x 17.78 cm (4.50 x 7.00 in)- WEIGHT 5.1 kg (11.2 lbs)
Mounting holes for (4) #8 screws REGULATORY CERTIFICATIONS CE, ETL (UL, CSA), WEEE, EU RoHS & CB Scheme
WEIGHT 3.86 kg (8.5 lbs)
** Note: operating temperature may be extended with forced air cooling
Order # Product
PC1 70-3506 PHD ULTRA™ Syringe Pump Module with Power Supply
Order # Product
PC1 70-2202 High Pressure Syringe Pump Module without Power Supply

Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com 37
SYRINGE PUMPS
Customized Solutions -
OEM and Special Syringe Pumps (continued)
SYRINGE PUMPS

OEM Modules: PHD ULTRA™ OEM Modules: PHD ULTRA™


Push/Pull Syringe Pump Module 4400 Syringe Pump Module
OEM and Special Syringe Pumps

KEY FEATURES KEY FEATURES


Accuracy of ±0.25% Accuracy of ±0.35%
Footprint of 6.6 x 5.5 x 11.8 in Footprint 11.75 x 5.5 x 6.5 in
0.001 µl/hr to 220.82 ml/min 3.06 pl/min to 215.8 ml/min
WEEE, RoHS, ETL (UL, CSA) CE, ETL (UL, CSA), WEEE, EU RoHS & CB Scheme

PHD ULTRA™ Push/Pull Syringe Pump Module Specifications PHD ULTRA™ 4400 Syringe Pump Module Specifications
TYPE Microprocessor four syringe, push/pull TYPE Microprocessor single syringe, infusion/withdrawal
infusion/withdrawal
ACCURACY ±0.35%
ACCURACY ±0.25%
REPRODUCIBILITY ±0.05%
REPRODUCIBILITY ±0.05%
SYRINGE TYPE Plastic, glass or stainless steel
SYRINGE TYPE Plastic, glass or stainless steel
SYRINGE SIZE:
SYRINGE SIZE:
Size Minimum 0.5 µl
Size Minimum 0.5 µl
Size Maximum 140 ml
Size Maximum 140 ml
FLOW RATE:
FLOW RATE:
Minimum 3.06 pl/min
Minimum 3.06 pl/min
Maximum 215.8 ml/min
Maximum 215.8 ml/min
AVERAGE LINEAR FORCE 91 kg (200 lbs) @ 100% Force Selection
AVERAGE LINEAR FORCE 34 kg (75 lbs) @ 100% Force Selection
CONNECTORS:
30 VDC Input
RS-232 9 pin D-Sub Connector
CONNECTORS:
RS-485 IEEE-1394, 6 pos
RS-232 9 pin D-Sub Connector
USB Type B
RS-485 IEEE-1394, 6 pos
I/O & TTL 15 pin D-Sub Connector
USB Type B
DIMENSIONS
I/O & TTL 15 pin D-Sub Connector
Overall, H x W x D 29.8 x 14.0 x 16.5 cm (11.75 x 5.5 x 6.5 in)
DIMENSIONS
WEIGHT 5.3 kg (11.2 lbs)
Overall, H x W x D 29.8 x 14.0 x 16.5 cm (11.75 x 5.5 x 6.5 in)
REGULATORY CERTIFICATIONS CE, ETL (UL, CSA), WEEE, EU RoHS & CB Scheme
WEIGHT 5.1 kg (11.2 lbs)
REGULATORY CERTIFICATIONS CE, ETL (UL, CSA), WEEE, EU RoHS & CB Scheme
Order # Product

Order # Product PC1 70-3510 PHD ULTRA™ 4400 Syringe Pump Module
with Power Supply
PC1 70-3508 PHD ULTRA™ Push/Pull Syringe Pump Module
with Power Supply

38 Harvard Apparatus phone 508.893.8999 toll free U.S. 800.272.2775 fax 508.429.5732 www.harvardapparatus.com

You might also like