Pathology Wound Healing MCQ
Pathology Wound Healing MCQ
Pathology Wound Healing MCQ
A diabetic patient has an ulcer on their great toe, which statement is false regarding
it’s healing
a) It will heal by secondary intention
b) Substantial scar formation is likely
c) The amount of acute inflammation is small, slowing the healing
d) Wound contraction requires actin containing fibroblasts
e) Large amounts of granulation tissue grow in from the periphery of the wound
Regarding collagen
a) Type V, non-fibillar collagen, is seen in basement membranes
b) Non-fibillar collagen is the most ubiquitous protein in the body
c) Collagen is formed in cells as long fibrils
d) Ehlers-Danlos syndrome is due to a genetic increase in collagen breakdown
e) Collagen is formed in a triple helix structure
1)b
2)d
3)
1) Granulation tissue formation
2) Migration of fibroblasts to site of injury (PDGF, FGF, TNF-B, TNF, IL-1)
3) Proliferation of fibroblasts (PDGF, FGF, TNF)
4) Deposition of extracellular matrix, collagen synthesis
5) Vascular regression
6) Degradation of collagen / ECM by metalloproteinases
4) c
5) e