Lesson Plan in Science 10

I. Objectives
A. Learning Competency: Explain how mutations may cause changes in the structure and
function of a protein
B. Unpacked Competency
At the end of the lesson, the students should be able to:
a. define mutation; and
b. illustrate and differentiate the kinds of chromosomal mutation

II. Content
Main Topic: Heredity: Inheritance and Variation
Sub Topic: Mutation: Changes in the Genetic Code

III. Learning Resources

Teacher’s Guide pp.210-214
Science Learner’s Material pp.281-287
Materials: Visual Aids, Strips of Papers, Video, Projector, Modeling Clay of Varied Color

IV. Teaching-Learning Procedure

Teacher’s Activity Student’s Activity

Preliminary

Good Afternoon Class!

Good Afternoon ma’am
Kindly pick up the scattered pieces of papers
under your chair and arrange your chairs.

(the students will pick up the scattered papers and

arrange their chairs)
Let us all stand and bow down our heads and
feel the presence of our almighty God through
prayer.
AMEN
AMEN
You may now sit down
(the students will sit down)

Who is/are absent today?

None ma’am

A. Reviewing previous lesson or presenting the

new lesson
Yesterday, we have discussed about mutation.
What are informations can you remember?
Yes_______ Mutation is a change in the base sequence of
DNA ma’am

Very Good!
Another information? Mutagens ma’am
Mutagens are in the form of toxic chemicals and
What is\are mutagens? harmful radiations ma’am

Mutation can occur in two different types and Reproductive Cells and Body cells ma’am
what are these?
What are the two types of mutation can occur in
Gene Mutation and Chromosomal Mutation
gamete cells?
ma’am

And what are the four types of chromosomal

Deletion, Translocation, Inversion and
mutation?
Duplication ma’am

B. Establishing a purpose for the lesson

Why do we have to study mutation? Anybody
We need to study mutation because it can cause
from the class who knows the answer?
charges in all aspects of life.

Yes, Very Good!

Mutations are also essential to evolution and
without mutation evolution could not occur.

C. Presenting examples/Instances of the new

lesson
What are some examples of toxic chemicals? Yes Mercury, Ammonia, Chlorine gas, Smoke
______

Over exposure of pregnant women to radiation,

How about Harmful Radiations? Yes ________ X-rays, radio waves, heat, alpha and gamma
ionizing radiation.

Yes! Very Good

D. Discussing new concepts and practicing new

skills #1 It is also known as gametes or germ cells.
First let us define sex cells. What is sex cells?
Very Good! the one of two cells produced by division of the
generative cell in the pollen grain of certain
How about body cells? gymnosperms that in turn divides to produce two
male nuclei or cells

Absolutely!

E. Discussing new concepts and practicing new

skills #2
Now, let us proceed on gene mutation. It is the permanent change in DNA sequence that
makes up a gene
What is gene mutation?

It can also occur at any time during the life of a

cell. A mutation involving a long segment of DNA.
These mutations can involve deletions,
How about chromosomal mutation?
insertions, or inversions of sections of DNA. In
some cases, deleted sections may attach to other
chromosomes, disrupting both the chromosomes
that loses the DNA and the one that gains it. Also
referred to as a chromosomal rearrangement

F. Developing Mastery
(leads to Formative Assessment)

Class, I have here a box that contains strips of

papers. I will group you into three. All you have (the students will pick up strips of paper)
to do is pick one and that will determine who is
your groupmates.

Find your groupmates according to the color of

the strips of paper you are holding. Group 1 will
(the students will proceed to their task area)
stay in front, Group 2 will stay at the back and
Group 3 stay at this side.
Yes ma’am
Are you in respective groups?

In page 284-287 of your module, I want you to

do the activity 6 wherein you are tasked to
illustrate and differentiate the kinds of
chromosomal mutation. Group 1 will do the
Translocation, Group 2 will do the Deletion and
group 3 will do the Inversion.
 I will give you 20 minutes to do the task.
When the time is up present your work in front. Is
that clear?

Yes ma’am
This is the rubric that will determine your
performance
Creativity- 20%
Concept Understanding- 40%
Effort- 20%
Responsiveness- 20%
For a total of 100%

(the students will do their task)

Time starts now

Yes ma’am
Are you done class?

G. Finding practical application of concepts and

skills in daily living

(group 1 will present their work)

Group 1 present your work

Brilliant! Class let us give them five claps

(group 2 will present their work)
Group 2 it’s your time to shine

Very Good! Class let us give them also five

claps (group 3 will present their work)

Group 3 it’s your turn

Nice One! Class let us give them also five

claps.

H. Making Generalizations and Abstractions

about the Lesson

Translocation occurs when a piece of

How are the three chromosomal aberrations chromosome breaks of and attaches to another
different from each other? chromosome.
Inversion involves the breakage of a chromosome
in two places in which the resulting piece of DNA
 is reversed and re-inserted into the chromosome.
Deletion refers to the loss of a segment of DNA or
chromosome.

How are they similar?

Changes that affect the structure of chromosomes
can cause problems with growth, development,
and function of the body’s systems.
These changes can affect many genes along the
chromosome and disrupt the proteins made from
the genes.

Do you think the normal genetic content of the The normal genetic content of the chromosome
chromosome is affected? may be affected. Many diseases are caused by the
effects of inherited genes. In most cases, there is
only a small difference between the DNA
sequence in the defective gene and a normal one.
This difference is enough to cause serious and
often fatal diseases.

I. Evaluating Learning

Answer the following questions. Use ½ sheet

of paper crosswise.
1. _______ are commonly in the form of toxic
chemicals and harmful radiations.
2-3. Mutation can occur in two different types of
cell and these are the ________ and _________.
4. ________ is a permanent change in DNA
sequence that makes up a gene.
5-6. _______ and ________ are two types of
mutations that can occur in gamete cells.
7. It is the changes in the genetic code.
8-10. What are the differences of Translocation,
Deletion and Inversion?
J. Additional activities for application or
remediation

Do an advance reading about the different birth

defects.
References: Science Learner’s Material
pp.288-291

IV. REMARKS

V. REFLECTION
No. of learners with 80% in the evaluation

No. of learner who require additional activities for

remediation who scored below 80%

No. of learners who have cope up with the lesson

Did the remedial lessons work? No. of learners

who have caught up with the lesson

No. of learners who continue to require

remediation

What difficulties did I encounter which my

principal or supervisor can help me solve?

What innovation or localized materials did I use/

discover which I wish to share with other
teachers?
Detailed Lesson Plan in Science 10

Topic:
Main Topic: Heredity: Inheritance and Variation
Sub Topic: Mutation: Changes in the Genetic Code

Date of Execution:

Prepared By:

APPLE GRAPES A.CALIVA

Student Teacher

Checked By:

LERMA V. MOLINA
Cooperating Teacher

Noted:

MARILOU R. VILLA
HT1, RS Department

Further Noted:

CORAZON A. LLAPITAN,Ph.D
Principal II