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Bacteria and Fermentation

The document discusses lactic acid bacteria which are important microbes used in industrial fermentation processes. They are able to metabolize sugars and produce molecules like lactic acid, antimicrobials, flavors, vitamins, and biodegradable plastics. The document also discusses metabolic engineering of lactic acid bacteria and provides an overview of Profacgen which offers industrial scale fermentation services for lactic acid bacteria.

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0% found this document useful (0 votes)
32 views3 pages

Bacteria and Fermentation

The document discusses lactic acid bacteria which are important microbes used in industrial fermentation processes. They are able to metabolize sugars and produce molecules like lactic acid, antimicrobials, flavors, vitamins, and biodegradable plastics. The document also discusses metabolic engineering of lactic acid bacteria and provides an overview of Profacgen which offers industrial scale fermentation services for lactic acid bacteria.

Uploaded by

Anserj339
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PDF, TXT or read online on Scribd
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Bacteria and fermentation

Lactic acid bacteria (LAB) or Lactobacillales are industrially

important microbes used in a large variety of industrial processes

such as food fermentation. Not only do LAB have great potentials

for in situ production of fermented foods, but they also seem

promising in metabolic engineering. Their contribution in

fermentation processes primarily roots from the formation of lactic

acid. Besides, LAB enhance other product characteristics such as

flavor, texture and nutrition.

Metabolic pathway overview to produce some of the most industrial

desired molecules

Figure 1. Metabolic pathway overview to produce some of the most

industrial desired molecules

(Biotechnology Advances, 2014)

The main application of LAB in industrial processes is to serve as

food starters (e.g., for dairy product, pickles, meat and wine). In

addition, they are able to metabolize numerous mono- and

di-saccharides. Furthermore, natural or metabolically engineered

LAB produce many metabolites with confirmed applications:


antimicrobial molecules (e.g., bacteriocins);

food aromas and flavors (e.g., diacetyl and acetaldehyde);

food complements (e.g., vitamins);

food texturing agents (e.g., exopolysaccharides);

sweeteners (e.g., mannitol);

nutraceutical molecules;

bulk chemicals (e.g., lactic acid and ethanol);

biodegradable plastics (i.e., polyhydroxyalkanoates, PHA).

Metabolic engineering is usually applied to broaden the range of

carbon sources or improve its product yield and productivity, largely

for food grade applications. L. lactis is the most extensively studied

species among LAB, along with other species include L. plantarum,

L. brevis, L. panis, and others.

Profacgen provides industry-scale lactic acid bacteria fermentation

with the most advanced technologies and facilities. Our service is

highly customizable from optimization of expression and growth

condition to large-scale production, purification and

characterization. We have the fermentation capacity of up to 10

metric tons, as well as professional one-stop technical support

including:
Strain selection.

Genetic modification.

Growth condition optimization.

Large-scale fermentation.

References:

1. Mazzoli, R., Bosco, F., Mizrahi, I., Bayer, E.A., Pessione, E.

(2014) Towards lactic acid bacteria-based biorefineries.

Biotechnology Advances. 32: 1216-1236.

2. Hugenholtz, J., Smid, E.J. (2002) Nutraceutical production with

food-grade microorganisms. Current Opinion in Biotechnology. 13:

497-507.

INQUIRY

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