GENERIC CLASSIFICATION MECHANISM OF ACTION DOSAGE / INDICATIONS ADVERSE REACTION
Simethicone GIT Regulators, Antiflatulents & Anti- Simethicone, a substance with surface action, causes the gas Relieves accumulation of gas in the GIT, sensation of
Inflammatories bubbles covered with mucus in the stomach and intestine to pressure and fullness in the epigastrium, temporary
Category C: Either studies in collapse. meteorism, gastrocardiac syndrome. Also used in
animals have revealed adverse This brings rapid and noticeable relief of symptoms with preparation for x-ray examination (stomach, intestine,
effects on the foetus (teratogenic commonly sensation of pressure, tension and fullness in the gallbladder, kidney) and before gastroscopy.
or embryocidal or other) and epigastrium, eructations, flatus, pain, intestinal spasm and
there are no controlled studies in removes the gas causing the flatulence. Dimethylpolysiloxane Symptomatic Treatment: Adults: 1-2 tablets, chewed
women or studies in women and is not absorbed in the stomach and intestine, thus has no and/or sucked after every meal and before retiring to
animals are not available. Drugs harmful effect on the organism. bed. School children: 1 tablet, chewed and/or sucked
should be given only if the after every meal and before retiring to bed.
potential benefit justifies the Preparation for Stomach and/or Bowel Investigation: 2
potential risk to the foetus. tablets each, 3-4 times a day on the 2 preceding days
and 2 tablets each when fasting on the morning of the
day of bowel investigation and immediately before the
bowel investigation.