Bionic
Bionic
1. INTRODUCTION 1
2. NEUROPROSTHETICS 3
2.4. ADVANTAGES 7
2.5. CHALLENGES 7
3. BRAIN-COMPUTER INTERFACE 9
3.4.BCI DISADVANTAGES 13
3.5.BCI INNOVATORS 13
4.1.EXOSKELETON 17
4.2.BIONIC EYE 17
4.5.BIONIC EAR 17
4.6.VESTIBULAR IMPLANTS 17
5.BIONIC EYE 20
5.4.ADVANTAGES 24
5.5. DISADVANTAGES 24
6.BIONIC EAR 25
7.CONCLUSION 29
REFERENCES
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LIST OF FIGURES
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Chapter 1
INTRODUCTION
The human body is one of the best creations of nature, for it is an amazing
combination of muscles, sensory organs, neural networks and all. But, over a period of
time and also due to some unforeseen circumstances, some of the natural combinations
cease to work to their potential or get damaged altogether. So it is possible to get back the
glory bestowed on us by Mother Nature? Is it possible to graft a human organ or restore
sensory perceptions to the human body? One major field working towards this is
‘bionics’:an approach where different technologies are coming to make this scenario
possible.
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dental pulp, skin, hippocampus, legs and hands), and functions such as speech. Two
main applications of bionic products are; one being for the restoration of body abilities to
a species-typical norm and the other being the addition of abilities to the body that are not
species-typical. Disabled people are one main group perceived to be in need of
therapeutic interventions that use various bionic products. So far, therapeutic
interventions are about restoration to the species-typical norm. However, therapeutic
bionic products increasingly give the wearer beyond normal body abilities (therapeutic
enhancements). Many so-called non-disabled people want the same enhanced body-
abilities especially through non-invasive bionic products (e.g., non-invasive brain
machine interfaces, exoskeletons).
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Chapter 2
NEUROPROSTHETICS
2.1What is Neuroprosthetics?
Neuroprosthetics (also called Neural Prosthetics) is a discipline related to
neuroscience and biomedical engineering concerned with developing neural
prostheses, artificial implantable devices to replace or improve the function of an
impaired nervous system. Neuroprosthetics are the set of physical devices that
interact with the brain or other neural tissue to augment, restore, or otherwise impact
function. Neuroprosthetics are electrical stimulation technologies that replace or
assist damaged normal functioning neuromuscular organ systems and attempt to restore
normal body processes, create or improve function, and/or reduce pain. These
systems are either implanted or worn externally on the body. Such assistive devices
range from intramuscular stimulation systems designed to limit limb atrophy in
paralysis, to implanted bladder voiding systems and more complex implanted
neuromuscular control. The process of transitioning this technology into a clinically
useful device will require two parallel paths of research.
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placing’. Neuroprosthetic are in their infancy just now, but they offer two things that are
truly wonderful:
Bypassing the body, and letting the mind interface directly with VR, for
the ultimate immersive experience – the virtual body becomes as the
normal functioning body
Augmented body parts will be able to be fitted to the body, and controlled by the
brain as if you were born with them – after a little training, without
conscious thought.
2.2.Blockdiagram
BMI is currently growing with exponential speed, with real successes in linking
human brains to computers, and the control of virtual, and physical prosthetic
limbs via pure thought control as in fig 2.1 . Neuroprosthetics, brain emulation and mind
uploading are together perhaps the most extreme end of the trend towards virtual reality.
All three are BMI, or Brain-Machine Interface. BMI is an old field, stretching back
over six decades, concerned with direct-connecting the human brain to machines,
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in order to improve the function of both. A BMI uses a computer to implement brain
models that translate signals from individual neurons into artificial limb commands.
Discovery of the knowledge needed to uncover the unknown aspects of systems-based
neural encoding and decoding for complex tasks needs highly demanding computational
modeling. The architecture consists of multiple forward-inverse pairs of dynamic
models for movement planning and control. The movement commands are the
combined outputs of selected pairs of models on the basis of real-time feedback signals
The research aims to
identify the types, numbers and combinations of models for complex movement
control and
deploy the cyber infrastructures for both BMI implementation and research. It
uses closed loop experiments where a computer processes brain signals from
rats to control robotic movements.
2.3.1.Sensory Prosthetics
Sensory prosthetics get information into sensory areas like hearing and sight.
2.3.1.1. Visual prosthetics
A Visual prosthetics or bionic eye is a form of neutral prostheses intended to
partially restored lost vision or amplified existing vision. It usually takes the form of an
externally worn camera that is attached to a stimulator on the retina, optical nerve, or in
the visual cortex, in order to produce perceptions in the visual cortex. Research has
produced visual prostheses that give patients fuzzy vision with a pixel resolution of
about 20 x 20, but these are just experimental and not ready for mass use.
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Other visual prostheses place the implant elsewhere, including the sub-retinal space
at the back of the eye, the optic nerve, and the visual cortex. Placed close to its target
cells, the sub-retinal implant requires relatively low energy output to stimulate neuronal
signaling one drawback is that its necessarily small size limits its capacity to generate
power. A solar cell-based prosthetic, stimulated and powered by light, may resolve
this concern and is undergoing clinical trials.
2.3.1.2. Auditory prosthetics
Cochlear implant and auditory brainstem implant. Cochlear implant and auditory
brainstem implant. A cochlear implant (or ’bionic ear’) is a surgically implanted device
that can help provide a sense of sound to a person who is profoundly deaf or severely
hard of hearing. Unlike hearing aids, the cochlear implant does not amplify sound, but
works by directly stimulating any functioning auditory nerves inside the cochlea with
electrical impulses. External components of the cochlear implant include a microphone,
speech processor and transmitter.
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2.4. Advantages
2.5. Challenges
2.5.1.Cranial Nerves
There are twelve cranial nerve pairings (making 24 nerves in total) which split out from
the brain, and move to cover the needs of the cranium and face, rather than make their
way down through the central spinal cord. These nerves are important to consider, as
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most are of critical importance to sensory data, yet do not pass through the central cord,
and so cannot be intercepted at the same juncture.
2.5.2.IBM's blue brain project
The blue brain project's mission is to recreate a human brain through simulation,
replacing neuron by connection. But the project is still in development due to the
complex organization of brain ,and yet need to be decoded for any further advancement.
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Chapter 3
BRAIN-COMPUTER INTERFACE
For generations, humans have fantasized about the ability to communicate and interact
with machines through thought alone or to create devices that can peer into person’s mind
and thoughts. These ideas have captured the imagination of humankind in the form of
ancient myths and modern science fiction stories. However, it is only recently that
advances in cognitive neuroscience and brain imaging technologies have started to
provide us with the ability to interface directly with the human brain .This ability is made
possible through the use of sensors that can monitor some of the physical processes that
occur within the brain that correspond with certain forms of thought.
By reading signals from an array of neurons and using computer chips and programs to
translate the signals into action, BCI can enable a person suffering from paralysis to write
a book or control a motorized wheelchair or prosthetic limb through thought alone.
Current brain-interface devices require deliberate conscious thought; some future
applications, such as prosthetic control, are likely to work effortlessly. One of the biggest
challenges in developing BCI technology has been the development of electrode devices
and/or surgical methods that are minimally invasive. In the traditional BCI model, the
brain accepts an implanted mechanical device and controls the device as a natural part of
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its representation of the body. Much current research is focused on the potential on non-
invasive BCI.
There are two general classes of brain imaging technologies: invasive technologies,in
which sensors are implanted directly on or in the brain, and non-invasive
technologies,which measure brain activity using external sensors. Although invasive
technologies provide high temporal and spatial resolution, they usually cover only very
small regions of the brain. Additionally, these techniques require surgical procedures that
often lead to medical complications as the body adapts, or does not adapt, to the implants.
Furthermore, once implanted, these technologies cannot be moved to measure different
regions of the brain
3.2.How a brain-computer interface work?
As the power of modern computers grows alongside our understanding of the human
brain, we move ever closer to making some pretty spectacular science fiction into reality.
Imagine transmitting signals directly to someone's brain that would allow them to see,
hear or feel specific sensory inputs. Consider the potential to manipulate computers or
machinery with nothing more than a thought. It isn't about convenience -- for severely
disabled people, development of a brain-computer interface (BCI) could be the most
important technological breakthrough in decades. Here, we'll learn all about how BCIs
work, their limitations and where they could be headed in the future.
The reason a BCI works at all is because of the way our brains function. Our brains are
filled with neurons, individual nerve cells connected to one another by dendrites and
axons. Every time we think, move, feel or remember something, our neurons are at work.
That work is carried out by small electric signals that zip from neuron to neuron as fast as
250 mph . The signals are generated by differences in electric potential carried by ions on
the membrane of each neuron.
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Although the paths the signals take are insulated by something called myelin, some of the
electric signal escapes. Scientists can detect those signals, interpret what they mean and
use them to direct a device of some kind. It can also work the other way around. For
example, researchers could figure out what signals are sent to the brain by the optic nerve
when someone sees the color red. They could rig a camera that would send those exact
signals into someone's brain whenever the camera saw red, allowing a blind person to
"see" without eyes.
One of the biggest challenges facing brain-computer interface researchers today is the
basic mechanics of the interface itself. The easiest and least invasive method is a set of
electrodes -- a device known as an electroencephalograph (EEG) -- attached to the
scalp. The electrodes can read brain signals. However, the skull blocks a lot of the
electrical signal, and it distorts what does get through.
To get a higher-resolution signal, scientists can implant electrodes directly into the gray
matter of the brain itself, or on the surface of the brain, beneath the skull. This allows for
much more direct reception of electric signals and allows electrode placement in the
specific area of the brain where the appropriate signals are generated. This approach has
many problems, however. It requires invasive surgery to implant the electrodes, and
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devices left in the brain long-term tend to cause the formation of scar tissue in the gray
matter. This scar tissue ultimately blocks signals.
Regardless of the location of the electrodes, the basic mechanism is the same: The
electrodes measure minute differences in the voltage between neurons. The signal is then
amplified and filtered. In current BCI systems, it is then interpreted by a computer
program, although you might be familiar with older analogue encephalographs, which
displayed the signals via pens that automatically wrote out the patterns on a continuous
sheet of paper.
In the case of a sensory input BCI, the function happens in reverse. A computer converts
a signal, such as one from a video camera, into the voltages necessary to trigger neurons.
The signals are sent to an implant in the proper area of the brain, and if everything works
correctly, the neurons fire and the subject receives a visual image corresponding to what
the camera sees.
Another way to measure brain activity is with a Magnetic Resonance Image (MRI). An
MRI machine is a massive, complicated device. It produces very high-resolution images
of brain activity, but it can't be used as part of a permanent or semipermanent BCI.
Researchers use it to get benchmarks for certain brain functions or to map where in the
brain electrodes should be placed to measure a specific function. For example, if
researchers are attempting to implant electrodes that will allow someone to control a
robotic arm with their thoughts, they might first put the subject into an MRI and ask him
or her to think about moving their actual arm. The MRI will show which area of the brain
is active during arm movement, giving them a clearer target for electrode placement.
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Allow a mute person to have their thoughts displayed and spoken by a computer.
Although we already understand the basic principles behind BCIs, they don't work
perfectly. There are several reasons for this.
The brain is incredibly complex. To say that all thoughts or actions are the result
of simple electric signals in the brain is a gross understatement. There are about
100 billion neurons in a human brain [source: Greenfield]. Each neuron is
constantly sending and receiving signals through a complex web of connections.
There are chemical processes involved as well, which EEGs can't pick up on.
The signal is weak and prone to interference. EEGs measure tiny voltage
potentials. Something as simple as the blinking eyelids of the subject can generate
much stronger signals. Refinements in EEGs and implants will probably
overcome this problem to some extent in the future, but for now, reading brain
signals is like listening to a bad phone connection. There's lots of static.
The equipment is less than portable. It's far better than it used to be -- early
systems were hardwired to massive mainframe computers. But some BCIs still
require a wired connection to the equipment, and those that are wireless require
the subject to carry a computer that can weigh around 10 pounds. Like all
technology, this will surely become lighter and more wireless in the future.
A few companies are pioneers in the field of BCI. Most of them are still in the research
stages, though a few products are offered commercially.
NASA has researched a similar system, although it reads electric signals from the
nerves in the mouth and throat area, rather than directly from the brain. They
succeeded in performing a Web search by mentally "typing" the term "NASA"
into Google [source: New Scientist].
Cyberkinetics Neurotechnology Systems is marketing the BrainGate, a neural
interface system that allows disabled people to control a wheelchair, robotic
prosthesis or computer cursor [source: Cyberkinetics].
Japanese researchers have developed a preliminary BCI that allows the user to
control their avatar in the online world Second Life [source: Ars Technica].
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Chapter 4
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4.1. Exoskeleton
External skeletons are something that crustaceans and insects have naturally. And now
researchers are working on exoskeletons for humans, too. Some devices are meant to
enhance the strength of people who have been weakened from paralysis or old age. But
the military is also looking at exoskeletons to make people stronger.
Bionic eye is an implant that restores the sense of vision in patients suffering from
degenerative retinal conditions. It consists of a retinal implant surgically placed at the
back of the eye and some external devices
It uses brain implants in people with paralysis to allow them to physically interact
with the world.
The loss of a limb can have serious negative effects on a patient—both mentally and
physically. There was a time when the purpose of limb prosthesis was to conceal
disability. But now it helps the subject to restore some of the lost functions too.
A bionic ear (or cochlear implant) is an artificial hearing device, designed to produce
hearing sensations by electrically stimulating nerves inside the inner ear.It consists of an
internal implant device, which is placed under the patient's skin behind the ear during an
implant operation, and an external sound processor which sits behind the ear and is worn
externally, similar to a hearing aid.
limbs and other body parts that are using ever more sensors, processors and motors–they
are becoming more bionic. The goal, of course, is to make prosthetics more sophisticated,
subtle, and ultimately, more closely interfaced with living human beings and therefore
more helpful.
The brain sends signals using both chemicals and electricity. And for decades the main
way to intervene and fix brain problems was through the chemical side — through
drugs.But recently that has begun to change. Some people now receive implants in their
brains that give off electrical currents to simulate their brain cells. Think of it as a
pacemaker for the brain.This technique is called deep-brain stimulation. And it's already
FDA-approved for treating Parkinson's disease and a movement disorder called
dystonia. Medtronic's deep-brain stimulation system, for example, has been implanted in
some 110,000 people. The technique has also been tested in people for psychiatric
illnesses, including obsessive-compulsive disorder and severe depression.
The bionic heart has a small bladed disk spins in the heart at 2,000 revolutions per minute
to pump blood around the body without a pulse, a significant departure from traditional
pulse-based designs, which included balloon-like sacs to pump blood Australian
researchers have developed the world's first bionic heart that pumps blood without a
pulse and it could be ready for human trials within three years. If everything goes
according to plan, the device could provide a real alternative to organ donation for the
hundreds of people who are diagnosed with heart disease every year.
Artificial kidney is actually a development that may eliminate the need for dialysis and
end up with rows of transplants.The device contains thousands of microscopic filters and
a bioreactor that replicates the functions of metabolism and water balance of a real
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kidney.The treatment has proven to be effective - a larger version of the device and its
constituent parts have been successfully tested in animal models and in critically ill
patients. The scientists' goal now and miniaturize the equipment, using the chip
manufacturing technology to create an artificial kidney "the size of a coffee mug," along
with special compartments to insert cultures of living cells of the kidney.
A bionic ankle– foot prosthesis is designed with both passive and active components that
facilitate the generation of net positive work at the prosthetic ankle joint during the stance
phase of walking. This powered prosthesis performs negative and positive work by
employing a series-elastic actuator, comprising a brushless motor and ball-screw
transmission in series with a carbon-composite leaf spring. The motor’s rotary motion is
converted into linear motion through the ball-screw transmission. The in-series leaf
spring improves motor efficiency by storing and returning some of the energy delivered
by the motor
Bionic hand and arm technology is possible primarily because of two facts of
amputation. First, the motor cortex in the brain (the area that controls voluntary muscle
movements)is still sending out control signals even when certain voluntary muscles are
no longer available for control and second when doctors ampute a limb, they don’t
remove all of the nerves that once carried signal to the limbs.
Robotic finger is a wrist-mounted robot equipped with two long digits. A specially
designed algorithm controls the digits, enabling them to move in sync with the wearer's
real fingers.
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Chapter 5
BIONIC EYE
We are able to see because light from an object can move through space and reach our
eyes. Once light reaches our eyes, signals are sent to our brain, and our brain deciphers
the information in order to detect the appearance, location and movement of the objects
we are sighting at. The human eye is the organ which gives us the sense of sight, it allows
us to learn about the surrounding world than any of the other senses.
The eyeball is present in a protective cone-shaped cavity in the skull called the orbit or
socket and measures approximately one inch in diameter. The orbit is covered by layers
of soft, fatty tissue which protect the eye and enable it to turn easily. The important part
of an eye is retina.
The retina lies at the back of the eye and it acts as though the film in a camera act by
receiving and processing everything.
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It comprises a computer chip which is kept in the back of the individual's eye,
linked up using a mini video camera built into glasses that they wear. Images captured by
the camera are beamed to the chip, which translates them into impulses that the brain can
interpret.
Although the images produced by the artificial eye were far from perfect, they
could be clear enough to allow someone who is otherwise blind to recognise faces. The
breakthrough is likely to benefit patients with the most common cause of blindness,
macular degeneration, which affects 500,000 people.This occurs when there is damage to
the macula, which is in the central part of the retina where light is focused and changed
into nerve signals in the middle of the brain. The implant bypasses the diseased cells in
the retina and stimulates the remaining viable cells.
5.3 Working of Bionic Implant
A bionic eye implant that could help restore the sight of millions of blind people could be
available to patients within two years. This device is 2 millimeters across and contains
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some 3,500 micro photodiodes which is placed behind the retina, this collection of
miniature solar cells is designed to convert normal light to electrical signals, which are
then transmitted to the brain by the remaining healthy parts of the retina. A Belgian
device has a coil that covers around the optic nerve, with only four points of electrical
contact. By shifting the phase and varying the strength of the signals, the coil can
stimulate different parts of the optic nerve, rather like the way the electron guns in TVs
are aimed at different parts of the screen. The video signal senters from an external
camera and are transmitted to the implant through a radio antenna and microchip under
the skin just behind the ear. Implants of a microchip, smaller than the head of a pin and
about half the thickness of a sheet of paper were used to remove blindness.
The eye-position monitor controls the image camera's orientation. If the image-
acquisition camera is not mounted on the head, compensation for head movement will be
needed. Finally, if a retinal prosthesis is to receive power and signal input from outside
the eye via an IR beam entering the pupil, the transmitter must be aligned with the
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intraocular chip. The beam has played two roles: one is to sends power, and another is to
send pulse - or amplitude - modulated to transmit image data. Using the control of eye
movement, the main imaging camera for each eye can swivel in any direction. Each of
these cameras--located just outside the users' field of view to avoid blocking whatever
peripheral vision they might have captures the image of the outside world and transmits
the information through an optical fiber to a signal-processing computer worn on the
body.
The Argus II system uses a spectacle-mounted camera which is used to send
information to electrodes in the eye. Patients who tested less-advanced versions of the
retinal implant were able to see light, shapes and movement.
The function of Bionic eye is to take real-time images from a camera and convert into
tiny electrical pulses that help the blind eyes to see.
1: Camera which is implanted on glasses helps to view the image.
2: Signals are sent to hand-held device
3: The information which processed is sent back to glasses and wirelessly transmitted to
receiver under surface of eye.
4: Receiver sends information to electrodes in retinal implant.
5: Electrodes stimulate retina to send information to brain.
Retinal implants can partially restore the vision of people with particular blindness
caused by diseases such as macular degeneration or retinitis pigmentosa. About one and
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half million people worldwide have retinitis pigmentosa, and one in ten people over the
age of fifty five have age-related macular degeneration. Both diseases cause the retinal
cells which process light at the back of the eye to gradually diminish. The new device
invented work by implanting an array of tiny electrodes into the back of the retina. A
camera is used to capture pictures which consist of a processing unit about the size of a
small handheld computer and worn on a belt helps to convert the visual information into
electrical signals.
These are then sent back to the glasses and wirelessly on to a receiver just under the
surface of the front of the eye, which in turn feeds them to the electrodes at the rear.
5.4.Advantages
• It helps to correct the vision.
• There is no necessity to suffer from long and short sights.
• It can be easily implanted .
5.5.Disadvantages
• There are 120 million rods and 6 million cones in the retina of every healthy human
eye. Creating an artificial replacement for these is a risky task.
• Si based photo detectors have been tried in earlier attempts. But Si is toxic to the human
body and reacts unfavorably with fluids in the eye
• it cost about 30,000$
• It will not be helpful for glaucoma patients.
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Chapter 6
BIONIC EAR
6.1Human Ear
Human ear has three parts: External Ear, Middle Ear, Internal Ear as shown in the figure.
If we talk in term of electronics language, the middle ear work like amplifier, the internal
ear works like a spectrum analyser and transducer. The main function of external ear is
just to collect the sound and also to know the direction of sound.
to the small bones names malleus, incus and stapes which are connected in chain. These
small bones vibrate accordingly and transfer their energy to the oval window and round
window. The motions of these windows are opposite to each other in such a way that
when one moves down other moves up. The round window transfers its energy to the
liquid present in the cochlea and there will be vibrations accordingly. There is basilar
membrane in the cochlea which will moves according to the vibrations of the liquid and
this membrane is connected to the hair cells. This cochlea actually acts like spectrum
analyser. Whatever complex signal having different frequencies comes in it, it will
breaks the complex signal into different frequency component and accordingly basilar
membrane displaced and it transfer the different frequency signal to the corresponding
tuned hair cells. There are different bunches of hair cell which are tuned to different
frequencies. These hair cell actually act like transducer which convert mechanical energy
into electrical energy. These hair cell are connected to the auditory nerve which carry the
electrical signal to the brain.
The implant works by using the tonotopic organization of the basilar membrane of the
inner ear. "Tonotopic organization", also referred to as a "frequency-to-place" mapping,
is the way the ear sorts out different frequencies so that our brain can process that
information. In a normal ear, sound vibrations in the air lead to resonant vibrations of
the basilar membrane inside the cochlea. High-frequency sounds (i.e. high pitched
sounds) do not pass very far along the membrane, but low frequency sounds pass farther
in. The movement of hair cells, located all along the basilar membrane, creates an
electrical disturbance that can be picked up by the surrounding nerve cells. The brain is
able to interpret the nerve activity to determine which area of the basilar membrane is
resonating, and therefore what sound frequency is being heard. In individuals with
sensorineural hearing loss, hair cells are often fewer in number and damaged. Hair cell
loss or absence may be caused by a genetic mutation or an illness such as
meningitis. Hair cells may also be destroyed chemically by an ototoxic medication, or
simply damaged over time by excessively loud noises. The cochlear implant bypasses the
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hair cells and stimulates the cochlear nerves directly using electrical impulses. This
allows the brain to interpret the frequency of sound as it would if the hair cells of the
basilar membrane were functioning properly.
The implant is surgically placed under the skin behind the ear. The basic parts of the
device include:
External:
Internal:
a receiver and stimulator secured in bone beneath the skin, which converts the
signals into electric impulses and sends them through an internal cable to
electrodes.
an array of up to 24 electrodes wound through the cochlea, which send the
impulses to the auditory nerves.
7. The appropriate amount of electrical current passes down the appropriate lead wires
to the selected electrodes. The position of the stimulating electrodes within the
cochlea will determine the frequency or pitch of the sounds. The amount of electrical
current will determine the loudness of the sounds.
8. Once the nerve endings in the cochlea are stimulated, the message is sent up to the
brain along the auditory nerve. The brain can then try to interpret the stimulation as a
meaningful sound.
Fig6.2.Bionic ear[5]
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Chapter 7
CONCLUSION
Bionics are a set of technology products that are constantly evolving. Bionics are
proposed as body add-ons or replacement for many body parts (ears, eyes, knees, neural
prostheses, joints, muscles, kidney, liver, cartilage lungs, discs, pancreas, dental pulp,
skin, hippocampus, legs and hands), and functions such as speech.
Disabled people are one main group perceived to be in need of therapeutic interventions
that use various bionic products. So far, therapeutic interventions are about restoration to
the species-typical norm. However, therapeutic bionic products increasingly give the
wearer beyond normal body abilities (therapeutic enhancements). Many so-called non-
disabled people want the same enhanced body-abilities especially through non-invasive
bionic products (e.g., non-invasive brain machine interfaces, exoskeletons).
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