Cold Chain & Immunisation Schedule

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COLD CHAIN &

IMMUNISATION
SCHEDULE
Manufacturer
Cold Chain
Distributor
The ‘cold chain’ is the system of
transporting and storing vaccines at
recommended temperature from the Vaccine
Depots
point of manufacture to the point of use.

Provider
office

Client
Why is the cold chain important ?
1. Vaccines are: 2. Assurance in potent
product and vaccine
 Biological products
programmes
 lose potency with time  Professional responsibility
 Confident the vaccines you give
 Process irreversible and will be effective
accelerated if proper storage  Public Health responsibility
conditions are not adhered to.  Public confidence in
immunisation programmes

3. Ensuring maximum benefit 4.Compliance with


from immunisations SPC/Manufacturer
Responsibility not to waste Any vaccine that has not been
scarce NHS resources stored at a temperature of 2-8ºC as
per its licensing conditions is no
Reduce wastage from errors longer a licensed product
Cold chain storage
equipment
Walk in Deep Ice lined
cold rooms freezers refrigerators
1.Walk in cold rooms(WIC)
At regional level
Storage up to 3 months

2.Deep freezers

At district & PHC levels


Temp :- -15oc to -25oc
At PHC, used only for the
preparation of ice packs
3.Ice lined refrigerators(ILR)

Both at district and PHC


levels
Temp :- +2oc to +8oc
ILR’s are top opening,
can hold cold air inside
better than front opening
refrigerators
Vaccine Stability
MOST
SENSITIVE
Sensitivity to HEAT Sensitivity to COLD

BCG HepB and combination


Varicella DTand/or aP/IPV/HIB
MMR Influenza
MenC MenC
Hepatitis B *MMR
DT and/or aP/IPV/HIB *Varicella
*BCG
Temperature must be LEAST
recorded twice in a day with SENSITIVE (*Freeze dried)
dial thermometer
Light Sensitive

Sensitive to strong light, sunlight, ultraviolet,


fluorescents (neon)
Vaccines should
BCG always be stored
MMR in their original
Varicella packaging until
Meningococcal C Conjugate point of use to
Most DTaP containing vaccines protect them from
light

Immunisation Department, Centre for Infections


Vaccine Storage
DON’T’s DO’s
X No food or medical
Use a dedicated vaccine fridge
specimens

Safeguard electricity supply


X Do not place fridge in
direct sunlight or near heat
source No more than 50% full

Place vaccines in clearly


X Do not store vaccines for labelled plastic mesh baskets
more than 1 month at PHC.
 Group vaccines by type
X Do not store vaccines in (Paediatric, Adult, Adolescent)
fridge doors or in solid
plastic trays/containers Defrost/calibrate fridge regularly
within the fridge
Ensure back up facilities are
X Keep vaccines away from Picture taken from www.medisave.co.uk available in the event of fridge
fridge walls and cold air failing
vents
Transporting Equipment

Cold Vaccine Day


boxes carriers carriers
Used for transport of vaccines
1.Cold boxes Fully frozen ice packs placed
at the bottom and sides
DPT, TT, DT should not be kept
in direct contact

2.Vaccine
carriers

Used to carry small quantity of


vaccines(16 to 20 vials)
For out of reach sessions
4 icepacks are used
3.Day carriers

Used to carry very small quantities


of vaccines(6 to 8 vials)
For a near by session
2 icepacks are used
For only 2 hours period
Use of diluents
Specifically designed to reconstitute
the vaccines with respect to volume,
pH and other chemical properties
Store at +2oc to +8oc in ILR
Only use vaccines suppled and
packaged by manufacturer
Vaccine Vial Monitor(VVM)
VVM is a label containing heat sensitive
material that is placed on a vaccine vial
to register heat exposure over time

Vaccine vial
monitor
• Inner square Combined effects of time and
lighter than temperature cause the inner square
Stage 1 outer circle to darken gradually and irreversibly
VVM does not directly measure the
• Inner square vaccine potency but gives info about
still lighter than the main factor that affects potency
Stage 2 outer circle

• Color of inner
square matches
Stage 3 the outer circle

• Color of inner
square darker
Stage 4 than outer circle
Immunization schedule

Immunization is the
process whereby a
person is made
immune to an
infectious disease,
typically by the
administration of a
vaccine.

Controlling and eliminating life-threatening infectious diseases


Estimated to avert between 2 and 3 million deaths each year.
 One of the most cost-effective health investments
Accessible to even the most hard-to-reach and vulnerable
populations.
Active immunization/vaccination
has been named one of the

"Ten Great Public Health


Achievements in the 20th Century"

Accelerate control Strengthen routine


of vaccine- immunization to
preventable meet vaccination
diseases coverage targets
Objectives of
WHO in
immunization
Spur research and
Introduce new development for
and improved the next generation
vaccines of vaccines and
technologies
Immunization
Schedule

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