Biomedical Research 2017; 28 (12): 5623-5627 ISSN 0970-938X

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Comparison of functional training and strength training in improving knee

extension lag after first four weeks of total knee replacement.
Maryam Shabbir1, Bilal Umar2, Sarah Ehsan3*, Sunaina Munir4, Umoal Bunin5, Khurram Sarfraz6
1Riphah College of Rehabilitation Sciences, Riphah International University, Lahore, Pakistan
2Assistant Professor, Department of Physical Therapy, Imperial College of Business Studies, Lahore, Pakistan
3Department of Physical Therapy, Superior University, Lahore, Pakistan
4Department of Physical Therapy, University of Management and Technology, Lahore, Pakistan
5Department of Physical Therapy, Lahore General Hospital, Lahore, Pakistan
6Ali Hospital, Sahlimar Link Road, Lahore, Pakistan

Abstract
The weakness of quadriceps and reduced activation has been identified as a major cause of activity
limitations post Total knee replacement (TKR). There is a need to evaluate various available techniques
in their effectiveness in improving quadriceps strength and minimizing functional limitations after total
knee replacement. Objective of this study was to determine the effectiveness of strength training as
compared to functional training in improving knee extension lag after first four weeks of Total Knee
Replacement. This Randomized control trial was conducted at Ghurki trust teaching hospital, from
June to December 2015.Patients with total knee replacement were selected consecutively and then
randomly assigned to control group (n=33) and treatment group (n=31). Primary and secondary
outcome measures were goniometry and Visual Analogue Scale (VAS) respectively. There was no
significant difference found in knee extension Lag between the two groups (p-value>0.05). The mean
Value for pain on visual analogue scale was 1.78 (SD=3.03) for control group and 1.33 (SD=3.32) for
treatment group. The difference in mean scores for pain was significantly different for both groups (p-
value<0.05). Both strength training and functional training were found equally effective in improving
quadriceps lag, however, functional training exercises resulted in significant reduction in post-operative
knee pain compare to resistance training. It is recommended to make functional exercises an essential
part of physical rehabilitation post total knee replacement.

Keywords: Arthroplasty, Exercise therapy, Knee joint, pain, Outcome assessment, Resistance training, Visual analogue
scale.
Accepted on May 08, 2017

Introduction delayed activation of quadriceps have been identified as the

major cause of activity limitations post TKR [3,4]. The post-
Overview operative Quadriceps strength has been found to be reduced to
as much as 60% as compared the pre operated strength.
An estimated number of almost over 650,000 total knee Therefore Quadriceps activation is an important consideration
replacement surgeries were done in United States in the year for rehabilitation following a total knee arthoplasty [4].
2010 and by 2030 this number is expected to increase to 3.5 Previous studies have shown the impact of different post-
million [1]. Total knee arthroplasty is performed in order to operative rehabilitation strategies as resistance exercises,
ensure long term pain relief and improve patient satisfaction. weight bearing functional exercises, low and high impact
However, many patients post-TKR have reported persistent sports activities, proprioceptive and balance training. [5-9].
impairments and functional limitations as compared to their However, there is a need to develop evidence based practice
age-matched controls [2]. Despite of the fact that arthritis guidelines. Balance training along with traditional functional
related pain goes away after a knee replacement, the strength training has shown positive effects on the functional recovery
deficits in hip and knee musculature pose problems for the after total knee replacement [6]. There is an increasing trend of
patients leading to functional limitations [3]. The weakness and pre-operative and post-operative outpatient Rehabilitation for

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total knee replacement. [10]. The persistent quadriceps Osteoarthritis of Knee (2) having first TKR surgery, (3) having
weakness and the resulting functional limitations after TKR are post-operative goal to ambulate with or without walking aids
attributed to ineffective post-operative rehabilitation (4) willing to undertake physical therapy interventions and
approaches. A universally accepted protocol for post-operative follow up. Patients for whom total knee arthroplasty was
rehabilitation for total knee replacement is lacking. A recent indicated due traumatic knee injury, rheumatoid arthritis or
study on the post-operative care after TKR has revealed that bone tumors were excluded. Of the 4 surgeons involved in the
26% patients get the out-patient based physical rehabilitation study, 2 were high volume knee replacement surgeons (Defined
after their discharge which can have profound effects on the as more than 80 Total Knee Replacement Surgeries) and 2
long term well-being and quality of life of the patients [11]. surgeons were low volume surgeons. Patients from high and
low volume surgeons were evenly divided in 2 groups.
Strength training with high resistance has been shown to
improve quadriceps strength and activation [4]. Progressive
strength training has been proposed to be started as early as 1
Sample size
to 2 days post op in order to minimize strength deficits in Sample of 64 patients was taken consecutively.
quadriceps [12]. Small to moderate improvements in range of
motion and functional status have been observed with Blinding
functional exercise after 3-4 months of total knee replacement.
Home based unsupervised exercises have also been speculated Treatment protocols were managed to hide from patients and
to reduce pain and disability. But the efficacy of home base assessors. Clinicians, however, had the idea of treatment
exercises and functional exercises in providing long term approach to particular groups. This double blinding was
improvements in range of motion and functional status is maintained throughout course of trial. Outcome assessment
unclear [13]. Therefore there is a need to evaluate the was blinded and carried out by Physical Therapists who were
effectiveness of various techniques in improving quadriceps not involved in intervention tasks. This physical therapist was
strength and minimizing functional limitations after total knee trained in using outcome measures especially the primary one
replacement. Current study hypothesized that functional in this study i.e. Goniometer. Assessor physical therapist and
training program is more effective as compared to conventional patients were blinded from the mode of treatment.
strength training in reducing quadriceps lag after total knee
replacement. Interventions
Control group received muscle strengthening program once per
Objective day for 5 days a week. It consisted of ankle cuff weights.
The objective of this study was to determine the effectiveness Different weight sandbags were used for this purpose. Patients
of strength training as compared to functional training in were demonstrated the procedure and the methods were
improving knee extension lag after first four weeks of Total observed by experienced physical therapist. Treatment group
Knee Replacement. was given functional activities. Functional activities included
squats, lunges and steps (step up, step down).
Material and Methods Functional activities were demonstrated to the treatment group
by trained physical therapists. Patients were observed while
Methods performing those functional activities. They were provided
with illustrated pamphlet of exercises as a home exercise plan.
It was a Randomized Controlled Trial conducted with 4 weeks
follow up. Patients in control group were given strength Primary outcome measure was Goniometry. The range of knee
training and those in treatment group were given functional joint was measured through same procedures. While Visual
training. So the primary variables of study were strengthening Analogue Scale (VAS) was used as secondary outcome
exercises given as outpatient basis and strengthening through measure to measure pain level [14].
functional activities given as home plan. The details of these
variables are mentioned in next section under the heading Statistical calculations and analysis
“Intervention”. The subjects were selected through purposive
Analysis was based on “intention to treat” basis. Means,
sampling technique and then randomly allocated to either
medians, standard deviations were generated for major
control or experimental group by using lottery method. The
variables of study. The data was analyzed through SPSS 20.0.
allocation process was concealed and was performed by a
Paired sample t-test was used and the change in knee extension
research assistant who was not involved in any further step of
lag and pain level were measured at different levels of follow
research (Figure 1).
up, because improvement in quadriceps lag was primary
outcome and improvement in pain was major secondary
Patients outcome of trial.
Participants were taken from the list of patients that were
waiting for Total Knee Replacement. Patients who met
following eligibility criteria were selected: (1) diagnosed with

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Knee extension lag after total knee replacement

Ethical approval and data storage **TKR in which surgeon applied a separate piece on backside of patella to

smoothen its movements on implant.

Ethical approval was obtained and stored according to data
protection and storage act [6].
Results
Sixty four subjects participated in the study. Subjects were
similar in both groups in their demographic characteristics
(Table 1) and were also same at base line measurements of all
out come measures (Table 2). Total 64 patients (30 patients in
treatment group and 31 patients in control group) followed up
for 4 weeks post operatively. The average values of Quadriceps
Lag on Baseline for control group and treatment group were
4.44 (SD=4.93) and 7.33 (SD=9.01) respectively. At 2nd
measurement after two weeks for the mean values for control
group and treatment group were 4.89 (SD=4.86) and 4.11
(SD=4.49) respectively. Final value measurement taken at end
of 4th week was Mean=1.67 (SD=3.04) for control group and
for treatment group it was Mean=1.33 (SD=3.32).The p-value
at final measurement was 0.77 (Table 3).

Table 2. Baseline measurements of treatment and control groups on

WOMAC pain, WOMAC function, Taking pain relieving drugs,
Impairment in lower limb, Co-Morbidities, Quadriceps strength, SF
bodily pain, Social health, mental health and Role function.

Treatment Group Control Group

n=30 Mean(SD) n=31 Mean(SD)

WOMAC pain 48 (15) 49 (20)

WOMAC function 48 (17) 50 (19)

Taking drugs to relieve pain 39 (75) 43 (79)

Impairment in other lower limb joints 37 (71) 34 (62)

Co-Morbidities

Cardiac Disease 5 (10) 8 (15)

Figure 1. Flow chart showing enrollment, intervention allocation,
and follow-up of the patients. Chronic Pulmonary Disease 2 (4) 1 (2)

Table 1. Baseline characteristics of treatment and control groups- Hypertension 28 (54) 31 (57)
demographics and surgical intervention.
Diabetes 9 (17) 13 (24)

Demographics Treatment Group Control Group p-value Kidney Disease 3 (6) 1 (2)
n=31 Mean(SD) n=33 Mean(SD)
Neurologic Disease 0 (0) 1 (2)
Age, Years 60 (10) 71 (12) 0.69
Strength of Quadriceps 23 (12) 24 (11)
Body Mass Index 32 (6) 31 (5) 0.40
SF-Bodily Pain 39 (17) 38 (117)
Female, n (%) 39 (60) 33 (50) 0.29
SF-Mental Health 73 (16) 74 (16)
Diagnosis of Osteoarthritis, n 63 (96) 64 (97) 0.51
SF-Social Function 68 (28) 67 (27)
(%)
SF-Role Emotional 66 (39) 60 (43)
No Co Morbid Condition, n (%) 28 (70) 22 (55) 0.36

>1 joint with osteoarthritis 33 (51) 38 (58) 0.73

Discussion
High Volume Surgeon* 43 (78) 48 (80) 0.82
The main concern of this study was to establish evidence
Patella Resurfaced** 28 (51) 32 (53) 0.85
regarding the effectiveness of strengthening exercise regime
Independent t test, Chi-square test versus functional training to restore extensor lag in patients
*High Volume Surgeons defined who has done more than 80 Total Knee after Total Knee Replacement. In previous studies, various
Replacement Surgeries in their career. protocols have been used showing variability in results for

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post-operative rehabilitation after TKR. Balance and functional the secondary outcome i.e. pain for the participants in
training have been studied for their effectiveness in improving interventional group. This supports the use of functional
balance after TKR [6] but current study focuses on two activities over strengthening exercises. These results would be
different treatment regimens for correction of extensor lag. helpful in improving quality of life of patients who are unable
Current study has shown that the difference in effectiveness of to get the outpatient physical therapy treatment and prefer a
strength training and functional training in reducing extensor home based plan of exercise instead.
lag was not significant. Significant improvement was found in

Table 3. Comparison of average values of Pain on Visual analogue scale and knee extension Lag in degrees between control and treatment groups.

Control group (n=31) Treatment group (n=31)

Mean (SD) Median Mean (SD) Median

Post Opp. 1st Day of Group A: Pain Level on VAS 7.56 (1.33) 8.00 7.67 (1.00) 8.00

Post Opp. 2nd Week of Group A: Pain Level on VAS 5.89 (1.69) 6.00 4.56 (0.88) 5.00

Post Opp. 4th Week of Group A: Pain Level on VAS 5.00 (0.71) 5.00 2.22 (1.30) 2.00

Post Opp. 1st Day of Group A: Extension Lag in Degrees 5.00 (4.85) 5.00 7.33 (9.01) 5.00

Post Opp. 2nd Week of Group A: Extension Lag in Degrees 4.44 (4.93) 3.00 4.11 (4.49) 3.00

Post Opp. 4th Week of Group A: Extension Lag in Degrees 1.78 (3.03) .00 1.33 (3.32) .00

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