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Anatomy and Physiology

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ANATOMY AND PHYSIOLOGY

Respiration

 Function

 Move air in and out of lungs (ventilation)

 Delivers oxygen (O2)

 Removes carbon dioxide (CO2)

 In addition to respiration

 Regulation of blood pH

 Voice production

 Olfaction

 Innate Immunity

 Divisions of the Respiratory System

 Upper respiratory tract (outside thorax)

 Nose

 Nasal Cavity

 Pharynx

 Nose
- Consist of external nose and nasal cavity

- Nares are the external openings of the nose

- Choanae are the opening into the pharynx

- Nasal cavity extends from the nares to the choanae

- Nasal Septum diving the nasal cavity into right and left parts

Function of the Nose

- The only externally visible part of the respiratory system that functions by:
- Providing an airway for respiration
- Moistening (humidifying) and warming the entering air
- Filtering inspired air and cleaning it of foreign matter
- Housing the olfactory receptors
- Resonating chamber that amplifies the voice

 Pharynx

- Pharynx - (throat)

3 divisions

 Nasopharynx – joins the nasal cavity through the choanae and contains the
opening to the auditory tube and the pharyngeal tonsils

 Oropharynx – joins the oral cavity and contains the palatine and lingual tonsils.

 Laryngopharynx – opens into the larynx and the esophagus

 Divisions of the Respiratory System


 Lower respiratory tract (within thorax)

 Larynx

 Trachea

 Bronchial

 Lungs

 Larynx

 Larynx – “voice box”

- Located in the anterior throat and extends from the base of the tongue to the
trachea.

- It is a passageway for air between the pharynx and the trachea

- Made of 9 cartilage

 2 pairs of folds

 Vestibular - false vocal cords

 vocal cords – true vocal cords

3 unpaired cartilage:
 Thyroid cartilage “adam’s apple”- the largest cartilage unpaired and is attached
superiorly to the hyoid bone.

 Cricoid cartilage –inferior cartilage unpaired forms the base of the larynx on which the
other cartilages rest

 Epiglottis – it differs from the other cartilages in that it consist of elastic cartilage rather
than hyaline cartilage

Six paired cartilage consist of three cartilage:

 Cuneiform cartilage

 Corniculate cartilage

 Arytenoid cartilage

Vocal Cords

 Stretched between the thyroid cartilage and the cricoid cartilage

 Upper – false cords

 Lower – true vocal cords

 Glottis – the opening between the vocal cords

 Laryngitis – inflammation of the mucous epithelium of the vocal


folds

 Trachea
- or windpipe

- Is a membranous tube attached to the larynx

- Tubular organ made of connective tissue and smooth muscle

- The adult trachea is about 1.4-1.6 cm in diameter and about 10-11cm long

- Lined with cells possessing cilia (microscopic hair-like projections)

Bronchi

- divided into left and right bronchi

 Bronchi

- Tubes that branch off trachea and enter into lungs

- Gas exchange with blood occurs in sacs.

 Primary

 Secondary

 Tertiary

 Bronchioles

 Branch off tertiary bronchi

Bronchi

 Alveoli

 Thin sacs of cells


surrounded by
capillaries

 Secrete surfactant

 Fatty substance

 Helps maintains the inflation


of the alveoli between inspirations

Lungs

- Principal organs of respiration

- Cone-shaped organs

- Right lung – three lobes : superior, middle, inferior lobes

- Left lung – two lobes: superior and inferior

- Pleura – membranes surrounding the lungs

- Bronchopulmonary segment

- Separated by deep, prominent fissures on the lung surface

- Left lung : 9 bronchopulmonary segment

- Right lung : 10 bronchopulmonary segment

- The main bronchi, branch many times to form Tracheobronchial tree, each divides into
lobar bronchi as they enter their respective lungs.

 Lobar bronchi : 2 left lung and 3 right lung

 Segmental bronchi – which extend to the bronchopulmonary segments of the lungs

 Bronchioles – also subdivide numerous times to give rise to terminal bronchioles

 Respiratory Bronchioles

- Each subdivides to form alveolar ducts, which are like long branching hallways with
many open doorways.
- the doorways open into alveoli which are small air sacs

- there are about 300 million alveoli in the lungs

 The Mechanisms of Breathing

Inspiration

- Air rich in O2 enters the lungs from the atmosphere

- The diaphragm contracts or flattens

- The intercostal muscles raise


the ribs

Expiration

- Air rich in C02 exits the lungs

- The diaphragm relaxes

- The intercostal muscles lower the ribs

 The Transport of Oxygen and Carbon Dioxide in the Blood

- Most of the oxygen


binds to hemoglobin

- Oxyhemoglobin
- Bright red in color
- Some oxygen remains
dissolved in plasma
- If CO2 combines with hemoglobin at O2 sites, it forms carboxyhemoglobin
- Carbon dioxide gets into the bloodstream
- Reacts with water in plasma and forms carbonic acid
- Carbonic acid ionizes and releases hydrogen and bicarbonate ions
- Bicarbonate ions attach to hemoglobin
- Exhaled as waste product in the lungs

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