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    A.3 Disturbance of Unidirectional Airflow: ISO 14644-4:2001 (E)

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    Masthan GM
    The document discusses minimizing disturbances to unidirectional airflow in cleanrooms. It notes physical obstacles and operating procedures should consider aerodynamic requirements to prevent turbulence near sensitive work. Appropriate measures should be taken to avoid cross-contamination between work stations and flow disturbances.

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    A.3 Disturbance of Unidirectional Airflow: ISO 14644-4:2001 (E)

    Uploaded by

    Masthan GM
    33 views1 page
    The document discusses minimizing disturbances to unidirectional airflow in cleanrooms. It notes physical obstacles and operating procedures should consider aerodynamic requirements to prevent turbulence near sensitive work. Appropriate measures should be taken to avoid cross-contamination between work stations and flow disturbances.

    Original Description:

    Pharmaceutical

    Original Title

    02. Unidirectional Air Flow

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    The document discusses minimizing disturbances to unidirectional airflow in cleanrooms. It notes physical obstacles and operating procedures should consider aerodynamic requirements to prevent turbulence near sensitive work. Appropriate measures should be taken to avoid cross-contamination between work stations and flow disturbances.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    33 views1 page

    A.3 Disturbance of Unidirectional Airflow: ISO 14644-4:2001 (E)

    Uploaded by

    Masthan GM
    The document discusses minimizing disturbances to unidirectional airflow in cleanrooms. It notes physical obstacles and operating procedures should consider aerodynamic requirements to prevent turbulence near sensitive work. Appropriate measures should be taken to avoid cross-contamination between work stations and flow disturbances.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
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    ISO 14644-4:2001(E)

    A.3 Disturbance of unidirectional airflow

    In unidirectional airflow cleanrooms, the design of physical obstacles such as the process equipment, and the
    operating procedures, personnel movements and product handling, should consider basic aerodynamic
    requirements to prevent serious turbulence in the vicinity of the contamination-sensitive activity. Appropriate
    measures should be taken to avoid flow disturbances and cross-contamination between different work stations.

    Figure A.3 shows the influence of physical obstacles (on the left) and appropriate measures for minimizing the
    impact of these (on the right).

    Flow obstacles causing Adjustments to equipment and behaviour


    a flow disturbance to improve airflow

    a) Improvement by arrangement

    b) Improvement by structure

    c) Improvement by personnel behaviour

    d) Improvement by airflow concept


    Key
    1 Heat source
    a Local increase in air velocity.

    Figure A.3 — Influence of personnel and objects on unidirectional airflow

    12 © ISO 2001 – All rights reserved

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