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    Tunicamycin Ab120296 - Abcam

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    Nabilah
    Tunicamycin is an antibiotic that inhibits protein glycosylation. It works by inhibiting the transfer of N-acetylglucosamine-1-phosphate in the first step of glycoprotein synthesis. Tunicamycin is a mixture of related compounds derived from Streptomyces that is over 99% pure and soluble in DMSO. It can be stored at 4°C for up to 12 months and is used in functional studies to inhibit N-linked protein glycosylation.

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    Tunicamycin Ab120296 - Abcam

    Uploaded by

    Nabilah
    46 views2 pages
    Tunicamycin is an antibiotic that inhibits protein glycosylation. It works by inhibiting the transfer of N-acetylglucosamine-1-phosphate in the first step of glycoprotein synthesis. Tunicamycin is a mixture of related compounds derived from Streptomyces that is over 99% pure and soluble in DMSO. It can be stored at 4°C for up to 12 months and is used in functional studies to inhibit N-linked protein glycosylation.

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    Tunicamycin ab120296 - Abcam

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    Tunicamycin ab120296 - Abcam

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    Tunicamycin is an antibiotic that inhibits protein glycosylation. It works by inhibiting the transfer of N-acetylglucosamine-1-phosphate in the first step of glycoprotein synthesis. Tunicamycin is a mixture of related compounds derived from Streptomyces that is over 99% pure and soluble in DMSO. It can be stored at 4°C for up to 12 months and is used in functional studies to inhibit N-linked protein glycosylation.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
    46 views2 pages

    Tunicamycin Ab120296 - Abcam

    Uploaded by

    Nabilah
    Tunicamycin is an antibiotic that inhibits protein glycosylation. It works by inhibiting the transfer of N-acetylglucosamine-1-phosphate in the first step of glycoprotein synthesis. Tunicamycin is a mixture of related compounds derived from Streptomyces that is over 99% pure and soluble in DMSO. It can be stored at 4°C for up to 12 months and is used in functional studies to inhibit N-linked protein glycosylation.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Download as pdf or txt
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    Product Datasheet

    Tunicamycin ab120296

    Overview

    Product name Tunicamycin


    Description Antibiotic. Protein glycosylation inhibitor.
    Biological description Nucleoside antibiotic that inhibits protein glycosylation. Inhibits GlcNAc phosphotransferase (GPT) and inhibits
    the transfer of N-acetylglucosamine-1-phosphate from UDP-N-acetylglucosamine to dolichol phosphate in the first
    step of glycoprotein synthesis. Inhibits N-linked glycosylation and blocks the formation of N-glycosidic protein-
    carbohydrate linkages. Active in vitro against Gram-positive bacteria, yeasts, fungi and viruses.
    Purity > 99%
    General notes This compound is a mixture of the homologs of tunicamycin: A, B, C and D which vary in the carbon chain length
    (n=8 to 11)

    Properties

    Molecular Weight 844.95


    Chemical structure

    Molecular formula C39H64N4O16 (for tunicamycin C, n = 10)

    CAS Number 11089-65-9


    Storage instructions Store at +4°C (desiccating conditions).
    Solubility overview Soluble in DMSO to 50 mM
    Handling Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for
    up to 12 months.
    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up
    stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C.
    Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that
    you allow your product to equilibrate to room temperature for at least 1 hour.
    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for
    more details.

    Source Streptomyces sp.

    Applications

    Our Abpromise guarantee covers the use of ab120296 in the following tested applications.
    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
    Application Abreviews Notes
    Functional Studies Use at an assay dependent concentration.

    http://www.abcam.com/Tunicamycin-ab120296.html 1
    Product Datasheet
    Please note: All products are "FOR RESEARCH USE ONLYAND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE, NOT FOR USE IN HUMANS"

    Our Abpromise to you: Quality guaranteed and expert technical support

    Replacement or refund for products not performing as stated on the datasheet


    Valid for 12 months from date of delivery
    Response to your inquiry within 24 hours

    We provide support in Chinese, English, French, German, Japanese and Spanish


    Extensive multi-media technical resources to help you
    We investigate all quality concerns to ensure our products perform to the highest standards

    If the product does not perform as described on this datasheet, we will offer a refund or replacement. For full details of the Abpromise, please visit
    http://www.abcam.com/abpromise or contact our technical team.

    Terms and conditions

    Guarantee only valid for products bought direct from Abcam or one of our authorized distributors
    Abcam biochemicals are novel compounds and we have not tested their biological activity in house. Please use the literature to identify how to use these products
    effectively. If you require further assistance please contact the scientific support team

    Visit us at: www.abcam.com

    http://www.abcam.com/Tunicamycin-ab120296.html 2

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