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Polyps Surgical

The document discusses colorectal polyps, classifying them as either non-neoplastic or neoplastic. Neoplastic polyps, also known as adenomas, have malignant potential and can develop into colorectal cancer through the adenoma-carcinoma sequence over 10 years. Adenomas make up 70% of all colorectal polyps and are more common in older individuals, with 70% located in the left colon and 70% being solitary and small in size.

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CHANDREN ARUMUGAM
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153 views8 pages

Polyps Surgical

The document discusses colorectal polyps, classifying them as either non-neoplastic or neoplastic. Neoplastic polyps, also known as adenomas, have malignant potential and can develop into colorectal cancer through the adenoma-carcinoma sequence over 10 years. Adenomas make up 70% of all colorectal polyps and are more common in older individuals, with 70% located in the left colon and 70% being solitary and small in size.

Uploaded by

CHANDREN ARUMUGAM
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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Download as PDF, TXT or read online on Scribd
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Colorectal polyps

l Visible protrusion
above the surface of
the surrounding
normal large bowel
mucosa
Classification of colorectal polyps

Histological classification Polyp type Malignant potential

Non-neoplastic Hyperplastic No
Hamartomatous
(juvenile, Peutz-Jeghers)

Lymphoid

Inflammatory
Tubular adenoma
Neoplastic (adenoma) Yes
(0-25% villous tissue)

Tubulovillous adenoma
(25-75% villous tissue)

Villous adenoma
(75-100% villous tissue)
Classification of colorectal polyps

Histological classification Polyp type Malignant potential

Non-neoplastic Hyperplastic No
Hamartomatous
(juvenile, Peutz-Jeghers)

Lymphoid

Inflammatory
Tubular adenoma
Neoplastic (adenoma) Yes
(0-25% villous tissue)

Tubulovillous adenoma
(25-75% villous tissue)

Villous adenoma
(75-100% villous tissue)
Adenomas – facts and figures

l  70% of all colorectal polyps

l  Increase with age (33% of population by 50yr, and in 50% by 70yr)

l  70% located in the left colon

l  70% are solitary (30% synchronous)

l  70% are small (<1cm in size)

l  7% have severe dysplasia, 3-5% have invasive cancer


Adenoma-carcinoma sequence
10 years

Adenoma CRC

Regardless of aetiology, most CRC arise from adenomas

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