Soal MCQ IMO Tropical Infection Tahap 1

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SOAL SELEKSI IMO CABANG TROPICAL INFECTION

FAKULTAS KEDOKTERAN UNIVERSITAS MULAWARMAN


TAHUN 2016

1. Influenza A has ..........


A. 18 distinct H subtypes and 10 distinct N subtypes
B. 19 distinct H subtypes and 11 distinct N subtypes
C. 18 distinct H subtypes and 11 distinct N subtypes
D. 19 distinct H subtypes and 10 distinct N subtypes
E. 16 distinct H subtypes and 10 distinct N subtypes

2. What is the microorganism seen on the microscope below :

A. Treponema pallidum
B. Neisseria gonorrhoeae
C. Chlamydia trachomatis
D. Trichomonas vaginalis
E. Candida albicans

3. Window period occurs when ..........


A. HBsAg (+), Anti HBs (-), Anti HBc (-)
B. HBsAg (-), Anti HBs (-), Anti HBc (+)
C. HBsAg (-), Anti HBs (+), Anti HBc (-)
D. HBsAg (+), Anti HBs (-), Anti HBc (+)
E. HBsAg (+), Anti HBs (-), HbcAg (+)

4. Which is schistosoma species that can cause urogenital schistosomiasis ?


A. Schistosoma mansoni

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B. Schistosoma japonicum
C. Schistosoma mekongi
D. Schistosoma haematobium
E. Schistosoma intercalatum

5. The CDC case definition for measles requires :


1) Myalgia
2) A generalized maculopapular rash of at least 3 day’s duration
3) Fever of at least 39,3ºC
4) Cough, Coryza, or conjunctivitis

6. A girls (11 y.o.) comes to the hospital with high fever (40,5ºC), especially in the
afternoon for 1 week. With headache, diarrhea, anorexia, nausea, and vomiting. Two
weeks before, she ate the food purchased from street vendors. On physical examination,
doctor found dirty tongue and abdominal tenderness. What is the gold standard
examination for diagnosing this case ?
A. Gall culture
B. Widal test
C. ELISA
D. PCR
E. Blood culture

7. A man (40 y.o.) is brought to the hospital with headache, feverishness, chills, myalgia,
malaise, cough, and sore throat. Then, the doctor do a supportive examination and
obtained the following results :

What management is given to the case ?


A. Amantadine 5 mg/kg in 2 divided doses
B. Oseltamivir 75 mg PO bid
C. Rimantadine 100-200 mg/days

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D. Zanamivir 10 mg bid by inhalation
E. Rimantadine 100 mg PO bid

8. These statement are true, EXCEPT ..........


A. Acute Hepatitis C : HBsAg (-), IgM Anti-HAV (-), IgM Anti-HBc (-), AntiHCV (+)
B. Acute Hepatitis B : HBsAg (+), IgM Anti-HAV (-), IgM Anti-HBc (-), Anti HCV (-)
C. Acute Hepatitis A : HBsAg (-), IgM Anti-HAV (+), IgM Anti-HBc (-), Anti HCV (-)
D. Acute Hepatitis A and B : HBsAg (+), IgM Anti-HAV (+), IgM Anti-HBc (+), Anti
HCV (-)
E. Acute Hepatitis A superimposed on chronic hepatitis B : HBsAg (+), IgM Anti-
HAV (+), IgM Anti-HBc (-), Anti HCV (-)

9. Classic sites of mumps virus replication include :


1) Central Nervous System (CNS)
2) Testes
3) Salivary glands
4) Mammary glands

10. Congenital toxoplasmosis in neonates are treated with :


1) Pyrimethamine
2) Sulfadiazine
3) Folinic acid
4) Spiramycin

11. Transient manifestations in infants with congenital rubella syndrome :


A. Hearing impairment/deafness
B. Congenital heart defects
C. Microcephaly
D. Central nervous system sequelae
E. Hepatosplenomegaly

12. The following statements are true about CMV (Cytomegalovirus) disease in the
immunocompromised host, EXCEPT ..........

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A. Person with AIDS has a risk factors for CMV diseases if CD4+ T cells < 100/μL;
CMV seropositivity
B. Organ transplant recipient has a risk factors for CMV diseases if seropositivity of
donor and/or recipient; potent immunosupresive regimen; treatment of rejection
C. Hematopoietic stem cell transplant recipient with CMV disease has principal
syndromes such as pneumonia and gastrointestinal disease
D. The treatment given to neonates with symptomatic CMV disease is cidofovir
E. The treatment given to the person with AIDS who has CMV disease is ganciclovir,
valganciclovir, foscarnet, or cidofovir

13. The following statements are true about HSV (Herpes Simplex Virus), EXCEPT ..........
A. The incubation period of HSV ranges from 1 to 26 days (median, 6-8 days)
B. Genital HSV-2 infection is twice as likely to reactivate than genital HSV-1 infection
C. Genital HSV-2 infection is recurs 8-10 times more frequently than genital HSV-1
infection
D. Gingivomastitis and laryngitis are the most common clinical manifestasions of first-
episode HSV-1 infection
E. Oral-labial HSV-1 infection recurs more frequently than oral-labial HSV-2 infection

14. The statements below are not included in the characteristics of IRIS (Immune
Reconstitution Inflammatory Syndrome) is ..........
A. Is frequently seen in the setting of tuberculosis; particularly when cART is starting
soon after initiation of anti-TB therapy
B. Occurs weeks to months following the initiation of antiretroviral therapy
C. Is most common in patients starting therapy with a CD4+ T cell count <100/μL who
experience a precipitous drop in viral load
D. Paradoxical worsening of an existing clinical condition or abrupt appearance of a
new clinical finding (unsmasking) is seen following the initiation of antiretroviral
therapy
E. Can be fatal

15. A man (25 y.o.) is brought to the hospital with colicky abdominal pain, bloody diarrhea,
and anemia. From anamnesis, it is known that the patient has dermatitis berfore the

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symptom that are felt right now appeared. A few days ago, the patient went to fishing at
one of the lake near his house. What is the treatment given for this case ?
A. Praziquantel 25 mg/kg, 3 doses in 1 day
B. Praziquantel 20 mg/kg, 2 doses in 1 day
C. Triclabendazole 10 mg/kg once
D. Praziquantel 25 mg/kg, 2 doses per day for 2 days
E. Triclabendazole 20 mg/kg once

16. A man (30 y.o.) comes to the hospital with malodorous wounds on the soles of his feet.
The complaint begins with the patient tread on the shard when cleaning gutters. Initially,
he tried to clean his wound by himself. However, also didn’t recover. On physical
examination found foul-smelling pus and on the wound margins found a black bullae.
What is the name of the microorganisms that cause this disease ?
A. Clostridium perfringens
B. Escherichia coli
C. Staphylococcus aureus
D. Clostridium tetani
E. Streptococcus pyogenes

17. What is the treatment given for the case number 16 ?


1) Penicillin G (4 mU IV q4-6 h) + Clindamycin (600-900 mg IV q6-8 h)
2) Penicillin 3-4 mU IV q4-6 h + Clindamycin (600-900 mg IV q6-8 h)
3) Cefoxitin (2 g IV q6h) + Clindamycin (600-900 mg IV q6-8 h)
4) Clindamycin alone or Metronidazole or Vancomycin

18. A girl (7 y.o.) with springy and itching all over the face, body, and arms since three days
ago. Four days ago, she had a fever. On physical examination found vesicles containing
clear fluid (tear drops) based on erythematous skin and spread. Microorganisms that
cause disease in this case is ..........
A. VZV
B. HSV-1
C. HSV-2
D. HPV
E. CMV

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19. A woman (26 y.o.), 7 months pregnant, with fluor albus and itchy since 2 months ago.
On physical examination found hyperemia vulva and vaginal mucosal, maceration,
cervical edema, hyperemia, erosion, and white flour albus thick like milk. What is the
diagnosis for this case ?
A. Trichomonas vulvovaginitis
B. Bacterial vaginosis
C. Chlamydial servisitis
D. Gonorrhea servisitis
E. Candida vulvovaginitis

20. A woman (27 y.o.) with skin disorders for 2 days, often stiff, and left chest pain. On
physical examination found clustered vesicles on the basis of erythematous and her
vesicles multiply. What is the diagnosis for this case ?
A. Varicella
B. Herpes simpleks
C. Herpes zoster
D. Measles
E. Dermatitis herpetiformis

21. A woman (23 y.o.) comes to the hospital with discharge from vagina. On the physical
examination found multiple vesicles containing clear fluid in the vulva and vagina. On
the histopathologic examination found some multinucleated giant cells with intranucleus
inclusion and glass cell. What is the diagnosis for this case ?
A. Cytomegalovirus
B. Human Papilloma Virus (HPV)
C. Candida albicans
D. Herpes Simplex Virus (HSV)
E. Rubella

22. A man (33 y.o.) comes to the hospital with shortness of breath since 2 days ago, red rust
hemaptoe, fever (+), blood pressure = 130/85 mmHg, pulse = 90 bpm, and respiratory
rate = 44 times/minutes. On the X-ray examination of his thorax found diffuse infiltrates.
What is the common cause of this case ?
A. Haemophilus influenzae

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B. Staphylococcus aureus
C. Staphylococcus pneumoniae
D. Pseudomonas aeruginosa
E. Mycobacterium tuberculosis

23. A woman (27 y.o.) comes to the hospital with a history of sexual contact + 3 days ago.
On the physical examination found pus from the external urethral ostium, redness,
swollen, external urethral ostium pain, and fever. What is the diagnosis for the case
above ?
A. Sifilis
B. Limfogranuloma venerum
C. Ulkus molle
D. Ulkus durum
E. Gonorrhoe

24. A woman (25 y.o.) is brought to the hospital with a history of sexual contact + 3 days
ago. Ulcer appear, disappear without treatment. Suddenly, two weeks later appeared red
spots spread throughout her body. What is the diagnosis for this case ?
A. Gonorrhoe
B. Limfogranuloma venerum
C. Sifilis
D. HIV/AIDS
E. Herpes Simplex Virus (HSV)

25. Toxoplasma gondii can be transmitted via ..........


1) Oral
2) Blood or organs
3) Transplacental transmission
4) Inhaling

26. The following statements are true about treatment regimens for Helicobacter pylori,
EXCEPT ..........
A. Omeprazole (20 mg bid) + Clarithromycin (500 mg bid) + Metronidazole (500 mg
bid)

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B. Omeprazole (20 mg bid) + Clarithromycin (500 mg bid) + Chloramphenicol (1 g
bid)
C. Omeprazole (20 mg bid) + Bismuth Subsalicylate (2 tabs qid) + Tetracycline HCl
(500 mg qid) + Metronidazole (500 mg tid)
D. Omeprazole (20 mg bid) + Amoxicillin (1 g bid)
E. Omeprazole (20 mg bid) + Clarithromycin (500 mg bid) + Tinidazole (500 mg bid)

27. A boy (12 y.o.) is brought to the polyclinic by his mother because of his fever 14 days.
Initially fever is not high, but over time the higher. Constipation (+). On physical
examination found conscious, temperature = 38.7ºC, pulse = 100 bpm, respiratory rate =
20 times/minutes, dirty tongue with hyperemia edge. The results of supportive
examination are most appropriate to describe the career diagnosis of these patient is
..........
A. There are O, Vi, and H titer regardless of it’s value
B. Increase in titer doubled
C. O titer 1 : 160
D. Vi titer 1 : 160
E. H titer 1 : 160

28. A man (35 y.o.) comes to the hospital with diarrhea that doesn’t recover since 6 weeks
ago. Also with 6 kg weight loss in 1 month. Before that, he was injecting drug users and
like alternately syringe among fellow addicts. On physical examination found weight =
45 kg, there are white patches on the oropharynx, and enlarged lymph nodes in the neck,
armpit, and groin. On the laboratory examination found CD4+ = 180/mL. What is the
most probable diagnosis for this case ?
A. Oral candidiasis
B. Chronic diarrhea
C. Lymphadenopathy
D. AIDS
E. Sifilis

29. A man (30 y.o.) comes to the hospital with diarrhea approximately 1 last month. 10 kg
weight loss in 2 months. He had a history of injecting drug use. On physical examination

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found generalized lymphadenitis and oropharyngeal candidiasis. The supportive
examination that can be used to enforce diagnosis of this case is ..........
A. Dark-field microscope
B. TPHA, VDRL
C. Western blot + ELISA
D. Wassermann test
E. Tzanck test

30. A woman (40 y.o.) comes to the hospital with flour albus. On the pap smear examination
found koilocyte cells and moderate dysplasia. The diagnosis of this case is ..........
A. HIV
B. HBV
C. HSV
D. HPV
E. VZV

 GOOD LUCK 

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