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    Pathophysiology of Ischemic Stroke Final

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    AcohCChao
    This document discusses the pathophysiology of ischemic stroke. It identifies predisposing factors like age, heredity, and prior health conditions that increase risk. Precipitating factors include hypertension, smoking, diabetes, and heart conditions that can lead to atherosclerosis and formation of plaque in arteries. When plaque deposits cause thrombosis and blockage of major vessels, it cuts off blood flow and oxygen to parts of the brain, causing tissue hypoxia and cellular starvation. If not managed, this continued ischemia can lead to further compression of brain tissues, coma, cerebral death, and ultimately systemic failure and death. Proper management with palliative care and interventions to restore perfusion may allow for poor improvement but a better prognosis.

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    Pathophysiology of Ischemic Stroke Final

    Uploaded by

    AcohCChao
    6K views3 pages
    This document discusses the pathophysiology of ischemic stroke. It identifies predisposing factors like age, heredity, and prior health conditions that increase risk. Precipitating factors include hypertension, smoking, diabetes, and heart conditions that can lead to atherosclerosis and formation of plaque in arteries. When plaque deposits cause thrombosis and blockage of major vessels, it cuts off blood flow and oxygen to parts of the brain, causing tissue hypoxia and cellular starvation. If not managed, this continued ischemia can lead to further compression of brain tissues, coma, cerebral death, and ultimately systemic failure and death. Proper management with palliative care and interventions to restore perfusion may allow for poor improvement but a better prognosis.

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    This document discusses the pathophysiology of ischemic stroke. It identifies predisposing factors like age, heredity, and prior health conditions that increase risk. Precipitating factors include hypertension, smoking, diabetes, and heart conditions that can lead to atherosclerosis and formation of plaque in arteries. When plaque deposits cause thrombosis and blockage of major vessels, it cuts off blood flow and oxygen to parts of the brain, causing tissue hypoxia and cellular starvation. If not managed, this continued ischemia can lead to further compression of brain tissues, coma, cerebral death, and ultimately systemic failure and death. Proper management with palliative care and interventions to restore perfusion may allow for poor improvement but a better prognosis.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    6K views3 pages

    Pathophysiology of Ischemic Stroke Final

    Uploaded by

    AcohCChao
    This document discusses the pathophysiology of ischemic stroke. It identifies predisposing factors like age, heredity, and prior health conditions that increase risk. Precipitating factors include hypertension, smoking, diabetes, and heart conditions that can lead to atherosclerosis and formation of plaque in arteries. When plaque deposits cause thrombosis and blockage of major vessels, it cuts off blood flow and oxygen to parts of the brain, causing tissue hypoxia and cellular starvation. If not managed, this continued ischemia can lead to further compression of brain tissues, coma, cerebral death, and ultimately systemic failure and death. Proper management with palliative care and interventions to restore perfusion may allow for poor improvement but a better prognosis.

    Copyright:

    © All Rights Reserved
    Download as DOCX, PDF, TXT or read online from Scribd
    Download as docx, pdf, or txt
    of 3

    Pathophysiology of Ischemic Stroke

    Predisposing Factors: Precipitating Factors:

    1) Age ۞ 1) Hypertension ۞

    2) Heredity ۞ 2) Cigarette Smoking

    3) Race 3) Diabetes Mellitus ۞

    4) Sex ۞ 4) Carotid or other Artery Disease ۞

    5) Prior Stroke, TIA or heart attack ۞ 5) Atrial Fibrillation

    6) Socioeconomic Factors ۞ 6) Other heart disease


    7) Sickle cell disease
    8) Undesirable levels of cholesterol
    9) Poor diet ۞
    10) Physical inactivity
    11) Obesity
    12) Alcohol Abuse
    13) Drug Abuse

    Atherosclerosis

    Formation of Plaque deposits

    Thrombosis

    Occlusion by major vessel

    CEREBRAL
    HYPOPERFUSION

    Impaired distribution of
    oxygen and glucose

    Tissue hypoxia and cellular


    starvation

    Cerebral Ischemia

    Initiation of ischemic
    cascade
    TRANSIENT ISCHEMIC
    ATTACK

    Cerebral edema

    Vascular Congestion

    Compression of tissue

    Increased intracranial

    Impaired perfusion and


    function

    CEREBRUM has 2 Hemispheres CEREBELLUM BRAINSTEM

    Parietal Lobe Temporal Lobe Occipital Lobe  Muscle  Heart Rate


    Frontal Lobe
    Coordination  Blood Pressure
     Balance  Breathing
    Problem in Problem in  Hearing  Vision  GI function
     Movement  Sensory  Smell  Consciousness
     Executive Information  Memory
    Function  Languages
     Facial
    Recognition
    If MANAGED: If NOT managed:

    Palliative care-
    Frequent vital sign and
    neurovital signs, intubation, Continued insufficiency of
    mechanical ventilation, blood flow
    vasodilators, osmotic
    diuretics, ventriculostomy,
    ICP monitoring Further compression of
    tissues

    Poor cerebral perfusion


    Coma

    Poor improvement
    Cerebral Death

    POOR PROGNOSIS
    Cessation of physiologic
    functions
    (Main Body System)

    Systemic Failure

    DEATH

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