Beta Glucan Interactions

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Are there any interactions with medications?

emedicinehealth.com/beta_glucans-page3/vitamins-supplements.htm

A
Beta Glucans
Indomethacin
Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.
Taking beta -glucans with the drug indomethacin might increase the risk developing for life-threatening
side effects to indomethacin. Until more is known about this potential interaction, be cautious when
taking beta -glucans with indomethacin.

Medications for high blood pressure (Antihypertensive drugs)


Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.
Beta-glucans might decrease blood pressure in some people. Taking beta-glucans along with
medications used for lowering high blood pressure might cause your blood pressure to go too low.
However, it is not known if this is a big concern. Do not take too much beta-glucans if you are taking
medications for high blood pressure.

Some medications for high blood pressure include captopril (Capoten), enalapril (Vasotec), losartan
(Cozaar), valsartan (Diovan), diltiazem (Cardizem), Amlodipine (Norvasc), hydrochlorothiazide
(HydroDiuril), furosemide (Lasix), and many others

Medications that decrease the immune system (Immunosuppressants)


Interaction Rating: Moderate Be cautious with this combination.
Talk with your health provider.
Beta-glucans increase the immune system. By increasing the immune system, beta-glucans might
decrease the effectiveness of medications that decrease the immune system.

Some medications that decrease the immune system include azathioprine (Imuran), basiliximab
(Simulect), cyclosporine (Neoral, Sandimmune), daclizumab (Zenapax), muromonab-CD3 (OKT3,
Orthoclone OKT3), mycophenolate (CellCept), tacrolimus (FK506, Prograf), sirolimus (Rapamune),
prednisone (Deltasone, Orasone), corticosteroids (glucocorticoids), and others.

Dosing considerations for Beta-glucans.


The following doses have been studied in scientific research:
BY MOUTH:

For high cholesterol: 7.5 grams twice daily beta glucans fiber from yeast added to juice has
been used. Barley-derived beta glucans have also been used in doses of 3-10 grams/day.

INTRAVENOUS:
Healthcare providers give beta glucans intravenously (IV) for HIV infection, to extend life in
patients with cancer, and to prevent infection in certain patients undergoing surgery.

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