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and learning tool for facilitating clinical likely and alternate hypotheses for all (labeled as P2), such as lateral thigh pain,
reasoning within the patient encounter areas of symptoms. The tool helps prior- also might increase, thereby suggesting
and clinical case analysis in one physical itize and focus intervention strategies at a the 2 areas of symptoms are related.25
therapy education program. This case dose that is likely to be effective and
report describes: (1) the mentee’s man- well-tolerated by the patient, minimizing A novice physical therapist might mistak-
agement and use of evidence in a patient the potential to irritate painful structures enly assume that patients will indicate all
case and (2) the teaching and learning or exacerbate the condition while maxi- areas of symptoms on a body chart and
occurring in the clinical reasoning mizing the opportunity to understand that any other body region is symptom-
process. the patient’s problem and achieve the free.2 Additionally, a novice physical
patient’s goals.27 The SCRIPT also may therapist might limit gathering the his-
Case Description help identify potential pathologies out- tory and body chart information to only
To our knowledge, the only clinical rea- side the scope of physical therapist prac- one area of symptoms.2 Reasons for this
soning tool published in the peer- tice that need to be screened for and decision could include time limitations,
reviewed literature is used in a pediatric ruled out. When the standard of screen- an attempt to focus on the areas of symp-
residency.24 Other clinical reasoning ing for a diagnostic hypothesis is toms for which the patient was referred
forms published in textbooks are unknown, a physical therapist should for physical therapy, or to mitigate a
detailed, yet lengthy,21,25 potentially pos- generate appropriate diagnostic ques- sense of being overwhelmed in complex
ing challenges to utilizing the form dur- tions and search the professional litera- cases or cases with multiple areas of
ing a typical patient encounter, and may ture for best-evidence screening symptoms. This rather limited approach
be more useful retrospectively. strategies.11 could hinder the physical therapist’s abil-
ity to recognize relationships between
In 1994, the Army-Baylor University Doc- Section I: Guiding Hypothesis areas of symptoms2 or patterns indicative
toral Fellowship Program in Orthopaedic Generation and Differential of nonmusculoskeletal conditions, such
Manual Physical Therapy faculty began Diagnosis as systemic illness. Pattern recognition
developing an expedient tool using a Section I guides the mentee’s hypothesis may assist experienced physical thera-
combination of sources, including work- development and consideration of differ- pists with early hypothesis formation.28
sheets from other programs, clinical ential diagnoses early in the patient- However, a physical therapist working
experience, and examples from a variety physical therapist interaction. After solely from pattern recognition of com-
of unpublished sources, with feedback establishing the patient’s profile, includ- mon causes in cases such as this might
from fellows-in-training and other fac- ing age, sex, work, and recreational hab- assume21 that all cases of back and con-
ulty. This tool, titled the SCRIPT, was its, the mentee gathers information on all current leg pain are of the same origin
designed primarily to develop clinical areas of symptoms by completing a body and overlook other potential sources of
reasoning skills during a patient encoun- chart or symptom map. Accuracy and unrelated leg pain, such as tumor, deep
ter, appropriately tailor examination and detail of the body chart, including the venous pathology, peripheral neuritis, or
intervention strategies, promote diagnos- location, behavior, character or quality, a distinct local musculoskeletal problem.
tic accuracy, and assist with planning and intensity of all symptoms, are crucial Expert clinicians may use pattern recog-
subsequent patient encounters (eAppen- to understanding the patient’s baseline nition in the differential diagnosis pro-
dix, available at ptjournal.apta.org). The presentation and are the foundation for cess but also must maintain an open
form is completed for initial patient early comprehensive diagnostic hypoth- mind and a willingness to generate, doc-
encounters during formal one-on-one esis generation. ument, and systematically test multiple
mentorship sessions between the fellow- alternative hypotheses.7,18,21,29,30
in-training (mentee) and the fellowship-
The mentee places a check mark over
trained faculty (mentor) and during sub- The flow of the typical formal mentor-
potentially relevant areas on the body
sequent encounters to reflect on initial ship session is illustrated in Figure 1.
chart that are screened and determined
hypothesis formation and decision mak- After completing the body chart, the first
to be asymptomatic. To help prevent
ing.26 The SCRIPT is a tool that provides of two 5- to 10-minute pauses occurs
misunderstanding, the mentee touches
structure for the mentee and insight into away from the patient to allow the men-
the patient or points to the body region
the mentee’s clinical reasoning process. tee to complete section I of the SCRIPT.
and asks the patient appropriate screen-
The SCRIPT also facilitates individual These pauses are critical to clinical men-
ing questions such as, “Do you have any-
self-reflective practice and guides patient torship, enabling the mentee to reflect
thing that is not normal or recently
case discussions between physical ther- on action,6 plan the remaining examina-
changed here?”25 Determining and doc-
apists in clinical and educational settings. tion, ask the mentor questions, and gain
umenting relationships between areas of
symptoms on the body chart is helpful to guidance. This approach also provides
The Process hypothesis formation and the differential an opportunity for the mentor to gain
The SCRIPT facilitates planning and exe- insight into the mentee’s clinical reason-
diagnosis process. For example, when a
cuting a comprehensive, yet well- ing, reinforce their positive decisions,
“primary concern” area of symptoms
tolerated, history taking and examination and make suggestions and pose ques-
(labeled as P1), such as mid-lumbar pain,
by delineating current symptom inten-
increases, a secondary area of symptoms
sity and behavior, as well as the most
likely, less likely, and remote hypotheses nature of the disorder is a multifactorial
in section II of the SCRIPT. The mentor judgment based on the mentee’s percep-
reviews the form with the mentee, pro- tion of unique factors associated with the
viding immediate feedback and helping probable condition, such as typical mus-
to refine or provide additional hypothe- culoskeletal origin, nontypical presenta-
ses.31 The mentor ensures that the men- tion requiring screening, complex disor-
tee has a plan to effectively utilize the ders (eg, whiplash, acute radiculitis), and
remaining patient history to refine and personal factors (eg, being a single
prioritize competing hypotheses with working parent, exhibiting high fear-
carefully selected and formulated ques- avoidance behavior).25,32,37 Stage refers
tions and to determine likely symptom to the duration of symptoms, classified as
behavior during the physical examina- acute, subacute, or chronic or a combi-
tion and intervention. Hypotheses nation of stages (eg, acute and
derived and prioritized during the his- chronic).25,32 Stage can be an important
tory taking are subsequently examined factor directly related to the nature of the
with appropriate tests and measures, and problem, particularly in disorders with
later by the patient’s response to inter- healing tissues or inflammatory pro-
vention, thereby requiring both deduc- cesses. Stability may be characterized as
tive (analytical) and inductive thinking. a sign or symptom improving, worsen-
ing, or not changing over the course
During a mentorship session, the second of the present episode or previous
planned pause occurs at the conclusion episodes.25,32
of the history taking for the mentee to
complete sections II, III, and IV of the Section III: Considering
SCRIPT. Additional Contributing Factors
Completing section III prompts the men-
Section II: Making Clinical tee to consider additional factors contrib-
Judgments uting to the patient’s condition, such as
Section II requires judgments on the con- poor conditioning or psychosocial fac-
structs of severity and irritability of symp- tors, that may change the prognosis or
toms and nature, stage, and stability of require therapeutic attention. These fac-
the disorder, collectively referred to as tors are considerations but should not be
Figure 1.
Flow diagram of how to use the Systematic SINSS.25 The SINSS, initially described by overly weighted in the differential diag-
Clinical Reasoning in Physical Therapy Maitland and elaborated on by various nosis process. A patient with decondi-
(SCRIPT) tool during a mentorship session. other authors,25,32,33 are evaluated for tioning or psychosocial issues would
each symptomatic area, as different areas have as many possible sources of symp-
of symptoms may have different symp- toms as a patient who is more physically
tom behavior and possibly different ori- fit or emotionally stable, and those pos-
tions to highlight alternatives in
gins (Fig. 2). The SINSS are determined sible sources should be systematically
reasoning.
by analyzing information gathered dur- considered and ruled out.38 This patient,
ing the history taking.25,32,33 This con- however, did not display contributing
The mentee lists all structures that must
cept helps determine the extent and factors that required additional
be considered as possible sources of the
vigor of the examination and treatment consideration.
patient’s symptoms, to include joints and
that are likely to be well-tolerated.27,33
bony structures; muscles, tendons, and
soft tissue structures; structures that may
For example, if a mentee judges a Sections IV and V: Planning the
patient’s symptoms to be severe (high Examination
refer symptoms into the area of concern;
intensity) and irritable (easily provoked Section IV provides a flexible framework
and other structures or conditions that
and persisting), the examination should for planning the examination. The men-
must be considered or ruled out, such as
be limited to the first onset or increase of tee refers to the hypotheses in section I
visceral pathology, infections, space-
symptoms, and the overall number of and reprioritizes the most likely hypoth-
occupying lesions, and systemic non-
examination procedures should be eses based on information obtained dur-
musculoskeletal pathology. This proac-
reduced accordingly.25 Conversely, a ing the remainder of the history taking.
tive planning makes explicit the
patient whose symptoms display mild Tests and measures typically prioritized
connections between thinking and
severity and irritability might tolerate and selected for the initial examination
future actions.
examination including provocative diag- provide essential evaluation of the most
nostic special tests, manual examination likely hypotheses and rule out potentially
After completing section I, the mentee
to end of range of motion (ROM), and serious conditions (Fig. 3). The vigor of
formalizes their differential thought by
combined or repeated motions.34 –36 The the examination is strongly influenced by
generating and prioritizing the most
II. INFLUENCE OF THE SYMPTOMS ON THE EXAM. Detailed by Area of Symptoms rately determine the patient’s response
as Mapped on Body Chart . to intervention. In section VIII, the men-
Px Severity Irritability Nature Stage Stability Limit tee records prognostic information. If a
Exam patient is not responding according to
P1 Moderate Mild MS K, postsurgical, Chronic Not changing N
degenerative
the prognosis evidence and the mentee’s
P2 Mild– Mild MSK, nerve, possible Chronic Worsening N clinical experience, further consider-
moderate systemic disease ation of alternate hypotheses, additional
contribution examination, or more formal screening
P3 Mild– Mild MSK, nerve, possible Chronic Worsening N may be warranted. The mentee’s ability
moderate systemic disease
to assess a patient’s response to interven-
contribution
Mild Mild (Healing, fragile Acute, Improving Yes= Y
tion in order to test diagnostic hypothe-
Moderate Moderate tissues, inflammatory, subacute, Worsening No=N ses, combined with the ability to exam-
Severe Severe psychosocial) chronic Not changing ine and treat patients over multiple
Non-MSK/MSK/both Acute on clinical sessions, should improve diag-
chronic nostic accuracy, particularly when clini-
Subacute on
chronic
cal reasoning is utilized throughout the
What will be the vigor of your exam? P1 P2 P3 Do the nature, diagnosis, or
episode of care.10,11
comorbidities warrant special
Examine to first onset or change in pain caution for exam or treatment? Application of the Process
Examine to end of active range of What? Y/N
We present a patient case where the
motion/ACTIVE limit (eg, trauma/red
X SCRIPT guided the clinical reasoning
flags/instability/pathological process)
No process during a patient encounter with
Examine to end of passive range of Which symptoms will be desirable to a 64-year-old retired man who was
motion/PASSIVE limit reproduce? referred by a physician for physical ther-
Back pain (P1) and peripheral
apy with a diagnosis of axial back pain.
symptoms (P2 and P3)
Examine with OVERPRESSURE Do you expect a comparable sign to
The patient reported a primary com-
sufficient to determine end feel be EASY or HARD to reproduce? plaint of chronic lower back pain (LBP)
Easy in lumbar spine, hard in periphery and a secondary complaint of bilateral
Use sustained, repeated, or combined What do you expect to be treating? plantar foot tingling. The care of this
movements (Circle one) patient met Health Insurance Portability
PAIN and Accountability Act (HIPAA) require-
X X
RESISTANCE
R ESISTANCE RESPECTING PAIN ments of the institution for disclosure of
RESISTANCE protected health information.
IV. PLANNED EXAM PROCEDURES: Prioritize based on most likely hypotheses and response to lumbar intervention to help
SINSS. determine the relationship between the
Day/Visit 1 Day/Visit 2 Day/Visit 3 LBP and foot tingling.
Lumbar AROM, LE MNSI: inspection of feet, Repeated motions to assess
neurological exam, SLR, vibration for centralization/
Interview and physical examination find-
palpation exam of lumbar Slump test for neural tension peripheralization
spine, segmental mobility of symptoms Clear hip/SIJ ings are documented in the patient
lumbar spine Prone knee bend to assess record, and key findings are marked with
anterior hip structure asterisk signs to denote them as impor-
flexibility tant parts of the baseline presentation.
Figure 3. These key findings are frequently reex-
Section IV of the Systematic Clinical Reasoning in Physical Therapy (SCRIPT). SINSS⫽severity, amined to determine patient response to
irritability, nature, stage, stability; AROM⫽active range of motion; LE⫽lower extremity; examination and treatment. These key
SLR⫽straight leg raise; MNSI⫽Michigan Neuropathy Screening Instrument, SIJ⫽sacroiliac baseline findings are recorded in section
joint. V of the SCRIPT (Fig. 5).
I. WHAT AREAS/STRUCTURES MUST BE CONSIDERED AS POSSIBLE for diabetic PND.36 A score of ⱖ2 has a
SOURCE(S) OF SYMPTOMS? specificity of 83% (95% confidence inter-
Joints Muscles, Pain- OTHER P1: central val⫽75%, 89%) and a positive likelihood
low back
and bony tendons, producing structures pain; achy, ratio of 3.9 (95% confidence inter-
structures and other structures or stiff, deep val⫽2.5, 6.1), suggesting that further
UNDER soft tissue that may conditions 2–10/10
Resting quantitative neurological testing was
the area UNDER REFER that must pain 2/10
of and IN the into the be appropriate.36
symptoms area of area of considered
symptoms symptoms or ruled Based on the literature, the mentee
out planned to administer the MNSI at the
-Bilateral -Lower -Lower - Lower following visit to further differentiate the
lower lumbar thoracic extremity P2 (left genesis of the peripheral symptoms
lumbar paravertebral spine vascular foot) and
facet muscles -Upper - GI system P3 (right (Fig. 7). Subsequent examination demon-
foot): strated a reduced ankle reflex on the
joints -Bilateral lumbar - GU system bilateral,
-Bilateral quadratus spine - Space- foot right and absent vibratory sense at both
lower lumborum Mid occupying tingling, ankles, resulting in an MNSI score of 2.5
deep,
lumbar muscles lumbar lesion constant, and the need for further screening. The
vertebral -Bilateral spine (tumor) 2–5/10 diagnostic gold standard for diabetic
joints proximal -Upper, - Spinal Resting
-Bilateral gluteal pain 2/10 PND is electromyography and nerve con-
mid, and infection
ilium muscles lower
duction study (EMG/NCS) testing.34 Due
-Sacrum -Bilateral foot lumbar to the patient’s complaints of worsening
-Bilateral intrinsic disks lower extremity neurological symptoms,
sacroiliac muscles -Bilateral the physical therapist communicated
joints -Bilateral sacroiliac with the patient’s primary care provider,
-Bilateral plantar joints
fascia
who ordered EMG/NCS testing.
hindfoot -Bilateral
joints -Bilateral hip joints
-Bilateral lower -Bilateral The EMG/NCS testing demonstrated mild
tarsal extremity talocrural demyelinating PND affecting the sensory
joints peripheral joints and motor fibers in the lower extremi-
-Bilateral nerves ties, as well as evidence of chronic bilat-
tarsometatarsal (tibial,
joints deep/
eral L5 and S1 radiculopathies that did
-Bilateral superficial not warrant surgical intervention. This
metatarsal fibular, knowledge helped the mentee deter-
phalangeal medial/ mine the likely clinical diagnoses and
joints lateral overall prognosis (Fig. 7). Physical ther-
plantar) apy treatment would likely influence the
Most Likely Hypotheses: Less Likely Hypotheses: Remote Hypotheses: patient’s chronic LBP more than the
Chronic central lower Spinal stenosis with Space-occupying chronic neurological symptoms. How-
lumbar dysfunction neurogenic claudication lesion in the lumbar ever, understanding the contributions of
with bilateral Myofascial pain status post spine
the diabetic PND to the patient’s symp-
radiculopathy/radiculitis, lumbar surgery with bilateral Lower extremity or
most likely of S1 chronic neural tension abdominal vascular toms enabled the mentee to provide
nerve root symptoms pathology appropriate patient education, devise a
Chronic central lower Referred pain from treatment plan respective of the patient’s
lumbar dysfunction viscerogenic pathology comorbidity and reconnect the patient
with peripheral Spinal infection with his primary care provider for con-
neuropathic disease tinued medical management.
(polyneuropathy or
mononeuropathy)
In accordance with the Guide to Physi-
Figure 4. cal Therapist Practice,37 the appropriate
Section I of the Systematic Clinical Reasoning in Physical Therapy (SCRIPT). clinical care for this patient included
GI⫽gastrointestinal, GU⫽genitourinary, P1⫽primary area of symptoms, P2⫽secondary area treating the LBP consistent with best-
of symptoms, P3⫽tertiary area of symptoms. evidence strategies and referring the
patient for further evaluation of his PND.
The data from the SCRIPT helped guide
clinical reasoning and plan management
betic neuropathy, including foot and ment (MNSI), consisting of a foot inspec- throughout the episode of care.
lower limb inspection and sensory test- tion, ankle reflexes, and vibration per-
ing.35 The literature indicated that the ception, has been validated in the type 2
Michigan Neuropathy Screening Instru- diabetic population as a screening tool
terns of a manual physical therapist and may be of benefit to have a third planned All authors provided concept/idea/project
utilizes verbiage best known from Mait- pause after the examination to discuss design and writing. Dr Deyle and Dr Baker
land’s work.25 Additionally, utilizing a key findings, reprioritize diagnostic provided project management. Dr Jensen
tool such as the SCRIPT requires dedi- hypotheses, and plan treatment. This provided consultation (including review of
manuscript before submission).
cated time and effort, which may prove third planned pause may be well worth
to be obstacles to its utilization in typical the additional cost of time for novices or DOI: 10.2522/ptj.20150482
clinical practice. Our program allots 90 mentees who the mentor identifies as
minutes to an initial evaluation in order struggling with a particular patient
to allow for the 2 planned pauses away encounter. Lastly, although the SCRIPT
from the patient and the ongoing discus- attempts to concisely marry the
sion between the mentee and mentor hypothetico-deductive reasoning strate-
during the examination and treatment. It gies with narrative reasoning, the
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eAppendix.
Systematic Clinical Reasoning in Physical Therapy (SCRIPT) Blank Forma
II. INFLUENCE OF THE SYMPTOMS ON THE EXAM. Detailed by Area of Symptoms as Mapped on Body Chart.
Mild Mild (Healing, fragile tissues, Acute, subacute, chronic Improving 1 YesⴝY
Moderate Moderate inflammatory, Acute on chronic Worsening 2 NoⴝN
Severe Severe psychosocial) Subacute on chronic Not changing
Non-MSK/MSK/both
(Continued)
eAppendix
Continued
III. INFLUENCING FACTORS: Are there contributing factors that need to be addressed with this patient? (check all that apply)
IV. PLANNED EXAM PROCEDURES: Prioritize based on most likely hypotheses and SINSS.
V. EXAM FINDINGS
Important baseline findings from patient history Important baseline exam findings:
1st
VIII. PROGNOSIS
What is the natural history of the disorder?
At the next visit, what treatment will you choose if the patient is:
a
Developed for Army-Baylor University Doctoral Fellowship in Orthopaedic Manual Physical Therapy. Px⫽area of symptoms, P1⫽primary area of symptoms,
P2⫽secondary area of symptoms, P3⫽tertiary area of symptoms, P4⫽quaternary area of symptoms, MSK⫽musculoskeletal; SINSS⫽severity, irritability,
nature, state, stability. The Systematic Clinical Reasoning in Physical Therapy (SCRIPT) may not be used or reproduced without written permission from the
authors.