Computer Science Education
Computer Science Education
Vasant Honavar
Artificial Intelligence Research Laboratory
Department of Computer Science
Bioinformatics and Computational Biology Graduate Program
Computational Intelligence, Learning, & Discovery Program
Iowa State University
[email protected]
www.cs.iastate.edu
www.cild.iastate.edu
www.bcb.iastate.edu
Talk given at the meeting of the Iowa Undergraduate Computer Science Consortium. Drake University, October 23, 2004.
Copyright Vasant Honavar, 2004.
Outline
Representative Problems
Inference of tree of life from DNA sequence data
Characterization of protein sequence – structure –
function relationships e.g., discovery of sequence
and structural correlates of protein-protein
interactions
Genetic network inference from gene expression data
Inference of metabolic pathways
Modeling and prediction of cellular processes
Modeling host-pathogen interactions
Bioinformatics
Program History
Research areas
Bioinformatics
Functional and structural genomics
Genome evolution
Macromolecular structure and function
Metabolic and regulatory networks
Mathematical biology
Biological statistics
Bioinformatics And Computational Biology
Program Overview
One of the first Bioinformatics Ph.D. programs in the US
Over 60 Ph.D. students, one of the largest and strongest
Bioinformatics Ph.D. programs in the US
Over 72 BCB faculty in 14 different departments
$30 million in grants between July 1999-July 2004
2 major training grants
(NSF-IGERT, $2.7M; USDA-MGET, $1.7M)
Bioinformatics Summer Institute (NSF-NIH)
Bioinformatics and
Computational Biology
Interdisciplinary Training
Background & ramp-up courses
Core courses in computational molecular biology and
bioinformatics
Bioethics courses & training sessions
Electives in Statistics, Computer Science, Biology
Faculty Research Seminar
Student Seminar
Computational molecular biology seminars and
symposia
Bioinformatics and
Computational Biology
Interdisciplinary Research
Research exploration rotations
Joint mentoring -- `Wet’ and ‘dry’ lab research
experiences and mentoring by a major and co-
major professor (from computational and
biological sciences)
International and industrial internships
Representative Computational Biology research
Computational approach
to prediction of protein-
protein interface
residues from protein
sequence
Representative bioinformatics research
M Query S(θ,D,O)
Mapping
Learning Algorithm
O
Ontology O Ontology O’
How?
What should a Computer Scientist know?