Unanswered: (Correct Answer)

5/15/2018 Score Report: BRC-LS-Weekly Test 2-MB/AB/WB- 16th July 2017
1)
A father said to his son, "I was as old as you are at the present at the
time of your birth". If the father's age is 38 years now, the son's age
five years back was:
A. 14 yrs (Correct Answer)
B. 19 yrs
C. 33 yrs
D. 38 yrs
Unanswered
2)
3/8 of 168 * 15 / 5 + X = 549 / 9 + 275
A. 107
B. 147 (Correct Answer)
C. 10
D. 296
Unanswered
3)
A person crosses a 600 m long street in 5 minutes. What is his speed
in km per hour?
A. 3.6
B. 7.2 (Correct Answer)

C. 8.4
D. 10
Unanswered
4)
Under experimental conditions, cells grown in a medium containing
thymine would incorporate thymine into their DNA. If cells grown for a
number of generations in a medium containing radioactive thymine
were removed from this medium and allowed to replicate once using
thymine that was not radioactive, what percent of these cells would
now be radioactive?
A. 0%
B. 25%
C. 50%
D. 100% (Correct Answer)
Unanswered
https://www.proprofs.com/quiz-school/quizreport.php?title=brclsweekly-test-2mbabwb-16th-july-2017&sid=170316743 2/11
5)
A new microorganism was isolated from polar region. Upon studying
the nucleotide composition it was found to contain
A G C T
30% 40% 20% 10%
What type of molecule acts as the genetic material in this organism.
A. Double stranded linear DNA
B. Double stranded circular DNA
C. Single stranded linear DNA (Correct Answer)

D. Single stranded truncated RNA
Unanswered
6)
A double-stranded DNA molecule contains 20% adenine. Determine
the number of cytosine bases if the DNA molecule is 1 μm long.
A. 1764 (Correct Answer)
B. 5882
C. 2941
D. 4000
Unanswered
7)
The following are some examples of problems that can occur during
DNA replication. Identify the correctly matched defective enzyme or
enzymes that would cause each problem.
1. Mismatched base pairs are found in the newly synthesized DNA –
DNA polymerase 5' – 3' exonuclease activity
2. Replication is not initiated – DNA A, HU & IHF proteins
3. RNA bases are found in the newly synthesized DNA - DNA
polymerase I
A. Only 1
B. Both 1 & 2
C. Only 3
D. Both 2 & 3 (Correct Answer)
Unanswered
8)
Xeroderma pigmentosum in human is associated with a mutation in
A. Photoreactivation
B. Nucelotide excision repair (Correct Answer)

C. Base excision repair
D. Mismatch repair
Unanswered
9)
Telomeres are found in
A. E.coli
B. Bacteriphage T2
C. Mouse brain cells (Correct Answer)

D. S. pneumoniae
Unanswered
10)
Which of the following is a DNA palindrome? (Note: Only the top
strand of the DNA is shown.)
A. 5’-GGGAAA-3’
B. 5’-CGCCGC-3’
C. 5’-GGGGGG-3’
D. 5’-AATATT-3’ (Correct Answer)
Unanswered
11)
The ion channel that opens in response to acetylcholine is an
example of a ____________ signal transduction system.
A. G protein
B. Ligand gated (Correct Answer)

C. Serpentine receptor
D. Voltage gated
Unanswered
12)
Which of the following statements concerning receptor enzymes is
correct?
A. They are not usually membrane-associated proteins.
B. They contain an enzyme activity that acts upon a

cytosolic substrate. (Correct Answer)
C. They contain an enzyme activity that acts upon the

extracellular ligand.
D. They have an active site on the extracellular side of

the membrane.
Unanswered
13)
Protein kinase A (PKA) is:
A. activated by covalent binding of cyclic AMP.
B. affected by cyclic AMP only under unusual

circumstances.
C. allosterically activated by cyclic AMP. (Correct

Answer)
D. D) competitively inhibited by cyclic AMP.
Unanswered
14)
Calmodulin is a:
A. allosteric activator of calcium-dependent enzymes.
B. allosteric inhibitor of calcium-dependent enzymes.
C. cell surface calcium receptor.
D. regulatory subunit of calcium-dependent enzymes.
D) competitively inhibited by cyclic AMP.. (Correct

Answer)
Unanswered
15)
The G-protein involved in visual signal transduction is:
A. transducin (Correct Answer)
B. arrestine
C. rhodopsin
D. a GTP protein
Unanswered
16)
Describe the role of G proteins in signal transduction
A. Signal molecule activates G-protein by exchange of
GDP by GTP, as a result either adenylyl cyclase or
phospholipase C is activated, which in turn increases
the level of ligands that open ion channels.
(Correct Answer)
B. They activates MAPK cascade
C. both a and b
D. none of above
Unanswered
17)
which one of the following statements does not

correctly describes G-protein?
A. Energy for their activity comes from GTP molecules
B. They become activated by interaction with ‘7-pass’

receptors
C. G-proteins are transmembrane receptor associated

protein
D. G-protein activation always increase the concentration

of cAMP. (Correct Answer)
Unanswered
18)
The size of the Saccharomyces cerevisiae genome is about 1.5x10^7
base pairs. Yeast, which uses 400 replication origins to replicate its
17 chromosomes, takes 30 minutes to complete S phase (replicate
its genome). Assume all replicons are the same size, initiate
replication at the same time during the cell cycle and are replicated at
the same rate. How fast does a yeast replication fork move.
A. 5000 nm/min/fork
B. 1250 nm/min/fork
C. 625 nm/min/fork
D. 212.5 nm/min/fork (Correct Answer)
Unanswered
19)
Telomerase adds 6 nucleotide repeats to the end of the
chromosomes called telomere. The telomeric repeat sequence of
tetrahymena is TTGGGG. The telomeric repeat sequence of yeast is
GTGTGT. Propagation of Tetrahymena chromosomes in yeast will
result in extension as follows:
A. TTGGGGTTGGGGTTGGGG (Correct Answer)
B. GTGTGTGTGTGTGTGTGT
C. GTGTGTTTGGGGGTGTGT
D. TTGGGGGTGTGTTTGGGG
Unanswered
20)
The following primer is placed in the replication bubble of a DNA (as
given in diagram ): 5'– GCUAUCG –3'. If the replication fork moves to
the right, the primer will be used to create
A. Leading Strand
B. Lagging Strand (Correct Answer)
C. Both leading and lagging strand
D. none of the above as orientation of primer is not

proper
Unanswered
21)
. response of a tissue almost stopped when exposed for prolonged
time to a chemical. After washing and leaving it for sometime, the
tissue started responding to the same concentration. The reason for
the reduced response is likely to be
A. Increase in apoptosis of a cell
B. increase in necrosis of a cell
C. Desensitization/Downregulation of a receptor
(Correct Answer)
D. Fixation of cells
Unanswered
22)
Which of the following statements concerning signal transduction by
the insulin receptor is not correct?
A. Binding of insulin to the receptor activates a protein

kinase.
B. Binding of insulin to the receptor results in a change in

its quaternary structure.
C. The receptor protein kinase activity is specific for

tyrosine residues on the substrate proteins.
D. The substrates of the receptor protein kinase activity

are mainly proteins that regulate transcription.
(Correct Answer)
Unanswered
23)
Which of the following is not involved in signal transduction by the β-
adrenergic receptor pathway?
A. cAMP synthesis
B. GTP hydrolysis
C. Protein Kinases
D. All are involved (Correct Answer)
Unanswered
24)
The average weight of A, B and C is 45 kg. If the average weight of A
and B be 40 kg and that of B and C be 43 kg, then the weight of B is:
A. 17kg
B. 20kg
C. 26kg
D. 31kg (Correct Answer)
Unanswered
25)
The Golgi apparatus is involved in
A. transporting proteins that are to be released from the
cell
B. packaging proteins into vesicles
C. altering or modifying proteins
D. producing lysosomes
E. all of the above (Correct Answer)
Unanswered
26)
Passage through pores in the nuclear envelope is restricted primarily
to
A. proteins, RNA, and protein-RNA complexes
(Correct Answer)
B. lipids and glycolipids
C. DNA and RNA
D. RNA and protein-carbohydrate complexes
E. marker proteins for the plasma membrane
Incorrect
27)
A researcher made an interesting observation about a protein made
by the rough ER and eventually used to build a cell's plasma
membrane. The protein in the membrane was actually slightly
different from the protein made in the ER. The protein was probably
changed in the
A. Golgi apparatus. (Correct Answer)
B. smooth ER.
C. mitochondrion.
D. nucleus.
E. chloroplast. (Your Answer)
Unanswered
28)
Blood group type A antigen is a complex oligosaccharide which
differs from H antigen present in type O individual by the presence of
terminal
A. Glucose
B. Galactose
C. N-acetyl galactosamine (Correct Answer)
D. Fucose
Unanswered
29)
A unique property of lysosomal proteins is that they
A. contain a stop-transfer sequence
B. operate only in alkaline environment
C. are enclosed in clathrin coated vesicles
D. are phosphorylated on mannose residues (Correct

Answer)
E. are modified by o-linked glycosylation of asparagines

residues
Unanswered
30)
The breakdown of glycogen into its energy-rich subunits is controlled
in vertebrates by a number of hormones, most notably
______________, which is secreted by the pancreas and _________
which is secreted by adrenal gland
A. Glucagon and Adrenaline
B. Glucagon and Epinephrine (Correct Answer)

C. Adrenaline and Epinephrine
D. Cortisol and Epinephrine
Unanswered
31)
Dye injected into a plant cell might be able to enter an adjacent cell
through a
A. tight junction.
B. microtubule
C. desmosome.
D. plasmodesma. (Correct Answer)

E. gap junction
Unanswered
32)
Lipid rafts are involved in signal transduction in cells. Rafts have
composition different from the rest of the membrane. Rafts were
isolated and found to have cholesterol to sphingolipid ration of 2:1.
The estimated size of the raft is 35 nm2. If the surface areas of
cholesterol is 40 Å2 and sphingolipid is 60 Å2, how many cholesterol
and sphingolipids are present in one raft?
A. 50 cholesterol: 25 sphingolipid (Correct Answer)

B. 200 cholesterol: 100 sphingolipid
C. 40 Cholesterol: 20 sphingolipid
D. 20 cholesterol: 10 sphingolipid
Unanswered
33)
When Lucifer yellow, a small dye, is injected into a neuron of the
retina, neighbouring neurons become rapidly labeled. If the retina is
incubated in dopamine prior to Lucifer yellow injection, only the
injected neuron becomes labeled. These findings suggest which of
the following?
Neurons of the retina communicate via gap junctions

Dopamine is transferred between cells via gap junctions
Dopamine decreases the permeability of gap junctions
A. I only
B. II only
C. III only
D. I and II only
E. I and III only (Correct Answer)

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5/15/2018 Score Report: BRC-LS-Weekly Test 2-MB/AB/WB- 16th July 2017

B. 147 (Correct Answer)

B. 7.2 (Correct Answer)

D. 100% (Correct Answer)

B. Double stranded circular DNA

C. Single stranded linear DNA (Correct Answer)

D. Both 2 & 3 (Correct Answer)

B. Nucelotide excision repair (Correct Answer)

C. Mouse brain cells (Correct Answer)

D. 5’-AATATT-3’ (Correct Answer)

B. Ligand gated (Correct Answer)

B. They contain an enzyme activity that acts upon a

C. They contain an enzyme activity that acts upon the

D. They have an active site on the extracellular side of

B. affected by cyclic AMP only under unusual

C. allosterically activated by cyclic AMP. (Correct

D. D) competitively inhibited by cyclic AMP.

B. allosteric inhibitor of calcium-dependent enzymes.

C. cell surface calcium receptor.

D. regulatory subunit of calcium-dependent enzymes.

D) competitively inhibited by cyclic AMP.. (Correct

which one of the following statements does not

A. Energy for their activity comes from GTP molecules

B. They become activated by interaction with ‘7-pass’

C. G-proteins are transmembrane receptor associated

D. G-protein activation always increase the concentration

D. 212.5 nm/min/fork (Correct Answer)

B. Lagging Strand (Correct Answer)

C. Both leading and lagging strand

D. none of the above as orientation of primer is not

A. Increase in apoptosis of a cell

B. increase in necrosis of a cell

A. Binding of insulin to the receptor activates a protein

B. Binding of insulin to the receptor results in a change in

C. The receptor protein kinase activity is specific for

D. The substrates of the receptor protein kinase activity

D. All are involved (Correct Answer)

D. 31kg (Correct Answer)

B. packaging proteins into vesicles

C. altering or modifying proteins

E. all of the above (Correct Answer)

C. DNA and RNA

D. RNA and protein-carbohydrate complexes

E. marker proteins for the plasma membrane

E. chloroplast. (Your Answer)

C. N-acetyl galactosamine (Correct Answer)

B. operate only in alkaline environment

C. are enclosed in clathrin coated vesicles

D. are phosphorylated on mannose residues (Correct

E. are modified by o-linked glycosylation of asparagines

A. Glucagon and Adrenaline

B. Glucagon and Epinephrine (Correct Answer)

D. Cortisol and Epinephrine

D. plasmodesma. (Correct Answer)

A. 50 cholesterol: 25 sphingolipid (Correct Answer)

Neurons of the retina communicate via gap junctions

E. I and III only (Correct Answer)

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