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Omeprazole

Omeprazole is a proton pump inhibitor used to treat conditions such as ulcers and gastroesophageal reflux disease. It works by inhibiting the hydrogen-potassium ATPase enzyme in gastric parietal cells, suppressing gastric acid secretion. Indications include short-term treatment of ulcers and GERD, long-term therapy for pathologic hypersecretory conditions, and eradication of H. pylori infections. Common adverse effects are headache, diarrhea, and abdominal pain. Nursing considerations include taking the drug before meals and reporting severe side effects.

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0% found this document useful (0 votes)
460 views2 pages

Omeprazole

Omeprazole is a proton pump inhibitor used to treat conditions such as ulcers and gastroesophageal reflux disease. It works by inhibiting the hydrogen-potassium ATPase enzyme in gastric parietal cells, suppressing gastric acid secretion. Indications include short-term treatment of ulcers and GERD, long-term therapy for pathologic hypersecretory conditions, and eradication of H. pylori infections. Common adverse effects are headache, diarrhea, and abdominal pain. Nursing considerations include taking the drug before meals and reporting severe side effects.

Uploaded by

BASHArn
Copyright
© Attribution Non-Commercial (BY-NC)
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOC, PDF, TXT or read online on Scribd
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DRUG NAME DOSAGE/FREQUE MECHANISM INDICATION CONTRAINDICA ADVERSE NURSING

NCY/ OF ACTION TION EFFECT CONSIDERATION


ROUTE

GENERIC NAME: DOSAGE: 90mg Gastric acid- Indicated for: Contraindicated CNS: Headache, C: Antisecretory
pump inhibitor: with dizziness, drug;
Omeprazole • Short-term
Suppresses hypersensitivity asthenia,
FREQUENCY: OD treatment of Proton pump
gastric acid to omeprazole or vertigo,
activeduodenal inhibitor
BRAND NAME: secretion by its components; insomnia,
ulcer; First-line H: IVTT
Losec (CAN) ROUTE: IVTT specific Use cautiously apathy, anxiety,
therapy in E: decrease
inhibition of the with pregnancy, paresthesias,
treatment of gastric acid
hydrogen- lactation. dream
DRUG heartburn or secretion
potassium abnormalities
CLASSIFICATION symptoms of C: Take the drug
ATPase enzyme Dermatologic:
: gastroesophageal before meals.
system at the Rash,
Antisecretory reflux disease Report severe
secretory inflammation,
drug (GERD); headache,
surface of the urticaria,
Proton pump • Short-term pruritus, worsening of
gastric parietal
inhibitor treatment of alopecia, dry symptoms, fever,
cells; blocks
active benign skin chills.
the final step of
gastric ulcer; GI: Diarrhea, K: Swallow the
acid
abdominal pain, capsules whole;
production. • GERD, severe
nausea, do not chew,
erosive
vomiting, open, or crush
esophagitis,
constipation, them.
poorly
responsive dry mouth,
symptomatic tongue atrophy
GERD; Respiratory: URI
symptoms,
• Long-term
cough, epistaxis
therapy:
Other: Cancer in
Treatment of
preclinical
pathologic
studies,
hypersecretory
back pain, fever
conditions
(Zollinger-Ellison
syndrome,
multiple
adenomas,
systemic
mastocytosis);
• Eradication of H.
pylori with
amoxicillin or
metronidazole
and
clarithromycin;

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