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    Antiarrhytmics Treatable Antiarrhytmics: Atrial Fibrillation, Atrial Flutter, Vtach and PSVT Drugs MOA Indication S/E Notes

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    monica lee
    This document summarizes different classes of antiarrhythmic drugs used to treat atrial fibrillation, atrial flutter, ventricular tachycardia, and paroxysmal supraventricular tachycardia. It lists the mechanism of action, indications, side effects, and notes for each drug class, including Class Ia-c sodium channel blockers, Class II beta blockers, Class III potassium channel blockers, and Class IV calcium channel blockers.

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    Antiarrhytmics Treatable Antiarrhytmics: Atrial Fibrillation, Atrial Flutter, Vtach and PSVT Drugs MOA Indication S/E Notes

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    monica lee
    21 views1 page
    This document summarizes different classes of antiarrhythmic drugs used to treat atrial fibrillation, atrial flutter, ventricular tachycardia, and paroxysmal supraventricular tachycardia. It lists the mechanism of action, indications, side effects, and notes for each drug class, including Class Ia-c sodium channel blockers, Class II beta blockers, Class III potassium channel blockers, and Class IV calcium channel blockers.

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    Anti Ar Rhytm Ics

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    This document summarizes different classes of antiarrhythmic drugs used to treat atrial fibrillation, atrial flutter, ventricular tachycardia, and paroxysmal supraventricular tachycardia. It lists the mechanism of action, indications, side effects, and notes for each drug class, including Class Ia-c sodium channel blockers, Class II beta blockers, Class III potassium channel blockers, and Class IV calcium channel blockers.

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    21 views1 page

    Antiarrhytmics Treatable Antiarrhytmics: Atrial Fibrillation, Atrial Flutter, Vtach and PSVT Drugs MOA Indication S/E Notes

    Uploaded by

    monica lee
    This document summarizes different classes of antiarrhythmic drugs used to treat atrial fibrillation, atrial flutter, ventricular tachycardia, and paroxysmal supraventricular tachycardia. It lists the mechanism of action, indications, side effects, and notes for each drug class, including Class Ia-c sodium channel blockers, Class II beta blockers, Class III potassium channel blockers, and Class IV calcium channel blockers.

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    Antiarrhytmics

    Treatable antiarrhytmics: Atrial fibrillation, Atrial Flutter, Vtach and PSVT

    Drugs MOA Indication S/E Notes


    Class Ia Fast sodium channel Afib Risk for torsades de Disopyrmaide,
    blockers that affect A flutter pointe Quinidine,
    phase 0 (depolarization) PSVT Pocainamide
    Vtach Procainamide- lupus like
    Slows conduction syndrome “Double Quarter
    velocity Pounder”
    Quinidine- cinchonism
    Prolongs action potential (headaches, tinnitus,
    duration altered mental status)
    Prolongs refractory
    period (QT interval)

    Class Ib Fast sodium channel Helps stabilize Local anesthetic toxicity Lidocaine,
    blockers that affect VTach in situations (CNS symptoms: Mexiletine,
    phase 0 (depolarization) where heart is confusion, seizure) Tocainide
    diseased or
    Shorten action potential ischemic
    duration but “Lettuce, Mayo,
    preferentially binds to Tomato”
    ischemic or abnormal
    cells
    Class Ic Fast sodium channel Supraventricular Contraindicated in Encainide,
    blockers that affect tachycardia patients with heart Moracizine,
    phase 0 (depolarization) disease dues to Flecainide,
    proarrhytmic effect in Propafenone
    Do not change action these patients
    potential duration but “Eat More Fries
    bids to Na channels most Please”
    avidly, especially AV node
    Class II Beta blockers; beta PSVT Heart block
    adrenergic antagonists Afib Impotence
    Aflutter Bradycardia
    Stop sympathetic activity Bronchospasm
    on the heart sedation

    Decrease HR and AV
    nodal conduction velocity
    (increased PR interval on
    ECG)
    Class III Potassium channel Torsades de pointes Amiodarone (Class I
    blockers that affect to IV activity),
    phase 3 (repolarization) Amiodarone: Bretylium,
    Photosensitivity Dofetilide, Ibutilide,
    Prolongs action potential Pulmonary fibrosis Sotalol (beta
    Prolongs refractory (check PFTs) blocker but is Class
    period Thyroid function (iodine III)
    in drug causes thyroid
    abnormalities) and “A Big Dog Is Scary”
    hepatotoxicity (check
    LFTs)

    Class IV L-type Calcium Channel PVST Edema Verapamil,


    Blockers Heart block diltiazem
    Constipation
    Decrease conduction Flushing
    velocity and heart rate

    Decrease rapidity of SA
    node depolarization

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