Abscess
Abscess
Abscess
Sometimes an abscess opens itself and drains on the skin surface but often it needs incision and
drainage.
Anatomy of skin:
The skin is the largest organ of the body; it performs lot of functions that includes:
• Protects us from microbes and the elements.
• Helps in regulating body temperature.
• Permits the sensations of touch, heat, and cold.
Pathophysiology of an abscess:
Abscess is a series of immune reactions. Abscess develops in the damaged tissue when our body’s
immune system protects body against entrance of foreign substance and prevents spread of harmful
micro-organisms.
During an infection by bacteria a large number of white blood cells especially neutrophils migrates to
the infected wound. This mechanism occurs as a result of getting signals from cytokines. The cytokines
are responsible to alert the neutrophils to injury and cell death.
The infected site is then filled with pus, i.e. collection of dead cells and chemical mediators of immune
reaction. The infected site is separated from the surrounding healthy tissue by an abscess wall….
Classification of Abscess
• Cystic acne: Cystic acne occurs in deeper skin tissue. Its occurence is most common on the face and in
the teenage years.
• Pilonidal cyst: It develops in the crease of the buttocks. Pilonidal cysts begin as tiny areas of infection
in the skin from which hair grows.
• Perianal abscess (Anorectal abscess): it is an infection of the soft tissues that surrounds the anal canal,
discrete abscess cavity forms, bacteria common in the digestive system, such as E.coli are responsible
for causing rectal abscess.
• Lung abscess: it is the necrosis of pulmonary parenchyma that is caused by microbial infection, that is
of two types-
Mortality of Abscess
Abscess usually do not cause any serious complications. But it can cause a life-threatening condition if it
is formed in any internal organ.
Age/sex prevalence of abscess
Causes of abscess
The major cause of formation of abscess is obstruction of sweat glands or sebaceous (oil) glands of skin,
inflammation of hair follicles or minor breaks and punctures of the skin.
Infectious agents or germs get into these glands through dirty skin and then body gives response to
these germs in the form of inflammation as a body defenses to kill these germs.
The center part of abscess liquefies and contains dead cells, bacteria and other waste. Then this area
begins to grow and hence lead to pain under the skin and along with it inflammation of areas of skin
adjoining the eruption.
Individuals with weak immune system are prone to get certain abscess more often. Diseases weakening
the immune system of body are as follows
•Leukemia
•Diabetes
•Cancer
•AIDS
•Peripheral vascular disorders
•Crohn’s disease
•Ulcerative colitis
•Severe burns
•Sickle cell disease
•Chronic steroid therapy
•Chemotherapy
•Drug abuse
Mostly abscess is a painful mass within the skin that appears red, warm and tender to touch.
Some abscess come to a head and can rupture.
If cure is not given on time, abscess gets worse. Infection can spread to the tissues below it and even to
the blood.
When infection travels in blood it can lead to fever also.
Investigations of abscess
If there is fever along with abscess then following lab tests to be done
WBC
Platelets
ESR
TLC
DLC
X-ray chest are done to diagnose abscess in lungs.
Treatment of abscess
Prognosis of abscess