FECR4

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Faecal Egg Count Reduction Test Analysis

Instructions

This spreadsheet performs analysis of faecal egg count reduction tests.


It allows entry of test results from up to 20 sheep per group (control and
up to 6 test groups) and reports the %reduction in faecal egg output, as
well as whether anthelmintic resistance is present or not.

To use the spreadsheet, simply enter the data into the white data entry
areas on the Data sheet, then switch pages to the Calc or Results sheets
to view the the results.

Entering Data
1 Enter test results on the Data sheet. Results should be entered as
eggs per gram. If fewer than 20 animals have been tested in each
group, leave the remainder blank.

2 Enter the names of the drug or drug combinations being tested in


the top row of the data table.

3 If larval culture results are available, enter them into the lower area
of the Data sheet. These should be expressed in terms of the
percentage of larvae belonging to different species. The 'Larval
Count' data is included for records only.

Calculating Results
1
When data entry is complete, press F9 to perform the calculations.
Calculations and detailed results are shown on the Calc sheet.
2 Results for all species combined, as well as separate species
results are shown (if larval culture results have been entered). The
results shown include:

3 Results displayed include the mean FEC and variance, the percent
reduction in the mean count, and the variance of the reduction, as
well as the upper and lower 95% confidence limits. Where the
lower confidence limit is less than 0, this value is trunctated to 0.

4 A summary of results is shown on the Results sheet. This includes


a table of % reductions, as well as a table of drug effectiveness.
These tables may be saved or printed.

Printing Results
1 To print results, go to the Calc or Results sheet.

2 Click on the File menu and select Print (or else click on the Print
button). Press OK to start printing.

References and Acknowledgements


This spreadsheet was created by Angus Cameron, AusVet Animal
Health Services for the University of Sydney. It's calculations are
based on those of the 'Reso' FECRT analysis program (Version 2.0
Revised 17-07-90 ) by Leo Wursthorn and Paul Martin of CSIRO,
Animal Health Research Laboratory, PARKVILLE, 3052. The
calculations are based on those published in 'Anthelmintic
Resistance': Report of the Working Party for the Animal Health
Committee of the SCA. CSIRO, 1989.
Test Results Data Entry Sheet
Drench Name
Animal ID Pre-Test Control Levamisole Benzimidazole Ivermectin Drench 4
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Larval Culture Data Entry Sheet

Control Levamisole Benzimidazole Ivermectin Drench 4


Larval count
Sp. Ostertagia:
Sp. Trichostrongylus:
Sp. Haemonchus:
Sp. Other:

Calculations
Sp. Ostertagia:
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Sp. Trichostrongylus:
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Sp. Haemonchus:
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Sp. Other:
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me
Drench 5 Drench 6

Drench 5 Drench 6
Detailed Calculations and Results
Combined Species
Drench Pre-Test Control Levamisole Benzimidazole Ivermectin Drench 4 Drench 5 Drench 6
Number 0 0 0 0 0 0 0 0
Arith. Mean
Var (FEC)
% Reduction
Var (Reduction)
Upper 95% CL
Lower 95% CL

Drench effectiveness

Sp. Ostertagia:
Drench Control Levamisole Benzimidazole Ivermectin Drench 4 Drench 5 Drench 6
Number 0 0 0 0 0 0 0
% Total 0% 0% 0% 0% 0% 0% 0%
Arith. Mean
Var (FEC)
% Reduction
Var (Reduction)
Upper 95% CL
Lower 95% CL

Drench effectiveness
Sp. Trichostrongylus:
Drench Control Levamisole Benzimidazole Ivermectin Drench 4 Drench 5 Drench 6
Number 0 0 0 0 0 0 0
% Total 0% 0% 0% 0% 0% 0% 0%
Arith. Mean
Var (FEC)
% Reduction
Var (Reduction)
Upper 95% CL
Lower 95% CL

Drench effectiveness

Sp. Haemonchus:
Drench Control Levamisole Benzimidazole Ivermectin Drench 4 Drench 5 Drench 6
Number 0 0 0 0 0 0 0
% Total 0% 0% 0% 0% 0% 0% 0%
Arith. Mean
Var (FEC)
% Reduction
Var (Reduction)
Upper 95% CL
Lower 95% CL

Drench effectiveness
Sp other:
Drench Control Levamisole Benzimidazole Ivermectin Drench 4 Drench 5 Drench 6
Number 0 0 0 0 0 0 0
% Total 0% 0% 0% 0% 0% 0% 0%
Arith. Mean
Var (FEC)
% Reduction
Var (Reduction)
Upper 95% CL
Lower 95% CL

Drench effectiveness
Summary Results
Percent Faecal Egg Count Reduction
Drench Levamisole Benzimidazole Ivermectin Drench 4 Drench 5 Drench 6
All species
Sp. Ostertagia:
Sp. Trichostrongylus:
Sp. Haemonchus:
Sp. Other:

Drench Effectiveness
Drench Levamisole Benzimidazole Ivermectin Drench 4 Drench 5 Drench 6
All species
Sp. Ostertagia:
Sp. Trichostrongylus:
Sp. Haemonchus:
Sp. Other:

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