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CHEMVIBES
C H E N G A L P A T T U M E D I C A L C O L L E G E
F r o m t h e e d i t o r i a l b o a r d . . .
Hi friends !
A new avatar– when we sat down to create the issue you’re holding
in your hands, the only thought in our minds was to redesign the news-
letter which you would enjoy reading .
In this first issue of 2010 we have highlighted the top 10 medical inno-
vations of last year. We have increased the content of medical articles
– articles which we hope are worth your time spent reading.
Medical Myth Buster, Health tip, and for the fun part, Medtoon,
are some of the sections we have added to the classical issue– we
plan to add more in future.
P.SUBRAMANI M.SOWMYA
MAGAZINE SECRETARY JT.MAGAZINE SECRETARY
1
MAGAZINE ASSOCIATION
EX.OFFICIO PRESIDENT
DR.P.PARASAKTHI, M.D.,
VICE PRINCIPAL
TREASURER
DR.RAVI, M.D.,
DEPT. OF PATHOLOGY
STAFF ADVISORS
EDITORS
P.SUBRAMANI
M.SOWMYA
2
INSIDE THIS ISSUE
PEGylated DENDRIMERS 27
MEDNEWS 38
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STORY HIGHLIGHTS
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3) Scientists have developed a new kind of hearing aid
that does not encumber patients with the usual problems
such as low batteries, having to remove the device before
showering or sleeping and over amplified noises. "The Lyric", made
by U.S. company Insound Medical, avoids the possible dangers of
surgery by being hidden deep inside the ear canal, one sixth of an
inch from ear drum. The device is worn 24 hours a day and need to
be replaced 3-4 times per year.
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7) Your wallpaint could protect you from dangerous bacte-
ria, according to scientists at the University of South Da-
kota. They have invented a germ-killing molecule that can
be added to paint and cloth to give it antimicrobial properties. The
bleach like substance is called N-halamine cl-TMPM.
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The stress hormone cortisol shrinks the brain's
memory centers and can hamper one's ability to
learn and recall. Cutting stress is an important first
step to preserving memory.
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PEGylated Dendrimers : A Novel
Mechanism of Drug Delivery
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*New blood biomarker to predict
cancer spread
Recent research came up with a new blood
biomarker that has a high accuracy of predicting the spread of
prostate cancer to other parts of the body through the lymph
nodes. Such spreading of cancer cells are usually not detected
by conventional imaging methods like CT scans. This new blood
test measures the level of endoglin, a plasma biomarker which
was also studied to predict the spread of colon and breast can-
cer.The levels of endoglin in the blood were associated with in-
creased risk of cancer cells spreading to the lymph nodes. Each
1ng/mL increase of plasma endoglin increases the risk of cancer
spread by 17 percent.
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plain noise by upping the volume on speech while reducing
background sound. The screeching feedback problems have
also been reduced digitally with feedback cancellation.
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*Filtering the Blood of Infectious Bacteria/
Viruses
Called the HemoPurifier, it is a machine similar to a dialy-
sis machine that uses filters to take out viruses and bacteria
from the blood, which can be used for extreme cases of infec-
tion. The filter consists of tiny fibers that have active filter-
ing abilities, attracting specific bugs (viruses and bacteria) to
lessen their numbers to a manageable level that is controllable
through regular drug treatment. The device works by drawing
blood from an artery, then filtering it through the mesh of fi-
bers that attracts the bugs that are to be removed thus ex-
tending the life of people who have severe infections.
The key is the filters that are treated with specific agents
that are able to attract specific bugs, one filter for the AIDS
virus, another for Flu and so on and so forth. The whole blood
volume circulates through the filter once every eight minutes
and full treatment can take as little as a month with each round
taking an hour or so to complete. This breakthrough can allow
better treatment of such deadly diseases such as Ebola and
other highly contagious bugs that are currently killing more
people each and every year●
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MEDICAL MYTH BUSTER
The theory for using only 10% of our brainpower is there for
almost a century. Sometimes this belief is charged to Albert
Einstein but this has not been recorded to any report or
statement. It is believed that they reason for carrying out
this myth for so many years is to stress people the importance
of self-improvement.
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ALTERNATIVE TO OPEN HEART
SURGERY
Interventional Cardiologists Help
The Faint Of Heart Without Surgery...
Surgery...
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brain while he attempted to speak.
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Genetic screening techniques that allow
parents to choose their children's gender
are now more accurate than ever and are
becoming increasingly mainstream, but
experts are divided over whether the
technology should be used in this way.
But PGD also can also be used to allow people undergoing in-
vitro fertilization to select the gender of the embryo im-
planted in the mother's uterus.
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Using PGD for gender selection is banned in most countries,
but it is legal in the U.S., where the procedure costs around
$18,000, including in-vitro fertilization.
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S
U
Anything that boosts your
R stress level can make you more
P vulnerable to tension head-
R aches or migraines.
I
S
I
N
G —Tension headaches are thought to be caused by a height-
ened sensitivity of nerve pathways in the brain that relay
pain.
H
E — Migraines come from changes within the brain itself. Dur-
@ ing a migraine, brain signals trigger the release of chemicals
that alter blood vessel dilation. These signals also activate
D inflammation in the brain, which can lead to a migraine
@ headache.
C
H *Warm Weather
When the temperature climbs, so does the likelihood of de-
E veloping a migraine or other severe headache. In one recent
study, researchers found a 7.5% increase in headache risk
T for every 9 degrees Fahrenheit. Low barometric pressure,
which often precedes rain, was linked to a small bump in
R non-migraine headaches.
I
G *Strong Scents
G Strong smells -- even nice ones -- trigger migraines in many
E people. Why this happens is unclear, but the odors may
R stimulate the nervous system. The most common culprits
are paint, dust, perfume, and certain types of flowers.
S
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*Hair Accessories
How you wear your hair can take a toll on your head. A tight pony-
tail may strain the connective tissue in the scalp, leading to a
hairdo headache. Headbands, braids, and tight-fitting hats can cre-
ate the same effect. If this is the cause of your headache, letting
your hair down usually brings fast relief.
Physical exertion causes blood vessels in the head, neck, and
scalp to swell, producing a build-up in pressure. Examples include
jogger’s headache
*Poor Posture
You don’t have to work up a sweat to build pressure in the head
and neck muscles. Slouching at your desk will do the job, too.
Common forms of poor posture include hunching your shoulders,
using a chair with no lower-back support, staring at a monitor that
is too low or too high, and cradling a phone between your ear and
shoulder. If you have frequent tension headaches, take a good
look at your workspace.
*Cheese
One of the most common migraine triggers is aged cheese, includ-
ing blue cheese, brie, cheddar, feta, mozzarella, parmesan, and
Swiss. The culprit is a substance called tyramine, which forms
when certain types of protein break down. The longer a food ages,
the more tyramine it contains.
*Skipping Meals
Hunger headaches aren’t always obvious. If you skip a meal, your
head could start to ache before you realize you’re hungry. The
trouble is a dip in blood sugar. But don’t try to cure a hunger head-
ache with a candy bar. Sweets cause blood sugar to spike and
then drop even lower.
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*Smoking
Smoking is known to trigger headaches -- and not just in the per-
son holding the cigarette. Secondhand smoke contains nicotine,
which causes blood vessels in the brain to narrow. Giving up ciga-
rettes or reducing exposure to secondhand smoke appears espe-
cially helpful to patients with cluster headaches. These are ex-
tremely painful one-sided headaches that occur in groups.
*Caffeine
For the headache-prone, caffeine fits firmly into the category of
“can’t live with it, can’t live without it.” In moderation, caffeine is of-
ten beneficial -- in fact, it’s found in many headache medications.
But chain-chugging coffee can be a cause of headaches. And, if
you’re hooked on caffeine, cutting back abruptly may only make
things worse. Caffeine withdrawal is another headache trigger
—— Anushri. S, CHMC
Celestians ‘06
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Hello doc...
An elderly man has just moved to a new town, when he is
taken ill and decides that he needs to see a doctor.
The man thinks about this and looks nervous. He asks the man
if the doctor's fees are expensive.
The man looks even more worried now and exclaims in amaze-
ment, "A thousand dollars?!"
The man replies, "Yes, but all your visits after that for the
rest of your life are free!"
The man thinks about this, and then gets called by the nurse
to go in to see the doctor.
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Making Cells Feel Right At Home
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Scientists have an emerging interest in lectins, naturally occur-
ring chemicals in plants, because of their ability to halt the
chain of reaction that leads to a variety of infections. Some of
the most promising compounds for inhibiting vaginal and rectal
HIV transmission are agents that block the virus prior to inte-
gration into its target cell.
The problem with some HIV drugs is that the virus can mutate
and become resistant, but that's much harder to do in the
presence of lectins. Lectins can bind to the sugars found on
different spots of the HIV-1 envelope, and presumably it will
take multiple mutations for the virus to get around them●
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More continuous exposure to bites will maintain high levels of
protective immunity, through natural boosting, for a life time.
So the insect shifts from being a pest to being beneficial, ac-
cording to the research.
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Let us take this example (which we have adapted from a fa-
mous television series) of a 29 year old woman who was a school
teacher and had her first seizure one month ago during which
she became dysarthric followed by tonic-clonic motor activity.
Protein markers for the 3 most prevalent brain cancers were
negative. The patient's symptoms did not respond to radiation.
There was no past medical history, she was not on any medica-
tions, there were no known allergies.
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However, the fact that none of the schoolchildren were ill
meant that this was likely not the cause of the patient's symp-
toms. The following day, the patient experienced temporary
blindness
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THINK TANK
Here are a few questions to set your grey cells on fire!
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WILL U FAVOUR THE TECHNOLOGY TO
CHOOSE YOUR CHILD’S GENDER ??
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An elderly man has just moved to a new town, when he is taken ill and
decides that he needs to see a doctor.
In the doctor's waiting room, he tries to find out a bit about the doctor.
He asks the man sitting next to him if the doctor is a specialist.
The man thinks about this and looks nervous. He asks the man if the
doctor's fees are expensive.
The man says: "Well, he is and he isn't. You see, he charges you one
thousand dollars for your first visit."
The man looks even more worried now and exclaims in amazement, "A
thousand dollars?"
The man replies, "Yes, but all your visits after that for the rest of your life
are free!"
The man thinks about this, and then gets called by the nurse to go in to
see the doctor.
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