Suppository QQ

Choose the most appropriate answer.
1. In case of unconscious patient, the preferred dosage form is:

a) Oral tablet
b) Soft gelatin capsule
c) Rectal suppository
d) Ointment
2. Bougies are
a) Compressed into conical shapes
b) Intended for both sexes
c) Prepared with PEG
3. All of the following about aurnaria are correct except

a) Ear cones
b) Very rarely used
c) Prepared from glycero gelatin base only
d) Prepared in urethral suppository molds
4. The absorption of salicylic a from rectal supp can be increased at PH

a) 4
b) 7
c) 9
d) a &b
5. For drugs administered high in the rectum, the following statements are true except:
a) Drugs drained by superior hemorrhoid vein
b) They are carried by rectal veins directly to liver
c) They are not subjected to metabolism
d) Their uptake is influenced by the rectal PH 6.8
6. Hepatic 1st pass effect of drugs could be reduced by rectal administration as:
a) Superior hemorrhoid vein joins directly to inferior vena cava
b) Inferior and middle hemorrhoid veins join to mesenteric vein
c) Both of the above
d) Non of the above
1
7. The rate limiting step in drug absorption from suppository is
a) the release of the drug from the base
b) the dissolution rate of the drug in body fluids
c) neither a nor b
8. The rate of drug diffusion to the site of rectal absorption depends on all of the
following except
a) Nature of medicament
b) Chemical nature of solids present
c) PH of rectal fluids
9. An ideal suppository base should have

a) Acid value >2
b) Iodine value < 7
c) Low water number
d) All of the above
10. All the following about the disadvantages of the theobroma oil are correct except
a) Rancidity
b) High reactivity
c) Adherence to mold
d) Too low softening point
11.The Beta stable form of cacao butter melts at

a) 15 C
b) 20 C
c) 28 C
d) Non of these
12.All of the following about Witepsol H15 are correct except:

a) Contains glyceryl mono stearate.
b) Alternative base to cacao butter
c) Melts at 32-34 C
d) Doesn't contract sufficiently.
2
13.Glyceryl mono stearate:
a) W/O emulsifier
b) O/W emulsifier
c) Increase water number
d) a & c
e) b & c
14.Hexane-1,2,6- triol is a
a) Viscosity modifier
b) Preservative
c) Plasticizer
d) Thickening agent.
15.Macrogol suppository can be prepared by:

a) Molding
b) Cold compression
c) Hand rolling
d) a & b
16.All the following about PEG base containing 96% PEG 1000 & 4% PEG 400 are true
except
a) Rapid disintegration
b) Need refrigeration
c) Used for water-soluble, PEG-insoluble drugs
17.The following bases are recommended for preparing pessaries except

a) Carbowax
b) Glycerogelatin
c) Cacao butter
18.Which of the following bases is rarely used for preparing medicated rectal
suppository
a) PEG
b) Cacao butter
3
c) Wecobee
d) Glycero gelatin
19.All the following can be added to cope hot weather except

a) Bees wax
b) Additional gelatin
c) Wool fat
d) High M.wt PEG
20.Macrogol bases are incompatible with

a) Salicylic acid
b) Aspirin
c) Quaternary ammonium compound
d) All the above
21.Nonoxyneol-9
a) Restores vaginal mucosa to its normal state
b) Used for vaginal infection
c) Is spermicidal
d) a , b & c
22.all the following about bioadhesive vaginal tablets are correct except
a) used for topical & systemic effect
b) hydrate after insertion
c) require more frequent dosing
d) Reduce the rate of drug release.
23.A suppository is generally intended for use in

(a) Rectum (b) Vagina (c) Urethra (d) All the above
24.Vaginal suppositories also called as

(a) Pessaries (b) Simple suppositories (c) Bougies (d) None
25.Weight of rectal suppository for adults is

(a) 1 g (b) 2 g (c) 5 g (d) None
26.Weight of rectal suppository for children is
4
(a) 1 g (b) 2 g (c) 5 g (d) None
27.Urethral suppositories also called as

(a) Pessaries (b) Bougies (c) Both (d) None
28.Urethral suppositories having which shape

(a) Oviform shape (b) Torpedo shape (c) Pencil shape (d) None
29.Weight of urethral suppository for males & females respectively

(a) 4 & 2 (b) 2 & 4 (c) 4 & 6 (d) 6 & 4
30.Shape of vaginal suppositories is

(a) Oviform shape (b) Torpedo shape (c) Pencil shape (d) None
31.Rectal suppositories mainly used for the treatment of

(a) Constipation (b) Hemorrhoids (c) Both (d) None
32.The number of milligrams of KOH required neutralizing free acids & saponify the
esters contained in 1 g of fat is known as
(a) Iodine value (b) Saponification value (c) Water number (d) Acid value
33.The number of grams of iodine that reacts with 100 g of fat is known as
(a) Iodine value (b) Saponification value (c) Water number (d) Acid value
34.The number of milligrams of KOH required neutralizing free acids in 1 g of fat is

known as
( a) Iodine value (b) Saponification value (c) Hydroxil value (d) Acid value
35.Which of the following method is used to manufacture suppositories

(a) Hand molding (b) Compression molding (c) Pour molding (d) All the above
36.Cocoa butter available in following forms

(a) -form (b) -form (c) -form (d) All
37.The solidification point of cocoa butter lies between

(a) 12 13o (b) 20 30o (c) 5 10o (d) None
38.Which of the following method is simple & oldest method of preparation of

suppositories?
(a) Hand molding (b) Compression molding (c) Pour molding (d) All the above
5
39.Most commonly used method for producing suppositories on both a small & large
scale is
(a) Hand molding
(b) Compression molding (c) Pour molding (d) All the above
40.Rancidity generally results from

(a) Auto oxidation (b) Decomposition of unsaturated fats (c) Both
(d) None
41.Which of the following is not antioxidant?

(a) BHT (b) BHA (c) Tocopherol (d) Theobroma oil
42.Suppositories are generally evaluated by

(a) Melting range test (b) Breaking test (c) Liquefaction (d) All the above

Suppository QQ

Uploaded by

Copyright:

Available Formats

Suppository QQ

Uploaded by

Document Information

Original Description:

Original Title

Copyright

Available Formats

Share this document

Share or Embed Document

Sharing Options

Did you find this document useful?

Is this content inappropriate?

Copyright:

Available Formats

Suppository QQ

Uploaded by

Copyright:

Available Formats

Choose the most appropriate answer.

1. In case of unconscious patient, the preferred dosage form is:

3. All of the following about aurnaria are correct except

4. The absorption of salicylic a from rectal supp can be increased at PH

9. An ideal suppository base should have

11.The Beta stable form of cacao butter melts at

12.All of the following about Witepsol H15 are correct except:

15.Macrogol suppository can be prepared by:

17.The following bases are recommended for preparing pessaries except

19.All the following can be added to cope hot weather except

20.Macrogol bases are incompatible with

23.A suppository is generally intended for use in

24.Vaginal suppositories also called as

25.Weight of rectal suppository for adults is

26.Weight of rectal suppository for children is

27.Urethral suppositories also called as

28.Urethral suppositories having which shape

29.Weight of urethral suppository for males & females respectively

30.Shape of vaginal suppositories is

31.Rectal suppositories mainly used for the treatment of

34.The number of milligrams of KOH required neutralizing free acids in 1 g of fat is

35.Which of the following method is used to manufacture suppositories

36.Cocoa butter available in following forms

37.The solidification point of cocoa butter lies between

38.Which of the following method is simple & oldest method of preparation of

40.Rancidity generally results from

41.Which of the following is not antioxidant?

42.Suppositories are generally evaluated by

You might also like