Tzenalis Study Protocol
Tzenalis Study Protocol
Tzenalis Study Protocol
STUDY PROTOCOL
Abstract
Background: In the general population 3050% of adults will experience musculoskeletal neck pain in
any given year. The traditional pathoanatomical (biomedical) approach to the diagnosis of neck pain
disorders is widely acknowledged as inadequate. Psychosocial factors have been reported associated
with increased risk for more disabling chronic neck pain.
Objective: The objective of this article is to present the design of a qualitative study in combination
with a quantitative pretest posttest-control group design study. The aim of the described research is the
construction and performance of a new, valid tool in the form of questionnaire, in order health
professionals to administrate emotional reactions of patients suffering from chronic neck pain, the
effectiveness of which will be explored in conjunction with the implementation of a specific treatment
program and simultaneously, conducting advisory support.
Methods: A qualitative study using semi structured interviews will be conducted in 6 patients with
CNP. The results of the interviews will arise a reservoir of questions available for the new
questionnaire- tool for managing patients emotional reactions. Validity and reliability of the
questionnaire will be reassured checking conceptual validity, content validity and structural validity
with the use of exploratory factor analyses and confirmatory factor analyses.Then, 30 participants will
be separated in two groups: a) the control group where patients will follow the therapeutic exercise
program without parallel counseling, b) the experimental group where participants will follow along
therapeutic exercise program plus counseling.
Outcome measurement: Inclusion and exclusion variables, demographic variables, duration of neck
pain, specific complaint characteristics , smoking , the McGill Pain Questionnaire, the Neck Disability
Index , the Fear Avoidance Belief Questionnaire, the SF-36 Health Survey, the new questionnaire of
this study, neck goniometry measurements will be the standardized outcome measures.
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ripe content and close to the subject. The development of the research (Burhard &
researcher can, simultaneously, observe Morrison, 199). The analyses of the
reactions, facial expressions, and body interviews made according to Table 1.
language, which are important for the
ANALYSES
THEMES
AN ALYSES STEPS
CATEGORIES CATEGORIES
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Meyer-Olkin measure of sampling adequacy To test the appropriate fit of the models
for checking the adequacy of the sample through confirmatory factor analysis the
(Kaizer, 1974). researchers will consider the following
indicators:
The method of factor analysis was chosen to
examine the construct validity of the a) x2 (chi-square), df (degrees of freedom),
instrument. The number of factors the ratio of x2 / df (x 2 / df ratio), Satorra-
determined according the analysis of the Bentler chi-square),
main components in oblique and varimax b) the Comparative Fit Index, CFI,
rotation axes. The exploratory factor analysis c) the Incremental Fit Index, IFI,
determines the exact number of factors that
will be drawn from the analysis (Kline, d) the Adjusted Goodness of Index, AGFI,
1994). Both the varimax rotation and the e) the Standardized Root Mean Squared
oblique rotation (delta = 0) of the axes will Residual, SRMR, and
determine the interrelationships of factors f) the Root Mean Squared Error of
and the degree of their association (Browne, Approximation, RMSEA (Bentler & Chou,
2001; Carmines & Zeller, 1979; Cudeck & 1987; Byrne, 1994; Bollen, 1989; Hoyle &
MacCallum, 2007; Fabrigar, Wegener, Panter, 1995; Hu & Bentler, 1999;
MacCallum, & Strahan, 1999; Thompson, Tabachnick & Fidell, 2006). Concurrent
2004; Widaman, 2007). validit and discriminant validity will also be
The following criteria will be used for examined.
selecting the number of factors: For internal consistency the researchers will
use the following indicators:
1) the screen plot test,
2) the eigenvalue-greater-than-one rule, a) the coefficient Cronbachs a,
3) the variance of each factor, b) the inter-item correlation,
4) the total variation from the exported c) the corrected item-total correlations
factors and
d) the Spearman-Brown coefficient and
5) the number of factors that can
conceptually be interpreted (Nunnally & e) the Guttman split-half coefficient
Bernstein, 1994; Tinsley & Tinsley, 1987; Procedure of questionnaire administration
Tabachnick & Fidell, 2006).
The questionnaire will be administered to
For internal consistency the researchers will
patients with CNP personally and
use the following indicators:
individually following by a cover letter. This
a) the coefficient Cronbachs a, letter will inform the participants about the
b) the inter-item correlation, university-department ID, the researchers
c) the corrected item-total correlations name, title, telephone number and e-mail. It
will also indicate the significance and the
d) the Spearman-Brown coefficient and purpose of the investigation, drawing the
e) the Guttman split-half coefficient. attention of participants during completion of
the questionnaire in order to collect valid and
Confirmatory factor analyses reliable information. The participants will
Before the main analysis of the questionnaire receive oral confirmation about the
with the method of confirmatory factor anonymity of responses and their ability to
analysis in 300 patients, the researchers will be informed about the results of the survey.
test the distribution of the variables with the The duration of completion the questionnaire
following indicators: is estimated at about ten (10) minutes. The
researcher will be present during the process
a) univariate skewness), in order to resolve any questions and to give
b) the univariate kyrtosis and all necessary clarifications and instructions.
c) the Mardia coefficient-relative Patients will complete the questionnaire in
multivariate kurtosis (Mardia, 1970). their treatment place.
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2nd stage of the research: The real applied on the neck for all patients in order
experiment to reduce the pain sensation. All patients will
follow a program in collaboration with
Study design
experienced physiotherapist with:
This research method is a pretest posttest-
control group design. This type of study is a) stretching exercises for the neck muscles,
designed to investigate how really effective the shoulder and the upper limbs,
is an additional intervention in daily practice. b) strength training of the flexor and extensor
It also provides answers for the overall neck muscles from different positions,
patients benefits, suggesting evidence that
will help healthcare professionals to make c) proprioception exercises,
the right choices among appropriate d) dynamic exercises of the shoulder and
interventions (Stevens, 2001; McCarney et upper limbs with weights sets and elastic
al., 2002; McPherson , 2004). resistance bands,
Sampling e) exercises to improve the kinesthetic
The sample size of this experiment will be 30 ability, f) technique of progressive relaxation
patients with CNP. The researchers will use and diaphragmatic breathing exercises
the stratified random sampling from a combined with inhalation-exhalation.
patients list that will fulfill the inclusion All patients will come for treatment 2-3
criteria. Participants will be separated in two times per week until the completion of 12
groups: sessions (about for 4-6 weeks). The duration
a) the control group where patients will of each session for all groups will be
follow the therapeutic exercise program approximately 45 minutes.
without parallel counseling, b) the Outcome measurements
experimental group where participants will
follow along therapeutic exercise program In every intervention is necessary the
plus counseling program which will result determination and evaluation of the results
from the completion of the questionnaire. and their comparison with the intended or
The process will take place in the university projected results. Standardized outcome
departments laboratory (Physical Education measures provide a common language with
and Sports Science at Democritus University which to evaluate the success of
of Thrace). interventions, thereby providing a basis for
comparing outcomes related to different
Therapeutic interventions intervention approaches (Table 2).
Hot compresses ten minutes before and ten
minutes after the therapeutic program will be
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