Biomentors (MCDB 1B) - Immunology Quiz (ANSWERS)

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Immunology Quiz

1. Which one of the following statements is incorrect?


a. If a TC cell binds to the MHC I antigen complex, the TC cell is activated to proliferate
and differentiate.
b. If a cell has been infected by a virus it may present protein fragments that are not
normally found in the body.
c. When an antigen is phagocytosed by a "professional" antigen-presenting cell, it is broken
down and fragments are presented at the cell surface by class II MHC proteins.
d. In most body cells, foreign protein fragments are bound by class I MHC molecules and
displayed on the plasma membrane, where TC cells can check them.
e. A foreign peptide displayed by a class II MHC protein is a signal to kill the cell that
is displaying it.

2. Which of the following cells release histamine upon damage?


a. Plasma cells
b. Monocytes
c. Cytotoxic T-cells
d. Macrophages
e. Mast cells

3. Which one of the following is a characteristic feature of the adaptive immune system?
a. Response is non-specific
b. Exposure leads to immediate maximal response
c. Lag time between exposure and maximal response
d. It is independent of antibodies
e. No immunological memory

4. Which of the following statements is CORRECT?


a. MHCII presents antigens from extracellular pathogens and interacts with CD8.
b. MHCI presents antigens from extracellular pathogens and interacts with CD4.
c. MHCI presents antigens from intracellular pathogens and interacts with CD8.
d. MHCII presents antigens from intracellular pathogens and interacts with CD4.
e. MHCI presents antigens from intracellular pathogens and interacts with CD4

5. Which of the following did NOT arise from a myeloid progenitor cell?
a. Basophil
b. Mast cells
c. Erythrocyte
d. Macrophage
e. Natural killer cell
6. Which of the following is FALSE?
a. Specific defense mechanisms are typically the bodys first line of defense.
b. Autoimmune diseases are the result of an overactive immune response.
c. Defense systems involve recognition of self from nonself.
d. Nonspecific defenses typically act more rapidly than specific defenses.
e. The skin is an example of a nonspecific defense.

7. Which one of the following cell types can function as an antigen-presenting cell for a
helper T cell?
a. dendritic cells
b. macrophages
c. B cells
d. A and C
e. A, B, and C.

8. The production of antibodies that bind to antigens is most accurately referred to as:
a. nonspecific immunity.
b. cell-mediated immunity .
c. autoimmunity.
d. humoral immunity.
e. cytotoxic immunity

9. The polypeptide chains in an immunoglobulin molecule are held together primarily with:
a. ionic interactions
b. hydrogen bonding
c. disulfide bonds
d. hydrophobic interactions
e. glycosidic linkages

10. Which one of the following cell types would be least likely to induce activation of a
cytotoxic T cell?
a. Liver cells
b. Tracheal epithelial cells
c. Red blood cells
d. Skeletal muscle cells
e. Pancreatic cells

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