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7Kh0Rqrdplqh+/Srwkhvlviruwkh 3Dwkrsk/Vlrorj/Ri3Dudsklolf'Lvrughuv $Q8Sgdwh

This document summarizes an updated monamine hypothesis for the pathophysiology of paraphilic disorders proposed by Martin P. Kafkas in 1997. The hypothesis is based on evidence that monoamine neurotransmitters like dopamine, norepinephrine, and serotonin play a regulatory role in human and animal sexual motivation and behavior. Studies have shown that drugs affecting these neurotransmitters can significantly impact sexual behavior and arousal. Additionally, paraphilic disorders appear to have Axis I comorbidities associated with monoamine dysregulation like antisocial behavior, anxiety, depression, and hypersexuality. Recent data supporting or refuting this monoamine hypothesis is reviewed.

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0% found this document useful (0 votes)
52 views9 pages

7Kh0Rqrdplqh+/Srwkhvlviruwkh 3Dwkrsk/Vlrorj/Ri3Dudsklolf'Lvrughuv $Q8Sgdwh

This document summarizes an updated monamine hypothesis for the pathophysiology of paraphilic disorders proposed by Martin P. Kafkas in 1997. The hypothesis is based on evidence that monoamine neurotransmitters like dopamine, norepinephrine, and serotonin play a regulatory role in human and animal sexual motivation and behavior. Studies have shown that drugs affecting these neurotransmitters can significantly impact sexual behavior and arousal. Additionally, paraphilic disorders appear to have Axis I comorbidities associated with monoamine dysregulation like antisocial behavior, anxiety, depression, and hypersexuality. Recent data supporting or refuting this monoamine hypothesis is reviewed.

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shendy
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© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
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