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Structure and Function of Body Systems 12/05/2015

Muscular System

Macrostructure and Microstructure


Proximal closer to the trunk
Distal farther from the trunk
Superior closer to the head
Inferior closer to the feet
Origin of a muscle - defined by its proximal attachment
Insertion of a muscle - defined by its distal attachment
Muscle Breakdown (Components)
Tendon Muscle Belly Perimysium Fasciculus Endomysium
Sarcolemma Sarcoplasm Myofibril Myofilaments
Actin(thin) and Myosin(thick)
Perimysium connective tissue surrounding the muscle fiber
bundles
Fasciculus a group of muscle fibers
Endomysium connective tissue surrounding each muscle fiber
Sarcolemma membrane between muscle fiber and endomysium
Sarcoplasm the cytoplasm of the muscle fiber
Myofibril contain the apparatus that contracts the muscle cells
Myofilaments
o Sliding-Filament Theory of Muscular Contraction
States that the Actin at each end of the sarcomere slide
inward on myosin filaments, pulling the Z-lines toward
the center of the sarcomere and thus shortening the
muscle fiber
H-zone and I-band shrink when the actin
filaments slide over the myosin
Resting Phase
Little calcium is present so cross bridges are not
bound to Actin
Excitation-Contraction Coupling Phase
Release of calcium ions binds to troponin and
causes a shift in tropomyosin
Myosin cross bridge attaches to actin allowing
flexion to occur
amount of force produced is directly related
to amount of cross bridges bound to actin
at that instant in time
Contraction Phase
Energy for CB flexion comes from breakdown of
ATP (adenosine triphosphate) to ADP (adenosine
diphosphate) from the catalyst enzyme ATPase
(myosin adenosine triphosphate)
***Calcium and ATP are necessary for
myosin cross-bridge cycling with actin
filaments***
Recharge Phase
This occurs as long as calcium is available in the
myofibril and ATP to separate the myosin and
actin
Relaxation Phase
When stimulation of the motor nerve stops and
myosin and actin filaments are in their unbound
state
o Actin(thin) two strands in a double helix
o Myosin(thick)
Cross bridges - parts of myosin that protrude away
from the body of the fiber
Pull on the Actin to contract muscle
o A-Band - alignment of myosin fibers
o I-band alignment of actin fibers
o Z-line middle of the i-band
o H-zone center of sarcomere where only myosin fibers exist

Neuromuscular System

Activation of Muscles
When a motor neuron fires an impulse, all of the fibers that it
serves are simultaneously activate and develop force
*Less muscle fibers = more precise movements*
All or None Principle every fiber that is touched by a neuron is
activated, a stronger impulse cannot produce a stronger contraction
o Like firing a gun
Once a significant amount of pressure is applied to a
trigger, the gun fires squeezing the trigger harder
will not cause the bullet to go faster
Twitch the brief contraction of a muscle fiber
Tetanus when two twitches are delivered at such a high
frequency they begin to merge and eventually fuse
Muscle Fiber Types
Slow-twitch - force an relax slowly; long twitch develop time
o Type I
Usually fatigue resistant
High aerobic energy supply
Fast-twitch develop force and relax quickly; short twitch time
o
fatigable with low aerobic power
rapid force development
o Type IIa
Greater capacity for aerobic metabolism
More capillaries
Greater resistance to fatigue than b
o Type IIb(x) -
Motor Neuron Recruitment
If motor neuron is recruited once, does not produce great force
If frequency is increased and twitches overlap, force increases
greatly
Different motor neurons called upon in different activities
o Jog slow twitch
o Power clean fast twitch
Preloading
Activation of muscle fibers before weighted resistance in range of
motion occurs
Proprioception
Proprioceptors - specialized sensory receptors located in joints,
muscles, and tendons
o Sensitive to pressure and tension
Relay muscle dynamic info to the conscious and
subconscious of CNS
o Muscle Spindles proprioceptors that consist several
modified muscle fibers enclosed in sheath of connective tissue
Provide info such as muscle length and rate of change
in length
Muscle lengthens = spindle stretched
Activates sensory neurons to spinal cord where it
connects with motor neurons
Spindles indicate degree of muscle activation to
overcome a resistance
o Golgi Tendon Organs proprioceptors located in tendons
attached end to end with muscle fibers
Activated when the tendon attached to active muscle is
stretched
tension increased = discharge of GTO increases
Cardiovascular System
Heart
o Right Side pumps blood through the lungs
o Left Side pumps blood through the rest of the body

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