International Chemical Safety Cards

ACETO I
C
NE S
CYANO C:
06
HYDRI 11
N

2-Hydroxy-2-methyl propionitrile
2-Methyl-lactonitrile
2-Cyanopropan-2-ol
p-Hydroxyisobutyronitrile
(CH3)2C(OH)CN / C4H7NO
Molecular mass: 85.1

ICSC # 0611
CAS # 75-86-5
RTECS # OD9275000
UN # 1541
EC # 608-004-00-X
March 23, 1998 Validated
TYPES OF
ACUTE HAZARDS/ FIRST AID/
HAZARD/ PREVENTION
SYMPTOMS FIRE FIGHTING
EXPOSURE
Combustible. Gives off NO open flames. Powder, AFFF, foam, carbon
FIRE irritating or toxic fumes (or dioxide.
gases) in a fire.
Above 74C explosive Above 74C use a closed In case of fire: cool drums,
vapour/air mixtures may be system, ventilation. etc., by spraying with water
EXPLOSION formed. but avoid contact of the
substance with water. Combat
fire from a sheltered position.

AVOID ALL CONTACT! IN ALL CASES CONSULT A

EXPOSURE DOCTOR!
Convulsions. Cough. Closed system and ventilation. Fresh air, rest. Half-upright
Dizziness. Headache. position. Artificial respiration
Laboured breathing. Nausea. may be needed. Refer for
INHALATION Shortness of breath. medical attention.
Unconsciousness. Vomiting.
Irregular heartbeat, tightness
in the chest.
MAY BE ABSORBED! Protective gloves. Protective Rinse and then wash skin with
SKIN Redness. Pain. (See clothing. water and soap. Refer for
Inhalation). medical attention.
EYES Redness. Pain. Face shield, or eye protection First rinse with plenty of water
in combination with breathing for several minutes (remove
protection. contact lenses if easily
possible), then take to a
 doctor.
Abdominal cramps. Burning Do not eat, drink, or smoke Rinse mouth. Refer for
sensation. Convulsions. during work. medical attention.
INGESTION
Unconsciousness. (See Notes,
(see Inhalation).
PACKAGING &
SPILLAGE DISPOSAL STORAGE
LABELLING
Sweep spilled substance into Provision to contain effluent from
Airtight. Do not transport with food
containers. Carefully collect fire extinguishing. Separated from
and feedstuffs.
remainder, then remove to safe strong bases, acids, water , food and
Marine pollutant.
place. Do NOT let this chemical feedstuffs . Well closed. Keep in a
T+ symbol
enter the environment. Personal well-ventilated room.
N symbol
protection: complete protective R: 26/27/28-50/53
clothing including self-contained S: 1/2-7/9-27-45-60-61
breathing apparatus. UN Hazard Class: 6.1
UN Packing Group: I
SEE IMPORTANT INFORMATION ON BACK
Prepared in the context of cooperation between the International Programme on Chemical Safety &
the Commission of the European Communities (C) IPCS CEC 1994. No modifications to the
ICSC: 0611 International version have been made except to add the OSHA PELs, NIOSH RELs and NIOSH IDLH
values.

International Chemical Safety Cards

ACETONE CYANOHYDRIN ICSC: 0611
PHYSICAL STATE; ROUTES OF EXPOSURE:
APPEARANCE: The substance can be absorbed into the
I COLOURLESS LIQUID , WITH body by inhalation, through the skin
CHARACTERISTIC ODOUR. and by ingestion.
M
PHYSICAL DANGERS: INHALATION RISK:
P The vapour is heavier than air. A harmful contamination of the air can
be reached rather quickly on
O CHEMICAL DANGERS: evaporation of this substance at 20C.
The substance decomposes rapidly on
R heating or on contact with bases or EFFECTS OF SHORT-TERM
water producing highly toxic and EXPOSURE:
T flammable hydrogen cyanide (see The substance is irritating to the eyes ,
ICSC 0492), and acetone (see ICSC the skin and the respiratory tract . The
A 0087). Reacts violently with acids andsubstance may cause effects on the
oxidants causing fire and explosion cardiovascular system and central
N hazard. nervous system , resulting in
asphyxia , cardiac disorders ,
T OCCUPATIONAL EXPOSURE convulsions , cyanosis and respiratory
LIMITS: failure . Exposure may result in death.
OSHA PEL: none Medical observation is indicated. See
D NIOSH REL: C 1 ppm (4 mg/m3) 15- Notes.
minute
A NIOSH IDLH: N.D. See: IDLH EFFECTS OF LONG-TERM OR
INDEX REPEATED EXPOSURE:
T TLV: (as CN) 5 mg/m (Ceiling value); The substance may have effects on the
(skin); (ACGIH 2004). central nervous system and thyroid ,
A resulting in impaired functions .

PHYSICAL Boiling point: 95C Vapour pressure, kPa at 20C: 3.0

PROPERTIES Melting point: -19C Relative vapour density (air = 1): 2.93
Relative density (water = 1): 0.93 Flash point: 74C c.c.
 Solubility in water: freely soluble, but Explosive limits, vol% in air: 2.2-12
decomposes in water
ENVIRONMENTAL The substance is very toxic to aquatic organisms. Avoid release to the
DATA environment in circumstances different to normal use.
NOTES
The occupational exposure limit value should not be exceeded during any part of the working exposure.
Specific treatment is necessary in case of poisoning with this substance; the appropriate means with instructions
must be available. Hazard and toxicity of this substance is due to its major metabolite - hydrogen cyanide (see
ICSC 0492). Card has been partly updated in October 2004 and 2005. See sections Occupational Exposure
Limits, EU classification, Emergency Response.
Transport Emergency Card: TEC (R)-61S1541

NFPA Code: H4; F1; R2

ADDITIONAL INFORMATION

ICSC: 0611 ACETONE CYANOHYDRIN

(C) IPCS, CEC, 1994

Neither NIOSH, the CEC or the IPCS nor any

person acting on behalf of NIOSH, the CEC or the
IPCS is responsible for the use which might be
made of this information. This card contains the
collective views of the IPCS Peer Review
Committee and may not reflect in all cases all the
IMPORTANT LEGAL NOTICE: detailed requirements included in national
legislation on the subject. The user should verify
compliance of the cards with the relevant legislation
in the country of use. The only modifications made
to produce the U.S. version is inclusion of the
OSHA PELs, NIOSH RELs and NIOSH IDLH
values.