Guaifenesin is an expectorant used to treat cough by promoting sputum secretion. It is rapidly absorbed and hydrolyzed in the GI tract, with an elimination half-life of 1 hour. Guaifenesin functions by reducing the surface tension of secretions, increasing productive coughing. Guaisin elixir contains 100mg of guaifenesin per 5mL dose and is administered orally to relieve cough according to age-based dosing guidelines. Potential side effects include gastrointestinal discomfort at high doses.
Guaifenesin is an expectorant used to treat cough by promoting sputum secretion. It is rapidly absorbed and hydrolyzed in the GI tract, with an elimination half-life of 1 hour. Guaifenesin functions by reducing the surface tension of secretions, increasing productive coughing. Guaisin elixir contains 100mg of guaifenesin per 5mL dose and is administered orally to relieve cough according to age-based dosing guidelines. Potential side effects include gastrointestinal discomfort at high doses.
Guaifenesin is an expectorant used to treat cough by promoting sputum secretion. It is rapidly absorbed and hydrolyzed in the GI tract, with an elimination half-life of 1 hour. Guaifenesin functions by reducing the surface tension of secretions, increasing productive coughing. Guaisin elixir contains 100mg of guaifenesin per 5mL dose and is administered orally to relieve cough according to age-based dosing guidelines. Potential side effects include gastrointestinal discomfort at high doses.
Guaifenesin is an expectorant used to treat cough by promoting sputum secretion. It is rapidly absorbed and hydrolyzed in the GI tract, with an elimination half-life of 1 hour. Guaifenesin functions by reducing the surface tension of secretions, increasing productive coughing. Guaisin elixir contains 100mg of guaifenesin per 5mL dose and is administered orally to relieve cough according to age-based dosing guidelines. Potential side effects include gastrointestinal discomfort at high doses.
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GUAIFENESIN
GUAISIN 60mL 100mg/5mL Elixir Oral Expectorant Description: Guaifenesin is an expectorant of the Propanediol derivatives. It has an IUPAC name of 3-(2-methoxyphenoxy) propane-1,2-diol and a chemical name of C10H14O4.
Guaisin is an elixir with clear, orange color and a sweet orange flavour. Formulation: 5mL of Guaisin elixir contains 100mg if the active ingredient Guaifenesin. Pharmacokinetics: Guaifenesin is rapidly absorbed in the GI tract. It is rapidly hydrolysed in which 60% in seven hours and excreted in the urine. It has a Half-life of approximately 1 hour. Pharmacodynamics: Guaifenesin is an expectorant and functions by increasing the output of phlegm/sputum and bronchial secretions by reducing the surface tension and adhesiveness. Ciliary action and a more productive and less frequent cough is exhibited with the increased flow of less viscous secretions. Indication: For the treatment of cough as an expectorant to relieve cough by promoting the secretion of sputum in the air passages. Recommended Dose: Age Recommended Dose Under 2 years
Consult a Physician.
2-6 yrs.
50-100 mg every 4 hours, not exceeding 600 mg in 24 hours. -1 teaspoon.
Children 6 to <12
100-200 mg every 4 hours, not exceeding 1200 mg in 24 hours. 1-2 teaspoons.
12 years and above
200-400 mg every 4 hours, not exceeding 2400mg in 24 hours. 2-4 teaspoons
Mode of Administration: Guaisin is administered orally.
Contraindications: Contraindicated to patients who are hypersensitive to Guaifenesin. Warning and Precautions: If symptoms persist, consult a physician. Drug Interactions: Guaifenesin has been shown to have interaction with 5-hydorxyindoleacetic acid (5HIAA) and vanilmandelic acid (VMA). Pregnancy and Lactation: Pregnancy Category: C Guaifenesin is only recommended for pregnant use if the benefit outweighs risks. Special precaution is recommended when administering Guaifenesin to lactating women. Adverse Effects: Reported adverse effect of the intake of Guaifenesin, in large doses include: Gastrointestinal discomfort, nausea and vomiting. Overdose: Nausea and vomiting may occur, discontinue medication and seek medical help immediately. Storage: Protect from light, heat and moisture. Store at a room temperature between 15 to 30 degrees Celsius. Dosage Forms: Guaifenesin products are available in liquids/syrups and Immediate or sustained release tablets. Caution: Manufactured by: CIAT Pharmaceuticals Note: [Place Address here] Market Authorization Holder: Note: [Name and Address here] Registration Number: Date of Revision: 1/06/17
