Scribd
Upload
246 views

Format and Content of An Example Case Report Abstract

This case report abstract summarizes the presentation of a 14-year-old girl with CLOVE syndrome who also presented with oral mucosal neuromas. CLOVE syndrome is characterized by congenital lipomatous overgrowths, vascular malformations, and epidermal nevi. The patient presented with skeletal and dental asymmetry, enlargement of the maxilla, and three asymptomatic lesions on the dorsal tongue measuring 5mm. Histopathological examination of an excisional biopsy confirmed mucosal neuroma, which has not previously been reported in association with CLOVE syndrome. Further investigation is needed to determine the etiology of the mucosal neuromas in this patient.

Uploaded by

Asad Ali Khan Ashar
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOC, PDF, TXT or read online on Scribd
246 views

Format and Content of An Example Case Report Abstract

This case report abstract summarizes the presentation of a 14-year-old girl with CLOVE syndrome who also presented with oral mucosal neuromas. CLOVE syndrome is characterized by congenital lipomatous overgrowths, vascular malformations, and epidermal nevi. The patient presented with skeletal and dental asymmetry, enlargement of the maxilla, and three asymptomatic lesions on the dorsal tongue measuring 5mm. Histopathological examination of an excisional biopsy confirmed mucosal neuroma, which has not previously been reported in association with CLOVE syndrome. Further investigation is needed to determine the etiology of the mucosal neuromas in this patient.

Uploaded by

Asad Ali Khan Ashar
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOC, PDF, TXT or read online on Scribd
You are on page 1/ 1

Format and content of an example case report abstract

Oral mucosal neuroma presenting in a patient with


Clove syndrome
E. A. AKBARI & H. ZAITOUN
Paediatric Dentistry, Charles Clifford Dental Hospital, Sheffield,
UK
Introduction: CLOVE syndrome is a disorder comprising congenital
lipomatous overgrowth, vascular malformations and epidermal
nevi. It is a recently defined syndrome following
reclassification of Proteus syndrome, which is a progressive disease,
in contrast to the non-progressive nature of CLOVE. Vascular
malformations in CLOVE are typically truncal and there is
disregulated adipose tissue deposition, scoliosis and enlarged
bony structures. We describe a female with features of CLOVE
syndrome and mucosal neuroma of the tongue, not previously
described in association with CLOVE syndrome.
Case reports: A 14-year-old girl was referred for management of
dental trauma, crowding and a 7-month history of three asymptomatic
dorsal tongue lesions. Clinical examination revealed skeletal
and dental asymmetry with midline shift to the left,
enlargement of the maxilla with right-sided macroglosia. There
was an enamel-dentine fracture 11, and 23 was buccally displaced
and causing soft tissue trauma. There were three soft tissue
lesions on the dorsum of the tongue measuring 5 mm in diameter
with no ulceration or erythema. Comprehensive dental care under
general anaesthesia was undertaken including excisional biopsy
of the hyperplastic tongue tissue. Histopathology confirmed
mucosal neuroma. Mucosal neuromas have not been previously
reported in CLOVE syndrome and may be a new finding or an
indication the patient has Multiple Endocrine Neoplasia type 2B
for which investigations are currently under way.
Comments: Dentists may be the first clinicians to detect oral
lesions which present as part of a systemic condition. Further
investigation is required to determine the aetiology of mucosal
neuroma in this patient.
[Extract taken from Int J Paed Dent 2013; Vol 23. Issue Supplement s1: 89]

You might also like