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Assignment 2

This document provides a problem statement for a bioreactor design project using superPro software. The problem involves simulating a batch fermentation reaction that produces biomass from media, oxygen, water and other components. Students are asked to determine the time required to completely consume the reaction components and identify the limiting reactant by running the simulation.

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273 views

Assignment 2

This document provides a problem statement for a bioreactor design project using superPro software. The problem involves simulating a batch fermentation reaction that produces biomass from media, oxygen, water and other components. Students are asked to determine the time required to completely consume the reaction components and identify the limiting reactant by running the simulation.

Uploaded by

bellasyazana
Copyright
© © All Rights Reserved
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd
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CBB 40104 Bioplant Design Project 2

Exercise 2 (using superPro software)


Problem Statement:
Understanding cell growth rates and the effects of environmental conditions of growth is a key
aspect of biological engineering. The most common and versatile method of cell growth analysis
used throughout industry is batch fermentation in a bioreactor. The fermentation bioreactor
enables cell growth to take place under well-defined operating conditions. Below is a typical
overall of fermentation reaction.

100 Media

70 Oxygen

28 Biomass + 70 Carbon Dioxide + 10 Impurity + 2 MAB

60 Water

All of the feed streams enter the reactor at STP. 7800 kg of water is fed to the reactor at a
flowrate of 100 L/min with a setup time of 5 minutes. 380 kg media is also fed to the reactor at a
flowrate of 10 kg/min with a setup time of 20 minutes.
This fermentation cycle occurs at a temperature of 37oC with a constant heat rate of 0.5oC/min.
The calculated reaction rate refers to biomass formation (dX/dt) since biomass was selected as
the Rate Reference Component with a max of 0.2 h-1. Media is the only substrate with a Ks
value of 35 mg/L. The reaction is first order in biomass and has an enthalpy of -3697 kcal/kg at
an oxygen reference temperature of 37oC. The product will be cooled to 5oC using glycol, which
has a cooling rate of 0.5oC/min and will be transferred out of the fermentor in a process time of
272 minutes. Determine the amount of time required to completely consume the reaction
components and what is the limiting reactant for this system.

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